Motif ID: Sox5_Sry
Z-value: 1.865
Transcription factors associated with Sox5_Sry:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Sox5 | ENSMUSG00000041540.10 | Sox5 |
Sry | ENSMUSG00000069036.3 | Sry |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Sox5 | mm10_v2_chr6_-_144209558_144209647 | 0.54 | 1.3e-06 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
20.1 | 80.3 | GO:2000795 | negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795) |
15.1 | 45.2 | GO:2000297 | negative regulation of synapse maturation(GO:2000297) |
9.2 | 27.6 | GO:0001928 | regulation of exocyst assembly(GO:0001928) |
5.6 | 62.1 | GO:0010650 | positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) |
4.9 | 14.8 | GO:0030827 | negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283) |
3.8 | 26.3 | GO:0060666 | dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666) |
2.4 | 24.5 | GO:0042118 | endothelial cell activation(GO:0042118) |
2.3 | 9.1 | GO:1900740 | regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740) |
2.2 | 31.2 | GO:0021684 | cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) |
2.2 | 13.2 | GO:0021960 | anterior commissure morphogenesis(GO:0021960) retinal bipolar neuron differentiation(GO:0060040) |
2.2 | 8.8 | GO:1904694 | negative regulation of vascular smooth muscle contraction(GO:1904694) |
2.0 | 14.0 | GO:0034047 | regulation of protein phosphatase type 2A activity(GO:0034047) |
1.9 | 7.4 | GO:0044565 | dendritic cell proliferation(GO:0044565) |
1.8 | 12.9 | GO:1900194 | negative regulation of oocyte maturation(GO:1900194) |
1.8 | 8.9 | GO:0046684 | response to pyrethroid(GO:0046684) |
1.6 | 12.9 | GO:0090074 | negative regulation of protein homodimerization activity(GO:0090074) |
1.6 | 3.1 | GO:0046543 | development of secondary sexual characteristics(GO:0045136) development of secondary female sexual characteristics(GO:0046543) |
1.5 | 4.6 | GO:0060023 | soft palate development(GO:0060023) |
1.5 | 4.4 | GO:2000620 | positive regulation of histone H4-K16 acetylation(GO:2000620) |
1.4 | 4.3 | GO:0007290 | spermatid nucleus elongation(GO:0007290) |
1.4 | 7.0 | GO:0010724 | regulation of definitive erythrocyte differentiation(GO:0010724) |
1.3 | 5.4 | GO:0061428 | embryonic heart tube left/right pattern formation(GO:0060971) negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428) |
1.3 | 4.0 | GO:0003357 | noradrenergic neuron differentiation(GO:0003357) |
1.3 | 4.0 | GO:0014877 | response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) |
1.3 | 6.4 | GO:1900122 | positive regulation of receptor binding(GO:1900122) |
1.2 | 7.5 | GO:0051964 | negative regulation of synapse assembly(GO:0051964) |
1.2 | 4.9 | GO:0019355 | nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628) |
1.2 | 4.7 | GO:0042938 | dipeptide transport(GO:0042938) |
1.1 | 20.3 | GO:0021860 | pyramidal neuron development(GO:0021860) |
1.1 | 8.9 | GO:0061368 | behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368) |
1.1 | 4.3 | GO:1903031 | regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) |
1.1 | 5.3 | GO:0071476 | cellular hypotonic response(GO:0071476) |
1.0 | 5.0 | GO:0071787 | endoplasmic reticulum tubular network assembly(GO:0071787) |
1.0 | 4.9 | GO:0016080 | synaptic vesicle targeting(GO:0016080) |
0.9 | 5.6 | GO:0089711 | L-glutamate transmembrane transport(GO:0089711) |
0.9 | 6.5 | GO:0016198 | axon choice point recognition(GO:0016198) |
0.9 | 2.7 | GO:1900039 | positive regulation of cellular response to hypoxia(GO:1900039) |
0.9 | 12.5 | GO:0009312 | oligosaccharide biosynthetic process(GO:0009312) |
0.9 | 11.3 | GO:0032808 | lacrimal gland development(GO:0032808) |
0.9 | 7.8 | GO:0030035 | microspike assembly(GO:0030035) |
0.9 | 6.8 | GO:0035881 | amacrine cell differentiation(GO:0035881) |
0.8 | 2.5 | GO:0001869 | regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869) |
