Motif ID: Sp2

Z-value: 0.517


Transcription factors associated with Sp2:

Gene SymbolEntrez IDGene Name
Sp2 ENSMUSG00000018678.6 Sp2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sp2mm10_v2_chr11_-_96977660_969777110.094.4e-01Click!


Activity profile for motif Sp2.

activity profile for motif Sp2


Sorted Z-values histogram for motif Sp2

Sorted Z-values for motif Sp2



Network of associatons between targets according to the STRING database.



First level regulatory network of Sp2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_87948666 10.073 ENSMUST00000005019.5
 Crabp2
cellular retinoic acid binding protein II
chr12_+_112644828 3.521 ENSMUST00000021728.4
ENSMUST00000109755.3
 Siva1

SIVA1, apoptosis-inducing factor

chr1_+_72824482 2.600 ENSMUST00000047328.4
 Igfbp2
insulin-like growth factor binding protein 2
chr7_-_110061319 2.294 ENSMUST00000098110.2
 AA474408
expressed sequence AA474408
chr17_+_23679363 2.093 ENSMUST00000024699.2
 Cldn6
claudin 6
chrX_-_48034842 1.997 ENSMUST00000039026.7
 Apln
apelin
chr2_-_92370999 1.985 ENSMUST00000176810.1
ENSMUST00000090582.4
 Gyltl1b

glycosyltransferase-like 1B

chr4_+_46450892 1.963 ENSMUST00000102926.4
 Anp32b
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chrX_-_133688978 1.947 ENSMUST00000149154.1
ENSMUST00000167944.1
 Pcdh19

protocadherin 19

chr12_+_112678803 1.928 ENSMUST00000174780.1
ENSMUST00000169593.1
ENSMUST00000173942.1
 Zbtb42


zinc finger and BTB domain containing 42


chr2_-_120154600 1.879 ENSMUST00000028755.7
 Ehd4
EH-domain containing 4
chr2_+_38339258 1.875 ENSMUST00000143783.2
 Lhx2
LIM homeobox protein 2
chr1_+_131962941 1.869 ENSMUST00000177943.1
 Slc45a3
solute carrier family 45, member 3
chr4_+_3938888 1.838 ENSMUST00000121110.1
ENSMUST00000108386.1
ENSMUST00000149544.1
 Chchd7


coiled-coil-helix-coiled-coil-helix domain containing 7


chr17_-_70851189 1.813 ENSMUST00000059775.8
 Tgif1
TGFB-induced factor homeobox 1
chr6_-_82774448 1.811 ENSMUST00000000642.4
 Hk2
hexokinase 2
chr18_+_82914632 1.796 ENSMUST00000071233.6
 Zfp516
zinc finger protein 516
chr2_-_92371039 1.774 ENSMUST00000068586.6
 Gyltl1b
glycosyltransferase-like 1B
chr4_-_117133953 1.681 ENSMUST00000076859.5
 Plk3
polo-like kinase 3
chr4_+_108579445 1.680 ENSMUST00000102744.3
 Orc1
origin recognition complex, subunit 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 218 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.9 11.1 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.4 5.4 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.2 3.5 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 3.4 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.2 2.8 GO:0002227 innate immune response in mucosa(GO:0002227)
0.9 2.7 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.9 2.6 GO:0097402 neuroblast migration(GO:0097402)
0.3 2.5 GO:1901030 positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901030)
0.2 2.5 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 2.5 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.8 2.4 GO:0000087 mitotic M phase(GO:0000087)
0.3 2.2 GO:0045989 positive regulation of striated muscle contraction(GO:0045989)
0.3 2.1 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 2.1 GO:0043966 histone H3 acetylation(GO:0043966)
0.3 2.0 GO:0031652 positive regulation of heat generation(GO:0031652)
0.6 1.9 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.3 1.9 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.3 1.9 GO:1902416 positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216)
0.2 1.9 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1 1.9 GO:0006907 pinocytosis(GO:0006907)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 101 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 23.5 GO:0070062 extracellular exosome(GO:0070062)
0.0 3.6 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 3.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 3.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 3.0 GO:0072562 blood microparticle(GO:0072562)
0.0 2.6 GO:0005840 ribosome(GO:0005840)
0.4 2.3 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 2.3 GO:0045120 pronucleus(GO:0045120)
0.0 2.2 GO:0031513 nonmotile primary cilium(GO:0031513)
0.1 2.1 GO:0002102 podosome(GO:0002102)
0.1 2.0 GO:0035145 exon-exon junction complex(GO:0035145)
0.2 1.7 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 1.7 GO:0000776 kinetochore(GO:0000776)
0.5 1.6 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.4 1.6 GO:0090537 CERF complex(GO:0090537)
0.1 1.6 GO:0034719 SMN-Sm protein complex(GO:0034719)
0.1 1.6 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 1.6 GO:0000922 spindle pole(GO:0000922)
0.3 1.5 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 1.5 GO:0046658 anchored component of plasma membrane(GO:0046658)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 141 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.7 10.1 GO:0019841 retinol binding(GO:0019841)
0.0 9.2 GO:0003735 structural constituent of ribosome(GO:0003735)
1.1 5.4 GO:0018121 imidazoleglycerol-phosphate synthase activity(GO:0000107) NAD(P)-cysteine ADP-ribosyltransferase activity(GO:0018071) NAD(P)-asparagine ADP-ribosyltransferase activity(GO:0018121) NAD(P)-serine ADP-ribosyltransferase activity(GO:0018127) 7-cyano-7-deazaguanine tRNA-ribosyltransferase activity(GO:0043867) purine deoxyribosyltransferase activity(GO:0044102)
0.0 5.3 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 4.1 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 2.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.2 2.7 GO:0001848 complement binding(GO:0001848)
0.3 2.6 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 2.6 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 2.5 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 2.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.2 2.1 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 2.1 GO:0033613 activating transcription factor binding(GO:0033613)
0.1 2.0 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.6 1.9 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.1 1.9 GO:0070410 co-SMAD binding(GO:0070410)
0.4 1.8 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.2 1.7 GO:0001618 virus receptor activity(GO:0001618)
0.1 1.7 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 1.7 GO:0016749 N-succinyltransferase activity(GO:0016749)