Motif ID: Sp100

Z-value: 2.932


Transcription factors associated with Sp100:

Gene SymbolEntrez IDGene Name
Sp100 ENSMUSG00000026222.10 Sp100

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sp100mm10_v2_chr1_+_85650044_856500520.217.5e-02Click!


Activity profile for motif Sp100.

activity profile for motif Sp100


Sorted Z-values histogram for motif Sp100

Sorted Z-values for motif Sp100



Network of associatons between targets according to the STRING database.



First level regulatory network of Sp100

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_+_3023547 76.437 ENSMUST00000099046.3
 Gm10718
predicted gene 10718
chr9_+_3013140 73.262 ENSMUST00000143083.2
 Gm10721
predicted gene 10721
chr14_-_19418930 65.778 ENSMUST00000177817.1
 Gm21738
predicted gene, 21738
chr9_+_3025417 63.874 ENSMUST00000075573.6
 Gm10717
predicted gene 10717
chr2_-_98667264 59.329 ENSMUST00000099683.1
 Gm10800
predicted gene 10800
chr9_+_3004457 56.471 ENSMUST00000178348.1
 Gm11168
predicted gene 11168
chr9_+_3018753 56.399 ENSMUST00000179272.1
 Gm10719
predicted gene 10719
chr9_+_3017408 55.302 ENSMUST00000099049.3
 Gm10719
predicted gene 10719
chr9_+_3000922 45.216 ENSMUST00000151376.2
 Gm10722
predicted gene 10722
chr9_+_3027439 44.595 ENSMUST00000177875.1
ENSMUST00000179982.1
 Gm10717

predicted gene 10717

chr9_+_3036877 44.026 ENSMUST00000155807.2
 Gm10715
predicted gene 10715
chr9_+_3015654 40.455 ENSMUST00000099050.3
 Gm10720
predicted gene 10720
chr14_+_65806066 29.447 ENSMUST00000139644.1
 Pbk
PDZ binding kinase
chr8_+_94179089 29.219 ENSMUST00000034215.6
 Mt1
metallothionein 1
chr10_-_42583628 28.132 ENSMUST00000019938.4
 Nr2e1
nuclear receptor subfamily 2, group E, member 1
chr3_+_135212557 26.438 ENSMUST00000062893.7
 Cenpe
centromere protein E
chr8_-_4779513 23.316 ENSMUST00000022945.7
 Shcbp1
Shc SH2-domain binding protein 1
chr3_-_88410295 20.537 ENSMUST00000056370.7
 Pmf1
polyamine-modulated factor 1
chr7_+_67647405 18.391 ENSMUST00000032774.8
ENSMUST00000107471.1
 Ttc23

tetratricopeptide repeat domain 23

chr9_-_36726374 18.184 ENSMUST00000172702.2
ENSMUST00000172742.1
ENSMUST00000034625.5
 Chek1


checkpoint kinase 1



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 122 entries
Log-likelihood per target Total log-likelihoodTermDescription
4.2 29.2 GO:0010273 detoxification of copper ion(GO:0010273) cellular response to zinc ion(GO:0071294) stress response to copper ion(GO:1990169)
5.6 28.1 GO:0021764 amygdala development(GO:0021764)
5.3 26.4 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.4 25.2 GO:0070303 negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
0.8 24.8 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.2 20.4 GO:0001578 microtubule bundle formation(GO:0001578)
1.1 19.6 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.1 18.8 GO:0007059 chromosome segregation(GO:0007059)
3.0 18.2 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
2.6 18.2 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.3 17.7 GO:0035307 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
3.5 17.3 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
1.7 16.5 GO:0046036 GTP biosynthetic process(GO:0006183) CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036)
0.1 15.0 GO:0051028 mRNA transport(GO:0051028)
0.2 14.6 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.8 14.4 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.8 14.2 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.8 13.6 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.5 12.2 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
1.5 12.1 GO:0044027 hypermethylation of CpG island(GO:0044027)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 63 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 309.3 GO:0005575 cellular_component(GO:0005575)
2.9 26.4 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.7 22.8 GO:0005721 pericentric heterochromatin(GO:0005721)
0.4 20.8 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
3.4 20.5 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.3 18.2 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.8 17.9 GO:0001741 XY body(GO:0001741)
0.0 17.4 GO:0005925 focal adhesion(GO:0005925)
1.3 17.3 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
4.7 14.2 GO:0034684 integrin alphav-beta5 complex(GO:0034684)
3.4 13.6 GO:0043293 apoptosome(GO:0043293)
0.2 13.2 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.4 13.1 GO:0000788 nuclear nucleosome(GO:0000788)
0.5 12.3 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.3 12.0 GO:0000786 nucleosome(GO:0000786)
0.1 10.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.3 8.7 GO:0035145 exon-exon junction complex(GO:0035145)
0.8 7.8 GO:0045298 tubulin complex(GO:0045298)
0.1 7.8 GO:0005871 kinesin complex(GO:0005871)
0.8 7.3 GO:0061574 ASAP complex(GO:0061574)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 94 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 29.2 GO:0005507 copper ion binding(GO:0005507)
0.4 28.1 GO:0003707 steroid hormone receptor activity(GO:0003707)
6.6 26.4 GO:0043515 kinetochore binding(GO:0043515)
0.6 26.1 GO:0042169 SH2 domain binding(GO:0042169)
0.1 24.0 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.1 21.4 GO:0042393 histone binding(GO:0042393)
0.5 21.0 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
6.1 18.2 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.2 17.7 GO:0005178 integrin binding(GO:0005178)
0.5 17.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.8 16.5 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
1.2 15.7 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 14.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 14.7 GO:0051015 actin filament binding(GO:0051015)
0.1 13.8 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.3 12.7 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.7 12.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
1.1 12.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
1.5 12.1 GO:0051718 DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.5 9.8 GO:0051920 peroxiredoxin activity(GO:0051920)