0.8 | 6.6 | GO:0034720 | histone H3-K4 demethylation(GO:0034720) |
0.8 | 8.3 | GO:1903608 | protein localization to cytoplasmic stress granule(GO:1903608) |
0.8 | 30.6 | GO:0048843 | negative regulation of axon extension involved in axon guidance(GO:0048843) |
0.8 | 8.2 | GO:0021902 | commitment of neuronal cell to specific neuron type in forebrain(GO:0021902) |
0.8 | 6.5 | GO:2000809 | neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) positive regulation of synaptic vesicle clustering(GO:2000809) |
0.8 | 1.6 | GO:0035441 | cell migration involved in vasculogenesis(GO:0035441) |
0.7 | 3.0 | GO:0035262 | gonad morphogenesis(GO:0035262) |
0.7 | 6.4 | GO:0035887 | aortic smooth muscle cell differentiation(GO:0035887) |
0.7 | 6.4 | GO:0036371 | protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) |
0.6 | 6.1 | GO:0021796 | cerebral cortex regionalization(GO:0021796) |
0.6 | 2.4 | GO:1902260 | negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817) |
0.6 | 4.3 | GO:0042518 | negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518) |
0.6 | 2.4 | GO:0008627 | intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627) |
0.6 | 1.8 | GO:0036092 | phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092) |
0.6 | 3.5 | GO:2000304 | positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304) |
0.6 | 3.5 | GO:0060164 | regulation of timing of neuron differentiation(GO:0060164) |
0.6 | 2.8 | GO:0008655 | pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097) |
0.5 | 2.2 | GO:0007158 | neuron cell-cell adhesion(GO:0007158) |
0.5 | 11.4 | GO:0008090 | retrograde axonal transport(GO:0008090) |
0.5 | 6.6 | GO:0043252 | sodium-independent organic anion transport(GO:0043252) |
0.5 | 5.6 | GO:2000766 | negative regulation of cytoplasmic translation(GO:2000766) |
0.5 | 12.3 | GO:0030204 | chondroitin sulfate metabolic process(GO:0030204) |
0.5 | 1.4 | GO:2000616 | negative regulation of histone H3-K9 acetylation(GO:2000616) |
0.5 | 6.9 | GO:0031507 | heterochromatin assembly(GO:0031507) |
0.5 | 2.3 | GO:1901668 | regulation of superoxide dismutase activity(GO:1901668) |
0.4 | 2.2 | GO:1900095 | regulation of dosage compensation by inactivation of X chromosome(GO:1900095) |
0.4 | 4.7 | GO:0042572 | retinol metabolic process(GO:0042572) |
0.4 | 12.4 | GO:0060074 | synapse maturation(GO:0060074) |
0.4 | 1.7 | GO:0018076 | N-terminal peptidyl-lysine acetylation(GO:0018076) |
0.4 | 17.8 | GO:0006376 | mRNA splice site selection(GO:0006376) |
0.4 | 4.2 | GO:0021869 | forebrain ventricular zone progenitor cell division(GO:0021869) |
0.4 | 2.9 | GO:0060903 | positive regulation of meiosis I(GO:0060903) |
0.4 | 3.7 | GO:0070933 | histone H4 deacetylation(GO:0070933) |
0.4 | 2.0 | GO:0090164 | asymmetric Golgi ribbon formation(GO:0090164) |
0.4 | 7.4 | GO:0014051 | gamma-aminobutyric acid secretion(GO:0014051) |
0.4 | 3.1 | GO:0032464 | positive regulation of protein homooligomerization(GO:0032464) |
0.4 | 3.8 | GO:0098903 | regulation of membrane repolarization during action potential(GO:0098903) |
0.4 | 1.9 | GO:0021993 | initiation of neural tube closure(GO:0021993) |
0.4 | 4.9 | GO:0060081 | membrane hyperpolarization(GO:0060081) |
0.4 | 1.4 | GO:0000415 | negative regulation of histone H3-K36 methylation(GO:0000415) |
0.3 | 2.4 | GO:0061158 | 3'-UTR-mediated mRNA destabilization(GO:0061158) |
0.3 | 2.0 | GO:0051694 | pointed-end actin filament capping(GO:0051694) |
0.3 | 1.9 | GO:0007144 | female meiosis I(GO:0007144) |
0.3 | 2.9 | GO:0035280 | miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280) |
0.3 | 0.9 | GO:0030210 | heparin biosynthetic process(GO:0030210) |
0.3 | 2.4 | GO:0045075 | interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075) |
0.3 | 1.5 | GO:0010735 | positive regulation of transcription via serum response element binding(GO:0010735) |
