Motif ID: Smad4
Z-value: 1.387

Transcription factors associated with Smad4:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Smad4 | ENSMUSG00000024515.7 | Smad4 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Smad4 | mm10_v2_chr18_-_73703739_73703806 | 0.13 | 2.9e-01 | Click! |
Top targets:
Showing 1 to 20 of 176 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 95 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
4.0 | 27.9 | GO:0009449 | gamma-aminobutyric acid biosynthetic process(GO:0009449) |
1.1 | 22.2 | GO:0030903 | notochord development(GO:0030903) |
1.1 | 21.8 | GO:0045653 | negative regulation of megakaryocyte differentiation(GO:0045653) |
3.7 | 18.6 | GO:0021764 | amygdala development(GO:0021764) |
0.7 | 15.9 | GO:0032967 | positive regulation of collagen biosynthetic process(GO:0032967) |
3.1 | 15.6 | GO:0014719 | skeletal muscle satellite cell activation(GO:0014719) |
2.6 | 13.0 | GO:0030951 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) |
4.2 | 12.6 | GO:0046122 | purine deoxyribonucleoside metabolic process(GO:0046122) |
2.5 | 12.4 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) |
4.0 | 11.9 | GO:0015889 | cobalamin transport(GO:0015889) |
0.3 | 10.1 | GO:0048384 | retinoic acid receptor signaling pathway(GO:0048384) |
1.7 | 8.6 | GO:0060754 | positive regulation of mast cell chemotaxis(GO:0060754) |
2.1 | 8.4 | GO:2000313 | fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313) |
0.5 | 7.9 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
0.4 | 7.7 | GO:0050434 | positive regulation of viral transcription(GO:0050434) |
0.3 | 7.7 | GO:0001921 | positive regulation of receptor recycling(GO:0001921) |
0.0 | 7.7 | GO:0016055 | Wnt signaling pathway(GO:0016055) cell-cell signaling by wnt(GO:0198738) |
2.5 | 7.6 | GO:1902460 | regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462) |
0.1 | 7.6 | GO:0002066 | columnar/cuboidal epithelial cell development(GO:0002066) |
0.8 | 7.4 | GO:0035090 | maintenance of apical/basal cell polarity(GO:0035090) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 52 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 41.4 | GO:0005667 | transcription factor complex(GO:0005667) |
0.9 | 27.9 | GO:0060077 | inhibitory synapse(GO:0060077) |
0.3 | 26.5 | GO:0000786 | nucleosome(GO:0000786) |
0.0 | 21.7 | GO:0005874 | microtubule(GO:0005874) |
5.3 | 15.9 | GO:0038045 | large latent transforming growth factor-beta complex(GO:0038045) |
0.6 | 13.0 | GO:0001891 | phagocytic cup(GO:0001891) |
0.2 | 12.4 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
0.0 | 11.5 | GO:0005783 | endoplasmic reticulum(GO:0005783) |
0.3 | 10.7 | GO:0035371 | microtubule plus-end(GO:0035371) |
0.2 | 10.4 | GO:0005581 | collagen trimer(GO:0005581) |
0.0 | 9.5 | GO:0005730 | nucleolus(GO:0005730) |
0.0 | 8.4 | GO:0005802 | trans-Golgi network(GO:0005802) |
0.7 | 7.4 | GO:0000137 | Golgi cis cisterna(GO:0000137) |
0.5 | 7.0 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
0.3 | 6.6 | GO:0008305 | integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636) |
0.1 | 5.7 | GO:0005719 | nuclear euchromatin(GO:0005719) |
0.0 | 4.3 | GO:0005938 | cell cortex(GO:0005938) |
0.5 | 3.8 | GO:0070652 | HAUS complex(GO:0070652) |
0.2 | 3.6 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
0.3 | 3.5 | GO:1902710 | GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 63 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
4.0 | 27.9 | GO:0004351 | glutamate decarboxylase activity(GO:0004351) |
0.2 | 25.4 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
0.1 | 21.8 | GO:0042393 | histone binding(GO:0042393) |
0.3 | 18.6 | GO:0003707 | steroid hormone receptor activity(GO:0003707) |
4.1 | 16.3 | GO:0050436 | microfibril binding(GO:0050436) |
4.2 | 12.6 | GO:0004731 | purine-nucleoside phosphorylase activity(GO:0004731) |
1.0 | 12.4 | GO:0045294 | alpha-catenin binding(GO:0045294) |
1.7 | 11.9 | GO:0031419 | cobalamin binding(GO:0031419) |
0.4 | 11.0 | GO:0008432 | JUN kinase binding(GO:0008432) |
0.0 | 11.0 | GO:0003713 | transcription coactivator activity(GO:0003713) |
0.7 | 10.7 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
0.6 | 10.1 | GO:0003708 | retinoic acid receptor activity(GO:0003708) |
0.3 | 9.7 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
0.2 | 8.5 | GO:0070888 | E-box binding(GO:0070888) |
0.1 | 8.3 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
0.7 | 7.7 | GO:0030957 | Tat protein binding(GO:0030957) |
0.5 | 7.7 | GO:0031702 | type 1 angiotensin receptor binding(GO:0031702) |
0.0 | 7.7 | GO:0005096 | GTPase activator activity(GO:0005096) |
0.4 | 7.6 | GO:0050431 | transforming growth factor beta binding(GO:0050431) |
0.0 | 7.6 | GO:0051015 | actin filament binding(GO:0051015) |