Motif ID: Rxra
Z-value: 0.659
Transcription factors associated with Rxra:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Rxra | ENSMUSG00000015846.8 | Rxra |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Rxra | mm10_v2_chr2_+_27677201_27677229 | -0.76 | 2.0e-14 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.0 | 9.1 | GO:0071929 | alpha-tubulin acetylation(GO:0071929) |
| 1.3 | 3.8 | GO:0033364 | endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510) mast cell secretory granule organization(GO:0033364) |
| 1.2 | 4.9 | GO:0033540 | fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540) |
| 1.0 | 4.1 | GO:0002175 | protein localization to paranode region of axon(GO:0002175) |
| 0.8 | 4.1 | GO:0051835 | positive regulation of synapse structural plasticity(GO:0051835) |
| 0.6 | 1.9 | GO:0072008 | glomerular mesangial cell differentiation(GO:0072008) glomerular mesangial cell development(GO:0072144) |
| 0.6 | 1.9 | GO:0097155 | fasciculation of sensory neuron axon(GO:0097155) |
| 0.5 | 17.3 | GO:0048488 | synaptic vesicle endocytosis(GO:0048488) |
| 0.4 | 5.8 | GO:0051205 | protein insertion into membrane(GO:0051205) |
| 0.4 | 3.3 | GO:0010793 | regulation of mRNA export from nucleus(GO:0010793) regulation of ribonucleoprotein complex localization(GO:2000197) |
| 0.4 | 5.7 | GO:1904294 | positive regulation of ERAD pathway(GO:1904294) |
| 0.3 | 2.3 | GO:2000809 | positive regulation of synaptic vesicle clustering(GO:2000809) |
| 0.3 | 1.6 | GO:1901668 | regulation of superoxide dismutase activity(GO:1901668) |
| 0.3 | 0.9 | GO:0046098 | guanine metabolic process(GO:0046098) |
| 0.3 | 1.1 | GO:0097428 | protein maturation by iron-sulfur cluster transfer(GO:0097428) |
| 0.2 | 1.2 | GO:0071985 | multivesicular body sorting pathway(GO:0071985) |
| 0.2 | 0.7 | GO:0016056 | rhodopsin mediated signaling pathway(GO:0016056) |
| 0.2 | 0.6 | GO:0010845 | positive regulation of reciprocal meiotic recombination(GO:0010845) |
| 0.2 | 3.4 | GO:0001539 | cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285) |
| 0.2 | 3.1 | GO:0010758 | regulation of macrophage chemotaxis(GO:0010758) |
| 0.2 | 4.9 | GO:0009409 | response to cold(GO:0009409) |
| 0.2 | 2.6 | GO:0070050 | neuron cellular homeostasis(GO:0070050) |
| 0.2 | 5.5 | GO:1900078 | positive regulation of cellular response to insulin stimulus(GO:1900078) |
| 0.2 | 3.3 | GO:0035025 | positive regulation of Rho protein signal transduction(GO:0035025) |
| 0.2 | 2.9 | GO:0051974 | negative regulation of telomerase activity(GO:0051974) |
| 0.1 | 1.7 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
| 0.1 | 1.1 | GO:0036376 | sodium ion export from cell(GO:0036376) |
| 0.1 | 1.1 | GO:0016559 | peroxisome fission(GO:0016559) |
| 0.1 | 0.7 | GO:0032264 | IMP salvage(GO:0032264) |
| 0.1 | 0.3 | GO:0031590 | wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591) |
| 0.1 | 1.2 | GO:0000042 | protein targeting to Golgi(GO:0000042) |
| 0.1 | 1.7 | GO:0010039 | response to iron ion(GO:0010039) |
| 0.1 | 1.2 | GO:0006744 | ubiquinone biosynthetic process(GO:0006744) |
| 0.1 | 1.4 | GO:1900037 | regulation of cellular response to hypoxia(GO:1900037) |
| 0.1 | 0.7 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
| 0.1 | 4.6 | GO:0015807 | L-amino acid transport(GO:0015807) |
| 0.1 | 2.1 | GO:2000249 | regulation of actin cytoskeleton reorganization(GO:2000249) |
| 0.0 | 3.6 | GO:0046847 | filopodium assembly(GO:0046847) |
| 0.0 | 1.3 | GO:0046827 | positive regulation of protein export from nucleus(GO:0046827) |
| 0.0 | 2.3 | GO:0045668 | negative regulation of osteoblast differentiation(GO:0045668) |
| 0.0 | 3.7 | GO:0090263 | positive regulation of canonical Wnt signaling pathway(GO:0090263) |
| 0.0 | 0.8 | GO:0048268 | clathrin coat assembly(GO:0048268) |
