Motif ID: Sox13

Z-value: 0.329


Transcription factors associated with Sox13:

Gene SymbolEntrez IDGene Name
Sox13 ENSMUSG00000070643.5 Sox13

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox13mm10_v2_chr1_-_133424377_1334244040.381.1e-03Click!


Activity profile for motif Sox13.

activity profile for motif Sox13


Sorted Z-values histogram for motif Sox13

Sorted Z-values for motif Sox13



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox13

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_84773381 2.770 ENSMUST00000109764.1
Nfix
nuclear factor I/X
chr3_+_34649987 2.454 ENSMUST00000099151.2
Sox2
SRY-box containing gene 2
chr2_+_25180737 2.328 ENSMUST00000104999.2
Nrarp
Notch-regulated ankyrin repeat protein
chr1_+_135729147 1.401 ENSMUST00000027677.7
Csrp1
cysteine and glycine-rich protein 1
chr2_-_36104060 1.179 ENSMUST00000112961.3
ENSMUST00000112966.3
Lhx6

LIM homeobox protein 6

chr7_+_96210107 0.949 ENSMUST00000138760.1
Tenm4
teneurin transmembrane protein 4
chr8_-_11008458 0.948 ENSMUST00000040514.6
Irs2
insulin receptor substrate 2
chr1_+_19103022 0.917 ENSMUST00000037294.7
Tfap2d
transcription factor AP-2, delta
chr4_-_58499398 0.900 ENSMUST00000107570.1
Lpar1
lysophosphatidic acid receptor 1
chr18_+_69593361 0.879 ENSMUST00000114978.2
ENSMUST00000114977.1
Tcf4

transcription factor 4

chr7_-_121035096 0.561 ENSMUST00000065740.2
Gm9905
predicted gene 9905
chr7_-_132813095 0.540 ENSMUST00000106165.1
Fam53b
family with sequence similarity 53, member B
chr19_-_19001099 0.510 ENSMUST00000040153.8
ENSMUST00000112828.1
Rorb

RAR-related orphan receptor beta

chr15_-_50890396 0.507 ENSMUST00000185183.1
Trps1
trichorhinophalangeal syndrome I (human)
chr3_-_141982224 0.493 ENSMUST00000029948.8
Bmpr1b
bone morphogenetic protein receptor, type 1B
chr12_+_24708984 0.431 ENSMUST00000154588.1
Rrm2
ribonucleotide reductase M2
chr10_+_53596936 0.404 ENSMUST00000020004.6
Asf1a
ASF1 anti-silencing function 1 homolog A (S. cerevisiae)
chr3_+_60501252 0.394 ENSMUST00000099087.2
Mbnl1
muscleblind-like 1 (Drosophila)
chr1_+_39900883 0.356 ENSMUST00000163854.2
ENSMUST00000168431.1
Map4k4

mitogen-activated protein kinase kinase kinase kinase 4

chr14_+_79515618 0.315 ENSMUST00000110835.1
Elf1
E74-like factor 1
chr7_-_105787567 0.311 ENSMUST00000144189.1
Dchs1
dachsous 1 (Drosophila)
chr15_-_91049823 0.302 ENSMUST00000088614.5
ENSMUST00000100304.4
ENSMUST00000067205.8
ENSMUST00000109288.2
ENSMUST00000109287.2
Kif21a




kinesin family member 21A




chr13_-_66851513 0.278 ENSMUST00000169322.1
Gm17404
predicted gene, 17404
chr10_-_53647080 0.237 ENSMUST00000169866.1
Fam184a
family with sequence similarity 184, member A
chr19_-_7241216 0.233 ENSMUST00000025675.9
Naa40
N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)
chr1_-_93101825 0.233 ENSMUST00000112958.2
Kif1a
kinesin family member 1A
chr4_+_103143052 0.195 ENSMUST00000106855.1
Mier1
mesoderm induction early response 1 homolog (Xenopus laevis
chr13_-_66852017 0.147 ENSMUST00000059329.6
Gm17449
predicted gene, 17449
chr5_-_8367982 0.140 ENSMUST00000088761.4
ENSMUST00000115386.1
ENSMUST00000050166.7
ENSMUST00000046838.7
ENSMUST00000115388.2
ENSMUST00000088744.5
ENSMUST00000115385.1
Adam22






a disintegrin and metallopeptidase domain 22






chr12_+_36314160 0.140 ENSMUST00000041407.5
Sostdc1
sclerostin domain containing 1
chr9_-_75597643 0.050 ENSMUST00000164100.1
Tmod2
tropomodulin 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.5 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.2 0.9 GO:0032289 central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912)
0.2 0.9 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.2 2.3 GO:0014807 regulation of somitogenesis(GO:0014807)
0.2 2.8 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.2 1.2 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 0.5 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1 0.9 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.1 0.9 GO:0042118 endothelial cell activation(GO:0042118)
0.1 0.5 GO:0046549 retinal cone cell development(GO:0046549)
0.1 0.3 GO:0003192 mitral valve formation(GO:0003192) cell migration involved in endocardial cushion formation(GO:0003273) condensed mesenchymal cell proliferation(GO:0072137)
0.0 0.4 GO:0009186 deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.0 0.4 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.1 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.0 0.5 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.3 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 1.4 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.9 GO:0030901 midbrain development(GO:0030901)
0.0 0.2 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.0 0.4 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-dependent nucleosome organization(GO:0034723) DNA replication-independent nucleosome organization(GO:0034724)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0 2.5 GO:0044798 nuclear transcription factor complex(GO:0044798)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2 0.5 GO:0008502 melatonin receptor activity(GO:0008502)
0.2 0.9 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.4 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 2.5 GO:0035198 miRNA binding(GO:0035198)
0.1 0.4 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.4 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 0.5 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.9 GO:0071889 14-3-3 protein binding(GO:0071889)