Motif ID: Sp100
Z-value: 2.932
Transcription factors associated with Sp100:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Sp100 | ENSMUSG00000026222.10 | Sp100 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Sp100 | mm10_v2_chr1_+_85650044_85650052 | 0.21 | 7.5e-02 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.6 | 28.1 | GO:0021764 | amygdala development(GO:0021764) |
| 5.3 | 26.4 | GO:0051315 | attachment of mitotic spindle microtubules to kinetochore(GO:0051315) |
| 4.2 | 29.2 | GO:0010273 | detoxification of copper ion(GO:0010273) cellular response to zinc ion(GO:0071294) stress response to copper ion(GO:1990169) |
| 3.5 | 17.3 | GO:0003431 | growth plate cartilage chondrocyte development(GO:0003431) |
| 3.2 | 9.5 | GO:0035441 | cell migration involved in vasculogenesis(GO:0035441) metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262) |
| 3.0 | 18.2 | GO:0046602 | regulation of mitotic centrosome separation(GO:0046602) |
| 2.7 | 8.2 | GO:0006553 | lysine metabolic process(GO:0006553) |
| 2.6 | 18.2 | GO:0031508 | pericentric heterochromatin assembly(GO:0031508) |
| 2.3 | 11.5 | GO:1903026 | negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026) |
| 2.0 | 6.0 | GO:1904569 | regulation of selenocysteine incorporation(GO:1904569) |
| 1.8 | 9.0 | GO:0006564 | L-serine biosynthetic process(GO:0006564) |
| 1.7 | 16.5 | GO:0046036 | GTP biosynthetic process(GO:0006183) CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036) |
| 1.5 | 12.1 | GO:0044027 | hypermethylation of CpG island(GO:0044027) |
| 1.5 | 4.4 | GO:0045819 | positive regulation of glycogen catabolic process(GO:0045819) |
| 1.3 | 6.4 | GO:0032237 | activation of store-operated calcium channel activity(GO:0032237) |
| 1.2 | 11.1 | GO:0045719 | negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874) |
| 1.1 | 19.6 | GO:0030213 | hyaluronan biosynthetic process(GO:0030213) |
| 1.1 | 4.3 | GO:2000383 | regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384) |
| 1.0 | 7.3 | GO:0030916 | otic vesicle formation(GO:0030916) |
| 1.0 | 3.1 | GO:2000852 | regulation of corticosterone secretion(GO:2000852) |
| 1.0 | 1.0 | GO:0061511 | centriole elongation(GO:0061511) |
| 1.0 | 2.0 | GO:1900041 | negative regulation of interleukin-2 secretion(GO:1900041) |
| 0.9 | 4.5 | GO:1902373 | negative regulation of mRNA catabolic process(GO:1902373) |
| 0.9 | 3.5 | GO:1904192 | prostate gland stromal morphogenesis(GO:0060741) cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193) |
| 0.8 | 14.4 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
| 0.8 | 24.8 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 0.8 | 2.4 | GO:0032650 | regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730) interleukin-1 alpha secretion(GO:0050703) |
| 0.8 | 13.6 | GO:0042347 | negative regulation of NF-kappaB import into nucleus(GO:0042347) |
| 0.8 | 3.2 | GO:0072697 | protein localization to cell cortex(GO:0072697) |
| 0.8 | 14.2 | GO:0090136 | epithelial cell-cell adhesion(GO:0090136) |
| 0.8 | 3.9 | GO:0072015 | glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310) |
| 0.7 | 2.8 | GO:0072344 | rescue of stalled ribosome(GO:0072344) |
| 0.7 | 2.6 | GO:0006348 | chromatin silencing at telomere(GO:0006348) |
| 0.6 | 8.4 | GO:0071257 | cellular response to electrical stimulus(GO:0071257) |
| 0.6 | 6.1 | GO:0045899 | positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899) |
| 0.6 | 5.3 | GO:0035330 | regulation of hippo signaling(GO:0035330) |
| 0.6 | 9.8 | GO:0032060 | bleb assembly(GO:0032060) |
| 0.6 | 1.7 | GO:0060126 | somatotropin secreting cell differentiation(GO:0060126) |
