Motif ID: Sox11

Z-value: 0.397


Transcription factors associated with Sox11:

Gene SymbolEntrez IDGene Name
Sox11 ENSMUSG00000063632.5 Sox11

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox11mm10_v2_chr12_-_27342696_273427260.762.5e-14Click!


Activity profile for motif Sox11.

activity profile for motif Sox11


Sorted Z-values histogram for motif Sox11

Sorted Z-values for motif Sox11



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox11

PNG image of the network

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Top targets:


Showing 1 to 20 of 72 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_-_16378231 2.898 ENSMUST00000082170.5
 Fat3
FAT tumor suppressor homolog 3 (Drosophila)
chr5_+_14514918 2.226 ENSMUST00000030691.10
ENSMUST00000182407.1
 Pclo

piccolo (presynaptic cytomatrix protein)

chr2_-_79456750 2.218 ENSMUST00000041099.4
 Neurod1
neurogenic differentiation 1
chr5_-_131616599 1.745 ENSMUST00000161804.1
 Auts2
autism susceptibility candidate 2
chr9_+_89909775 1.408 ENSMUST00000034912.4
ENSMUST00000034909.4
 Rasgrf1

RAS protein-specific guanine nucleotide-releasing factor 1

chr13_-_99516537 1.380 ENSMUST00000064762.4
 Map1b
microtubule-associated protein 1B
chr11_+_69364010 1.195 ENSMUST00000166700.1
 Gm17305
predicted gene, 17305
chrX_+_85574018 1.164 ENSMUST00000048250.3
ENSMUST00000137438.1
ENSMUST00000146063.1
 Tab3


TGF-beta activated kinase 1/MAP3K7 binding protein 3


chr11_+_24080664 1.118 ENSMUST00000118955.1
 Bcl11a
B cell CLL/lymphoma 11A (zinc finger protein)
chr16_-_50330987 1.030 ENSMUST00000114488.1
 Bbx
bobby sox homolog (Drosophila)
chr8_-_34965631 0.994 ENSMUST00000033929.4
 Tnks
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr9_+_107888129 0.983 ENSMUST00000035202.2
 Mon1a
MON1 homolog A (yeast)
chrX_+_166344692 0.869 ENSMUST00000112223.1
ENSMUST00000112224.1
ENSMUST00000112229.2
ENSMUST00000112228.1
ENSMUST00000112227.2
ENSMUST00000112226.2
 Gpm6b





glycoprotein m6b





chr6_-_60829826 0.868 ENSMUST00000163779.1
 Snca
synuclein, alpha
chr1_+_82233112 0.794 ENSMUST00000023262.5
 Gm9747
predicted gene 9747
chr17_-_29007925 0.735 ENSMUST00000009138.5
ENSMUST00000119274.1
 Stk38

serine/threonine kinase 38

chr4_-_44072578 0.713 ENSMUST00000173383.1
 Gne
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr16_+_8830093 0.704 ENSMUST00000023150.5
 1810013L24Rik
RIKEN cDNA 1810013L24 gene
chr14_-_52213379 0.655 ENSMUST00000140603.1
 Chd8
chromodomain helicase DNA binding protein 8
chr11_+_4873951 0.626 ENSMUST00000038570.2
 Nipsnap1
4-nitrophenylphosphatase domain and non-neuronal SNAP25-like protein homolog 1 (C. elegans)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.9 GO:0010842 retina layer formation(GO:0010842)
0.6 2.2 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.4 2.2 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.6 1.7 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.2 1.7 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 1.4 GO:0061162 establishment of monopolar cell polarity(GO:0061162)
0.1 1.4 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.1 1.1 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.3 1.0 GO:1904742 protein poly-ADP-ribosylation(GO:0070212) regulation of telomeric DNA binding(GO:1904742)
0.0 1.0 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.1 0.7 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.7 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.2 0.6 GO:0032696 negative regulation of interleukin-13 production(GO:0032696) negative regulation of interleukin-10 secretion(GO:2001180)
0.1 0.6 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.6 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.6 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.2 0.5 GO:2000409 positive regulation of T cell extravasation(GO:2000409)
0.1 0.4 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.4 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.4 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)

Gene overrepresentation in cellular_component category:

Showing 1 to 16 of 16 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 2.2 GO:0044316 cone cell pedicle(GO:0044316)
0.0 2.2 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 1.4 GO:0043196 varicosity(GO:0043196)
0.1 1.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 1.0 GO:0005643 nuclear pore(GO:0005643)
0.2 0.9 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.7 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.7 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.6 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.5 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.5 GO:0016592 mediator complex(GO:0016592)
0.0 0.4 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.4 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 0.3 GO:0072487 MSL complex(GO:0072487)
0.0 0.2 GO:0051286 cell tip(GO:0051286)
0.0 0.1 GO:0097361 CIA complex(GO:0097361)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 20 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.2 GO:0005522 profilin binding(GO:0005522)
0.0 2.2 GO:0070888 E-box binding(GO:0070888)
0.2 1.4 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.0 1.4 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 1.0 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 1.0 GO:0042165 neurotransmitter binding(GO:0042165)
0.1 0.9 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 0.7 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761)
0.0 0.7 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.7 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.6 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.6 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.6 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.4 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 0.3 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.3 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.2 GO:0032052 bile acid binding(GO:0032052)
0.0 0.2 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.1 GO:0004984 olfactory receptor activity(GO:0004984)