Motif ID: Stat6

Z-value: 1.089


Transcription factors associated with Stat6:

Gene SymbolEntrez IDGene Name
Stat6 ENSMUSG00000002147.12 Stat6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Stat6mm10_v2_chr10_+_127642975_1276430340.326.1e-03Click!


Activity profile for motif Stat6.

activity profile for motif Stat6


Sorted Z-values histogram for motif Stat6

Sorted Z-values for motif Stat6



Network of associatons between targets according to the STRING database.



First level regulatory network of Stat6

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_136143497 17.318 ENSMUST00000008016.2
Id3
inhibitor of DNA binding 3
chr9_-_70421533 14.639 ENSMUST00000034742.6
Ccnb2
cyclin B2
chr11_-_55419898 13.215 ENSMUST00000108858.1
ENSMUST00000141530.1
Sparc

secreted acidic cysteine rich glycoprotein

chr18_+_50053282 12.841 ENSMUST00000148159.2
Tnfaip8
tumor necrosis factor, alpha-induced protein 8
chr11_-_102579461 12.789 ENSMUST00000107081.1
Gm11627
predicted gene 11627
chr1_-_120121030 11.492 ENSMUST00000027634.6
Dbi
diazepam binding inhibitor
chr18_-_15403680 11.325 ENSMUST00000079081.6
Aqp4
aquaporin 4
chr15_-_82244716 10.966 ENSMUST00000089155.4
ENSMUST00000089157.3
Cenpm

centromere protein M

chr2_-_113848655 10.395 ENSMUST00000102545.1
ENSMUST00000110948.1
Arhgap11a

Rho GTPase activating protein 11A

chr2_-_113848601 10.110 ENSMUST00000110949.2
Arhgap11a
Rho GTPase activating protein 11A
chr1_+_146497614 9.865 ENSMUST00000132847.1
ENSMUST00000166814.1
Brinp3

bone morphogenetic protein/retinoic acid inducible neural specific 3

chr10_-_78591945 9.733 ENSMUST00000040580.6
Syde1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr17_-_89910449 8.945 ENSMUST00000086423.4
Gm10184
predicted pseudogene 10184
chr2_+_163225363 8.732 ENSMUST00000099110.3
ENSMUST00000165937.1
Tox2

TOX high mobility group box family member 2

chr4_+_116708467 8.695 ENSMUST00000030452.6
Ccdc163
coiled-coil domain containing 163
chr2_-_51972990 8.017 ENSMUST00000145481.1
ENSMUST00000112705.2
Nmi

N-myc (and STAT) interactor

chr15_+_32920723 7.877 ENSMUST00000022871.5
Sdc2
syndecan 2
chr14_-_21989475 7.819 ENSMUST00000043409.7
Zfp503
zinc finger protein 503
chr2_-_147186389 7.714 ENSMUST00000109970.3
ENSMUST00000067075.5
Nkx2-2

NK2 homeobox 2

chr11_-_60220550 7.523 ENSMUST00000020846.1
Srebf1
sterol regulatory element binding transcription factor 1
chr4_+_116708571 7.435 ENSMUST00000106462.2
ENSMUST00000138305.1
ENSMUST00000125671.1
ENSMUST00000130828.1
Ccdc163



coiled-coil domain containing 163



chr6_-_125313844 7.336 ENSMUST00000032489.7
Ltbr
lymphotoxin B receptor
chr7_+_107567445 6.922 ENSMUST00000120990.1
Olfml1
olfactomedin-like 1
chr6_+_66896397 6.906 ENSMUST00000043148.6
ENSMUST00000114228.1
ENSMUST00000114227.1
ENSMUST00000114226.1
ENSMUST00000114225.1
ENSMUST00000114224.1
Gng12