| 0.6 | 3.3 | GO:0006627 | protein processing involved in protein targeting to mitochondrion(GO:0006627) |
| 0.5 | 4.2 | GO:0060665 | response to hepatocyte growth factor(GO:0035728) cellular response to hepatocyte growth factor stimulus(GO:0035729) regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665) |
| 0.5 | 12.2 | GO:0010569 | regulation of double-strand break repair via homologous recombination(GO:0010569) |
| 0.5 | 2.4 | GO:0006167 | AMP biosynthetic process(GO:0006167) |
| 0.5 | 2.4 | GO:0040032 | post-embryonic body morphogenesis(GO:0040032) |
| 0.5 | 2.8 | GO:0006384 | transcription initiation from RNA polymerase III promoter(GO:0006384) |
| 0.5 | 3.3 | GO:1902065 | response to L-glutamate(GO:1902065) |
| 0.5 | 9.2 | GO:0032981 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
| 0.4 | 2.2 | GO:0014886 | transition between slow and fast fiber(GO:0014886) |
| 0.4 | 25.2 | GO:0070303 | negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303) |
| 0.4 | 5.8 | GO:0045910 | negative regulation of DNA recombination(GO:0045910) |
| 0.4 | 2.4 | GO:2000210 | positive regulation of anoikis(GO:2000210) |
| 0.4 | 1.2 | GO:0001732 | formation of cytoplasmic translation initiation complex(GO:0001732) |
| 0.4 | 1.2 | GO:0097089 | methyl-branched fatty acid metabolic process(GO:0097089) |
| 0.4 | 3.5 | GO:0009396 | folic acid-containing compound biosynthetic process(GO:0009396) |
| 0.3 | 17.7 | GO:0035307 | positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307) |
| 0.3 | 6.2 | GO:0071577 | zinc II ion transmembrane transport(GO:0071577) |
| 0.3 | 6.1 | GO:0000920 | cell separation after cytokinesis(GO:0000920) |
| 0.3 | 3.9 | GO:0000463 | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) |
| 0.3 | 2.9 | GO:0071318 | cellular response to ATP(GO:0071318) |
| 0.3 | 0.9 | GO:0015772 | disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772) |
| 0.3 | 9.7 | GO:0010972 | negative regulation of G2/M transition of mitotic cell cycle(GO:0010972) |
| 0.3 | 2.9 | GO:0051103 | lagging strand elongation(GO:0006273) DNA ligation involved in DNA repair(GO:0051103) |
| 0.3 | 2.8 | GO:0032464 | positive regulation of protein homooligomerization(GO:0032464) |
| 0.3 | 2.9 | GO:0061299 | retina vasculature morphogenesis in camera-type eye(GO:0061299) |
| 0.3 | 1.0 | GO:0070162 | adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163) negative regulation of adiponectin secretion(GO:0070164) |
| 0.2 | 20.4 | GO:0001578 | microtubule bundle formation(GO:0001578) |
| 0.2 | 1.7 | GO:0001675 | acrosome assembly(GO:0001675) |
| 0.2 | 6.6 | GO:0006182 | cGMP biosynthetic process(GO:0006182) |
| 0.2 | 3.0 | GO:0009083 | branched-chain amino acid catabolic process(GO:0009083) |
| 0.2 | 14.6 | GO:0006635 | fatty acid beta-oxidation(GO:0006635) |
| 0.2 | 7.5 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
| 0.2 | 7.1 | GO:0021511 | spinal cord patterning(GO:0021511) |
| 0.2 | 3.3 | GO:0016188 | synaptic vesicle maturation(GO:0016188) |
| 0.2 | 4.7 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 0.2 | 1.2 | GO:0090209 | negative regulation of triglyceride metabolic process(GO:0090209) |
| 0.2 | 2.7 | GO:0045742 | positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) |
| 0.2 | 5.7 | GO:0006783 | heme biosynthetic process(GO:0006783) |
| 0.2 | 6.6 | GO:0007405 | neuroblast proliferation(GO:0007405) |
| 0.2 | 1.0 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
| 0.1 | 6.1 | GO:0032781 | positive regulation of ATPase activity(GO:0032781) |
| 0.1 | 2.7 | GO:0048026 | positive regulation of mRNA splicing, via spliceosome(GO:0048026) |
