Motif ID: Rorc_Nr1d1

Z-value: 0.494

Transcription factors associated with Rorc_Nr1d1:

Gene SymbolEntrez IDGene Name
Nr1d1 ENSMUSG00000020889.11 Nr1d1
Rorc ENSMUSG00000028150.8 Rorc

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rorcmm10_v2_chr3_+_94377505_943775270.291.5e-02Click!
Nr1d1mm10_v2_chr11_-_98775333_987753540.281.9e-02Click!


Activity profile for motif Rorc_Nr1d1.

activity profile for motif Rorc_Nr1d1


Sorted Z-values histogram for motif Rorc_Nr1d1

Sorted Z-values for motif Rorc_Nr1d1



Network of associatons between targets according to the STRING database.



First level regulatory network of Rorc_Nr1d1

PNG image of the network

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Top targets:


Showing 1 to 20 of 106 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_79386943 6.116 ENSMUST00000053718.8
ENSMUST00000179243.1
 Rlbp1

retinaldehyde binding protein 1

chr11_-_98329641 4.131 ENSMUST00000041685.6
 Neurod2
neurogenic differentiation 2
chr2_+_90885860 3.958 ENSMUST00000111466.2
 C1qtnf4
C1q and tumor necrosis factor related protein 4
chr3_-_89764581 2.627 ENSMUST00000029562.3
 Chrnb2
cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)
chr7_+_45705088 2.425 ENSMUST00000080885.3
 Dbp
D site albumin promoter binding protein
chr1_-_14310198 2.331 ENSMUST00000168081.2
ENSMUST00000027066.6
 Eya1

eyes absent 1 homolog (Drosophila)

chr1_-_52490736 2.318 ENSMUST00000170269.1
 Nab1
Ngfi-A binding protein 1
chr12_-_34528844 2.296 ENSMUST00000110819.2
 Hdac9
histone deacetylase 9
chr10_+_57784859 2.022 ENSMUST00000020024.5
 Fabp7
fatty acid binding protein 7, brain
chr11_+_98348404 1.984 ENSMUST00000078694.6
 Ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr10_+_106470281 1.774 ENSMUST00000029404.9
ENSMUST00000169303.1
 Ppfia2

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

chr3_-_84304762 1.745 ENSMUST00000107692.1
 Trim2
tripartite motif-containing 2
chrX_+_103422010 1.712 ENSMUST00000182089.1
 Gm26992
predicted gene, 26992
chr7_+_113207465 1.672 ENSMUST00000047321.7
 Arntl
aryl hydrocarbon receptor nuclear translocator-like
chr2_-_170427828 1.634 ENSMUST00000013667.2
ENSMUST00000109152.2
ENSMUST00000068137.4
 Bcas1


breast carcinoma amplified sequence 1


chrX_-_143933204 1.515 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
 Dcx


doublecortin


chr19_+_26623419 1.509 ENSMUST00000176584.1
 Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr15_-_65014904 1.419 ENSMUST00000110100.2
 Gm21961
predicted gene, 21961
chr6_-_88874045 1.418 ENSMUST00000038409.5
 Podxl2
podocalyxin-like 2
chr3_+_79884496 1.402 ENSMUST00000118853.1
 Fam198b
family with sequence similarity 198, member B

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 44 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.8 GO:0007601 visual perception(GO:0007601)
1.4 4.1 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.3 3.3 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.9 2.6 GO:0060084 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747) synaptic transmission involved in micturition(GO:0060084)
0.1 2.4 GO:0021860 pyramidal neuron development(GO:0021860)
0.1 2.4 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.4 2.3 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 2.2 GO:0007623 circadian rhythm(GO:0007623)
0.7 2.0 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.1 2.0 GO:0060134 prepulse inhibition(GO:0060134)
0.6 1.7 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.2 1.5 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.1 1.4 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.4 1.3 GO:0007210 serotonin receptor signaling pathway(GO:0007210)
0.4 1.2 GO:1902336 neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of retinal ganglion cell axon guidance(GO:1902336)
0.2 1.2 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 1.2 GO:1902563 regulation of neutrophil activation(GO:1902563)
0.1 1.1 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.1 0.9 GO:0032811 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) negative regulation of epinephrine secretion(GO:0032811)
0.1 0.9 GO:0050957 equilibrioception(GO:0050957)

Gene overrepresentation in cellular_component category:

Showing 1 to 16 of 16 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 11.6 GO:0044297 cell body(GO:0044297)
0.2 2.6 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 2.3 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 2.3 GO:0032993 protein-DNA complex(GO:0032993)
0.0 2.0 GO:0005923 bicellular tight junction(GO:0005923)
0.2 1.7 GO:0033391 chromatoid body(GO:0033391)
0.1 1.5 GO:0071564 npBAF complex(GO:0071564)
0.2 0.9 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 0.9 GO:0032420 stereocilium(GO:0032420)
0.0 0.9 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.5 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 0.3 GO:1990879 CST complex(GO:1990879)
0.1 0.2 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.2 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 35 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.0 6.1 GO:0019841 retinol binding(GO:0019841)
0.1 5.7 GO:0005125 cytokine activity(GO:0005125)
0.1 4.1 GO:0070888 E-box binding(GO:0070888)
0.4 3.9 GO:0004889 acetylcholine-activated cation-selective channel activity(GO:0004889)
0.1 2.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 2.4 GO:0017124 SH3 domain binding(GO:0017124)
0.1 2.3 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.7 2.0 GO:0031752 D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752)
0.3 1.7 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 1.6 GO:0017022 myosin binding(GO:0017022)
0.0 1.5 GO:0005504 fatty acid binding(GO:0005504)
0.4 1.2 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.2 1.0 GO:0018121 imidazoleglycerol-phosphate synthase activity(GO:0000107) NAD(P)-cysteine ADP-ribosyltransferase activity(GO:0018071) NAD(P)-asparagine ADP-ribosyltransferase activity(GO:0018121) NAD(P)-serine ADP-ribosyltransferase activity(GO:0018127) 7-cyano-7-deazaguanine tRNA-ribosyltransferase activity(GO:0043867) purine deoxyribosyltransferase activity(GO:0044102)
0.2 0.9 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.9 GO:0043531 ADP binding(GO:0043531)
0.1 0.8 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.8 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.8 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 0.7 GO:0004658 propionyl-CoA carboxylase activity(GO:0004658)
0.1 0.7 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)