Motif ID: Scrt2

Z-value: 1.462


Transcription factors associated with Scrt2:

Gene SymbolEntrez IDGene Name
Scrt2 ENSMUSG00000060257.2 Scrt2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Scrt2mm10_v2_chr2_+_152081529_152081624-0.781.5e-15Click!


Activity profile for motif Scrt2.

activity profile for motif Scrt2


Sorted Z-values histogram for motif Scrt2

Sorted Z-values for motif Scrt2



Network of associatons between targets according to the STRING database.



First level regulatory network of Scrt2

PNG image of the network

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Top targets:


Showing 1 to 20 of 106 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_34649987 25.521 ENSMUST00000099151.2
Sox2
SRY-box containing gene 2
chr10_+_56377300 21.800 ENSMUST00000068581.7
Gja1
gap junction protein, alpha 1
chr7_-_25250720 18.678 ENSMUST00000116343.2
ENSMUST00000045847.8
Erf

Ets2 repressor factor

chr11_-_55419898 18.502 ENSMUST00000108858.1
ENSMUST00000141530.1
Sparc

secreted acidic cysteine rich glycoprotein

chr6_-_53820764 18.251 ENSMUST00000127748.2
Tril
TLR4 interactor with leucine-rich repeats
chr2_-_164443177 16.893 ENSMUST00000017153.3
Sdc4
syndecan 4
chr15_-_98004634 16.567 ENSMUST00000131560.1
ENSMUST00000088355.5
Col2a1

collagen, type II, alpha 1

chr17_-_25570678 15.538 ENSMUST00000025003.3
ENSMUST00000173447.1
Sox8

SRY-box containing gene 8

chr2_+_31950257 14.824 ENSMUST00000001920.7
Aif1l
allograft inflammatory factor 1-like
chr6_-_135168162 14.622 ENSMUST00000045855.7
Hebp1
heme binding protein 1
chr16_+_16213318 13.962 ENSMUST00000162150.1
ENSMUST00000161342.1
ENSMUST00000039408.2
Pkp2


plakophilin 2


chr2_+_91257323 13.513 ENSMUST00000111349.2
ENSMUST00000131711.1
Pacsin3

protein kinase C and casein kinase substrate in neurons 3

chr3_-_108840477 12.038 ENSMUST00000106596.3
ENSMUST00000102621.4
Stxbp3a

syntaxin binding protein 3A

chr1_-_133424377 11.691 ENSMUST00000153799.1
Sox13
SRY-box containing gene 13
chr2_+_91256813 11.383 ENSMUST00000144394.1
ENSMUST00000028694.5
ENSMUST00000168916.1
ENSMUST00000156919.1
Pacsin3