| 0.1 | 6.5 | GO:0046513 | ceramide biosynthetic process(GO:0046513) |
| 0.1 | 5.4 | GO:1901998 | toxin transport(GO:1901998) |
| 0.1 | 5.5 | GO:0060325 | face morphogenesis(GO:0060325) |
| 0.1 | 5.6 | GO:0007257 | activation of JUN kinase activity(GO:0007257) |
| 0.1 | 1.7 | GO:0048714 | positive regulation of oligodendrocyte differentiation(GO:0048714) |
| 0.1 | 15.0 | GO:0051028 | mRNA transport(GO:0051028) |
| 0.1 | 11.2 | GO:2000177 | regulation of neural precursor cell proliferation(GO:2000177) |
| 0.1 | 6.7 | GO:0070613 | regulation of protein processing(GO:0070613) |
| 0.1 | 2.2 | GO:0008608 | attachment of spindle microtubules to kinetochore(GO:0008608) |
| 0.1 | 1.4 | GO:0032506 | cytokinetic process(GO:0032506) |
| 0.1 | 5.7 | GO:0034620 | cellular response to unfolded protein(GO:0034620) |
| 0.1 | 3.9 | GO:0006506 | GPI anchor biosynthetic process(GO:0006506) |
| 0.1 | 4.6 | GO:0006970 | response to osmotic stress(GO:0006970) |
| 0.1 | 0.5 | GO:0060768 | epithelial cell proliferation involved in prostate gland development(GO:0060767) regulation of epithelial cell proliferation involved in prostate gland development(GO:0060768) negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770) |
| 0.1 | 0.4 | GO:0046016 | regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) late viral transcription(GO:0019086) positive regulation of transcription by glucose(GO:0046016) |
| 0.1 | 18.8 | GO:0007059 | chromosome segregation(GO:0007059) |
| 0.1 | 1.0 | GO:0002082 | regulation of oxidative phosphorylation(GO:0002082) |
| 0.1 | 4.9 | GO:0043966 | histone H3 acetylation(GO:0043966) |
| 0.1 | 3.4 | GO:0046785 | microtubule polymerization(GO:0046785) |
| 0.1 | 1.7 | GO:1903146 | regulation of mitophagy(GO:1903146) |
| 0.1 | 0.7 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
| 0.1 | 1.0 | GO:0044030 | regulation of DNA methylation(GO:0044030) |
| 0.1 | 0.8 | GO:0019363 | pyridine nucleotide biosynthetic process(GO:0019363) |
| 0.0 | 0.5 | GO:1900364 | negative regulation of mRNA polyadenylation(GO:1900364) |
| 0.0 | 0.0 | GO:0032240 | negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832) |
| 0.0 | 0.6 | GO:0036065 | fucosylation(GO:0036065) |
| 0.0 | 1.4 | GO:0007088 | regulation of mitotic nuclear division(GO:0007088) |
| 0.0 | 2.3 | GO:0032543 | mitochondrial translation(GO:0032543) |
| 0.0 | 2.1 | GO:0035914 | skeletal muscle cell differentiation(GO:0035914) |
| 0.0 | 2.6 | GO:0072332 | intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332) |
| 0.0 | 2.5 | GO:0060999 | positive regulation of dendritic spine development(GO:0060999) |
| 0.0 | 5.5 | GO:0007067 | mitotic nuclear division(GO:0007067) |
| 0.0 | 0.3 | GO:0016226 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
| 0.0 | 0.1 | GO:0030205 | glycosaminoglycan catabolic process(GO:0006027) dermatan sulfate metabolic process(GO:0030205) |
| 0.0 | 1.9 | GO:0071356 | cellular response to tumor necrosis factor(GO:0071356) |
| 0.0 | 1.8 | GO:2000045 | regulation of G1/S transition of mitotic cell cycle(GO:2000045) |
| 0.0 | 11.0 | GO:0007186 | G-protein coupled receptor signaling pathway(GO:0007186) |
| 0.0 | 1.3 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
| 0.0 | 3.1 | GO:0009101 | glycoprotein biosynthetic process(GO:0009101) |
| 0.0 | 1.0 | GO:0006342 | chromatin silencing(GO:0006342) |
| 0.0 | 0.2 | GO:0032784 | regulation of DNA-templated transcription, elongation(GO:0032784) |
| 0.0 | 0.8 | GO:0015992 | proton transport(GO:0015992) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.7 | 14.2 | GO:0034684 | integrin alphav-beta5 complex(GO:0034684) |
| 3.4 | 20.5 | GO:0000444 | MIS12/MIND type complex(GO:0000444) |
