Motif ID: Rxrb

Z-value: 0.810


Transcription factors associated with Rxrb:

Gene SymbolEntrez IDGene Name
Rxrb ENSMUSG00000039656.10 Rxrb

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rxrbmm10_v2_chr17_+_34031787_34031821-0.523.2e-06Click!


Activity profile for motif Rxrb.

activity profile for motif Rxrb


Sorted Z-values histogram for motif Rxrb

Sorted Z-values for motif Rxrb



Network of associatons between targets according to the STRING database.



First level regulatory network of Rxrb

PNG image of the network

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Top targets:


Showing 1 to 20 of 116 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_136143497 13.240 ENSMUST00000008016.2
 Id3
inhibitor of DNA binding 3
chr14_-_118052235 10.930 ENSMUST00000022725.2
 Dct
dopachrome tautomerase
chr4_-_117178726 10.886 ENSMUST00000153953.1
ENSMUST00000106436.1
 Kif2c

kinesin family member 2C

chr10_+_93641041 10.169 ENSMUST00000020204.4
 Ntn4
netrin 4
chr18_+_57142782 9.450 ENSMUST00000139892.1
 Megf10
multiple EGF-like-domains 10
chr4_+_44300876 7.944 ENSMUST00000045607.5
 Melk
maternal embryonic leucine zipper kinase
chr10_-_88146867 7.715 ENSMUST00000164121.1
ENSMUST00000164803.1
ENSMUST00000168163.1
ENSMUST00000048518.9
 Parpbp



PARP1 binding protein



chr5_-_116422858 7.287 ENSMUST00000036991.4
 Hspb8
heat shock protein 8
chr6_-_23248264 7.131 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr5_+_110839973 6.544 ENSMUST00000066160.1
 Chek2
checkpoint kinase 2
chr1_+_84839833 5.986 ENSMUST00000097672.3
 Fbxo36
F-box protein 36
chr6_+_113531675 5.776 ENSMUST00000036340.5
ENSMUST00000101051.2
 Fancd2

Fanconi anemia, complementation group D2

chr11_-_40733373 5.682 ENSMUST00000020579.8
 Hmmr
hyaluronan mediated motility receptor (RHAMM)
chrX_-_23365044 5.151 ENSMUST00000115313.1
 Klhl13
kelch-like 13
chr1_+_146420434 4.739 ENSMUST00000163646.1
 Gm5263
predicted gene 5263
chr15_-_78529617 4.567 ENSMUST00000023075.8
 C1qtnf6
C1q and tumor necrosis factor related protein 6
chr11_+_40733936 4.468 ENSMUST00000127382.1
 Nudcd2
NudC domain containing 2
chr8_+_72135247 4.111 ENSMUST00000003575.9
 Tpm4
tropomyosin 4
chr18_-_80713062 4.065 ENSMUST00000170905.1
ENSMUST00000078049.4
 Nfatc1

nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1

chr5_+_137630116 4.010 ENSMUST00000175968.1
 Lrch4
leucine-rich repeats and calponin homology (CH) domain containing 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 58 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 13.2 GO:0071398 cellular response to fatty acid(GO:0071398)
2.2 10.9 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
1.8 10.9 GO:0006570 tyrosine metabolic process(GO:0006570)
2.0 10.2 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
1.9 9.5 GO:0014719 skeletal muscle satellite cell activation(GO:0014719)
0.2 7.9 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631)
1.1 7.7 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
1.2 7.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.5 7.1 GO:0010388 cullin deneddylation(GO:0010388)
1.6 6.5 GO:1903463 mitotic cell cycle phase(GO:0098763) regulation of mitotic cell cycle DNA replication(GO:1903463)
0.0 6.3 GO:0051028 mRNA transport(GO:0051028)
0.2 6.0 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.8 5.8 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.2 5.5 GO:0051894 integrin activation(GO:0033622) positive regulation of focal adhesion assembly(GO:0051894)
0.2 4.6 GO:0070208 protein heterotrimerization(GO:0070208)
0.6 4.2 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
1.4 4.1 GO:0060854 patterning of lymph vessels(GO:0060854)
0.2 3.8 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.3 3.7 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.2 3.6 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 41 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 11.6 GO:0015630 microtubule cytoskeleton(GO:0015630)
0.4 10.9 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 10.1 GO:0005581 collagen trimer(GO:0005581)
0.4 9.5 GO:0001891 phagocytic cup(GO:0001891)
0.3 9.5 GO:0035371 microtubule plus-end(GO:0035371)
0.1 8.7 GO:0005604 basement membrane(GO:0005604)
0.1 8.3 GO:0000776 kinetochore(GO:0000776)
0.0 8.3 GO:0005938 cell cortex(GO:0005938)
0.0 8.1 GO:0000785 chromatin(GO:0000785)
0.0 6.5 GO:0000781 chromosome, telomeric region(GO:0000781)
0.6 6.3 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 5.8 GO:0000793 condensed chromosome(GO:0000793)
0.0 5.1 GO:0043235 receptor complex(GO:0043235)
0.0 4.8 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.2 4.1 GO:0002102 podosome(GO:0002102)
0.3 3.8 GO:0005916 fascia adherens(GO:0005916)
0.2 3.2 GO:0031011 Ino80 complex(GO:0031011)
0.1 3.1 GO:0034707 chloride channel complex(GO:0034707)
1.0 3.0 GO:0031088 platelet dense granule membrane(GO:0031088)
0.9 2.7 GO:0071953 elastic fiber(GO:0071953)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 38 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 13.2 GO:0005504 fatty acid binding(GO:0005504)
1.7 11.7 GO:0043237 laminin-1 binding(GO:0043237)
0.8 10.9 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.7 10.1 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 7.9 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 7.1 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 6.6 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.4 5.8 GO:0070182 DNA polymerase binding(GO:0070182)
0.3 5.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 5.5 GO:0005178 integrin binding(GO:0005178)
0.1 5.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.5 5.0 GO:0015245 fatty acid transporter activity(GO:0015245)
0.5 4.1 GO:0001224 RNA polymerase II transcription cofactor binding(GO:0001224)
0.3 3.8 GO:0045294 alpha-catenin binding(GO:0045294)
0.4 3.7 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.3 3.6 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 3.5 GO:0030695 GTPase regulator activity(GO:0030695)
0.1 3.3 GO:0005109 frizzled binding(GO:0005109)
0.2 2.7 GO:0016805 dipeptidase activity(GO:0016805)
0.1 2.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)