0.3 | 4.9 | GO:0097094 | craniofacial suture morphogenesis(GO:0097094) |
0.3 | 0.8 | GO:0044849 | estrous cycle(GO:0044849) |
0.3 | 1.0 | GO:0035063 | nuclear speck organization(GO:0035063) |
0.2 | 0.5 | GO:0048686 | regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690) |
0.2 | 0.5 | GO:0010847 | regulation of chromatin assembly(GO:0010847) |
0.2 | 0.9 | GO:0008078 | mesodermal cell migration(GO:0008078) |
0.2 | 0.4 | GO:1900377 | negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377) |
0.2 | 2.5 | GO:0060539 | diaphragm development(GO:0060539) |
0.2 | 2.4 | GO:0019368 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
0.2 | 3.6 | GO:0002495 | antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) |
0.2 | 6.6 | GO:0030890 | positive regulation of B cell proliferation(GO:0030890) |
0.2 | 1.2 | GO:0034393 | positive regulation of smooth muscle cell apoptotic process(GO:0034393) |
0.2 | 4.5 | GO:0006054 | N-acetylneuraminate metabolic process(GO:0006054) |
0.2 | 3.2 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
0.2 | 8.3 | GO:0036465 | synaptic vesicle recycling(GO:0036465) |
0.2 | 13.6 | GO:0043488 | regulation of mRNA stability(GO:0043488) |
0.2 | 1.3 | GO:0070544 | positive regulation of histone ubiquitination(GO:0033184) histone H3-K36 demethylation(GO:0070544) |
0.2 | 0.7 | GO:0010796 | regulation of multivesicular body size(GO:0010796) |
0.2 | 4.7 | GO:0008053 | mitochondrial fusion(GO:0008053) |
0.2 | 0.5 | GO:0048388 | endosomal lumen acidification(GO:0048388) synaptic vesicle lumen acidification(GO:0097401) |
0.2 | 1.8 | GO:0070102 | interleukin-6-mediated signaling pathway(GO:0070102) |
0.2 | 0.6 | GO:0007113 | endomitotic cell cycle(GO:0007113) |
0.2 | 1.1 | GO:0031536 | positive regulation of exit from mitosis(GO:0031536) |
0.2 | 0.5 | GO:0019074 | viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074) |
0.2 | 1.7 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
0.2 | 1.2 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
0.2 | 2.6 | GO:0006940 | regulation of smooth muscle contraction(GO:0006940) |
0.2 | 1.5 | GO:0051447 | negative regulation of meiotic cell cycle(GO:0051447) |
0.1 | 5.1 | GO:0035329 | hippo signaling(GO:0035329) |
0.1 | 0.7 | GO:0072015 | glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310) |
0.1 | 0.7 | GO:0090292 | nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292) |
0.1 | 9.2 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
0.1 | 0.9 | GO:0060613 | fat pad development(GO:0060613) |
0.1 | 1.7 | GO:1901898 | negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898) |
0.1 | 1.0 | GO:0043374 | CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
0.1 | 1.5 | GO:0070842 | aggresome assembly(GO:0070842) |
0.1 | 0.6 | GO:1902897 | regulation of postsynaptic density protein 95 clustering(GO:1902897) |
0.1 | 4.1 | GO:0072661 | protein targeting to plasma membrane(GO:0072661) |
0.1 | 0.9 | GO:0050930 | induction of positive chemotaxis(GO:0050930) |
0.1 | 0.2 | GO:0071550 | death-inducing signaling complex assembly(GO:0071550) |
0.1 | 3.3 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
0.1 | 2.0 | GO:0005980 | polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247) |
0.1 | 2.8 | GO:0042149 | cellular response to glucose starvation(GO:0042149) |
0.1 | 3.6 | GO:1900449 | regulation of glutamate receptor signaling pathway(GO:1900449) |
0.1 | 3.5 | GO:0006879 | cellular iron ion homeostasis(GO:0006879) |
0.1 | 0.7 | GO:0051418 | interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418) |
0.1 | 4.9 | GO:0051784 | negative regulation of mitotic nuclear division(GO:0045839) negative regulation of nuclear division(GO:0051784) |
0.1 | 0.7 | GO:0033008 | positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306) |
0.1 | 3.3 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
