Motif ID: Sox3_Sox10
Z-value: 2.414
Transcription factors associated with Sox3_Sox10:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Sox10 | ENSMUSG00000033006.9 | Sox10 |
Sox3 | ENSMUSG00000045179.8 | Sox3 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Sox3 | mm10_v2_chrX_-_60893430_60893440 | -0.68 | 1.1e-10 | Click! |
Sox10 | mm10_v2_chr15_-_79164477_79164496 | -0.68 | 1.3e-10 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
17.4 | 52.3 | GO:2000297 | negative regulation of synapse maturation(GO:2000297) |
12.0 | 36.1 | GO:0042560 | 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560) |
7.7 | 7.7 | GO:0010643 | cell communication by chemical coupling(GO:0010643) |
7.4 | 29.6 | GO:1904529 | regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616) |
7.1 | 35.6 | GO:0046684 | response to pyrethroid(GO:0046684) |
7.1 | 28.5 | GO:2000795 | negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795) |
6.9 | 20.7 | GO:2000620 | positive regulation of histone H4-K16 acetylation(GO:2000620) |
6.5 | 6.5 | GO:1904339 | negative regulation of dopaminergic neuron differentiation(GO:1904339) |
6.3 | 25.3 | GO:0032289 | central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912) |
6.2 | 24.7 | GO:0021764 | amygdala development(GO:0021764) |
6.2 | 18.5 | GO:0030827 | negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283) |
6.1 | 18.3 | GO:0014877 | response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) |
5.8 | 133.3 | GO:0021819 | layer formation in cerebral cortex(GO:0021819) |
5.7 | 17.2 | GO:0033634 | positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) |
5.4 | 87.0 | GO:1900454 | positive regulation of long term synaptic depression(GO:1900454) |
5.4 | 27.1 | GO:2001025 | positive regulation of response to drug(GO:2001025) |
5.4 | 16.2 | GO:2000344 | positive regulation of acrosome reaction(GO:2000344) |
5.2 | 20.7 | GO:1903587 | regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587) |
5.0 | 60.6 | GO:0031274 | positive regulation of pseudopodium assembly(GO:0031274) |
4.9 | 34.6 | GO:0034047 | regulation of protein phosphatase type 2A activity(GO:0034047) |
4.8 | 19.3 | GO:0046898 | response to cycloheximide(GO:0046898) |
4.6 | 23.2 | GO:0043314 | negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313) |
4.5 | 17.9 | GO:0021812 | neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812) |
4.5 | 17.8 | GO:2001016 | positive regulation of skeletal muscle cell differentiation(GO:2001016) |
3.9 | 11.7 | GO:0038095 | positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095) |
3.7 | 11.2 | GO:1900039 | positive regulation of cellular response to hypoxia(GO:1900039) |
3.7 | 22.3 | GO:0006172 | ADP biosynthetic process(GO:0006172) |
3.6 | 21.8 | GO:0060371 | regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371) |
3.6 | 14.4 | GO:0001922 | B-1 B cell homeostasis(GO:0001922) |
3.6 | 3.6 | GO:2001180 | negative regulation of interleukin-10 secretion(GO:2001180) |
3.6 | 10.7 | GO:0032241 | positive regulation of nucleobase-containing compound transport(GO:0032241) |
3.4 | 27.5 | GO:0005513 | detection of calcium ion(GO:0005513) |
3.4 | 10.3 | GO:0021649 | vestibulocochlear nerve morphogenesis(GO:0021648) vestibulocochlear nerve structural organization(GO:0021649) ganglion morphogenesis(GO:0061552) dorsal root ganglion morphogenesis(GO:1904835) dorsal root ganglion development(GO:1990791) |
3.4 | 6.8 | GO:2000017 | positive regulation of determination of dorsal identity(GO:2000017) |
3.3 | 32.5 | GO:0071635 | negative regulation of transforming growth factor beta production(GO:0071635) |
3.2 | 35.4 | GO:0086018 | SA node cell action potential(GO:0086015) SA node cell to atrial cardiac muscle cell signalling(GO:0086018) SA node cell to atrial cardiac muscle cell communication(GO:0086070) |
3.2 | 9.5 | GO:0070649 | formin-nucleated actin cable assembly(GO:0070649) |
3.2 | 12.7 | GO:0003105 | negative regulation of glomerular filtration(GO:0003105) |
3.1 | 12.6 | GO:0036072 | intramembranous ossification(GO:0001957) direct ossification(GO:0036072) |
3.0 | 9.1 | GO:0070428 | regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428) |
2.8 | 8.5 | GO:0021546 | rhombomere development(GO:0021546) |
2.8 | 11.3 | GO:1900740 | regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740) |
2.7 | 8.1 | GO:0061030 | epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030) |
2.7 | 8.0 | GO:0032650 | regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730) interleukin-1 alpha secretion(GO:0050703) |
2.7 | 10.7 | GO:0032512 | regulation of protein phosphatase type 2B activity(GO:0032512) positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316) |
2.6 | 10.5 | GO:1990743 | protein sialylation(GO:1990743) |
2.6 | 18.4 | GO:0042518 | negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518) |
2.6 | 20.9 | GO:0006003 | fructose 2,6-bisphosphate metabolic process(GO:0006003) |
2.6 | 23.3 | GO:0035887 | aortic smooth muscle cell differentiation(GO:0035887) |
2.5 | 20.3 | GO:0051152 | positive regulation of smooth muscle cell differentiation(GO:0051152) |
2.5 | 7.5 | GO:0003357 | noradrenergic neuron differentiation(GO:0003357) |
2.4 | 33.6 | GO:0021684 | cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) |
2.4 | 23.9 | GO:0046543 | development of secondary female sexual characteristics(GO:0046543) |
2.4 | 14.2 | GO:0000160 | phosphorelay signal transduction system(GO:0000160) |
2.4 | 37.6 | GO:0014049 | positive regulation of glutamate secretion(GO:0014049) |
2.3 | 11.4 | GO:0030259 | lipid glycosylation(GO:0030259) |
2.2 | 15.6 | GO:0045200 | establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) |
2.2 | 30.5 | GO:0007194 | negative regulation of adenylate cyclase activity(GO:0007194) |
2.2 | 6.5 | GO:2000616 | negative regulation of histone H3-K9 acetylation(GO:2000616) |
2.1 | 4.2 | GO:0050883 | musculoskeletal movement, spinal reflex action(GO:0050883) |
2.0 | 6.1 | GO:0003245 | cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245) |
2.0 | 6.0 | GO:0071929 | alpha-tubulin acetylation(GO:0071929) |
2.0 | 5.9 | GO:0061588 | calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591) |
1.9 | 13.5 | GO:0051611 | negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
1.9 | 17.3 | GO:0009312 | oligosaccharide biosynthetic process(GO:0009312) |
1.8 | 24.0 | GO:1901898 | negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898) |
1.8 | 36.7 | GO:0006054 | N-acetylneuraminate metabolic process(GO:0006054) |
1.8 | 1.8 | GO:0002034 | angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001998) regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072) |
1.8 | 3.5 | GO:0021933 | radial glia guided migration of cerebellar granule cell(GO:0021933) |
1.7 | 24.2 | GO:0051764 | actin crosslink formation(GO:0051764) |
1.7 | 13.8 | GO:0019227 | neuronal action potential propagation(GO:0019227) detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962) action potential propagation(GO:0098870) |
1.7 | 5.1 | GO:0007525 | somatic muscle development(GO:0007525) |
1.7 | 27.3 | GO:1901629 | regulation of presynaptic membrane organization(GO:1901629) |
1.6 | 3.3 | GO:0060025 | regulation of synaptic activity(GO:0060025) |
1.6 | 1.6 | GO:0030576 | Cajal body organization(GO:0030576) |
1.6 | 14.5 | GO:2001135 | regulation of endocytic recycling(GO:2001135) |
1.6 | 4.7 | GO:0060708 | spongiotrophoblast differentiation(GO:0060708) |
1.6 | 4.7 | GO:0061341 | non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346) |
1.6 | 4.7 | GO:0017085 | response to insecticide(GO:0017085) |