| 0.0 | 0.4 | GO:2001197 | regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197) |
| 0.0 | 0.9 | GO:0015991 | energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662) |
| 0.0 | 2.2 | GO:0010508 | positive regulation of autophagy(GO:0010508) |
| 0.0 | 0.8 | GO:1900047 | negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047) |
| 0.0 | 0.7 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
| 0.0 | 0.7 | GO:0090200 | positive regulation of release of cytochrome c from mitochondria(GO:0090200) |
| 0.0 | 1.6 | GO:0032091 | negative regulation of protein binding(GO:0032091) |
| 0.0 | 1.9 | GO:0007018 | microtubule-based movement(GO:0007018) |
| 0.0 | 3.0 | GO:0042787 | protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787) |
| 0.0 | 0.3 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 0.0 | 0.2 | GO:0006654 | phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473) |
| 0.0 | 1.5 | GO:0018107 | peptidyl-threonine phosphorylation(GO:0018107) |
| 0.0 | 0.2 | GO:0090161 | Golgi ribbon formation(GO:0090161) |
| 0.0 | 1.1 | GO:0051289 | protein homotetramerization(GO:0051289) |
| 0.0 | 1.4 | GO:0030509 | BMP signaling pathway(GO:0030509) |
| 0.0 | 0.2 | GO:0048096 | chromatin-mediated maintenance of transcription(GO:0048096) |
| 0.0 | 1.8 | GO:0002244 | hematopoietic progenitor cell differentiation(GO:0002244) |
| 0.0 | 0.1 | GO:0045717 | negative regulation of fatty acid biosynthetic process(GO:0045717) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.5 | 9.1 | GO:0097427 | microtubule bundle(GO:0097427) |
| 1.0 | 4.1 | GO:0097454 | Schwann cell microvillus(GO:0097454) |
| 1.0 | 2.9 | GO:1990879 | CST complex(GO:1990879) |
| 0.9 | 3.6 | GO:0045098 | type III intermediate filament(GO:0045098) |
| 0.5 | 2.3 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.4 | 4.8 | GO:0043083 | synaptic cleft(GO:0043083) |
| 0.4 | 3.3 | GO:0000347 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
| 0.3 | 1.9 | GO:0036157 | outer dynein arm(GO:0036157) |
| 0.3 | 1.7 | GO:0031314 | mitochondrial inner membrane presequence translocase complex(GO:0005744) extrinsic component of mitochondrial inner membrane(GO:0031314) |
| 0.3 | 2.1 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500) |
| 0.3 | 0.8 | GO:0055087 | Ski complex(GO:0055087) |
| 0.2 | 3.4 | GO:0031512 | motile primary cilium(GO:0031512) |
| 0.1 | 4.7 | GO:0060170 | ciliary membrane(GO:0060170) |
| 0.1 | 0.9 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
| 0.1 | 1.5 | GO:0045120 | transcription factor TFIID complex(GO:0005669) pronucleus(GO:0045120) |
| 0.1 | 4.9 | GO:0005778 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
| 0.0 | 1.1 | GO:0044439 | microbody part(GO:0044438) peroxisomal part(GO:0044439) |
| 0.0 | 1.4 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
| 0.0 | 0.4 | GO:0045180 | basal cortex(GO:0045180) |
| 0.0 | 1.9 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.0 | 2.4 | GO:0005776 | autophagosome(GO:0005776) |
| 0.0 | 3.9 | GO:0043195 | terminal bouton(GO:0043195) |
| 0.0 | 0.3 | GO:0000812 | Swr1 complex(GO:0000812) |
| 0.0 | 1.7 | GO:0031526 | brush border membrane(GO:0031526) |
| 0.0 | 3.3 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
| 0.0 | 0.9 | GO:0005637 | nuclear inner membrane(GO:0005637) |
| 0.0 | 0.1 | GO:0036449 | microtubule minus-end(GO:0036449) |
| 0.0 | 0.6 | GO:0009986 | cell surface(GO:0009986) |
| 0.0 | 1.6 | GO:0043204 | perikaryon(GO:0043204) |
| 0.0 | 2.4 | GO:0070382 | exocytic vesicle(GO:0070382) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 4.1 | GO:0030160 | GKAP/Homer scaffold activity(GO:0030160) |
| 0.8 | 4.1 | GO:0086080 | protein binding involved in heterotypic cell-cell adhesion(GO:0086080) |