protein kinase C and casein kinase substrate in neurons 3



chr13_-_81633119 11.001 ENSMUST00000126444.1
ENSMUST00000128585.1
ENSMUST00000146749.1
ENSMUST00000095585.4
Gpr98



G protein-coupled receptor 98



chr8_+_31187317 10.820 ENSMUST00000066173.5
ENSMUST00000161788.1
ENSMUST00000110527.2
ENSMUST00000161502.1
Fut10



fucosyltransferase 10



chr11_+_53770458 10.702 ENSMUST00000138913.1
ENSMUST00000123376.1
ENSMUST00000019043.6
ENSMUST00000133291.1
Irf1



interferon regulatory factor 1



chr7_-_30973399 10.481 ENSMUST00000098553.4
ENSMUST00000147431.1
Lsr

lipolysis stimulated lipoprotein receptor

chr3_-_53657339 10.400 ENSMUST00000091137.4
Frem2
Fras1 related extracellular matrix protein 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 65 entries
Log-likelihood per target Total log-likelihoodTermDescription
9.8 29.3 GO:1904274 tricellular tight junction assembly(GO:1904274)
3.6 25.5 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
1.1 24.9 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
7.3 21.8 GO:0003104 positive regulation of glomerular filtration(GO:0003104) cell communication by chemical coupling(GO:0010643)
3.7 18.7 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.4 18.6 GO:0042168 heme metabolic process(GO:0042168)
0.5 18.5 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.9 18.3 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
3.4 16.9 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
1.5 16.6 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
5.2 15.5 GO:0072034 renal vesicle induction(GO:0072034)
0.5 14.9 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
4.7 14.0 GO:0086069 desmosome assembly(GO:0002159) adherens junction maintenance(GO:0034334) intermediate filament bundle assembly(GO:0045110) maintenance of organ identity(GO:0048496) bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.9 11.7 GO:0046643 regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.5 10.9 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.7 10.8 GO:0036065 fucosylation(GO:0036065)
3.6 10.7 GO:2000564 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124) CD8-positive, alpha-beta T cell proliferation(GO:0035740) negative regulation of regulatory T cell differentiation(GO:0045590) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.3 9.4 GO:0050873 brown fat cell differentiation(GO:0050873)
0.4 9.2 GO:0008105 asymmetric protein localization(GO:0008105)
0.0 9.1 GO:0048839 inner ear development(GO:0048839)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 39 entries
Log-likelihood per target Total log-likelihoodTermDescription
4.9 29.3 GO:0061689 tricellular tight junction(GO:0061689)
0.2 26.6 GO:0044798 nuclear transcription factor complex(GO:0044798)
2.0 21.8 GO:0005916 fascia adherens(GO:0005916)
0.6 21.4 GO:0043034 costamere(GO:0043034)
1.9 21.3 GO:0030057 desmosome(GO:0030057)
0.1 20.3 GO:0005802 trans-Golgi network(GO:0005802)
4.6 18.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
3.0 18.3 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.2 17.9 GO:0005604 basement membrane(GO:0005604)
0.1 17.9 GO:0098793 presynapse(GO:0098793)
1.3 16.6 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 14.9 GO:0005925 focal adhesion(GO:0005925)
0.1 14.5 GO:0031012 extracellular matrix(GO:0031012)
0.2 10.8 GO:0030667 secretory granule membrane(GO:0030667)
0.0 10.7 GO:0005667 transcription factor complex(GO:0005667)
0.1 8.8 GO:0005776 autophagosome(GO:0005776)
0.2 7.9 GO:0005581 collagen trimer(GO:0005581)
0.0 7.9 GO:0000139 Golgi membrane(GO:0000139)
0.8 6.6 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.4 6.6 GO:0042555 MCM complex(GO:0042555)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 58 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.6 31.3 GO:0035198 miRNA binding(GO:0035198)
0.4 29.9 GO:0005518 collagen binding(GO:0005518)
2.0 29.3 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
1.7 24.9 GO:0019855 calcium channel inhibitor activity(GO:0019855)
4.4 21.8 GO:0071253 connexin binding(GO:0071253)
0.3 19.9 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 18.7 GO:0003714 transcription corepressor activity(GO:0003714)
1.3 18.3 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.1 18.2 GO:0003924 GTPase activity(GO:0003924)
0.1 17.4 GO:0051015 actin filament binding(GO:0051015)
0.0 17.4 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
3.4 16.9 GO:0070053 thrombospondin receptor activity(GO:0070053)
1.1 16.6 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.2 15.5 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.2 14.6 GO:0020037 heme binding(GO:0020037)
1.2 14.0 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 10.9 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
1.1 8.8 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.7 8.0 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 7.8 GO:0035496 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980) O antigen polymerase activity(GO:0008755) lipopolysaccharide-1,6-galactosyltransferase activity(GO:0008921) cellulose synthase activity(GO:0016759) 9-phenanthrol UDP-glucuronosyltransferase activity(GO:0018715) 1-phenanthrol glycosyltransferase activity(GO:0018716) 9-phenanthrol glycosyltransferase activity(GO:0018717) 1,2-dihydroxy-phenanthrene glycosyltransferase activity(GO:0018718) phenanthrol glycosyltransferase activity(GO:0019112) alpha-1,2-galactosyltransferase activity(GO:0031278) dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0033556) endogalactosaminidase activity(GO:0033931) lipopolysaccharide-1,5-galactosyltransferase activity(GO:0035496) dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0042283) inositol phosphoceramide synthase activity(GO:0045140) alpha-(1->3)-fucosyltransferase activity(GO:0046920) indole-3-butyrate beta-glucosyltransferase activity(GO:0052638) salicylic acid glucosyltransferase (ester-forming) activity(GO:0052639) salicylic acid glucosyltransferase (glucoside-forming) activity(GO:0052640) benzoic acid glucosyltransferase activity(GO:0052641) chondroitin hydrolase activity(GO:0052757) dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity(GO:0052824) cytokinin 9-beta-glucosyltransferase activity(GO:0080062)