1.6 | 7.8 | GO:0036438 | maintenance of lens transparency(GO:0036438) |
1.6 | 12.4 | GO:0045075 | interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075) |
1.5 | 4.6 | GO:0033326 | cerebrospinal fluid secretion(GO:0033326) |
1.5 | 3.0 | GO:0003096 | renal sodium ion transport(GO:0003096) |
1.5 | 15.1 | GO:2001256 | regulation of store-operated calcium entry(GO:2001256) |
1.5 | 4.5 | GO:0001543 | ovarian follicle rupture(GO:0001543) |
1.5 | 4.5 | GO:0016598 | protein arginylation(GO:0016598) |
1.5 | 5.8 | GO:0010808 | positive regulation of synaptic vesicle priming(GO:0010808) positive regulation of synaptic vesicle exocytosis(GO:2000302) |
1.4 | 18.7 | GO:0043252 | sodium-independent organic anion transport(GO:0043252) |
1.4 | 5.5 | GO:1904425 | negative regulation of GTP binding(GO:1904425) |
1.4 | 24.6 | GO:0001574 | ganglioside biosynthetic process(GO:0001574) |
1.4 | 13.5 | GO:1900112 | regulation of histone H3-K9 trimethylation(GO:1900112) negative regulation of histone H3-K9 trimethylation(GO:1900113) |
1.4 | 4.1 | GO:0060478 | acrosomal vesicle exocytosis(GO:0060478) |
1.3 | 7.9 | GO:0051694 | pointed-end actin filament capping(GO:0051694) |
1.3 | 5.1 | GO:1904694 | negative regulation of vascular smooth muscle contraction(GO:1904694) |
1.3 | 6.4 | GO:0007258 | JUN phosphorylation(GO:0007258) |
1.2 | 6.1 | GO:0031022 | nuclear migration along microfilament(GO:0031022) |
1.2 | 4.8 | GO:1902255 | hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888) positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255) |
1.2 | 3.6 | GO:0035984 | response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984) |
1.2 | 14.4 | GO:0021957 | corticospinal tract morphogenesis(GO:0021957) |
1.2 | 16.6 | GO:0021902 | commitment of neuronal cell to specific neuron type in forebrain(GO:0021902) |
1.2 | 10.6 | GO:0034776 | response to histamine(GO:0034776) cellular response to histamine(GO:0071420) |
1.2 | 4.7 | GO:0001920 | negative regulation of receptor recycling(GO:0001920) |
1.2 | 10.6 | GO:0016198 | axon choice point recognition(GO:0016198) |
1.2 | 18.8 | GO:0035414 | negative regulation of catenin import into nucleus(GO:0035414) |
1.2 | 4.6 | GO:0003344 | pericardium morphogenesis(GO:0003344) |
1.2 | 3.5 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
1.1 | 6.9 | GO:1900042 | positive regulation of interleukin-2 secretion(GO:1900042) |
1.1 | 11.2 | GO:1903608 | protein localization to cytoplasmic stress granule(GO:1903608) |
1.1 | 2.2 | GO:0071550 | death-inducing signaling complex assembly(GO:0071550) |
1.1 | 3.3 | GO:0090285 | negative regulation of protein glycosylation in Golgi(GO:0090285) |
1.1 | 3.3 | GO:1900149 | positive regulation of Schwann cell migration(GO:1900149) |
1.1 | 7.7 | GO:1904217 | regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222) |
1.1 | 4.2 | GO:0001542 | ovulation from ovarian follicle(GO:0001542) |
1.1 | 4.2 | GO:0003056 | regulation of vascular smooth muscle contraction(GO:0003056) |
1.1 | 4.2 | GO:0044861 | protein transport into plasma membrane raft(GO:0044861) |
1.0 | 6.2 | GO:0061343 | cell adhesion involved in heart morphogenesis(GO:0061343) |
1.0 | 12.4 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
1.0 | 4.1 | GO:0045627 | positive regulation of T-helper 1 cell differentiation(GO:0045627) |
1.0 | 5.1 | GO:1900122 | positive regulation of receptor binding(GO:1900122) |
1.0 | 5.1 | GO:0046501 | protoporphyrinogen IX metabolic process(GO:0046501) |
1.0 | 2.0 | GO:0098528 | skeletal muscle fiber differentiation(GO:0098528) |
1.0 | 7.9 | GO:0061368 | behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368) |
1.0 | 7.9 | GO:0032625 | interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619) |
1.0 | 5.9 | GO:1903071 | positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071) |
1.0 | 8.8 | GO:0038180 | nerve growth factor signaling pathway(GO:0038180) |
0.9 | 8.5 | GO:0035507 | regulation of myosin-light-chain-phosphatase activity(GO:0035507) |
0.9 | 5.7 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
0.9 | 2.8 | GO:0036092 | phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092) |
0.9 | 3.7 | GO:0070086 | ubiquitin-dependent endocytosis(GO:0070086) |
0.9 | 2.7 | GO:0002035 | brain renin-angiotensin system(GO:0002035) |
0.9 | 4.5 | GO:1901843 | positive regulation of high voltage-gated calcium channel activity(GO:1901843) |
0.9 | 5.4 | GO:0030035 | microspike assembly(GO:0030035) |
0.9 | 2.7 | GO:0007158 | neuron cell-cell adhesion(GO:0007158) |
0.9 | 2.7 | GO:0009256 | 10-formyltetrahydrofolate metabolic process(GO:0009256) |
0.9 | 15.9 | GO:0046069 | cGMP catabolic process(GO:0046069) |
0.9 | 37.1 | GO:0006376 | mRNA splice site selection(GO:0006376) |
0.9 | 4.4 | GO:0045876 | positive regulation of sister chromatid cohesion(GO:0045876) |
0.9 | 2.6 | GO:1900365 | positive regulation of mRNA polyadenylation(GO:1900365) |
0.9 | 13.2 | GO:1902260 | negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817) |
0.9 | 17.4 | GO:1901385 | regulation of voltage-gated calcium channel activity(GO:1901385) |
0.9 | 8.7 | GO:0071225 | cellular response to muramyl dipeptide(GO:0071225) |
0.9 | 6.0 | GO:0060124 | positive regulation of growth hormone secretion(GO:0060124) |
0.9 | 9.4 | GO:0023041 | neuronal signal transduction(GO:0023041) |
0.8 | 3.4 | GO:0007023 | post-chaperonin tubulin folding pathway(GO:0007023) |
0.8 | 7.5 | GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418) |
0.8 | 5.8 | GO:0014848 | urinary bladder smooth muscle contraction(GO:0014832) urinary tract smooth muscle contraction(GO:0014848) |
0.8 | 0.8 | GO:0046077 | dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077) |
0.8 | 52.8 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
0.8 | 30.1 | GO:0050919 | negative chemotaxis(GO:0050919) |
0.8 | 5.7 | GO:0030718 | germ-line stem cell population maintenance(GO:0030718) |
0.8 | 14.5 | GO:0010758 | regulation of macrophage chemotaxis(GO:0010758) |
0.8 | 5.6 | GO:0031000 | response to caffeine(GO:0031000) |
0.8 | 0.8 | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) |
0.8 | 28.5 | GO:1900449 | regulation of glutamate receptor signaling pathway(GO:1900449) |
0.8 | 8.4 | GO:1901621 | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621) |
0.8 | 7.6 | GO:0045324 | late endosome to vacuole transport(GO:0045324) |
0.7 | 2.2 | GO:0021590 | cerebellum maturation(GO:0021590) |
0.7 | 11.8 | GO:0016242 | negative regulation of macroautophagy(GO:0016242) |
0.7 | 22.7 | GO:0043551 | regulation of phosphatidylinositol 3-kinase activity(GO:0043551) |
0.7 | 3.6 | GO:0045654 | positive regulation of megakaryocyte differentiation(GO:0045654) |
0.7 | 20.9 | GO:0016578 | histone deubiquitination(GO:0016578) |
0.7 | 4.3 | GO:0031584 | activation of phospholipase D activity(GO:0031584) |
0.7 | 14.8 | GO:0008340 | determination of adult lifespan(GO:0008340) |
0.7 | 7.6 | GO:0033623 | regulation of integrin activation(GO:0033623) |
0.7 | 2.7 | GO:0060158 | phospholipase C-activating dopamine receptor signaling pathway(GO:0060158) |
0.7 | 1.4 | GO:0061144 | alveolar secondary septum development(GO:0061144) |
0.7 | 2.0 | GO:0072697 | protein localization to cell cortex(GO:0072697) |
0.7 | 2.0 | GO:0071544 | diphosphoinositol polyphosphate metabolic process(GO:0071543) diphosphoinositol polyphosphate catabolic process(GO:0071544) |
0.7 | 4.0 | GO:1900028 | negative regulation of ruffle assembly(GO:1900028) |
0.7 | 25.1 | GO:0046627 | negative regulation of insulin receptor signaling pathway(GO:0046627) |