| 3.4 | 13.6 | GO:0043293 | apoptosome(GO:0043293) |
| 2.9 | 26.4 | GO:0000778 | condensed nuclear chromosome kinetochore(GO:0000778) |
| 1.8 | 5.3 | GO:0097543 | ciliary inversin compartment(GO:0097543) |
| 1.3 | 17.3 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 1.1 | 3.3 | GO:0042720 | mitochondrial inner membrane peptidase complex(GO:0042720) |
| 1.1 | 3.2 | GO:0031417 | NatC complex(GO:0031417) |
| 0.9 | 3.5 | GO:0036454 | insulin-like growth factor binding protein complex(GO:0016942) alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567) |
| 0.8 | 7.3 | GO:0061574 | ASAP complex(GO:0061574) |
| 0.8 | 2.4 | GO:0031074 | nucleocytoplasmic shuttling complex(GO:0031074) |
| 0.8 | 7.8 | GO:0045298 | tubulin complex(GO:0045298) |
| 0.8 | 17.9 | GO:0001741 | XY body(GO:0001741) |
| 0.8 | 3.0 | GO:0005947 | mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) |
| 0.7 | 2.2 | GO:1990047 | spindle matrix(GO:1990047) |
| 0.7 | 6.6 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.7 | 22.8 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
| 0.7 | 7.0 | GO:0032797 | SMN complex(GO:0032797) |
| 0.7 | 4.9 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
| 0.6 | 6.1 | GO:0031595 | nuclear proteasome complex(GO:0031595) |
| 0.6 | 6.6 | GO:0010369 | chromocenter(GO:0010369) |
| 0.5 | 12.3 | GO:0045334 | clathrin-coated endocytic vesicle(GO:0045334) |
| 0.4 | 20.8 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.4 | 13.1 | GO:0000788 | nuclear nucleosome(GO:0000788) |
| 0.4 | 6.8 | GO:0035102 | PRC1 complex(GO:0035102) |
| 0.4 | 6.4 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
| 0.4 | 5.3 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
| 0.3 | 6.6 | GO:0031527 | filopodium membrane(GO:0031527) |
| 0.3 | 5.7 | GO:0097225 | sperm midpiece(GO:0097225) |
| 0.3 | 12.0 | GO:0000786 | nucleosome(GO:0000786) |
| 0.3 | 8.7 | GO:0035145 | exon-exon junction complex(GO:0035145) |
| 0.3 | 18.2 | GO:0000794 | condensed nuclear chromosome(GO:0000794) |
| 0.3 | 2.2 | GO:0000127 | transcription factor TFIIIC complex(GO:0000127) |
| 0.3 | 3.5 | GO:0001527 | microfibril(GO:0001527) |
| 0.3 | 1.8 | GO:0097255 | R2TP complex(GO:0097255) |
| 0.3 | 4.5 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
| 0.2 | 3.2 | GO:0042788 | polysomal ribosome(GO:0042788) |
| 0.2 | 2.9 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 0.2 | 2.6 | GO:0048188 | MLL3/4 complex(GO:0044666) Set1C/COMPASS complex(GO:0048188) |
| 0.2 | 2.4 | GO:0031229 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) |
| 0.2 | 4.6 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.2 | 13.2 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.2 | 2.5 | GO:0032156 | septin cytoskeleton(GO:0032156) |
| 0.1 | 10.4 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.1 | 1.4 | GO:0070938 | contractile ring(GO:0070938) |
| 0.1 | 1.2 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
| 0.1 | 7.8 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.1 | 4.6 | GO:0005876 | spindle microtubule(GO:0005876) |
| 0.1 | 1.7 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
| 0.1 | 7.1 | GO:0000792 | heterochromatin(GO:0000792) |
| 0.1 | 6.7 | GO:0000313 | organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761) |
| 0.1 | 2.4 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 0.1 | 1.6 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
| 0.1 | 0.8 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
| 0.1 | 2.0 | GO:0030904 | retromer complex(GO:0030904) |
| 0.1 | 6.5 | GO:0005901 | caveola(GO:0005901) |
| 0.1 | 4.7 | GO:0071013 | catalytic step 2 spliceosome(GO:0071013) |