guanine nucleotide binding protein (G protein), gamma 12





chr15_+_25773985 6.744 ENSMUST00000125667.1
Myo10
myosin X
chr2_+_30077684 6.700 ENSMUST00000125346.1
Pkn3
protein kinase N3
chr2_+_70562854 6.690 ENSMUST00000130998.1
Gad1
glutamate decarboxylase 1
chr7_-_38227975 6.528 ENSMUST00000098513.4
Plekhf1
pleckstrin homology domain containing, family F (with FYVE domain) member 1
chr2_+_70563435 6.419 ENSMUST00000123330.1
Gad1
glutamate decarboxylase 1
chr4_+_116708687 6.288 ENSMUST00000135499.1
Ccdc163
coiled-coil domain containing 163
chr2_-_101628930 6.166 ENSMUST00000099682.2
B230118H07Rik
RIKEN cDNA B230118H07 gene
chr4_+_116708624 6.163 ENSMUST00000106463.1
Ccdc163
coiled-coil domain containing 163
chr7_-_126800354 6.098 ENSMUST00000106348.1
Aldoa
aldolase A, fructose-bisphosphate
chr2_-_73453918 6.069 ENSMUST00000102679.1
Wipf1
WAS/WASL interacting protein family, member 1
chr9_+_44066993 5.622 ENSMUST00000034508.7
Usp2
ubiquitin specific peptidase 2
chr1_+_146495621 5.510 ENSMUST00000074622.4
Brinp3
bone morphogenetic protein/retinoic acid inducible neural specific 3
chr2_-_125723387 5.426 ENSMUST00000042246.7
Shc4
SHC (Src homology 2 domain containing) family, member 4
chr7_-_126800036 5.362 ENSMUST00000133514.1
ENSMUST00000151137.1
Aldoa

aldolase A, fructose-bisphosphate

chr16_-_23890805 5.264 ENSMUST00000004480.3
Sst
somatostatin
chr2_-_101628958 5.232 ENSMUST00000111231.3
B230118H07Rik
RIKEN cDNA B230118H07 gene
chr13_+_99100698 5.098 ENSMUST00000181742.1
Gm807
predicted gene 807
chr7_+_101348061 5.055 ENSMUST00000107010.2
Arap1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr9_+_44067072 4.741 ENSMUST00000177054.1
Usp2
ubiquitin specific peptidase 2
chr6_+_66896480 4.740 ENSMUST00000114222.1
Gng12
guanine nucleotide binding protein (G protein), gamma 12
chr3_+_97032416 4.671 ENSMUST00000132256.1
ENSMUST00000072600.6
Gja5

gap junction protein, alpha 5

chr1_+_134182404 4.413 ENSMUST00000153856.1
ENSMUST00000082060.3
ENSMUST00000133701.1
ENSMUST00000132873.1
Chi3l1



chitinase 3-like 1



chrX_-_53269786 4.345 ENSMUST00000114841.1
ENSMUST00000071023.5
Fam122b

family with sequence similarity 122, member B

chr4_+_32983008 4.203 ENSMUST00000098190.3
ENSMUST00000029946.7
Rragd

Ras-related GTP binding D

chr3_-_86548268 3.997 ENSMUST00000077524.3
Mab21l2
mab-21-like 2 (C. elegans)
chr18_+_24205937 3.864 ENSMUST00000164998.1
Galnt1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1
chr1_+_134182150 3.801 ENSMUST00000156873.1
Chi3l1
chitinase 3-like 1
chr1_+_59516264 3.571 ENSMUST00000114243.1
Gm973
predicted gene 973
chr6_-_4086914 3.506 ENSMUST00000049166.4
Bet1
blocked early in transport 1 homolog (S. cerevisiae)
chr1_-_125912160 3.486 ENSMUST00000159417.1
Lypd1
Ly6/Plaur domain containing 1
chr17_+_28232723 3.382 ENSMUST00000002320.8
Ppard
peroxisome proliferator activator receptor delta
chr9_-_35176039 3.373 ENSMUST00000119847.1
ENSMUST00000034539.5
Dcps

decapping enzyme, scavenger

chr11_-_11890394 3.301 ENSMUST00000109659.2
Ddc
dopa decarboxylase
chr1_+_156035392 3.242 ENSMUST00000111757.3
Tor1aip2
torsin A interacting protein 2
chr2_+_79635416 3.115 ENSMUST00000111788.1
Ssfa2
sperm specific antigen 2
chr3_+_14641722 3.028 ENSMUST00000029071.8
Car13
carbonic anhydrase 13
chr2_+_79635352 3.026 ENSMUST00000111785.2
Ssfa2
sperm specific antigen 2
chr1_-_44118757 2.990 ENSMUST00000027213.7
ENSMUST00000065767.2
Kdelc1

