Motif ID: Sox14

Z-value: 1.211


Transcription factors associated with Sox14:

Gene SymbolEntrez IDGene Name
Sox14 ENSMUSG00000053747.8 Sox14

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox14mm10_v2_chr9_-_99876147_99876193-0.343.7e-03Click!


Activity profile for motif Sox14.

activity profile for motif Sox14


Sorted Z-values histogram for motif Sox14

Sorted Z-values for motif Sox14



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox14

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_-_14523178 19.254 ENSMUST00000110516.2
 Hecw1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr11_+_67586520 16.363 ENSMUST00000108682.2
 Gas7
growth arrest specific 7
chr11_+_67586675 14.204 ENSMUST00000108680.1
 Gas7
growth arrest specific 7
chr17_-_79355082 11.559 ENSMUST00000068958.7
 Cdc42ep3
CDC42 effector protein (Rho GTPase binding) 3
chr11_+_24076529 11.374 ENSMUST00000148087.1
 Gm12063
predicted gene 12063
chr7_-_19166119 9.441 ENSMUST00000094790.3
 Gipr
gastric inhibitory polypeptide receptor
chr18_-_43393346 9.349 ENSMUST00000025379.7
 Dpysl3
dihydropyrimidinase-like 3
chr18_-_43059418 9.242 ENSMUST00000025377.7
 Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chrX_-_167209149 9.010 ENSMUST00000112176.1
 Tmsb4x
thymosin, beta 4, X chromosome
chr12_+_31265279 8.665 ENSMUST00000002979.8
ENSMUST00000170495.1
 Lamb1

laminin B1

chr2_-_85196697 8.525 ENSMUST00000099930.2
ENSMUST00000111601.1
 Lrrc55

leucine rich repeat containing 55

chr7_+_96210107 8.478 ENSMUST00000138760.1
 Tenm4
teneurin transmembrane protein 4
chr1_-_12991109 8.438 ENSMUST00000115403.2
ENSMUST00000115402.1
 Slco5a1

solute carrier organic anion transporter family, member 5A1

chr8_-_105289465 8.236 ENSMUST00000171788.1
ENSMUST00000014981.6
 4931428F04Rik

RIKEN cDNA 4931428F04 gene

chr5_-_38159457 8.193 ENSMUST00000031009.4
 Nsg1
neuron specific gene family member 1
chr16_+_17144600 8.142 ENSMUST00000115702.1
 Ydjc
YdjC homolog (bacterial)
chr4_+_13751297 8.136 ENSMUST00000105566.2
 Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr8_-_84773381 8.134 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr3_+_55461758 7.959 ENSMUST00000070418.4
 Dclk1
doublecortin-like kinase 1
chr12_+_31265234 7.703 ENSMUST00000169088.1
 Lamb1
laminin B1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 143 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 29.9 GO:0051017 actin filament bundle assembly(GO:0051017)
0.1 19.3 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
4.1 16.4 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.7 16.4 GO:0008340 determination of adult lifespan(GO:0008340)
4.6 13.7 GO:0042560 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.2 13.3 GO:0032410 negative regulation of transporter activity(GO:0032410)
1.0 11.6 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.3 9.4 GO:0022401 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401)
1.3 9.2 GO:0034047 regulation of protein phosphatase type 2A activity(GO:0034047)
0.1 9.2 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.8 9.0 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.6 8.8 GO:0051764 actin crosslink formation(GO:0051764)
2.1 8.5 GO:0032289 central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912)
0.8 8.4 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.6 8.4 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.4 8.2 GO:0048268 clathrin coat assembly(GO:0048268)
0.6 8.1 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.2 8.1 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.2 8.0 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.7 7.7 GO:2001256 regulation of store-operated calcium entry(GO:2001256)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 62 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 33.4 GO:0005884 actin filament(GO:0005884)
0.1 23.0 GO:0015629 actin cytoskeleton(GO:0015629)
4.1 16.4 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.1 11.8 GO:0001726 ruffle(GO:0001726)
0.0 11.3 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.1 10.2 GO:0043204 perikaryon(GO:0043204)
0.1 10.2 GO:0016607 nuclear speck(GO:0016607)
0.2 9.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.5 9.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 8.8 GO:0042641 actomyosin(GO:0042641)
1.4 8.4 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.1 8.2 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 8.2 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.2 7.7 GO:0043034 costamere(GO:0043034)
0.3 7.6 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.3 7.1 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.5 6.6 GO:0070938 contractile ring(GO:0070938)
0.6 6.5 GO:1990909 Wnt signalosome(GO:1990909)
0.1 6.4 GO:0030027 lamellipodium(GO:0030027)
0.5 5.9 GO:0031258 catenin complex(GO:0016342) lamellipodium membrane(GO:0031258)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 106 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 38.0 GO:0043774 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738)
0.2 29.9 GO:0051015 actin filament binding(GO:0051015)
2.0 16.4 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 14.3 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.8 13.8 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
4.6 13.7 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.5 11.6 GO:0017049 GTP-Rho binding(GO:0017049)
0.3 10.4 GO:0051721 protein phosphatase 2A binding(GO:0051721)
2.0 10.0 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.3 9.4 GO:0017046 peptide hormone binding(GO:0017046)
2.3 9.3 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.7 9.2 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.3 9.0 GO:0003785 actin monomer binding(GO:0003785)
0.2 8.6 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.8 8.4 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
1.4 8.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 8.2 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.4 8.1 GO:0043747 protein-N-terminal asparagine amidohydrolase activity(GO:0008418) UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity(GO:0008759) iprodione amidohydrolase activity(GO:0018748) (3,5-dichlorophenylurea)acetate amidohydrolase activity(GO:0018749) 4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity(GO:0034571) didemethylisoproturon amidohydrolase activity(GO:0034573) N-isopropylacetanilide amidohydrolase activity(GO:0034576) N-cyclohexylformamide amidohydrolase activity(GO:0034781) isonicotinic acid hydrazide hydrolase activity(GO:0034876) cis-aconitamide amidase activity(GO:0034882) gamma-N-formylaminovinylacetate hydrolase activity(GO:0034885) N2-acetyl-L-lysine deacetylase activity(GO:0043747) O-succinylbenzoate synthase activity(GO:0043748) indoleacetamide hydrolase activity(GO:0043864) N-acetylcitrulline deacetylase activity(GO:0043909) N-acetylgalactosamine-6-phosphate deacetylase activity(GO:0047419) diacetylchitobiose deacetylase activity(GO:0052773) chitooligosaccharide deacetylase activity(GO:0052790)
1.1 7.7 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
1.5 7.6 GO:0052833 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)