0.7 | 2.6 | GO:1902268 | negative regulation of polyamine transmembrane transport(GO:1902268) |
0.6 | 2.6 | GO:0045213 | neurotransmitter receptor metabolic process(GO:0045213) |
0.6 | 5.7 | GO:0090315 | negative regulation of protein targeting to membrane(GO:0090315) |
0.6 | 87.0 | GO:0030041 | actin filament polymerization(GO:0030041) |
0.6 | 3.1 | GO:0050912 | detection of chemical stimulus involved in sensory perception(GO:0050907) detection of chemical stimulus involved in sensory perception of taste(GO:0050912) |
0.6 | 6.2 | GO:0090557 | establishment of endothelial intestinal barrier(GO:0090557) |
0.6 | 7.4 | GO:0034643 | establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497) |
0.6 | 15.8 | GO:0003301 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
0.6 | 1.8 | GO:0031133 | regulation of axon diameter(GO:0031133) |
0.6 | 2.9 | GO:0051967 | negative regulation of synaptic transmission, glutamatergic(GO:0051967) |
0.6 | 45.4 | GO:0001578 | microtubule bundle formation(GO:0001578) |
0.6 | 1.7 | GO:0060392 | negative regulation of SMAD protein import into nucleus(GO:0060392) |
0.6 | 3.4 | GO:0031547 | brain-derived neurotrophic factor receptor signaling pathway(GO:0031547) |
0.5 | 2.2 | GO:0060178 | regulation of exocyst localization(GO:0060178) |
0.5 | 9.2 | GO:0030866 | cortical actin cytoskeleton organization(GO:0030866) |
0.5 | 2.7 | GO:0071476 | cellular hypotonic response(GO:0071476) |
0.5 | 2.7 | GO:0000022 | mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256) |
0.5 | 2.7 | GO:0030643 | cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502) |
0.5 | 39.2 | GO:0000045 | autophagosome assembly(GO:0000045) |
0.5 | 3.1 | GO:0018377 | N-terminal protein myristoylation(GO:0006499) protein myristoylation(GO:0018377) |
0.5 | 3.6 | GO:0019532 | oxalate transport(GO:0019532) |
0.5 | 2.5 | GO:0045650 | negative regulation of macrophage differentiation(GO:0045650) |
0.5 | 5.2 | GO:0007141 | male meiosis I(GO:0007141) |
0.5 | 7.1 | GO:0016926 | protein desumoylation(GO:0016926) |
0.5 | 5.5 | GO:1900383 | regulation of synaptic plasticity by receptor localization to synapse(GO:1900383) |
0.5 | 2.3 | GO:0016601 | Rac protein signal transduction(GO:0016601) |
0.4 | 1.8 | GO:0051012 | microtubule sliding(GO:0051012) |
0.4 | 2.6 | GO:1902993 | positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993) |
0.4 | 3.9 | GO:0015838 | amino-acid betaine transport(GO:0015838) |
0.4 | 9.3 | GO:0007212 | dopamine receptor signaling pathway(GO:0007212) |
0.4 | 9.4 | GO:0095500 | acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145) |
0.4 | 1.2 | GO:1902950 | regulation of dendritic spine maintenance(GO:1902950) positive regulation of dendritic spine maintenance(GO:1902952) |
0.4 | 0.8 | GO:1903351 | response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351) regulation of sodium:potassium-exchanging ATPase activity(GO:1903406) |
0.4 | 2.0 | GO:0072321 | chaperone-mediated protein transport(GO:0072321) |
0.4 | 1.6 | GO:0070164 | negative regulation of adiponectin secretion(GO:0070164) |
0.4 | 3.2 | GO:2000009 | negative regulation of protein localization to cell surface(GO:2000009) |
0.4 | 2.8 | GO:0036265 | RNA (guanine-N7)-methylation(GO:0036265) |
0.4 | 25.9 | GO:0070936 | protein K48-linked ubiquitination(GO:0070936) |
0.4 | 1.6 | GO:0009212 | dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075) |
0.4 | 2.3 | GO:0043508 | negative regulation of JUN kinase activity(GO:0043508) |
0.4 | 26.1 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
0.4 | 4.6 | GO:0008090 | retrograde axonal transport(GO:0008090) |
0.4 | 3.5 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
0.4 | 1.1 | GO:0051683 | establishment of Golgi localization(GO:0051683) |
0.4 | 1.5 | GO:0055071 | cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071) |
0.4 | 1.1 | GO:0034145 | positive regulation of toll-like receptor 4 signaling pathway(GO:0034145) |
0.4 | 5.3 | GO:0048240 | sperm capacitation(GO:0048240) |
0.4 | 5.5 | GO:0031115 | negative regulation of microtubule polymerization(GO:0031115) |
0.4 | 1.1 | GO:0021698 | cerebellar cortex structural organization(GO:0021698) |
0.4 | 8.1 | GO:0061001 | regulation of dendritic spine morphogenesis(GO:0061001) |
0.4 | 7.8 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
0.3 | 0.3 | GO:0010989 | negative regulation of low-density lipoprotein particle clearance(GO:0010989) |
0.3 | 2.4 | GO:0045671 | negative regulation of osteoclast differentiation(GO:0045671) |
0.3 | 6.0 | GO:0010107 | potassium ion import(GO:0010107) |
0.3 | 1.7 | GO:1902775 | mitochondrial large ribosomal subunit assembly(GO:1902775) |
0.3 | 38.2 | GO:0010506 | regulation of autophagy(GO:0010506) |
0.3 | 6.6 | GO:0032292 | myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292) |
0.3 | 51.4 | GO:0007018 | microtubule-based movement(GO:0007018) |
0.3 | 3.9 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
0.3 | 3.2 | GO:0045760 | positive regulation of action potential(GO:0045760) |
0.3 | 18.3 | GO:0002028 | regulation of sodium ion transport(GO:0002028) |
0.3 | 5.0 | GO:0031111 | negative regulation of microtubule polymerization or depolymerization(GO:0031111) |
0.3 | 28.8 | GO:0048813 | dendrite morphogenesis(GO:0048813) |
0.3 | 2.5 | GO:0006044 | N-acetylglucosamine metabolic process(GO:0006044) |
0.3 | 4.0 | GO:0032410 | negative regulation of transporter activity(GO:0032410) |
0.3 | 5.2 | GO:0006828 | manganese ion transport(GO:0006828) |
0.3 | 1.8 | GO:2000008 | regulation of protein localization to cell surface(GO:2000008) |
0.3 | 7.1 | GO:0008053 | mitochondrial fusion(GO:0008053) |
0.3 | 2.4 | GO:0030828 | positive regulation of cGMP biosynthetic process(GO:0030828) |
0.3 | 7.4 | GO:0009299 | mRNA transcription(GO:0009299) |
0.3 | 1.2 | GO:0006867 | asparagine transport(GO:0006867) glutamine transport(GO:0006868) |
0.3 | 5.8 | GO:0035036 | binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) |
0.3 | 14.4 | GO:0001541 | ovarian follicle development(GO:0001541) |
0.3 | 1.7 | GO:1900246 | positive regulation of RIG-I signaling pathway(GO:1900246) |
0.3 | 1.7 | GO:0060017 | parathyroid gland development(GO:0060017) |
0.3 | 4.5 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
0.3 | 1.9 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) |
0.3 | 4.6 | GO:0048305 | immunoglobulin secretion(GO:0048305) |
0.3 | 0.8 | GO:0009838 | abscission(GO:0009838) |
0.3 | 11.7 | GO:0043044 | ATP-dependent chromatin remodeling(GO:0043044) |
0.3 | 4.5 | GO:0002437 | inflammatory response to antigenic stimulus(GO:0002437) |
0.3 | 3.4 | GO:0050832 | defense response to fungus(GO:0050832) |
0.3 | 3.7 | GO:0034394 | protein localization to cell surface(GO:0034394) |
0.3 | 0.8 | GO:0019858 | cytosine metabolic process(GO:0019858) |
0.3 | 2.1 | GO:0033008 | positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306) |
0.3 | 35.7 | GO:0042787 | protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787) |
0.3 | 1.8 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
0.3 | 2.3 | GO:1901409 | regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409) |
0.2 | 0.7 | GO:0006669 | sphinganine-1-phosphate biosynthetic process(GO:0006669) |
0.2 | 20.5 | GO:0019882 | antigen processing and presentation(GO:0019882) |
0.2 | 6.5 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
0.2 | 1.1 | GO:0019086 | late viral transcription(GO:0019086) |
0.2 | 5.4 | GO:0015813 | L-glutamate transport(GO:0015813) |
0.2 | 1.1 | GO:0001675 | acrosome assembly(GO:0001675) |
