Motif ID: Scrt1

Z-value: 2.263


Transcription factors associated with Scrt1:

Gene SymbolEntrez IDGene Name
Scrt1 ENSMUSG00000048385.8 Scrt1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Scrt1mm10_v2_chr15_-_76521902_76522129-0.839.7e-19Click!


Activity profile for motif Scrt1.

activity profile for motif Scrt1


Sorted Z-values histogram for motif Scrt1

Sorted Z-values for motif Scrt1



Network of associatons between targets according to the STRING database.



First level regulatory network of Scrt1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_34649987 37.434 ENSMUST00000099151.2
 Sox2
SRY-box containing gene 2
chr11_+_115163333 34.934 ENSMUST00000021077.3
 Slc9a3r1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr7_-_144939823 33.759 ENSMUST00000093962.4
 Ccnd1
cyclin D1
chr15_-_98004634 32.992 ENSMUST00000131560.1
ENSMUST00000088355.5
 Col2a1

collagen, type II, alpha 1

chr2_+_131234043 32.416 ENSMUST00000041362.5
ENSMUST00000110199.2
 Mavs

mitochondrial antiviral signaling protein

chr10_+_56377300 29.228 ENSMUST00000068581.7
 Gja1
gap junction protein, alpha 1
chr11_-_55419898 29.004 ENSMUST00000108858.1
ENSMUST00000141530.1
 Sparc

secreted acidic cysteine rich glycoprotein

chr13_-_81633119 27.287 ENSMUST00000126444.1
ENSMUST00000128585.1
ENSMUST00000146749.1
ENSMUST00000095585.4
 Gpr98



G protein-coupled receptor 98



chr5_+_33658567 27.137 ENSMUST00000114426.3
 Tacc3
transforming, acidic coiled-coil containing protein 3
chr7_+_110221697 25.935 ENSMUST00000033325.7
 Swap70
SWA-70 protein
chr17_-_25570678 25.695 ENSMUST00000025003.3
ENSMUST00000173447.1
 Sox8

SRY-box containing gene 8

chr7_-_30973367 25.450 ENSMUST00000108116.3
 Lsr
lipolysis stimulated lipoprotein receptor
chr6_+_128375456 24.083 ENSMUST00000100926.2
 4933413G19Rik
RIKEN cDNA 4933413G19 gene
chr5_+_33658550 22.143 ENSMUST00000152847.1
 Tacc3
transforming, acidic coiled-coil containing protein 3
chr8_+_31187317 21.771 ENSMUST00000066173.5
ENSMUST00000161788.1
ENSMUST00000110527.2
ENSMUST00000161502.1
 Fut10



fucosyltransferase 10



chr12_-_91779129 21.687 ENSMUST00000170077.1
 Ston2
stonin 2
chr16_+_16213318 21.546 ENSMUST00000162150.1
ENSMUST00000161342.1
ENSMUST00000039408.2
 Pkp2


plakophilin 2


chr18_+_56432116 21.468 ENSMUST00000070166.5
 Gramd3
GRAM domain containing 3
chr13_+_99100698 21.355 ENSMUST00000181742.1
 Gm807
predicted gene 807
chr2_+_31950257 21.185 ENSMUST00000001920.7
 Aif1l
allograft inflammatory factor 1-like

