Motif ID: Stat5a

Z-value: 1.319


Transcription factors associated with Stat5a:

Gene SymbolEntrez IDGene Name
Stat5a ENSMUSG00000004043.8 Stat5a



Activity profile for motif Stat5a.

activity profile for motif Stat5a


Sorted Z-values histogram for motif Stat5a

Sorted Z-values for motif Stat5a



Network of associatons between targets according to the STRING database.



First level regulatory network of Stat5a

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_-_42583628 20.570 ENSMUST00000019938.4
Nr2e1
nuclear receptor subfamily 2, group E, member 1
chr10_+_84838143 11.438 ENSMUST00000095388.4
Rfx4
regulatory factor X, 4 (influences HLA class II expression)
chr11_-_55419898 11.310 ENSMUST00000108858.1
ENSMUST00000141530.1
Sparc

secreted acidic cysteine rich glycoprotein

chr7_+_88278085 10.464 ENSMUST00000032779.5
ENSMUST00000128791.1
Ctsc

cathepsin C

chr9_+_92250039 9.908 ENSMUST00000093801.3
Plscr1
phospholipid scramblase 1
chr15_-_103366763 9.814 ENSMUST00000023128.6
Itga5
integrin alpha 5 (fibronectin receptor alpha)
chr17_-_25797032 9.563 ENSMUST00000165838.1
ENSMUST00000002344.6
Metrn

meteorin, glial cell differentiation regulator

chr16_+_33829624 9.510 ENSMUST00000115028.3
Itgb5
integrin beta 5
chr8_+_94179089 9.174 ENSMUST00000034215.6
Mt1
metallothionein 1
chr11_+_98412461 9.046 ENSMUST00000058295.5
Erbb2
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
chr2_-_80447625 9.030 ENSMUST00000028389.3
Frzb
frizzled-related protein
chr6_+_4755327 8.475 ENSMUST00000176551.1
Peg10
paternally expressed 10
chr1_+_90203980 8.440 ENSMUST00000065587.4
ENSMUST00000159654.1
Ackr3

atypical chemokine receptor 3

chr3_-_25212720 8.299 ENSMUST00000091289.3
Gm10259
predicted pseudogene 10259
chr7_+_107567445 8.213 ENSMUST00000120990.1
Olfml1
olfactomedin-like 1
chr6_+_121636173 8.092 ENSMUST00000032203.7
A2m
alpha-2-macroglobulin
chr2_+_5845243 8.070 ENSMUST00000127116.1
Nudt5
nudix (nucleoside diphosphate linked moiety X)-type motif 5
chr10_+_22158566 8.063 ENSMUST00000181645.1
ENSMUST00000105522.2
Raet1e
H60b
retinoic acid early transcript 1E
histocompatibility 60b
chr7_-_103853199 7.894 ENSMUST00000033229.3
Hbb-y
hemoglobin Y, beta-like embryonic chain
chr2_+_52038005 7.741 ENSMUST00000065927.5
Tnfaip6
tumor necrosis factor alpha induced protein 6

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 466 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.0 25.6 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
3.8 19.1 GO:0021764 amygdala development(GO:0021764)
1.1 18.9 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
1.0 15.3 GO:0009191 ribonucleoside diphosphate catabolic process(GO:0009191)
1.0 14.3 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.7 12.4 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
3.1 12.2 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
2.4 12.0 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.6 11.2 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
2.1 10.5 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
1.7 10.3 GO:0071294 cellular response to zinc ion(GO:0071294)
3.3 9.9 GO:0010911 regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912) phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
3.3 9.9 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.8 9.9 GO:0007076 mitotic chromosome condensation(GO:0007076)
1.1 9.8 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
1.1 9.7 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.2 9.7 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.1 9.5 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.2 9.4 GO:0051384 response to glucocorticoid(GO:0051384)
1.0 9.1 GO:0097421 liver regeneration(GO:0097421)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 210 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 46.8 GO:0005615 extracellular space(GO:0005615)
0.1 30.8 GO:0031012 extracellular matrix(GO:0031012)
0.5 24.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.3 22.9 GO:0072562 blood microparticle(GO:0072562)
0.1 21.6 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.9 14.5 GO:0005614 interstitial matrix(GO:0005614)
0.1 13.3 GO:0015934 large ribosomal subunit(GO:0015934)
0.7 13.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.5 12.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
2.8 11.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
2.6 10.5 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.5 10.3 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.9 10.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 9.9 GO:0005901 caveola(GO:0005901)
0.2 9.6 GO:0000791 euchromatin(GO:0000791)
3.2 9.5 GO:0034684 integrin alphav-beta5 complex(GO:0034684)
1.1 9.0 GO:0005818 aster(GO:0005818)
0.7 8.9 GO:0043219 lateral loop(GO:0043219)
2.7 8.1 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
1.0 7.9 GO:0005833 hemoglobin complex(GO:0005833)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 302 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 22.2 GO:0050840 extracellular matrix binding(GO:0050840)
0.3 20.9 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.1 18.6 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
5.5 16.5 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.3 15.5 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.7 15.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
1.6 12.7 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.7 10.9 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
1.2 10.5 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.6 10.4 GO:0005540 hyaluronic acid binding(GO:0005540)
1.2 9.9 GO:0042609 CD4 receptor binding(GO:0042609)
0.5 9.7 GO:0001784 phosphotyrosine binding(GO:0001784)
1.1 9.0 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 9.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.7 8.9 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.1 8.9 GO:0008201 heparin binding(GO:0008201)
0.9 8.6 GO:0042301 phosphate ion binding(GO:0042301)
1.7 8.5 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.4 8.0 GO:0004602 glutathione peroxidase activity(GO:0004602)
2.0 7.9 GO:0031721 hemoglobin alpha binding(GO:0031721)