0.2 | 7.9 | GO:0034605 | cellular response to heat(GO:0034605) |
0.2 | 1.1 | GO:0072429 | response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423) response to intra-S DNA damage checkpoint signaling(GO:0072429) |
0.2 | 1.1 | GO:0015808 | L-alanine transport(GO:0015808) |
0.2 | 5.7 | GO:0006904 | vesicle docking involved in exocytosis(GO:0006904) |
0.2 | 1.7 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
0.2 | 0.4 | GO:0033092 | positive regulation of immature T cell proliferation(GO:0033091) positive regulation of immature T cell proliferation in thymus(GO:0033092) |
0.2 | 0.6 | GO:0035435 | phosphate ion transmembrane transport(GO:0035435) |
0.2 | 2.4 | GO:0016082 | synaptic vesicle priming(GO:0016082) |
0.2 | 3.2 | GO:0043968 | histone H2A acetylation(GO:0043968) |
0.2 | 3.0 | GO:0045653 | negative regulation of megakaryocyte differentiation(GO:0045653) |
0.2 | 5.7 | GO:0008542 | visual behavior(GO:0007632) visual learning(GO:0008542) |
0.2 | 1.7 | GO:0035881 | amacrine cell differentiation(GO:0035881) |
0.2 | 6.0 | GO:0007520 | myoblast fusion(GO:0007520) |
0.2 | 2.3 | GO:0045947 | negative regulation of translational initiation(GO:0045947) |
0.2 | 0.7 | GO:0007352 | zygotic specification of dorsal/ventral axis(GO:0007352) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145) regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900175) positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224) positive regulation of mesoderm development(GO:2000382) |
0.2 | 1.8 | GO:0043982 | histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982) |
0.2 | 0.7 | GO:1902626 | assembly of large subunit precursor of preribosome(GO:1902626) |
0.2 | 9.0 | GO:0007286 | spermatid development(GO:0007286) |
0.2 | 0.7 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
0.2 | 0.9 | GO:0035280 | miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280) |
0.2 | 3.9 | GO:0060291 | long-term synaptic potentiation(GO:0060291) |
0.2 | 0.9 | GO:0000480 | endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480) |
0.2 | 3.5 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
0.2 | 0.3 | GO:1902237 | positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237) |
0.2 | 2.2 | GO:0033198 | response to ATP(GO:0033198) |
0.2 | 3.8 | GO:0006301 | postreplication repair(GO:0006301) |
0.2 | 7.9 | GO:0050777 | negative regulation of immune response(GO:0050777) |
0.2 | 3.8 | GO:0015844 | monoamine transport(GO:0015844) |
0.2 | 0.9 | GO:0006527 | arginine catabolic process(GO:0006527) |
0.2 | 7.8 | GO:0006749 | glutathione metabolic process(GO:0006749) |
0.1 | 0.7 | GO:1902455 | negative regulation of stem cell population maintenance(GO:1902455) |
0.1 | 0.4 | GO:0019372 | lipoxygenase pathway(GO:0019372) |
0.1 | 2.3 | GO:0021702 | cerebellar Purkinje cell differentiation(GO:0021702) |
0.1 | 1.7 | GO:0050995 | negative regulation of lipid catabolic process(GO:0050995) |
0.1 | 1.8 | GO:0030042 | actin filament depolymerization(GO:0030042) |
0.1 | 2.5 | GO:0050853 | B cell receptor signaling pathway(GO:0050853) |
0.1 | 2.3 | GO:0043153 | entrainment of circadian clock by photoperiod(GO:0043153) |
0.1 | 6.2 | GO:0031338 | regulation of vesicle fusion(GO:0031338) |
0.1 | 0.6 | GO:0000056 | ribosomal small subunit export from nucleus(GO:0000056) |
0.1 | 2.3 | GO:0031648 | protein destabilization(GO:0031648) |
0.1 | 0.9 | GO:0032486 | Rap protein signal transduction(GO:0032486) |
0.1 | 3.0 | GO:0072661 | protein targeting to plasma membrane(GO:0072661) |
0.1 | 0.4 | GO:0030327 | prenylated protein catabolic process(GO:0030327) |
0.1 | 0.9 | GO:0046036 | GTP biosynthetic process(GO:0006183) CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036) |
0.1 | 5.0 | GO:0006906 | vesicle fusion(GO:0006906) |
0.1 | 0.8 | GO:0070842 | aggresome assembly(GO:0070842) |
0.1 | 1.8 | GO:0006308 | DNA catabolic process(GO:0006308) |
0.1 | 1.1 | GO:1990403 | embryonic brain development(GO:1990403) |
0.1 | 5.0 | GO:0006892 | post-Golgi vesicle-mediated transport(GO:0006892) |
0.1 | 1.0 | GO:0031468 | nuclear envelope reassembly(GO:0031468) |
0.1 | 0.3 | GO:0035574 | histone H4-K20 demethylation(GO:0035574) |
0.1 | 1.7 | GO:0048599 | oocyte development(GO:0048599) |
0.1 | 4.4 | GO:0048167 | regulation of synaptic plasticity(GO:0048167) |
0.1 | 4.8 | GO:0061077 | chaperone-mediated protein folding(GO:0061077) |
0.1 | 1.5 | GO:0010172 | embryonic body morphogenesis(GO:0010172) |
0.1 | 2.3 | GO:0007218 | neuropeptide signaling pathway(GO:0007218) |
0.1 | 26.6 | GO:0007017 | microtubule-based process(GO:0007017) |
0.1 | 0.5 | GO:0060903 | regulation of meiosis I(GO:0060631) positive regulation of meiosis I(GO:0060903) |
0.1 | 2.7 | GO:0016574 | histone ubiquitination(GO:0016574) |
0.1 | 1.5 | GO:0043666 | regulation of phosphoprotein phosphatase activity(GO:0043666) |
0.1 | 0.6 | GO:0071447 | cellular response to hydroperoxide(GO:0071447) |
0.1 | 0.8 | GO:1902414 | protein localization to cell junction(GO:1902414) |
0.1 | 2.8 | GO:0006836 | neurotransmitter transport(GO:0006836) |
0.1 | 0.2 | GO:0048686 | regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690) |
0.1 | 5.0 | GO:0006814 | sodium ion transport(GO:0006814) |
0.1 | 0.2 | GO:1902309 | negative regulation of peptidyl-serine dephosphorylation(GO:1902309) |
0.1 | 1.7 | GO:0070059 | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059) |
0.1 | 1.2 | GO:0048477 | oogenesis(GO:0048477) |
0.1 | 0.1 | GO:0071879 | regulation of adrenergic receptor signaling pathway(GO:0071877) positive regulation of adrenergic receptor signaling pathway(GO:0071879) |
0.1 | 1.5 | GO:0032331 | negative regulation of chondrocyte differentiation(GO:0032331) |
0.1 | 7.2 | GO:0042384 | cilium assembly(GO:0042384) |
0.1 | 1.6 | GO:0008214 | protein demethylation(GO:0006482) protein dealkylation(GO:0008214) |
0.1 | 0.6 | GO:0031507 | heterochromatin assembly(GO:0031507) |
0.1 | 1.6 | GO:0031333 | negative regulation of protein complex assembly(GO:0031333) |
0.1 | 0.8 | GO:0015693 | magnesium ion transport(GO:0015693) |
0.1 | 8.1 | GO:0006470 | protein dephosphorylation(GO:0006470) |
0.1 | 0.5 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
0.1 | 1.3 | GO:0006491 | N-glycan processing(GO:0006491) |
0.1 | 0.8 | GO:0008535 | respiratory chain complex IV assembly(GO:0008535) |
0.0 | 0.2 | GO:0070966 | nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966) |
0.0 | 4.6 | GO:0046488 | phosphatidylinositol metabolic process(GO:0046488) |
0.0 | 1.3 | GO:0048536 | spleen development(GO:0048536) |
0.0 | 0.7 | GO:0032981 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
0.0 | 2.1 | GO:0042742 | defense response to bacterium(GO:0042742) |
0.0 | 0.2 | GO:0007340 | acrosome reaction(GO:0007340) |
0.0 | 0.3 | GO:0071624 | positive regulation of granulocyte chemotaxis(GO:0071624) positive regulation of neutrophil chemotaxis(GO:0090023) |
0.0 | 0.7 | GO:0044342 | type B pancreatic cell proliferation(GO:0044342) |
0.0 | 0.5 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
0.0 | 0.5 | GO:0045773 | positive regulation of axon extension(GO:0045773) |
0.0 | 0.1 | GO:0034729 | histone H3-K79 methylation(GO:0034729) |
0.0 | 0.1 | GO:2000672 | negative regulation of motor neuron apoptotic process(GO:2000672) |
0.0 | 1.0 | GO:0018107 | peptidyl-threonine phosphorylation(GO:0018107) |
0.0 | 0.4 | GO:0071480 | cellular response to gamma radiation(GO:0071480) |
0.0 | 0.7 | GO:0007062 | sister chromatid cohesion(GO:0007062) |
0.0 | 0.1 | GO:0014067 | negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067) |
