Motif ID: Rora

Z-value: 0.941


Transcription factors associated with Rora:

Gene SymbolEntrez IDGene Name
Rora ENSMUSG00000032238.11 Rora

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Roramm10_v2_chr9_+_68653761_68653786-0.047.5e-01Click!


Activity profile for motif Rora.

activity profile for motif Rora


Sorted Z-values histogram for motif Rora

Sorted Z-values for motif Rora



Network of associatons between targets according to the STRING database.



First level regulatory network of Rora

PNG image of the network

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Top targets:


Showing 1 to 20 of 192 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_66801577 16.988 ENSMUST00000168589.1
Sla
src-like adaptor
chr1_+_32172711 10.514 ENSMUST00000027226.5
Khdrbs2
KH domain containing, RNA binding, signal transduction associated 2
chr7_-_79386943 10.180 ENSMUST00000053718.8
ENSMUST00000179243.1
Rlbp1

retinaldehyde binding protein 1

chr14_+_64589802 9.996 ENSMUST00000180610.1
A930011O12Rik
RIKEN cDNA A930011O12 gene
chr5_+_37028329 9.502 ENSMUST00000173836.1
Jakmip1
janus kinase and microtubule interacting protein 1
chr7_-_25005895 7.945 ENSMUST00000102858.3
ENSMUST00000080882.6
Atp1a3

ATPase, Na+/K+ transporting, alpha 3 polypeptide

chr3_-_107517321 7.905 ENSMUST00000166892.1
Slc6a17
solute carrier family 6 (neurotransmitter transporter), member 17
chr2_+_170731807 7.626 ENSMUST00000029075.4
Dok5
docking protein 5
chr19_-_46327121 7.616 ENSMUST00000041391.4
ENSMUST00000096029.5
Psd

pleckstrin and Sec7 domain containing

chr17_-_43667015 7.466 ENSMUST00000024705.4
Slc25a27
solute carrier family 25, member 27
chr19_-_37207293 7.167 ENSMUST00000132580.1
ENSMUST00000079754.4
ENSMUST00000136286.1
ENSMUST00000126188.1
ENSMUST00000126781.1
Cpeb3




cytoplasmic polyadenylation element binding protein 3




chr16_+_11406618 7.081 ENSMUST00000122168.1
Snx29
sorting nexin 29
chr5_-_106696819 6.863 ENSMUST00000127434.1
ENSMUST00000112696.1
ENSMUST00000112698.1
Zfp644


zinc finger protein 644


chr11_+_98741805 6.749 ENSMUST00000064187.5
Thra
thyroid hormone receptor alpha
chr2_+_178119166 6.708 ENSMUST00000108916.1
Phactr3
phosphatase and actin regulator 3
chr1_+_159737510 6.488 ENSMUST00000111669.3
Tnr
tenascin R
chr2_+_29965560 6.392 ENSMUST00000113717.1
ENSMUST00000113719.2
ENSMUST00000100225.2
ENSMUST00000113741.1
ENSMUST00000095083.4
ENSMUST00000046257.7
Sptan1





spectrin alpha, non-erythrocytic 1





chr15_+_99224976 6.380 ENSMUST00000041415.3
Kcnh3
potassium voltage-gated channel, subfamily H (eag-related), member 3
chr11_+_113619318 6.379 ENSMUST00000146390.2
ENSMUST00000106630.1
Sstr2

somatostatin receptor 2

chr7_-_31126945 6.263 ENSMUST00000098548.4
Scn1b
sodium channel, voltage-gated, type I, beta

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 101 entries
Log-likelihood per target Total log-likelihoodTermDescription
4.3 12.9 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
3.6 10.8 GO:0021933 radial glia guided migration of cerebellar granule cell(GO:0021933)
0.9 10.3 GO:0036376 sodium ion export from cell(GO:0036376)
0.1 10.2 GO:0007601 visual perception(GO:0007601)
2.9 8.7 GO:0071929 alpha-tubulin acetylation(GO:0071929)
1.6 7.9 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 7.8 GO:0007411 axon guidance(GO:0007411)
0.8 7.6 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.3 7.6 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
1.9 7.5 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
1.2 7.1 GO:1901524 regulation of autophagosome maturation(GO:1901096) regulation of macromitophagy(GO:1901524) negative regulation of macromitophagy(GO:1901525)
2.2 6.7 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.1 6.6 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
2.2 6.5 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
1.1 6.4 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.7 6.4 GO:0030432 peristalsis(GO:0030432)
0.2 6.4 GO:0051693 actin filament capping(GO:0051693)
2.1 6.3 GO:0086017 Purkinje myocyte action potential(GO:0086017)
0.9 6.0 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.6 5.6 GO:0071420 cellular response to histamine(GO:0071420)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 56 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 22.2 GO:0005768 endosome(GO:0005768)
0.1 16.2 GO:0019898 extrinsic component of membrane(GO:0019898)
0.7 13.1 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 12.3 GO:0008021 synaptic vesicle(GO:0008021)
0.0 12.0 GO:0044297 cell body(GO:0044297)
0.1 11.7 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
1.5 10.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 8.9 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
1.4 8.7 GO:0097427 microtubule bundle(GO:0097427)
0.0 8.7 GO:0043005 neuron projection(GO:0043005)
0.1 7.3 GO:0031594 neuromuscular junction(GO:0031594)
0.0 6.9 GO:0005887 integral component of plasma membrane(GO:0005887)
2.2 6.5 GO:0072534 perineuronal net(GO:0072534)
0.0 6.5 GO:0031461 cullin-RING ubiquitin ligase complex(GO:0031461)
2.1 6.4 GO:0032437 cuticular plate(GO:0032437)
0.4 6.3 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.7 5.9 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 5.9 GO:0031965 nuclear membrane(GO:0031965)
0.3 5.6 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.2 5.4 GO:0043194 axon initial segment(GO:0043194)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 82 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 13.1 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.8 12.9 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
2.0 11.9 GO:0019841 retinol binding(GO:0019841)
0.5 10.5 GO:0008143 poly(A) binding(GO:0008143)
1.0 10.3 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.0 9.7 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.1 9.6 GO:0061733 peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.2 9.5 GO:0030507 spectrin binding(GO:0030507)
0.5 8.2 GO:0050811 GABA receptor binding(GO:0050811)
0.5 7.9 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.2 7.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2 7.6 GO:0005158 insulin receptor binding(GO:0005158)
0.0 7.2 GO:0035091 phosphatidylinositol binding(GO:0035091)
2.2 6.7 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.2 6.7 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.4 6.5 GO:0046625 sphingolipid binding(GO:0046625)
2.1 6.4 GO:0004994 somatostatin receptor activity(GO:0004994)
1.1 6.4 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.9 6.3 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 6.2 GO:0005096 GTPase activator activity(GO:0005096)