KDEL (Lys-Asp-Glu-Leu) containing 1

chr13_-_41358990 2.797 ENSMUST00000163623.1
Nedd9
neural precursor cell expressed, developmentally down-regulated gene 9
chr1_+_88227005 2.772 ENSMUST00000061013.6
ENSMUST00000113130.1
Mroh2a

maestro heat-like repeat family member 2A

chr4_+_120666562 2.618 ENSMUST00000094814.4
Cited4
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
chr4_-_116708312 2.586 ENSMUST00000030453.4
Mmachc
methylmalonic aciduria cblC type, with homocystinuria
chr14_+_75845093 2.550 ENSMUST00000110894.2
Tpt1
tumor protein, translationally-controlled 1
chr11_-_11890368 2.446 ENSMUST00000155690.1
Ddc
dopa decarboxylase
chr5_+_139543889 2.340 ENSMUST00000174792.1
ENSMUST00000031523.8
Uncx

UNC homeobox

chr15_-_81926148 2.309 ENSMUST00000023113.5
Polr3h
polymerase (RNA) III (DNA directed) polypeptide H
chr10_+_97479470 2.251 ENSMUST00000105287.3
Dcn
decorin
chr15_+_59648350 2.242 ENSMUST00000067543.6
Trib1
tribbles homolog 1 (Drosophila)
chr5_+_31054821 2.197 ENSMUST00000174367.1
ENSMUST00000170329.1
ENSMUST00000031049.6
Cad


carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase


chr5_+_31054766 2.144 ENSMUST00000013773.5
ENSMUST00000114646.1
Cad

carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase

chr3_-_8923796 2.119 ENSMUST00000042148.5
Mrps28
mitochondrial ribosomal protein S28
chr9_+_120929216 2.078 ENSMUST00000130466.1
Ctnnb1
catenin (cadherin associated protein), beta 1
chr7_-_44816586 2.007 ENSMUST00000047356.8
Atf5
activating transcription factor 5
chr12_-_57197311 1.936 ENSMUST00000044634.5
Slc25a21
solute carrier family 25 (mitochondrial oxodicarboxylate carrier), member 21
chr1_-_175625580 1.798 ENSMUST00000027810.7
Fh1
fumarate hydratase 1
chr11_+_108587077 1.797 ENSMUST00000146912.2
Cep112
centrosomal protein 112
chr10_+_81070035 1.702 ENSMUST00000005057.6
Thop1
thimet oligopeptidase 1
chr3_+_67892189 1.700 ENSMUST00000063263.3
Iqcj
IQ motif containing J
chr15_+_57694651 1.604 ENSMUST00000096430.4
Zhx2
zinc fingers and homeoboxes 2
chr16_-_56712825 1.561 ENSMUST00000136394.1
Tfg
Trk-fused gene
chr15_+_6422240 1.516 ENSMUST00000163082.1
Dab2
disabled 2, mitogen-responsive phosphoprotein
chr7_-_90129339 1.515 ENSMUST00000181189.1
2310010J17Rik
RIKEN cDNA 2310010J17 gene
chr8_-_47990535 1.436 ENSMUST00000057561.7
Wwc2
WW, C2 and coiled-coil domain containing 2
chr1_-_125913101 1.382 ENSMUST00000161361.1
Lypd1
Ly6/Plaur domain containing 1
chr14_-_65425453 1.325 ENSMUST00000059339.5
Pnoc
prepronociceptin
chr5_+_114786045 1.288 ENSMUST00000137519.1
Ankrd13a
ankyrin repeat domain 13a
chr3_-_141931523 1.220 ENSMUST00000106232.1
Bmpr1b
bone morphogenetic protein receptor, type 1B
chr15_-_33405976 1.204 ENSMUST00000079057.6
1700084J12Rik
RIKEN cDNA 1700084J12 gene
chr14_+_20703027 1.166 ENSMUST00000071215.3
Chchd1
coiled-coil-helix-coiled-coil-helix domain containing 1
chr8_-_106573461 1.018 ENSMUST00000073722.5
Gm10073
predicted pseudogene 10073
chr2_-_30093642 1.007 ENSMUST00000102865.4
Zdhhc12
zinc finger, DHHC domain containing 12
chr1_-_144177259 1.000 ENSMUST00000111941.1
ENSMUST00000052375.1
Rgs13

regulator of G-protein signaling 13

chr5_-_24445166 0.837 ENSMUST00000115043.1
ENSMUST00000115041.1
Fastk

Fas-activated serine/threonine kinase

chr5_-_106574706 0.707 ENSMUST00000131029.1
ENSMUST00000124394.2
RP24-421H18.1

RP24-421H18.1

chr18_-_36726730 0.696 ENSMUST00000061829.6
Cd14
CD14 antigen
chr11_-_106920359 0.673 ENSMUST00000167787.1
ENSMUST00000092517.2
Smurf2