0.0 | 0.7 | GO:1902653 | cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653) |
0.0 | 0.2 | GO:0048026 | positive regulation of mRNA splicing, via spliceosome(GO:0048026) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
9.1 | 90.8 | GO:0045298 | tubulin complex(GO:0045298) |
8.3 | 25.0 | GO:0002142 | stereocilia ankle link complex(GO:0002142) |
6.9 | 27.5 | GO:0044307 | dendritic branch(GO:0044307) |
6.5 | 58.2 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
5.7 | 34.0 | GO:1990635 | proximal dendrite(GO:1990635) |
4.5 | 17.9 | GO:0043259 | laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259) |
4.0 | 100.6 | GO:0071565 | nBAF complex(GO:0071565) |
3.6 | 57.4 | GO:0034706 | voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706) |
3.2 | 12.8 | GO:0090537 | CERF complex(GO:0090537) |
3.1 | 24.7 | GO:0001520 | outer dense fiber(GO:0001520) |
2.8 | 11.2 | GO:0097165 | nuclear stress granule(GO:0097165) |
2.8 | 25.0 | GO:0043083 | synaptic cleft(GO:0043083) |
2.7 | 8.2 | GO:0016533 | cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533) |
2.4 | 19.3 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
2.2 | 11.2 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
2.1 | 39.5 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
2.1 | 18.5 | GO:0044327 | dendritic spine head(GO:0044327) |
2.0 | 83.9 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
1.9 | 7.7 | GO:1902737 | dendritic filopodium(GO:1902737) |
1.8 | 5.5 | GO:0032437 | cuticular plate(GO:0032437) |
1.7 | 13.3 | GO:0031315 | extrinsic component of mitochondrial outer membrane(GO:0031315) |
1.6 | 7.8 | GO:0038039 | G-protein coupled receptor heterodimeric complex(GO:0038039) |
1.5 | 18.3 | GO:0000124 | SAGA complex(GO:0000124) |
1.5 | 8.8 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
1.5 | 18.9 | GO:0031528 | microvillus membrane(GO:0031528) |
1.4 | 18.7 | GO:0016342 | catenin complex(GO:0016342) |
1.4 | 6.9 | GO:0036449 | microtubule minus-end(GO:0036449) |
1.4 | 5.5 | GO:0070436 | Grb2-EGFR complex(GO:0070436) |
1.4 | 28.5 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
1.2 | 25.0 | GO:0031430 | M band(GO:0031430) |
1.2 | 57.7 | GO:0031941 | filamentous actin(GO:0031941) |
1.2 | 3.5 | GO:1990037 | Lewy body core(GO:1990037) |
1.2 | 3.5 | GO:0032426 | stereocilium tip(GO:0032426) |
1.2 | 4.6 | GO:0031673 | H zone(GO:0031673) |
1.1 | 3.4 | GO:0044308 | axonal spine(GO:0044308) |
1.1 | 7.5 | GO:0005638 | lamin filament(GO:0005638) |
1.1 | 10.5 | GO:0000138 | Golgi trans cisterna(GO:0000138) |
1.1 | 24.2 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
1.0 | 6.0 | GO:0097427 | microtubule bundle(GO:0097427) |
1.0 | 3.9 | GO:0060187 | cell pole(GO:0060187) |
0.9 | 11.2 | GO:0097449 | astrocyte projection(GO:0097449) |
0.9 | 5.4 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
0.9 | 15.3 | GO:0034704 | calcium channel complex(GO:0034704) |
0.9 | 10.8 | GO:0042581 | specific granule(GO:0042581) |
0.9 | 6.1 | GO:0031933 | telomeric heterochromatin(GO:0031933) |
0.9 | 6.0 | GO:0000322 | storage vacuole(GO:0000322) |
0.8 | 11.6 | GO:0031229 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) |
0.8 | 7.4 | GO:1990909 | Wnt signalosome(GO:1990909) |
0.8 | 52.0 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
0.8 | 37.8 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
0.8 | 1.5 | GO:0097629 | extrinsic component of omegasome membrane(GO:0097629) |
0.8 | 12.1 | GO:0032279 | asymmetric synapse(GO:0032279) |
0.7 | 3.7 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
0.7 | 9.4 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
0.7 | 28.5 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
0.7 | 19.8 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
0.7 | 33.3 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
0.7 | 13.2 | GO:0045334 | clathrin-coated endocytic vesicle(GO:0045334) |
0.7 | 4.1 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
0.7 | 2.7 | GO:1990761 | growth cone lamellipodium(GO:1990761) |
0.7 | 39.1 | GO:0042734 | presynaptic membrane(GO:0042734) |
0.6 | 2.5 | GO:0034993 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
0.6 | 11.2 | GO:1902710 | GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711) |
0.6 | 6.1 | GO:0000815 | ESCRT III complex(GO:0000815) |
0.6 | 37.3 | GO:0005871 | kinesin complex(GO:0005871) |
0.6 | 127.1 | GO:0045211 | postsynaptic membrane(GO:0045211) |
0.6 | 2.4 | GO:0019815 | B cell receptor complex(GO:0019815) |
0.6 | 44.1 | GO:0043204 | perikaryon(GO:0043204) |
0.6 | 92.1 | GO:0001726 | ruffle(GO:0001726) |
0.5 | 40.6 | GO:0043195 | terminal bouton(GO:0043195) |
0.5 | 15.3 | GO:0097440 | apical dendrite(GO:0097440) |
0.5 | 10.6 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
0.5 | 7.1 | GO:0005869 | dynactin complex(GO:0005869) |
0.5 | 2.0 | GO:0005594 | collagen type IX trimer(GO:0005594) |
0.5 | 16.6 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
0.5 | 1.5 | GO:0097524 | sperm plasma membrane(GO:0097524) |
0.5 | 4.7 | GO:0031988 | membrane-bounded vesicle(GO:0031988) |
0.5 | 5.1 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
0.5 | 3.7 | GO:0070688 | MLL5-L complex(GO:0070688) |
0.4 | 5.8 | GO:0002199 | zona pellucida receptor complex(GO:0002199) |
0.4 | 24.6 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
0.4 | 135.1 | GO:0005874 | microtubule(GO:0005874) |
0.4 | 23.7 | GO:0005776 | autophagosome(GO:0005776) |
0.4 | 18.9 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
0.4 | 5.6 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
0.4 | 7.4 | GO:0016235 | aggresome(GO:0016235) |
0.4 | 7.2 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
0.4 | 3.7 | GO:0001739 | sex chromatin(GO:0001739) |
0.4 | 8.3 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
0.3 | 2.7 | GO:0042382 | paraspeckles(GO:0042382) |
0.3 | 4.0 | GO:0042788 | polysomal ribosome(GO:0042788) |
0.3 | 6.8 | GO:0005875 | microtubule associated complex(GO:0005875) |
0.3 | 19.2 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
0.3 | 1.6 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
0.3 | 1.2 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
0.3 | 4.3 | GO:0000780 | condensed nuclear chromosome, centromeric region(GO:0000780) |
0.3 | 18.7 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
0.3 | 2.3 | GO:0045180 | basal cortex(GO:0045180) |
0.3 | 2.2 | GO:0031143 | pseudopodium(GO:0031143) |
0.3 | 2.5 | GO:0000347 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
0.3 | 2.5 | GO:0000812 | Swr1 complex(GO:0000812) |
0.3 | 7.1 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
0.3 | 3.5 | GO:0051233 | spindle midzone(GO:0051233) |
0.3 | 1.9 | GO:0090571 | RNA polymerase II transcription repressor complex(GO:0090571) |
0.3 | 7.0 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
0.3 | 2.4 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
0.2 | 1.1 | GO:0048476 | Holliday junction resolvase complex(GO:0048476) |
0.2 | 3.6 | GO:0005865 | striated muscle thin filament(GO:0005865) |
0.2 | 2.8 | GO:0030027 | lamellipodium(GO:0030027) |
0.2 | 1.9 | GO:0036513 | Derlin-1 retrotranslocation complex(GO:0036513) |
0.2 | 0.7 | GO:0032444 | activin responsive factor complex(GO:0032444) |
0.2 | 2.3 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
0.2 | 11.3 | GO:0031965 | nuclear membrane(GO:0031965) |
0.2 | 1.3 | GO:0030057 | desmosome(GO:0030057) |
0.2 | 0.8 | GO:0070826 | paraferritin complex(GO:0070826) |
0.2 | 0.9 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
0.2 | 5.0 | GO:0035861 | site of double-strand break(GO:0035861) |