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 126 entries
Log-likelihood per target Total log-likelihoodTermDescription
4.5 71.4 GO:0030953 astral microtubule organization(GO:0030953)
20.8 62.3 GO:1904274 tricellular tight junction assembly(GO:1904274)
5.8 46.6 GO:0048852 diencephalon morphogenesis(GO:0048852)
11.6 34.9 GO:0042939 renal sodium ion transport(GO:0003096) glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
4.8 33.8 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
2.7 33.0 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
10.8 32.4 GO:0071649 regulation of chemokine (C-C motif) ligand 5 production(GO:0071649)
5.3 31.9 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
2.3 29.3 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
9.7 29.2 GO:0003104 positive regulation of glomerular filtration(GO:0003104) cell communication by chemical coupling(GO:0010643)
0.8 29.0 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.8 27.9 GO:0050873 brown fat cell differentiation(GO:0050873)
8.6 25.7 GO:0072034 renal vesicle induction(GO:0072034)
3.1 21.8 GO:1901724 positive regulation of cell proliferation involved in kidney development(GO:1901724)
1.5 21.8 GO:0036065 fucosylation(GO:0036065)
7.2 21.5 GO:0086069 desmosome assembly(GO:0002159) adherens junction maintenance(GO:0034334) intermediate filament bundle assembly(GO:0045110) maintenance of organ identity(GO:0048496) bundle of His cell to Purkinje myocyte communication(GO:0086069)
5.2 20.9 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
1.7 20.8 GO:0044458 motile cilium assembly(GO:0044458)
2.6 20.5 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
2.0 19.8 GO:0090527 actin filament reorganization(GO:0090527)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 81 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 89.3 GO:0005813 centrosome(GO:0005813)
10.4 62.3 GO:0061689 tricellular tight junction(GO:0061689)
0.3 53.5 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.7 53.3 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 45.5 GO:0005794 Golgi apparatus(GO:0005794)
0.3 40.7 GO:0005884 actin filament(GO:0005884)
7.0 34.9 GO:0032426 stereocilium tip(GO:0032426)
0.7 34.5 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
2.5 33.0 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
2.7 29.2 GO:0005916 fascia adherens(GO:0005916)
7.3 29.0 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 28.2 GO:0005681 spliceosomal complex(GO:0005681)
0.1 28.1 GO:0031012 extracellular matrix(GO:0031012)
0.3 25.0 GO:0005814 centriole(GO:0005814)
0.2 24.9 GO:0031514 motile cilium(GO:0031514)
0.3 22.4 GO:0005881 cytoplasmic microtubule(GO:0005881)
2.2 21.5 GO:0030057 desmosome(GO:0030057)
0.2 20.7 GO:0005604 basement membrane(GO:0005604)
4.1 20.5 GO:0033010 paranodal junction(GO:0033010)
0.2 19.5 GO:0030136 clathrin-coated vesicle(GO:0030136)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 101 entries
Log-likelihood per target Total log-likelihoodTermDescription
4.0 71.7 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.2 52.2 GO:0003924 GTPase activity(GO:0003924)
2.7 51.7 GO:0035198 miRNA binding(GO:0035198)
0.7 44.9 GO:0005518 collagen binding(GO:0005518)
4.2 38.1 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.4 36.5 GO:0005178 integrin binding(GO:0005178)
1.4 33.8 GO:0070064 proline-rich region binding(GO:0070064)
2.2 33.0 GO:0048407 platelet-derived growth factor binding(GO:0048407)
8.1 32.4 GO:0050700 CARD domain binding(GO:0050700)
6.4 32.1 GO:0032027 myosin light chain binding(GO:0032027)
0.4 31.6 GO:0048306 calcium-dependent protein binding(GO:0048306)
5.8 29.2 GO:0071253 connexin binding(GO:0071253)
1.9 26.4 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.3 23.1 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.5 21.8 GO:0035496 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980) O antigen polymerase activity(GO:0008755) lipopolysaccharide-1,6-galactosyltransferase activity(GO:0008921) cellulose synthase activity(GO:0016759) 9-phenanthrol UDP-glucuronosyltransferase activity(GO:0018715) 1-phenanthrol glycosyltransferase activity(GO:0018716) 9-phenanthrol glycosyltransferase activity(GO:0018717) 1,2-dihydroxy-phenanthrene glycosyltransferase activity(GO:0018718) phenanthrol glycosyltransferase activity(GO:0019112) alpha-1,2-galactosyltransferase activity(GO:0031278) dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0033556) endogalactosaminidase activity(GO:0033931) lipopolysaccharide-1,5-galactosyltransferase activity(GO:0035496) dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0042283) inositol phosphoceramide synthase activity(GO:0045140) alpha-(1->3)-fucosyltransferase activity(GO:0046920) indole-3-butyrate beta-glucosyltransferase activity(GO:0052638) salicylic acid glucosyltransferase (ester-forming) activity(GO:0052639) salicylic acid glucosyltransferase (glucoside-forming) activity(GO:0052640) benzoic acid glucosyltransferase activity(GO:0052641) chondroitin hydrolase activity(GO:0052757) dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity(GO:0052824) cytokinin 9-beta-glucosyltransferase activity(GO:0080062)
1.8 21.5 GO:0045294 alpha-catenin binding(GO:0045294)
1.0 20.9 GO:0004602 glutathione peroxidase activity(GO:0004602)
2.0 19.8 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1 18.9 GO:0003735 structural constituent of ribosome(GO:0003735)
2.3 18.1 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)