0.1 | 5.8 | GO:0021954 | central nervous system neuron development(GO:0021954) |
0.1 | 3.7 | GO:0001541 | ovarian follicle development(GO:0001541) |
0.1 | 4.3 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
0.1 | 11.1 | GO:0048813 | dendrite morphogenesis(GO:0048813) |
0.1 | 1.5 | GO:0010800 | positive regulation of peptidyl-threonine phosphorylation(GO:0010800) |
0.1 | 2.9 | GO:0016574 | histone ubiquitination(GO:0016574) |
0.1 | 9.9 | GO:0043524 | negative regulation of neuron apoptotic process(GO:0043524) |
0.1 | 1.6 | GO:0018345 | protein palmitoylation(GO:0018345) |
0.1 | 2.1 | GO:1902476 | chloride transmembrane transport(GO:1902476) |
0.1 | 3.1 | GO:0045454 | cell redox homeostasis(GO:0045454) |
0.1 | 1.0 | GO:0061099 | negative regulation of protein tyrosine kinase activity(GO:0061099) |
0.1 | 0.9 | GO:0016973 | poly(A)+ mRNA export from nucleus(GO:0016973) |
0.0 | 0.6 | GO:0010225 | response to UV-C(GO:0010225) |
0.0 | 0.2 | GO:0031584 | activation of phospholipase D activity(GO:0031584) |
0.0 | 4.4 | GO:0002230 | positive regulation of defense response to virus by host(GO:0002230) |
0.0 | 2.7 | GO:2001243 | negative regulation of intrinsic apoptotic signaling pathway(GO:2001243) |
0.0 | 0.1 | GO:1902965 | protein localization to early endosome(GO:1902946) regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966) |
0.0 | 0.5 | GO:0010603 | regulation of cytoplasmic mRNA processing body assembly(GO:0010603) |
0.0 | 0.6 | GO:0043984 | histone H4-K16 acetylation(GO:0043984) |
0.0 | 1.8 | GO:0007599 | blood coagulation(GO:0007596) hemostasis(GO:0007599) |
0.0 | 2.6 | GO:0051028 | mRNA transport(GO:0051028) |
0.0 | 1.0 | GO:0015804 | neutral amino acid transport(GO:0015804) |
0.0 | 5.7 | GO:0006470 | protein dephosphorylation(GO:0006470) |
0.0 | 0.4 | GO:0043968 | histone H2A acetylation(GO:0043968) |
0.0 | 0.9 | GO:0006970 | response to osmotic stress(GO:0006970) |
0.0 | 0.4 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
0.0 | 0.9 | GO:0051092 | positive regulation of NF-kappaB transcription factor activity(GO:0051092) |
0.0 | 0.1 | GO:0035095 | behavioral response to nicotine(GO:0035095) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
3.8 | 80.3 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
3.1 | 62.1 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
2.8 | 11.4 | GO:0031673 | H zone(GO:0031673) |
2.1 | 8.3 | GO:0097165 | nuclear stress granule(GO:0097165) |
1.5 | 14.8 | GO:0044327 | dendritic spine head(GO:0044327) |
1.5 | 4.4 | GO:0097629 | extrinsic component of omegasome membrane(GO:0097629) |
1.3 | 6.6 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
1.1 | 13.8 | GO:0042788 | polysomal ribosome(GO:0042788) |
1.0 | 4.9 | GO:0044316 | cone cell pedicle(GO:0044316) |
0.9 | 6.6 | GO:0019907 | cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) |
0.7 | 14.0 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
0.7 | 11.3 | GO:0034706 | voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706) |
0.6 | 6.9 | GO:0005677 | chromatin silencing complex(GO:0005677) |
0.6 | 5.0 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
0.5 | 1.9 | GO:0005712 | chiasma(GO:0005712) |
0.4 | 13.5 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
0.4 | 2.9 | GO:0070578 | RISC-loading complex(GO:0070578) |
0.4 | 3.8 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
0.4 | 6.4 | GO:0031430 | M band(GO:0031430) |
0.3 | 3.1 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
0.3 | 3.5 | GO:0000137 | Golgi cis cisterna(GO:0000137) |
0.3 | 7.8 | GO:0071565 | nBAF complex(GO:0071565) |
0.3 | 5.6 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
0.3 | 36.7 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.3 | 2.6 | GO:0030478 | actin cap(GO:0030478) |
0.3 | 5.6 | GO:0030673 | axolemma(GO:0030673) |
0.2 | 15.9 | GO:0030425 | dendrite(GO:0030425) |