| 0.1 | 0.6 | GO:0005688 | U6 snRNP(GO:0005688) |
| 0.1 | 1.3 | GO:0030137 | COPI-coated vesicle(GO:0030137) |
| 0.0 | 5.5 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
| 0.0 | 17.4 | GO:0005925 | focal adhesion(GO:0005925) |
| 0.0 | 4.1 | GO:0005681 | spliceosomal complex(GO:0005681) |
| 0.0 | 309.3 | GO:0005575 | cellular_component(GO:0005575) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 6.6 | 26.4 | GO:0043515 | kinetochore binding(GO:0043515) |
| 6.1 | 18.2 | GO:0035402 | histone kinase activity (H3-T11 specific)(GO:0035402) |
| 3.0 | 9.0 | GO:0004647 | phosphoserine phosphatase activity(GO:0004647) |
| 1.9 | 9.5 | GO:0038085 | vascular endothelial growth factor binding(GO:0038085) |
| 1.6 | 6.4 | GO:0051032 | nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033) |
| 1.5 | 12.1 | GO:0051718 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718) |
| 1.5 | 7.4 | GO:0004165 | dodecenoyl-CoA delta-isomerase activity(GO:0004165) |
| 1.5 | 4.4 | GO:0000402 | open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402) |
| 1.2 | 15.7 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
| 1.2 | 5.8 | GO:0000403 | Y-form DNA binding(GO:0000403) |
| 1.1 | 12.2 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
| 1.0 | 8.3 | GO:0018741 | alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902) |
| 0.9 | 2.7 | GO:0071568 | UFM1 transferase activity(GO:0071568) |
| 0.9 | 6.1 | GO:0036402 | proteasome-activating ATPase activity(GO:0036402) |
| 0.9 | 6.0 | GO:0035368 | selenocysteine insertion sequence binding(GO:0035368) |
| 0.8 | 16.5 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
| 0.8 | 6.5 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
| 0.7 | 6.6 | GO:0004383 | guanylate cyclase activity(GO:0004383) |
| 0.7 | 12.5 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 0.6 | 26.1 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.6 | 2.4 | GO:0035381 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) |
| 0.6 | 29.2 | GO:0005507 | copper ion binding(GO:0005507) |
| 0.6 | 8.9 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
| 0.6 | 2.8 | GO:0004045 | aminoacyl-tRNA hydrolase activity(GO:0004045) |
| 0.5 | 9.8 | GO:0051920 | peroxiredoxin activity(GO:0051920) |
| 0.5 | 2.9 | GO:0003910 | DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910) |
| 0.5 | 17.3 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.5 | 21.0 | GO:0097472 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472) |
| 0.4 | 8.0 | GO:0070628 | proteasome binding(GO:0070628) |
| 0.4 | 2.9 | GO:0046790 | virion binding(GO:0046790) |
| 0.4 | 28.1 | GO:0003707 | steroid hormone receptor activity(GO:0003707) |
| 0.4 | 8.2 | GO:0016646 | oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646) |
| 0.3 | 5.5 | GO:0070182 | DNA polymerase binding(GO:0070182) |
| 0.3 | 6.4 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.3 | 7.3 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.3 | 0.9 | GO:0008515 | sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157) |
| 0.3 | 12.7 | GO:0051539 | 4 iron, 4 sulfur cluster binding(GO:0051539) |
| 0.3 | 6.6 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.3 | 1.7 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
| 0.3 | 1.7 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.3 | 2.4 | GO:0031698 | beta-2 adrenergic receptor binding(GO:0031698) |
| 0.3 | 3.0 | GO:0016624 | oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624) |
| 0.2 | 0.7 | GO:0004140 | dephospho-CoA kinase activity(GO:0004140) |
| 0.2 | 5.7 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