| 0.8 | 4.9 | GO:0016401 | palmitoyl-CoA oxidase activity(GO:0016401) |
| 0.6 | 2.4 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 0.5 | 1.9 | GO:0042731 | PH domain binding(GO:0042731) |
| 0.4 | 2.1 | GO:0030942 | endoplasmic reticulum signal peptide binding(GO:0030942) |
| 0.4 | 2.3 | GO:0070699 | type II activin receptor binding(GO:0070699) |
| 0.3 | 1.7 | GO:0000293 | ferric-chelate reductase activity(GO:0000293) |
| 0.3 | 2.9 | GO:0010521 | telomerase inhibitor activity(GO:0010521) |
| 0.2 | 3.6 | GO:0019215 | intermediate filament binding(GO:0019215) |
| 0.2 | 2.1 | GO:0038191 | neuropilin binding(GO:0038191) |
| 0.2 | 3.3 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 0.2 | 3.8 | GO:0004029 | aldehyde dehydrogenase (NAD) activity(GO:0004029) |
| 0.2 | 3.6 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.1 | 0.7 | GO:0004724 | magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724) |
| 0.1 | 10.3 | GO:0061733 | peptide-lysine-N-acetyltransferase activity(GO:0061733) |
| 0.1 | 0.6 | GO:0033691 | sialic acid binding(GO:0033691) |
| 0.1 | 1.1 | GO:0008556 | sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556) |
| 0.1 | 1.5 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 0.1 | 4.6 | GO:0015175 | neutral amino acid transmembrane transporter activity(GO:0015175) |
| 0.1 | 3.7 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.1 | 0.7 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
| 0.1 | 1.0 | GO:0042500 | aspartic endopeptidase activity, intramembrane cleaving(GO:0042500) |
| 0.1 | 0.7 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
| 0.1 | 0.8 | GO:0030976 | thiamine pyrophosphate binding(GO:0030976) |
| 0.1 | 1.4 | GO:0015026 | coreceptor activity(GO:0015026) |
| 0.1 | 0.8 | GO:0016701 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
| 0.1 | 5.5 | GO:0003707 | steroid hormone receptor activity(GO:0003707) |
| 0.1 | 1.1 | GO:0016290 | palmitoyl-CoA hydrolase activity(GO:0016290) |
| 0.1 | 2.3 | GO:0008028 | monocarboxylic acid transmembrane transporter activity(GO:0008028) |
| 0.1 | 1.3 | GO:0017161 | phosphohistidine phosphatase activity(GO:0008969) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) NADP phosphatase activity(GO:0019178) 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity(GO:0043726) phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052867) IDP phosphatase activity(GO:1990003) |
| 0.0 | 2.3 | GO:0051019 | mitogen-activated protein kinase binding(GO:0051019) |
| 0.0 | 1.1 | GO:0016854 | racemase and epimerase activity(GO:0016854) |
| 0.0 | 1.1 | GO:0008198 | ferrous iron binding(GO:0008198) |
| 0.0 | 0.9 | GO:0016814 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814) |
| 0.0 | 0.9 | GO:0046961 | proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
| 0.0 | 0.8 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
| 0.0 | 0.3 | GO:1990405 | protein antigen binding(GO:1990405) |
| 0.0 | 0.6 | GO:0042800 | histone methyltransferase activity (H3-K4 specific)(GO:0042800) |
| 0.0 | 1.9 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.0 | 1.6 | GO:0005080 | protein kinase C binding(GO:0005080) |
| 0.0 | 5.2 | GO:0008017 | microtubule binding(GO:0008017) |
| 0.0 | 0.1 | GO:0048039 | ubiquinone binding(GO:0048039) |
| 0.0 | 0.4 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
| 0.0 | 12.0 | GO:0008289 | lipid binding(GO:0008289) |
| 0.0 | 0.5 | GO:0008327 | methyl-CpG binding(GO:0008327) |
| 0.0 | 6.9 | GO:0005509 | calcium ion binding(GO:0005509) |
| 0.0 | 0.9 | GO:0043130 | ubiquitin binding(GO:0043130) |
| 0.0 | 0.2 | GO:0035173 | histone kinase activity(GO:0035173) |
| 0.0 | 2.7 | GO:0003729 | mRNA binding(GO:0003729) |
| 0.0 | 1.9 | GO:0004930 | G-protein coupled receptor activity(GO:0004930) |