0.2 | 0.7 | GO:0005816 | spindle pole body(GO:0005816) |
0.2 | 4.0 | GO:0030018 | Z disc(GO:0030018) |
0.2 | 2.7 | GO:0097449 | astrocyte projection(GO:0097449) |
0.2 | 4.3 | GO:0045334 | clathrin-coated endocytic vesicle(GO:0045334) |
0.2 | 4.7 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
0.2 | 7.2 | GO:0032420 | stereocilium(GO:0032420) |
0.2 | 5.3 | GO:0035371 | microtubule plus-end(GO:0035371) |
0.2 | 1.6 | GO:0001739 | sex chromatin(GO:0001739) |
0.2 | 5.1 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
0.1 | 1.7 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
0.1 | 3.6 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
0.1 | 0.5 | GO:0097227 | sperm annulus(GO:0097227) |
0.1 | 8.3 | GO:0005905 | clathrin-coated pit(GO:0005905) |
0.1 | 1.5 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
0.1 | 0.6 | GO:0072487 | MSL complex(GO:0072487) |
0.1 | 0.9 | GO:0046581 | intercellular canaliculus(GO:0046581) |
0.1 | 0.2 | GO:0031143 | pseudopodium(GO:0031143) |
0.1 | 3.2 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
0.1 | 3.2 | GO:0097440 | apical dendrite(GO:0097440) |
0.1 | 2.6 | GO:0034451 | centriolar satellite(GO:0034451) |
0.1 | 0.7 | GO:0005828 | kinetochore microtubule(GO:0005828) |
0.1 | 0.6 | GO:0033503 | HULC complex(GO:0033503) |
0.1 | 2.0 | GO:0005865 | striated muscle thin filament(GO:0005865) |
0.1 | 2.7 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
0.1 | 1.8 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
0.1 | 3.3 | GO:0005801 | cis-Golgi network(GO:0005801) |
0.1 | 3.1 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
0.1 | 2.2 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
0.1 | 0.4 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
0.1 | 0.7 | GO:0034993 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
0.1 | 3.2 | GO:1990391 | DNA repair complex(GO:1990391) |
0.1 | 7.4 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
0.1 | 2.5 | GO:0072562 | blood microparticle(GO:0072562) |
0.1 | 0.8 | GO:0005922 | connexon complex(GO:0005922) |
0.1 | 2.5 | GO:0035097 | histone methyltransferase complex(GO:0035097) |
0.0 | 0.9 | GO:0000346 | transcription export complex(GO:0000346) |
0.0 | 0.2 | GO:0016012 | sarcoglycan complex(GO:0016012) |
0.0 | 4.7 | GO:0016363 | nuclear matrix(GO:0016363) |
0.0 | 2.0 | GO:0016529 | sarcoplasmic reticulum(GO:0016529) |
0.0 | 4.3 | GO:0031514 | motile cilium(GO:0031514) |
0.0 | 6.2 | GO:0005923 | bicellular tight junction(GO:0005923) |
0.0 | 7.4 | GO:0009898 | cytoplasmic side of plasma membrane(GO:0009898) |
0.0 | 6.0 | GO:0045211 | postsynaptic membrane(GO:0045211) |
0.0 | 0.5 | GO:0042581 | specific granule(GO:0042581) |
0.0 | 7.4 | GO:0005802 | trans-Golgi network(GO:0005802) |
0.0 | 9.0 | GO:0014069 | postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572) |
0.0 | 16.8 | GO:0005874 | microtubule(GO:0005874) |
0.0 | 2.2 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
0.0 | 1.2 | GO:0035861 | site of double-strand break(GO:0035861) |
0.0 | 2.2 | GO:0036064 | ciliary basal body(GO:0036064) |
0.0 | 0.4 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
0.0 | 0.2 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
0.0 | 3.1 | GO:0016591 | DNA-directed RNA polymerase II, holoenzyme(GO:0016591) |
0.0 | 1.1 | GO:0045171 | intercellular bridge(GO:0045171) |
0.0 | 0.2 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
0.0 | 7.3 | GO:0048471 | perinuclear region of cytoplasm(GO:0048471) |
0.0 | 2.1 | GO:0043679 | axon terminus(GO:0043679) |
0.0 | 1.1 | GO:0008021 | synaptic vesicle(GO:0008021) |
0.0 | 2.3 | GO:0005777 | peroxisome(GO:0005777) microbody(GO:0042579) |
0.0 | 5.3 | GO:0005764 | lytic vacuole(GO:0000323) lysosome(GO:0005764) |
0.0 | 4.5 | GO:0015629 | actin cytoskeleton(GO:0015629) |
0.0 | 1.6 | GO:0005769 | early endosome(GO:0005769) |