SMAD specific E3 ubiquitin protein ligase 2

chr7_+_28350652 0.646 ENSMUST00000082134.4
Rps16
ribosomal protein S16
chr1_-_60566708 0.634 ENSMUST00000027168.5
ENSMUST00000090293.4
ENSMUST00000140485.1
Raph1


Ras association (RalGDS/AF-6) and pleckstrin homology domains 1


chr13_+_43785107 0.628 ENSMUST00000015540.2
Cd83
CD83 antigen
chr11_+_78188422 0.618 ENSMUST00000002128.7
ENSMUST00000150941.1
Rab34

RAB34, member of RAS oncogene family

chr2_-_144550777 0.617 ENSMUST00000028915.5
Rbbp9
retinoblastoma binding protein 9
chr2_-_30093607 0.615 ENSMUST00000081838.6
Zdhhc12
zinc finger, DHHC domain containing 12
chr14_-_55758458 0.612 ENSMUST00000001497.7
Cideb
cell death-inducing DNA fragmentation factor, alpha subunit-like effector B
chrX_-_140956675 0.612 ENSMUST00000033805.8
ENSMUST00000112978.1
Psmd10

proteasome (prosome, macropain) 26S subunit, non-ATPase, 10

chr17_+_29090969 0.544 ENSMUST00000119901.1
Cdkn1a
cyclin-dependent kinase inhibitor 1A (P21)
chr11_+_101245996 0.539 ENSMUST00000129680.1
Ramp2
receptor (calcitonin) activity modifying protein 2
chr9_+_75037838 0.483 ENSMUST00000169188.1
Arpp19
cAMP-regulated phosphoprotein 19
chr7_+_44816088 0.433 ENSMUST00000057195.9
ENSMUST00000107891.1
Nup62

nucleoporin 62

chr10_-_128626464 0.390 ENSMUST00000026420.5
Rps26
ribosomal protein S26
chr13_-_115090123 0.389 ENSMUST00000109226.3
Pelo
pelota homolog (Drosophila)
chr7_+_140882430 0.371 ENSMUST00000164681.1
ENSMUST00000163610.1
Psmd13

proteasome (prosome, macropain) 26S subunit, non-ATPase, 13

chr12_+_37108533 0.360 ENSMUST00000041183.5
Meox2
mesenchyme homeobox 2
chr7_+_81213567 0.338 ENSMUST00000026672.7
Pde8a
phosphodiesterase 8A
chrX_-_140543177 0.319 ENSMUST00000055738.5
Tsc22d3
TSC22 domain family, member 3
chr2_-_14056029 0.298 ENSMUST00000074854.7
Ptpla
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member a
chr5_-_24445254 0.288 ENSMUST00000030800.6
Fastk
Fas-activated serine/threonine kinase
chr9_+_75037809 0.280 ENSMUST00000167885.1
Arpp19
cAMP-regulated phosphoprotein 19
chrX_+_7842056 0.269 ENSMUST00000115667.3
ENSMUST00000115668.3
ENSMUST00000115665.1
Otud5


OTU domain containing 5


chr11_-_78183551 0.266 ENSMUST00000102483.4
Rpl23a
ribosomal protein L23A
chr1_+_156035705 0.240 ENSMUST00000111754.2
ENSMUST00000133152.1
Tor1aip2

torsin A interacting protein 2

chr2_-_14055963 0.187 ENSMUST00000091429.5
ENSMUST00000114753.1
Ptpla

protein tyrosine phosphatase-like (proline instead of catalytic arginine), member a

chr6_-_71440623 0.155 ENSMUST00000002292.8
Rmnd5a
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr9_+_86743641 0.141 ENSMUST00000179574.1
Prss35
protease, serine, 35
chr9_+_75051977 0.121 ENSMUST00000170310.1
ENSMUST00000166549.1
Arpp19

cAMP-regulated phosphoprotein 19

chr14_+_79587691 0.114 ENSMUST00000054908.8
Sugt1
SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)
chr12_-_59219725 0.089 ENSMUST00000043204.7
Fbxo33
F-box protein 33
chr11_-_106779483 0.052 ENSMUST00000021060.5
Polg2
polymerase (DNA directed), gamma 2, accessory subunit
chr11_+_84880308 0.026 ENSMUST00000020837.6
Myo19
myosin XIX
chr1_-_126738167 0.009 ENSMUST00000160693.1
Nckap5
NCK-associated protein 5