| 0.2 | 3.5 | GO:0005542 | folic acid binding(GO:0005542) |
| 0.2 | 3.0 | GO:0070402 | NADPH binding(GO:0070402) |
| 0.2 | 4.2 | GO:0042056 | chemoattractant activity(GO:0042056) |
| 0.2 | 4.9 | GO:0008607 | phosphorylase kinase regulator activity(GO:0008607) |
| 0.2 | 6.1 | GO:0001671 | ATPase activator activity(GO:0001671) |
| 0.2 | 4.0 | GO:0043747 | protein-N-terminal asparagine amidohydrolase activity(GO:0008418) UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity(GO:0008759) iprodione amidohydrolase activity(GO:0018748) (3,5-dichlorophenylurea)acetate amidohydrolase activity(GO:0018749) 4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity(GO:0034571) didemethylisoproturon amidohydrolase activity(GO:0034573) N-isopropylacetanilide amidohydrolase activity(GO:0034576) N-cyclohexylformamide amidohydrolase activity(GO:0034781) isonicotinic acid hydrazide hydrolase activity(GO:0034876) cis-aconitamide amidase activity(GO:0034882) gamma-N-formylaminovinylacetate hydrolase activity(GO:0034885) N2-acetyl-L-lysine deacetylase activity(GO:0043747) O-succinylbenzoate synthase activity(GO:0043748) indoleacetamide hydrolase activity(GO:0043864) N-acetylcitrulline deacetylase activity(GO:0043909) N-acetylgalactosamine-6-phosphate deacetylase activity(GO:0047419) diacetylchitobiose deacetylase activity(GO:0052773) chitooligosaccharide deacetylase activity(GO:0052790) |
| 0.2 | 1.7 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
| 0.2 | 4.9 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.2 | 17.7 | GO:0005178 | integrin binding(GO:0005178) |
| 0.2 | 2.9 | GO:0035497 | cAMP response element binding(GO:0035497) |
| 0.2 | 7.1 | GO:0005160 | transforming growth factor beta receptor binding(GO:0005160) |
| 0.1 | 3.3 | GO:0019706 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) |
| 0.1 | 2.6 | GO:0035380 | C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) mevaldate reductase activity(GO:0004495) gluconate dehydrogenase activity(GO:0008875) epoxide dehydrogenase activity(GO:0018451) 5-exo-hydroxycamphor dehydrogenase activity(GO:0018452) 2-hydroxytetrahydrofuran dehydrogenase activity(GO:0018453) acetoin dehydrogenase activity(GO:0019152) phenylcoumaran benzylic ether reductase activity(GO:0032442) D-xylose:NADP reductase activity(GO:0032866) L-arabinose:NADP reductase activity(GO:0032867) D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity(GO:0033709) (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity(GO:0034831) 3-hydroxymenthone dehydrogenase activity(GO:0034840) very long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0035380) dihydrotestosterone 17-beta-dehydrogenase activity(GO:0035410) (R)-2-hydroxyisocaproate dehydrogenase activity(GO:0043713) L-arabinose 1-dehydrogenase (NADP+) activity(GO:0044103) L-xylulose reductase (NAD+) activity(GO:0044105) 3-ketoglucose-reductase activity(GO:0048258) D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity(GO:0052677) |
| 0.1 | 0.6 | GO:0060698 | endoribonuclease inhibitor activity(GO:0060698) |
| 0.1 | 4.2 | GO:0050694 | galactose 3-O-sulfotransferase activity(GO:0050694) |
| 0.1 | 2.4 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.1 | 4.1 | GO:0001540 | beta-amyloid binding(GO:0001540) |
| 0.1 | 21.4 | GO:0042393 | histone binding(GO:0042393) |
| 0.1 | 4.7 | GO:0003755 | peptidyl-prolyl cis-trans isomerase activity(GO:0003755) |
| 0.1 | 6.1 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.1 | 14.7 | GO:0051015 | actin filament binding(GO:0051015) |
| 0.1 | 1.6 | GO:0001056 | RNA polymerase III activity(GO:0001056) |
| 0.1 | 2.5 | GO:0004707 | MAP kinase activity(GO:0004707) |