0.0 | 1.7 | GO:0016324 | apical plasma membrane(GO:0016324) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
6.1 | 24.5 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
3.4 | 27.1 | GO:0008499 | UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499) |
2.4 | 26.3 | GO:0038191 | neuropilin binding(GO:0038191) |
2.4 | 16.5 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
2.3 | 68.5 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
2.3 | 11.3 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
2.1 | 74.7 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
1.7 | 1.7 | GO:0001093 | TFIIB-class transcription factor binding(GO:0001093) |
1.6 | 31.5 | GO:0030275 | LRR domain binding(GO:0030275) |
1.4 | 5.6 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
1.2 | 50.5 | GO:0070888 | E-box binding(GO:0070888) |
1.2 | 4.9 | GO:0004515 | nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515) |
1.2 | 7.1 | GO:0070699 | type II activin receptor binding(GO:0070699) |
1.1 | 30.6 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
1.0 | 14.0 | GO:0008601 | protein phosphatase type 2A regulator activity(GO:0008601) |
0.9 | 5.7 | GO:0000900 | translation repressor activity, nucleic acid binding(GO:0000900) |
0.9 | 4.7 | GO:0042895 | antibiotic transporter activity(GO:0042895) |
0.9 | 5.3 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
0.9 | 4.3 | GO:0052833 | inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834) |
0.8 | 20.3 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
0.8 | 11.4 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
0.8 | 3.8 | GO:0004719 | protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719) |
0.7 | 9.4 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
0.7 | 11.7 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
0.7 | 4.7 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
0.6 | 5.0 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
0.6 | 3.1 | GO:0016941 | natriuretic peptide receptor activity(GO:0016941) |
0.6 | 22.0 | GO:0017091 | AU-rich element binding(GO:0017091) |
0.6 | 6.6 | GO:0015347 | sodium-independent organic anion transmembrane transporter activity(GO:0015347) |
0.6 | 2.8 | GO:0004849 | uridine kinase activity(GO:0004849) |
0.5 | 6.4 | GO:0070679 | inositol 1,4,5 trisphosphate binding(GO:0070679) |
0.5 | 2.0 | GO:0000832 | inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724) |
0.5 | 2.5 | GO:0003835 | beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835) |
0.5 | 1.9 | GO:0019237 | centromeric DNA binding(GO:0019237) |
0.5 | 8.9 | GO:0031402 | sodium ion binding(GO:0031402) |
0.4 | 3.5 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
0.4 | 2.0 | GO:0008761 | UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761) |
0.4 | 4.9 | GO:0005522 | profilin binding(GO:0005522) |
0.4 | 1.8 | GO:0050265 | RNA uridylyltransferase activity(GO:0050265) |
0.4 | 4.0 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
0.3 | 1.7 | GO:0004724 | magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724) |
0.3 | 1.3 | GO:0030156 | benzodiazepine receptor binding(GO:0030156) |
0.3 | 3.2 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
0.3 | 7.3 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
0.3 | 0.8 | GO:0038052 | RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052) |
0.3 | 3.8 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
0.3 | 1.6 | GO:0046975 | histone methyltransferase activity (H3-K36 specific)(GO:0046975) |
0.3 | 10.9 | GO:0018602 | sulfonate dioxygenase activity(GO:0000907) 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity(GO:0018602) hypophosphite dioxygenase activity(GO:0034792) gibberellin 2-beta-dioxygenase activity(GO:0045543) C-19 gibberellin 2-beta-dioxygenase activity(GO:0052634) C-20 gibberellin 2-beta-dioxygenase activity(GO:0052635) |