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 8.0 GO:1902524 negative regulation of interferon-alpha production(GO:0032687) interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) negative regulation of interferon-beta biosynthetic process(GO:0045358) positive regulation of protein K48-linked ubiquitination(GO:1902524)
2.6 7.8 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
2.6 7.7 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
2.3 11.5 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
2.3 11.3 GO:0070295 renal water absorption(GO:0070295)
1.9 13.1 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
1.6 4.7 GO:0086017 renin secretion into blood stream(GO:0002001) cell communication by chemical coupling(GO:0010643) Purkinje myocyte action potential(GO:0086017) regulation of renin secretion into blood stream(GO:1900133)
1.2 9.7 GO:0016081 synaptic vesicle docking(GO:0016081)
1.1 11.5 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
1.1 4.3 GO:0006526 arginine biosynthetic process(GO:0006526)
1.0 3.9 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
1.0 5.7 GO:0098700 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700)
0.9 7.5 GO:0003062 regulation of heart rate by chemical signal(GO:0003062)
0.8 3.4 GO:0006776 vitamin A metabolic process(GO:0006776) positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.7 2.2 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.7 0.7 GO:0071220 response to bacterial lipoprotein(GO:0032493) response to bacterial lipopeptide(GO:0070339) cellular response to bacterial lipoprotein(GO:0071220) cellular response to bacterial lipopeptide(GO:0071221) response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726)
0.7 2.1 GO:0060423 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023) negative regulation of mitotic cell cycle, embryonic(GO:0045976) foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) positive regulation of epithelial cell proliferation involved in prostate gland development(GO:0060769) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901963) regulation of histone demethylase activity (H3-K4 specific)(GO:1904173)
0.7 10.7 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.7 17.3 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.6 2.5 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.6 1.8 GO:0006106 fumarate metabolic process(GO:0006106)
0.5 7.3 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.4 2.6 GO:0009235 cobalamin metabolic process(GO:0009235)
0.4 2.3 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.3 3.4 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.3 12.5 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.3 2.3 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.3 3.5 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.3 15.4 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.3 1.2 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.3 6.1 GO:0051127 positive regulation of actin nucleation(GO:0051127)
0.3 1.5 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.3 2.3 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.3 1.4 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.3 12.5 GO:0043029 T cell homeostasis(GO:0043029)
0.3 3.5 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.2 0.6 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.2 12.8 GO:0050830 defense response to Gram-positive bacterium(GO:0050830)
0.2 4.9 GO:1903077 negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.2 11.8 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.2 0.7 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.2 4.0 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.1 4.2 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.1 6.5 GO:0007032 endosome organization(GO:0007032)
0.1 2.0 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.1 0.5 GO:0070831 basement membrane assembly(GO:0070831)
0.1 0.6 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.1 0.4 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.1 3.0 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 0.5 GO:0090399 replicative senescence(GO:0090399)
0.1 7.9 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
0.1 0.6 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.1 1.6 GO:0018345 protein palmitoylation(GO:0018345)
0.0 1.8 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.4 GO:0007379 segment specification(GO:0007379)
0.0 1.3 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.1 GO:0052428 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.0 2.6 GO:0043627 response to estrogen(GO:0043627)
0.0 6.7 GO:0010631 epithelial cell migration(GO:0010631)
0.0 1.6 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.0 3.0 GO:0006664 glycolipid metabolic process(GO:0006664) liposaccharide metabolic process(GO:1903509)
0.0 0.8 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.4 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.4 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.0 0.6 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 1.0 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0 0.6 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 3.4 GO:0048863 stem cell differentiation(GO:0048863)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 13.2 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.8 4.2 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.8 11.5 GO:0035686 sperm fibrous sheath(GO:0035686)