| 0.1 | 13.8 | GO:0004930 | G-protein coupled receptor activity(GO:0004930) |
| 0.1 | 1.7 | GO:0008483 | transaminase activity(GO:0008483) |
| 0.1 | 4.7 | GO:0008186 | ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186) |
| 0.1 | 4.5 | GO:0046332 | SMAD binding(GO:0046332) |
| 0.1 | 14.8 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.1 | 1.2 | GO:0042800 | histone methyltransferase activity (H3-K4 specific)(GO:0042800) |
| 0.1 | 3.5 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.1 | 1.8 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 0.1 | 24.0 | GO:0004674 | protein serine/threonine kinase activity(GO:0004674) |
| 0.1 | 1.4 | GO:0018602 | sulfonate dioxygenase activity(GO:0000907) 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity(GO:0018602) procollagen-proline dioxygenase activity(GO:0019798) peptidyl-proline dioxygenase activity(GO:0031543) hypophosphite dioxygenase activity(GO:0034792) gibberellin 2-beta-dioxygenase activity(GO:0045543) C-19 gibberellin 2-beta-dioxygenase activity(GO:0052634) C-20 gibberellin 2-beta-dioxygenase activity(GO:0052635) |
| 0.1 | 0.6 | GO:0017070 | U6 snRNA binding(GO:0017070) |
| 0.0 | 1.7 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.0 | 2.5 | GO:0001104 | RNA polymerase II transcription cofactor activity(GO:0001104) |
| 0.0 | 3.5 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.0 | 3.3 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.0 | 1.0 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.0 | 1.2 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
| 0.0 | 0.6 | GO:0031418 | L-ascorbic acid binding(GO:0031418) |
| 0.0 | 3.3 | GO:0004386 | helicase activity(GO:0004386) |
| 0.0 | 0.3 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
| 0.0 | 0.5 | GO:0008143 | poly(A) binding(GO:0008143) |
| 0.0 | 7.2 | GO:0015631 | tubulin binding(GO:0015631) |
| 0.0 | 0.8 | GO:0044824 | integrase activity(GO:0008907) T/G mismatch-specific endonuclease activity(GO:0043765) retroviral integrase activity(GO:0044823) retroviral 3' processing activity(GO:0044824) |
| 0.0 | 0.5 | GO:0019843 | rRNA binding(GO:0019843) |
| 0.0 | 0.4 | GO:0043425 | bHLH transcription factor binding(GO:0043425) |
| 0.0 | 9.1 | GO:0008270 | zinc ion binding(GO:0008270) |
| 0.0 | 0.6 | GO:0035496 | UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980) O antigen polymerase activity(GO:0008755) lipopolysaccharide-1,6-galactosyltransferase activity(GO:0008921) cellulose synthase activity(GO:0016759) 9-phenanthrol UDP-glucuronosyltransferase activity(GO:0018715) 1-phenanthrol glycosyltransferase activity(GO:0018716) 9-phenanthrol glycosyltransferase activity(GO:0018717) 1,2-dihydroxy-phenanthrene glycosyltransferase activity(GO:0018718) phenanthrol glycosyltransferase activity(GO:0019112) alpha-1,2-galactosyltransferase activity(GO:0031278) dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0033556) endogalactosaminidase activity(GO:0033931) lipopolysaccharide-1,5-galactosyltransferase activity(GO:0035496) dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0042283) inositol phosphoceramide synthase activity(GO:0045140) alpha-(1->3)-fucosyltransferase activity(GO:0046920) indole-3-butyrate beta-glucosyltransferase activity(GO:0052638) salicylic acid glucosyltransferase (ester-forming) activity(GO:0052639) salicylic acid glucosyltransferase (glucoside-forming) activity(GO:0052640) benzoic acid glucosyltransferase activity(GO:0052641) chondroitin hydrolase activity(GO:0052757) dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity(GO:0052824) cytokinin 9-beta-glucosyltransferase activity(GO:0080062) |