0.2 | 0.8 | GO:0042406 | extrinsic component of endoplasmic reticulum membrane(GO:0042406) |
0.1 | 0.6 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
0.1 | 2.8 | GO:0098797 | plasma membrane protein complex(GO:0098797) |
0.1 | 4.5 | GO:0045171 | intercellular bridge(GO:0045171) |
0.1 | 3.4 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
0.1 | 1.9 | GO:0036038 | MKS complex(GO:0036038) |
0.1 | 0.9 | GO:0070578 | RISC-loading complex(GO:0070578) |
0.1 | 4.9 | GO:0043679 | axon terminus(GO:0043679) |
0.1 | 8.2 | GO:0035097 | histone methyltransferase complex(GO:0035097) |
0.1 | 9.1 | GO:0055037 | recycling endosome(GO:0055037) |
0.1 | 1.9 | GO:0031253 | cell projection membrane(GO:0031253) |
0.1 | 2.6 | GO:0005905 | clathrin-coated pit(GO:0005905) |
0.1 | 5.0 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
0.1 | 1.0 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
0.1 | 1.7 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
0.1 | 4.2 | GO:1990391 | DNA repair complex(GO:1990391) |
0.1 | 3.0 | GO:0000788 | nuclear nucleosome(GO:0000788) |
0.1 | 1.0 | GO:0044298 | cell body membrane(GO:0044298) |
0.1 | 2.4 | GO:0008180 | COP9 signalosome(GO:0008180) |
0.1 | 2.1 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
0.1 | 0.4 | GO:0001652 | granular component(GO:0001652) |
0.1 | 8.1 | GO:0005802 | trans-Golgi network(GO:0005802) |
0.1 | 0.6 | GO:0005642 | annulate lamellae(GO:0005642) |
0.1 | 0.5 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
0.1 | 3.8 | GO:0072562 | blood microparticle(GO:0072562) |
0.1 | 1.9 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
0.1 | 8.4 | GO:0015629 | actin cytoskeleton(GO:0015629) |
0.0 | 0.6 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
0.0 | 0.4 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
0.0 | 1.1 | GO:0044437 | vacuolar membrane(GO:0005774) vacuolar part(GO:0044437) |
0.0 | 2.9 | GO:0036064 | ciliary basal body(GO:0036064) |
0.0 | 1.6 | GO:0005801 | cis-Golgi network(GO:0005801) |
0.0 | 13.7 | GO:0005789 | endoplasmic reticulum membrane(GO:0005789) |
0.0 | 2.3 | GO:0005773 | vacuole(GO:0005773) |
0.0 | 1.5 | GO:0098562 | cytoplasmic side of membrane(GO:0098562) |
0.0 | 0.7 | GO:0005753 | mitochondrial proton-transporting ATP synthase complex(GO:0005753) |
0.0 | 1.7 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
0.0 | 0.1 | GO:0097058 | CRLF-CLCF1 complex(GO:0097058) |
0.0 | 0.8 | GO:0016529 | sarcoplasmic reticulum(GO:0016529) |
0.0 | 0.5 | GO:0070069 | cytochrome complex(GO:0070069) |
0.0 | 0.6 | GO:0016592 | mediator complex(GO:0016592) |
0.0 | 6.1 | GO:0005768 | endosome(GO:0005768) |
0.0 | 4.8 | GO:0045202 | synapse(GO:0045202) |
0.0 | 0.4 | GO:0032040 | small-subunit processome(GO:0032040) |
0.0 | 0.5 | GO:0000786 | nucleosome(GO:0000786) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
12.0 | 36.1 | GO:0016155 | formyltetrahydrofolate dehydrogenase activity(GO:0016155) |
8.2 | 65.8 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
8.2 | 40.9 | GO:0003835 | beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835) |
8.1 | 32.5 | GO:0005008 | hepatocyte growth factor-activated receptor activity(GO:0005008) |
6.6 | 26.5 | GO:0035374 | chondroitin sulfate binding(GO:0035374) |
4.6 | 23.0 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
4.3 | 12.8 | GO:0070615 | nucleosome-dependent ATPase activity(GO:0070615) |
4.1 | 24.6 | GO:0003828 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828) |
4.1 | 16.2 | GO:0008332 | low voltage-gated calcium channel activity(GO:0008332) |
3.9 | 90.3 | GO:0034185 | apolipoprotein binding(GO:0034185) |
3.7 | 87.7 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
3.3 | 13.2 | GO:0016909 | JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909) |
3.2 | 22.6 | GO:0031802 | type 5 metabotropic glutamate receptor binding(GO:0031802) |
3.1 | 21.8 | GO:0086006 | voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) |
3.1 | 21.6 | GO:0015016 | [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016) |
3.1 | 21.4 | GO:0046935 | 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935) |
3.0 | 15.1 | GO:0008269 | JAK pathway signal transduction adaptor activity(GO:0008269) |
3.0 | 38.8 | GO:0031005 | filamin binding(GO:0031005) |
2.9 | 46.1 | GO:1905030 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
2.8 | 8.5 | GO:0050656 | 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656) |
2.6 | 7.8 | GO:0008109 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109) |
2.6 | 25.8 | GO:0031749 | D2 dopamine receptor binding(GO:0031749) |
2.5 | 35.5 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
2.5 | 12.4 | GO:0052833 | inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834) |
2.5 | 34.6 | GO:0008601 | protein phosphatase type 2A regulator activity(GO:0008601) |
2.4 | 19.3 | GO:0051434 | BH3 domain binding(GO:0051434) |
2.4 | 14.2 | GO:0000155 | phosphorelay sensor kinase activity(GO:0000155) |
2.2 | 17.9 | GO:0043208 | glycosphingolipid binding(GO:0043208) |
2.2 | 17.3 | GO:0008499 | UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499) |
2.2 | 10.8 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
2.1 | 10.6 | GO:0070326 | very-low-density lipoprotein particle receptor binding(GO:0070326) |
2.1 | 6.3 | GO:0045127 | N-acetylglucosamine kinase activity(GO:0045127) |
2.1 | 35.2 | GO:0008599 | protein phosphatase type 1 regulator activity(GO:0008599) |
2.1 | 18.6 | GO:0003873 | 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331) |
2.0 | 22.3 | GO:0004017 | adenylate kinase activity(GO:0004017) |
2.0 | 2.0 | GO:0070012 | oligopeptidase activity(GO:0070012) |
1.9 | 5.6 | GO:0050827 | toxin receptor binding(GO:0050827) |
1.9 | 11.2 | GO:0070699 | type II activin receptor binding(GO:0070699) |
1.8 | 7.3 | GO:0031800 | type 3 metabotropic glutamate receptor binding(GO:0031800) |
1.8 | 38.2 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
1.8 | 12.5 | GO:0048101 | calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
1.7 | 18.7 | GO:0015347 | sodium-independent organic anion transmembrane transporter activity(GO:0015347) |
1.7 | 5.1 | GO:0008504 | monoamine transmembrane transporter activity(GO:0008504) |
1.7 | 5.1 | GO:0030350 | iron-responsive element binding(GO:0030350) |
1.6 | 19.2 | GO:0022842 | leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842) |
1.6 | 20.7 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
1.6 | 4.7 | GO:0046969 | histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969) |
1.6 | 4.7 | GO:0035650 | AP-1 adaptor complex binding(GO:0035650) |
1.6 | 9.3 | GO:0032051 | clathrin light chain binding(GO:0032051) |
1.5 | 32.6 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
1.5 | 10.3 | GO:0005021 | vascular endothelial growth factor-activated receptor activity(GO:0005021) |
1.4 | 5.7 | GO:0005093 | Rab GDP-dissociation inhibitor activity(GO:0005093) |
1.4 | 5.7 | GO:0005237 | inhibitory extracellular ligand-gated ion channel activity(GO:0005237) |
1.4 | 5.7 | GO:0003938 | IMP dehydrogenase activity(GO:0003938) |
1.4 | 16.7 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
1.4 | 39.3 | GO:0003785 | actin monomer binding(GO:0003785) |
1.3 | 10.8 | GO:0030550 | acetylcholine receptor inhibitor activity(GO:0030550) |
1.3 | 8.0 | GO:0035381 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) |
1.3 | 9.1 | GO:0004716 | receptor signaling protein tyrosine kinase activity(GO:0004716) |
1.3 | 7.8 | GO:0004965 | G-protein coupled GABA receptor activity(GO:0004965) |