0.3 | 5.6 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
0.3 | 1.5 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
0.2 | 2.0 | GO:0005523 | tropomyosin binding(GO:0005523) |
0.2 | 2.4 | GO:0102338 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
0.2 | 6.3 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
0.2 | 4.9 | GO:0030276 | clathrin binding(GO:0030276) |
0.2 | 1.8 | GO:0001727 | lipid kinase activity(GO:0001727) |
0.2 | 10.4 | GO:0030971 | receptor tyrosine kinase binding(GO:0030971) |
0.2 | 10.1 | GO:0044824 | integrase activity(GO:0008907) T/G mismatch-specific endonuclease activity(GO:0043765) retroviral integrase activity(GO:0044823) retroviral 3' processing activity(GO:0044824) |
0.2 | 7.4 | GO:0001540 | beta-amyloid binding(GO:0001540) |
0.2 | 0.5 | GO:0043532 | angiostatin binding(GO:0043532) |
0.2 | 2.4 | GO:0035613 | RNA stem-loop binding(GO:0035613) |
0.2 | 0.9 | GO:0005166 | neurotrophin p75 receptor binding(GO:0005166) |
0.2 | 0.5 | GO:0008502 | melatonin receptor activity(GO:0008502) |
0.2 | 18.7 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
0.2 | 0.5 | GO:0005030 | neurotrophin receptor activity(GO:0005030) |
0.1 | 2.5 | GO:0001848 | complement binding(GO:0001848) |
0.1 | 4.1 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
0.1 | 34.4 | GO:0008017 | microtubule binding(GO:0008017) |
0.1 | 1.3 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
0.1 | 2.5 | GO:0031078 | histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) |
0.1 | 3.5 | GO:0005245 | voltage-gated calcium channel activity(GO:0005245) |
0.1 | 4.7 | GO:0004364 | glutathione transferase activity(GO:0004364) |
0.1 | 2.0 | GO:0005328 | neurotransmitter:sodium symporter activity(GO:0005328) |
0.1 | 0.5 | GO:0072320 | volume-sensitive chloride channel activity(GO:0072320) |
0.1 | 1.6 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
0.1 | 2.0 | GO:0001871 | pattern binding(GO:0001871) polysaccharide binding(GO:0030247) |
0.1 | 3.9 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
0.1 | 11.4 | GO:0051117 | ATPase binding(GO:0051117) |
0.1 | 16.3 | GO:0003714 | transcription corepressor activity(GO:0003714) |
0.1 | 0.9 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
0.1 | 0.5 | GO:0050692 | DBD domain binding(GO:0050692) |
0.1 | 3.2 | GO:0015485 | cholesterol binding(GO:0015485) |
0.1 | 0.4 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
0.1 | 1.6 | GO:0019706 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) |
0.1 | 1.3 | GO:0070566 | adenylyltransferase activity(GO:0070566) |
0.1 | 3.3 | GO:0030674 | protein binding, bridging(GO:0030674) |
0.1 | 0.5 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
0.1 | 0.6 | GO:0070742 | C2H2 zinc finger domain binding(GO:0070742) |
0.1 | 1.1 | GO:0004385 | guanylate kinase activity(GO:0004385) |
0.1 | 0.7 | GO:0005521 | lamin binding(GO:0005521) |
0.1 | 12.6 | GO:0061630 | ubiquitin protein ligase activity(GO:0061630) |
0.0 | 0.6 | GO:0008641 | small protein activating enzyme activity(GO:0008641) |
0.0 | 6.5 | GO:1901981 | phosphatidylinositol phosphate binding(GO:1901981) |
0.0 | 6.6 | GO:0017124 | SH3 domain binding(GO:0017124) |
0.0 | 1.0 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
0.0 | 0.6 | GO:0097602 | cullin family protein binding(GO:0097602) |
0.0 | 3.4 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
0.0 | 2.0 | GO:0043531 | ADP binding(GO:0043531) |
0.0 | 2.5 | GO:0003743 | translation initiation factor activity(GO:0003743) |
0.0 | 3.5 | GO:0008565 | protein transporter activity(GO:0008565) |
0.0 | 0.5 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
0.0 | 0.5 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
0.0 | 1.3 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
0.0 | 0.5 | GO:0070530 | K63-linked polyubiquitin binding(GO:0070530) |
0.0 | 0.6 | GO:0003730 | mRNA 3'-UTR binding(GO:0003730) |