0.5 9.7 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.4 11.5 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.4 1.5 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.3 13.1 GO:0048786 presynaptic active zone(GO:0048786)
0.3 4.7 GO:0005922 connexon complex(GO:0005922)
0.3 2.1 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.3 2.5 GO:0045298 tubulin complex(GO:0045298)
0.2 11.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.2 0.5 GO:0070557 PCNA-p21 complex(GO:0070557)
0.2 11.3 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.7 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 2.3 GO:0098644 complex of collagen trimers(GO:0098644)
0.1 1.8 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.1 2.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 5.3 GO:0016459 myosin complex(GO:0016459)
0.1 2.8 GO:0000922 spindle pole(GO:0000922)
0.1 3.5 GO:0005801 cis-Golgi network(GO:0005801)
0.1 11.0 GO:0000776 kinetochore(GO:0000776)
0.1 2.1 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 0.4 GO:0044613 nuclear pore central transport channel(GO:0044613) Flemming body(GO:0090543)
0.1 3.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.6 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 26.6 GO:0005813 centrosome(GO:0005813)
0.0 0.4 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 5.3 GO:0005884 actin filament(GO:0005884)
0.0 1.7 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 5.1 GO:0005802 trans-Golgi network(GO:0005802)
0.0 1.0 GO:0022627 small ribosomal subunit(GO:0015935) cytosolic small ribosomal subunit(GO:0022627)
0.0 0.3 GO:0031932 TORC2 complex(GO:0031932)
0.0 7.8 GO:0005768 endosome(GO:0005768)
0.0 0.6 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 31.0 GO:0005654 nucleoplasm(GO:0005654)
0.0 1.9 GO:0000790 nuclear chromatin(GO:0000790)
0.0 0.6 GO:0005811 lipid particle(GO:0005811)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 11.5 GO:0030156 benzodiazepine receptor binding(GO:0030156)
1.9 11.5 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
1.9 13.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
1.6 11.3 GO:0015288 porin activity(GO:0015288)
1.4 5.7 GO:0036468 aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468)
1.2 11.6 GO:0042301 phosphate ion binding(GO:0042301)
1.1 3.4 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
1.1 4.3 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.9 4.7 GO:0071253 connexin binding(GO:0071253)
0.8 3.4 GO:0004954 icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955)
0.6 4.9 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.4 7.3 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.4 2.6 GO:0031419 cobalamin binding(GO:0031419)
0.3 12.8 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.3 15.5 GO:0050840 extracellular matrix binding(GO:0050840)
0.3 2.1 GO:1990188 euchromatin binding(GO:1990188)
0.3 10.7 GO:0005504 fatty acid binding(GO:0005504)
0.3 10.9 GO:0030332 cyclin binding(GO:0030332)
0.3 1.5 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.3 3.0 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.2 2.8 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.2 3.9 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.2 8.1 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.2 6.7 GO:0004697 protein kinase C activity(GO:0004697)
0.2 0.7 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.1 1.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 3.5 GO:0001671 ATPase activator activity(GO:0001671)
0.1 6.7 GO:0030507 spectrin binding(GO:0030507)
0.1 0.4 GO:0051425 PTB domain binding(GO:0051425)
0.1 2.3 GO:0001056 RNA polymerase III activity(GO:0001056)
0.1 6.6 GO:0005179 hormone activity(GO:0005179)
0.1 5.4 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.1 1.2 GO:0031702 angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.1 10.8 GO:0051015 actin filament binding(GO:0051015)
0.1 0.9 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 1.6 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.1 0.3 GO:0043426 MRF binding(GO:0043426)
0.0 2.6 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 3.0 GO:0046527 glucosyltransferase activity(GO:0046527)
0.0 12.7 GO:0005096 GTPase activator activity(GO:0005096)
0.0 5.3 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 3.5 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.6 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.5 GO:0015026 coreceptor activity(GO:0015026)
0.0 7.5 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 1.8 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.0 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.7 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 1.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.3 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.8 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 1.4 GO:0032947 protein complex scaffold(GO:0032947)
0.0 2.0 GO:0031072 heat shock protein binding(GO:0031072)
0.0 0.6 GO:0052771 coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771)
0.0 3.0 GO:0003735 structural constituent of ribosome(GO:0003735)