1.3 | 5.2 | GO:0000832 | inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724) |
1.3 | 10.1 | GO:0046974 | histone methyltransferase activity (H3-K9 specific)(GO:0046974) |
1.3 | 18.8 | GO:0017128 | phospholipid scramblase activity(GO:0017128) |
1.2 | 3.5 | GO:0030249 | guanylate cyclase regulator activity(GO:0030249) |
1.2 | 19.7 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
1.1 | 4.6 | GO:0030156 | benzodiazepine receptor binding(GO:0030156) |
1.1 | 7.9 | GO:0032795 | heterotrimeric G-protein binding(GO:0032795) |
1.1 | 23.6 | GO:0031489 | myosin V binding(GO:0031489) |
1.1 | 3.3 | GO:0071633 | dihydroceramidase activity(GO:0071633) |
1.1 | 37.3 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
1.1 | 16.1 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
1.1 | 23.2 | GO:0017049 | GTP-Rho binding(GO:0017049) |
1.0 | 3.1 | GO:0008527 | taste receptor activity(GO:0008527) |
1.0 | 31.2 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
1.0 | 14.1 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
1.0 | 3.0 | GO:0001588 | dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588) dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591) |
0.9 | 0.9 | GO:0031697 | beta-1 adrenergic receptor binding(GO:0031697) |
0.9 | 22.3 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
0.9 | 15.7 | GO:0050750 | low-density lipoprotein particle receptor binding(GO:0050750) lipoprotein particle receptor binding(GO:0070325) |
0.9 | 25.6 | GO:0030552 | cAMP binding(GO:0030552) |
0.9 | 2.7 | GO:0004711 | ribosomal protein S6 kinase activity(GO:0004711) |
0.9 | 4.5 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
0.9 | 8.0 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
0.9 | 14.2 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
0.9 | 2.7 | GO:0004477 | methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) |
0.9 | 4.4 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
0.9 | 12.1 | GO:0042288 | MHC class I protein binding(GO:0042288) |
0.9 | 6.9 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
0.8 | 4.2 | GO:0099528 | G-protein coupled neurotransmitter receptor activity(GO:0099528) |
0.8 | 10.9 | GO:0005522 | profilin binding(GO:0005522) |
0.8 | 7.5 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
0.8 | 19.0 | GO:0008330 | protein tyrosine/threonine phosphatase activity(GO:0008330) |
0.8 | 5.7 | GO:0042799 | histone methyltransferase activity (H4-K20 specific)(GO:0042799) |
0.8 | 5.5 | GO:0061665 | SUMO ligase activity(GO:0061665) |
0.8 | 6.9 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
0.8 | 10.8 | GO:0045296 | cadherin binding(GO:0045296) |
0.8 | 165.9 | GO:0008017 | microtubule binding(GO:0008017) |
0.7 | 22.3 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
0.7 | 7.4 | GO:0035612 | AP-2 adaptor complex binding(GO:0035612) |
0.7 | 3.7 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
0.7 | 14.9 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
0.7 | 2.1 | GO:0031826 | type 2A serotonin receptor binding(GO:0031826) |
0.7 | 8.7 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
0.7 | 2.7 | GO:2001070 | glycerophosphocholine phosphodiesterase activity(GO:0047389) starch binding(GO:2001070) |
0.7 | 2.6 | GO:0071532 | ornithine decarboxylase inhibitor activity(GO:0008073) ankyrin repeat binding(GO:0071532) |
0.7 | 30.8 | GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding(GO:0005546) |
0.7 | 15.0 | GO:0004120 | calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715) |
0.6 | 5.1 | GO:0070679 | inositol 1,4,5 trisphosphate binding(GO:0070679) |
0.6 | 1.9 | GO:0035851 | Krueppel-associated box domain binding(GO:0035851) |
0.6 | 3.7 | GO:0042287 | MHC protein binding(GO:0042287) |
0.6 | 6.2 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
0.6 | 1.8 | GO:0015173 | hydrogen:amino acid symporter activity(GO:0005280) aromatic amino acid transmembrane transporter activity(GO:0015173) |
0.6 | 1.8 | GO:0001160 | transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160) |
0.6 | 5.5 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
0.6 | 3.6 | GO:0005227 | calcium activated cation channel activity(GO:0005227) |
0.6 | 1.2 | GO:1904288 | BAT3 complex binding(GO:1904288) |
0.6 | 7.5 | GO:0030332 | cyclin binding(GO:0030332) |
0.6 | 6.3 | GO:0003680 | AT DNA binding(GO:0003680) |
0.6 | 24.2 | GO:0046875 | ephrin receptor binding(GO:0046875) |
0.6 | 1.7 | GO:0005124 | scavenger receptor binding(GO:0005124) |
0.5 | 31.0 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
0.5 | 5.8 | GO:0004622 | lysophospholipase activity(GO:0004622) |
0.5 | 7.3 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
0.5 | 3.6 | GO:0005523 | tropomyosin binding(GO:0005523) |
0.5 | 3.6 | GO:0004311 | farnesyltranstransferase activity(GO:0004311) |
0.5 | 30.9 | GO:0030674 | protein binding, bridging(GO:0030674) |
0.5 | 7.1 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
0.5 | 10.5 | GO:0005521 | lamin binding(GO:0005521) |
0.5 | 16.9 | GO:0017022 | myosin binding(GO:0017022) |
0.5 | 15.9 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
0.5 | 9.3 | GO:0043747 | protein-N-terminal asparagine amidohydrolase activity(GO:0008418) UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity(GO:0008759) iprodione amidohydrolase activity(GO:0018748) (3,5-dichlorophenylurea)acetate amidohydrolase activity(GO:0018749) 4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity(GO:0034571) didemethylisoproturon amidohydrolase activity(GO:0034573) N-isopropylacetanilide amidohydrolase activity(GO:0034576) N-cyclohexylformamide amidohydrolase activity(GO:0034781) isonicotinic acid hydrazide hydrolase activity(GO:0034876) cis-aconitamide amidase activity(GO:0034882) gamma-N-formylaminovinylacetate hydrolase activity(GO:0034885) N2-acetyl-L-lysine deacetylase activity(GO:0043747) O-succinylbenzoate synthase activity(GO:0043748) indoleacetamide hydrolase activity(GO:0043864) N-acetylcitrulline deacetylase activity(GO:0043909) N-acetylgalactosamine-6-phosphate deacetylase activity(GO:0047419) diacetylchitobiose deacetylase activity(GO:0052773) chitooligosaccharide deacetylase activity(GO:0052790) |
0.5 | 4.4 | GO:0001972 | retinoic acid binding(GO:0001972) |
0.5 | 17.6 | GO:0004364 | glutathione transferase activity(GO:0004364) |
0.5 | 4.8 | GO:0042500 | aspartic endopeptidase activity, intramembrane cleaving(GO:0042500) |
0.5 | 7.1 | GO:0016929 | SUMO-specific protease activity(GO:0016929) |
0.5 | 11.4 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
0.4 | 1.8 | GO:0004345 | glucose-6-phosphate dehydrogenase activity(GO:0004345) |
0.4 | 2.7 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
0.4 | 8.8 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
0.4 | 6.5 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
0.4 | 1.7 | GO:0070878 | primary miRNA binding(GO:0070878) |
0.4 | 3.4 | GO:0005451 | monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386) |
0.4 | 6.8 | GO:0010485 | H4 histone acetyltransferase activity(GO:0010485) |
0.4 | 8.4 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
0.4 | 0.8 | GO:0004127 | cytidylate kinase activity(GO:0004127) |
0.4 | 2.1 | GO:0051959 | dynein light intermediate chain binding(GO:0051959) |
0.4 | 118.3 | GO:0043774 | UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738) |
0.4 | 2.0 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
0.4 | 6.8 | GO:0042043 | neurexin family protein binding(GO:0042043) |
0.4 | 4.8 | GO:0000900 | translation repressor activity, nucleic acid binding(GO:0000900) |
0.4 | 7.2 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
0.4 | 3.5 | GO:0001727 | lipid kinase activity(GO:0001727) |
0.4 | 1.9 | GO:0004305 | ethanolamine kinase activity(GO:0004305) |
0.4 | 6.9 | GO:0070402 | NADPH binding(GO:0070402) |
0.4 | 11.1 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
0.4 | 5.7 | GO:0005158 | insulin receptor binding(GO:0005158) |
0.4 | 1.5 | GO:0015410 | manganese-transporting ATPase activity(GO:0015410) |
0.4 | 1.8 | GO:0031996 | thioesterase binding(GO:0031996) |
0.4 | 5.6 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
0.3 | 4.5 | GO:0016755 | transferase activity, transferring amino-acyl groups(GO:0016755) |
0.3 | 2.0 | GO:0008486 | diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) |
0.3 | 17.8 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
0.3 | 3.6 | GO:0019531 | oxalate transmembrane transporter activity(GO:0019531) |
0.3 | 3.3 | GO:0004385 | guanylate kinase activity(GO:0004385) |
0.3 | 8.6 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
0.3 | 15.3 | GO:0051219 | phosphoprotein binding(GO:0051219) |
0.3 | 6.5 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
0.3 | 5.6 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
0.3 | 6.4 | GO:0051721 | protein phosphatase 2A binding(GO:0051721) |
0.3 | 4.9 | GO:0004629 | phospholipase C activity(GO:0004629) |
0.3 | 5.4 | GO:0005313 | L-glutamate transmembrane transporter activity(GO:0005313) |
0.3 | 19.9 | GO:0017048 | Rho GTPase binding(GO:0017048) |
0.3 | 35.6 | GO:0017137 | Rab GTPase binding(GO:0017137) |
0.3 | 9.8 | GO:0018602 | sulfonate dioxygenase activity(GO:0000907) 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity(GO:0018602) hypophosphite dioxygenase activity(GO:0034792) gibberellin 2-beta-dioxygenase activity(GO:0045543) C-19 gibberellin 2-beta-dioxygenase activity(GO:0052634) C-20 gibberellin 2-beta-dioxygenase activity(GO:0052635) |
0.3 | 1.2 | GO:0015186 | L-asparagine transmembrane transporter activity(GO:0015182) L-glutamine transmembrane transporter activity(GO:0015186) |
0.3 | 12.0 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
0.3 | 1.2 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
0.3 | 4.5 | GO:0042805 | actinin binding(GO:0042805) |
0.3 | 5.3 | GO:0003924 | GTPase activity(GO:0003924) |
0.3 | 4.9 | GO:0050840 | extracellular matrix binding(GO:0050840) |
0.3 | 30.4 | GO:0017124 | SH3 domain binding(GO:0017124) |
0.3 | 1.6 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
0.3 | 4.6 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
0.3 | 0.8 | GO:0043546 | molybdopterin cofactor binding(GO:0043546) |
0.3 | 1.3 | GO:0015277 | kainate selective glutamate receptor activity(GO:0015277) |
0.2 | 0.7 | GO:0030618 | transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618) |
0.2 | 10.1 | GO:0015485 | cholesterol binding(GO:0015485) |
0.2 | 4.7 | GO:0005245 | voltage-gated calcium channel activity(GO:0005245) |
0.2 | 7.3 | GO:0001221 | transcription cofactor binding(GO:0001221) |
0.2 | 8.2 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
0.2 | 2.7 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
0.2 | 12.6 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
0.2 | 1.9 | GO:0030957 | Tat protein binding(GO:0030957) |
0.2 | 3.5 | GO:0015301 | anion:anion antiporter activity(GO:0015301) |
0.2 | 3.7 | GO:0017160 | Ral GTPase binding(GO:0017160) |
0.2 | 1.4 | GO:0043423 | 3-phosphoinositide-dependent protein kinase binding(GO:0043423) |
0.2 | 18.8 | GO:0043130 | ubiquitin binding(GO:0043130) |
0.2 | 1.5 | GO:0043560 | insulin receptor substrate binding(GO:0043560) |
0.2 | 1.8 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
0.2 | 1.1 | GO:0008821 | crossover junction endodeoxyribonuclease activity(GO:0008821) |
0.2 | 2.7 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
0.2 | 8.1 | GO:0061733 | peptide-lysine-N-acetyltransferase activity(GO:0061733) |
0.2 | 7.2 | GO:0019003 | GDP binding(GO:0019003) |
0.2 | 4.3 | GO:0003746 | translation elongation factor activity(GO:0003746) |
0.2 | 9.0 | GO:0051117 | ATPase binding(GO:0051117) |
0.2 | 16.7 | GO:0008565 | protein transporter activity(GO:0008565) |
0.2 | 0.8 | GO:0015086 | cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639) |
0.2 | 12.5 | GO:0044325 | ion channel binding(GO:0044325) |
0.2 | 0.6 | GO:0005315 | inorganic phosphate transmembrane transporter activity(GO:0005315) |
0.2 | 0.9 | GO:0016813 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813) |
0.2 | 0.8 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
0.2 | 12.3 | GO:0005516 | calmodulin binding(GO:0005516) |
0.1 | 0.4 | GO:0003963 | RNA-3'-phosphate cyclase activity(GO:0003963) |
0.1 | 0.9 | GO:0001162 | RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162) |
0.1 | 30.8 | GO:0004842 | ubiquitin-protein transferase activity(GO:0004842) |
0.1 | 0.8 | GO:0070579 | methylcytosine dioxygenase activity(GO:0070579) |
0.1 | 4.1 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
0.1 | 1.5 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
0.1 | 0.7 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
0.1 | 2.2 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
0.1 | 6.2 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
0.1 | 2.6 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
0.1 | 2.5 | GO:0034930 | N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131) |
0.1 | 8.0 | GO:0005057 | receptor signaling protein activity(GO:0005057) |
0.1 | 4.3 | GO:0015631 | tubulin binding(GO:0015631) |
0.1 | 5.1 | GO:0002039 | p53 binding(GO:0002039) |
0.1 | 16.6 | GO:0005096 | GTPase activator activity(GO:0005096) |
0.1 | 1.8 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) |
0.1 | 3.1 | GO:0003774 | motor activity(GO:0003774) |
0.1 | 1.5 | GO:0005496 | steroid binding(GO:0005496) |
0.1 | 0.4 | GO:0097027 | ubiquitin-protein transferase activator activity(GO:0097027) |
0.1 | 18.5 | GO:0003779 | actin binding(GO:0003779) |
0.1 | 0.8 | GO:0051787 | misfolded protein binding(GO:0051787) |
0.1 | 15.6 | GO:0005525 | GTP binding(GO:0005525) |
0.1 | 2.7 | GO:0019903 | protein phosphatase binding(GO:0019903) |
0.1 | 1.7 | GO:0018024 | histone-lysine N-methyltransferase activity(GO:0018024) |
0.1 | 0.4 | GO:0005127 | ciliary neurotrophic factor receptor binding(GO:0005127) |
0.1 | 3.7 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
0.1 | 0.8 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
0.1 | 0.4 | GO:0016670 | oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670) |
0.0 | 0.8 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
0.0 | 0.4 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
0.0 | 0.2 | GO:0030371 | translation repressor activity(GO:0030371) |
0.0 | 0.4 | GO:0016701 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
0.0 | 0.5 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
0.0 | 0.3 | GO:0045236 | CXCR chemokine receptor binding(GO:0045236) |
0.0 | 0.1 | GO:0003696 | satellite DNA binding(GO:0003696) |
0.0 | 4.0 | GO:0042277 | peptide binding(GO:0042277) |
0.0 | 0.8 | GO:0005484 | SNAP receptor activity(GO:0005484) |
0.0 | 0.3 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
0.0 | 0.1 | GO:0031690 | adrenergic receptor binding(GO:0031690) |
0.0 | 0.7 | GO:0008748 | N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) NADPH:sulfur oxidoreductase activity(GO:0043914) epoxyqueuosine reductase activity(GO:0052693) |
0.0 | 2.5 | GO:0003714 | transcription corepressor activity(GO:0003714) |
0.0 | 0.2 | GO:0070064 | proline-rich region binding(GO:0070064) |