Motif ID: Tbp

Z-value: 2.406


Transcription factors associated with Tbp:

Gene SymbolEntrez IDGene Name
Tbp ENSMUSG00000014767.10 Tbp

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tbpmm10_v2_chr17_+_15499888_15499960-0.371.7e-03Click!


Activity profile for motif Tbp.

activity profile for motif Tbp


Sorted Z-values histogram for motif Tbp

Sorted Z-values for motif Tbp



Network of associatons between targets according to the STRING database.



First level regulatory network of Tbp

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_87948666 31.186 ENSMUST00000005019.5
 Crabp2
cellular retinoic acid binding protein II
chr7_-_103853199 29.251 ENSMUST00000033229.3
 Hbb-y
hemoglobin Y, beta-like embryonic chain
chr16_+_91225550 26.834 ENSMUST00000035608.8
 Olig2
oligodendrocyte transcription factor 2
chr3_-_145649970 26.631 ENSMUST00000029846.3
 Cyr61
cysteine rich protein 61
chr4_+_136143497 22.657 ENSMUST00000008016.2
 Id3
inhibitor of DNA binding 3
chr8_+_94179089 22.254 ENSMUST00000034215.6
 Mt1
metallothionein 1
chr7_-_103843154 16.960 ENSMUST00000063957.4
 Hbb-bh1
hemoglobin Z, beta-like embryonic chain
chr6_+_4747306 16.399 ENSMUST00000175823.1
ENSMUST00000176204.1
ENSMUST00000166678.1
 Peg10


paternally expressed 10


chr2_+_13573927 16.038 ENSMUST00000141365.1
ENSMUST00000028062.2
 Vim

vimentin

chr11_-_99024179 15.650 ENSMUST00000068031.7
 Top2a
topoisomerase (DNA) II alpha
chr5_-_77115145 15.402 ENSMUST00000081964.5
 Hopx
HOP homeobox
chr17_-_24251382 15.319 ENSMUST00000115390.3
 Ccnf
cyclin F
chrX_-_162159717 14.625 ENSMUST00000087085.3
 Nhs
Nance-Horan syndrome (human)
chr2_+_152736244 14.139 ENSMUST00000038368.8
ENSMUST00000109824.1
 Id1

inhibitor of DNA binding 1

chr8_+_12395287 13.997 ENSMUST00000180353.1
 Sox1
SRY-box containing gene 1
chr2_+_91256144 13.878 ENSMUST00000154959.1
ENSMUST00000059566.4
 Pacsin3

protein kinase C and casein kinase substrate in neurons 3

chr17_-_34000257 13.655 ENSMUST00000087189.6
ENSMUST00000173075.1
ENSMUST00000172760.1
ENSMUST00000172912.1
ENSMUST00000025181.10
 H2-K1




histocompatibility 2, K1, K region




chr2_+_119618717 13.631 ENSMUST00000028771.7
 Nusap1
nucleolar and spindle associated protein 1
chr18_+_34625009 13.428 ENSMUST00000166044.1
 Kif20a
kinesin family member 20A
chr7_-_142899985 13.207 ENSMUST00000000219.3
 Th
tyrosine hydroxylase

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 135 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.3 71.9 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
9.2 46.2 GO:0015671 oxygen transport(GO:0015671)
0.5 35.3 GO:0006334 nucleosome assembly(GO:0006334)
2.4 31.2 GO:0042573 retinoic acid metabolic process(GO:0042573) positive regulation of collateral sprouting(GO:0048672)
1.5 29.6 GO:0019430 removal of superoxide radicals(GO:0019430)
8.9 26.8 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
8.9 26.6 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
1.3 25.7 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
1.3 24.2 GO:0000920 cell separation after cytokinesis(GO:0000920)
4.5 22.3 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
1.0 20.5 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.2 16.4 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
3.2 16.0 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
3.9 15.7 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
2.6 15.4 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
2.2 15.3 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
1.1 15.2 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.2 14.6 GO:0002088 lens development in camera-type eye(GO:0002088)
2.8 14.1 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.8 14.0 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 79 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.5 112.8 GO:0000786 nucleosome(GO:0000786)
0.0 47.6 GO:0005654 nucleoplasm(GO:0005654)
0.1 40.5 GO:0005667 transcription factor complex(GO:0005667)
3.7 29.5 GO:0005833 hemoglobin complex(GO:0005833)
1.1 28.9 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.6 27.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.2 25.9 GO:0000793 condensed chromosome(GO:0000793)
0.4 24.2 GO:0005871 kinesin complex(GO:0005871)
0.1 24.1 GO:0005802 trans-Golgi network(GO:0005802)
0.1 22.0 GO:0031012 extracellular matrix(GO:0031012)
2.3 16.4 GO:0097452 GAIT complex(GO:0097452)
0.2 16.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
4.0 16.0 GO:0045098 type III intermediate filament(GO:0045098)
1.1 13.7 GO:0042612 MHC class I protein complex(GO:0042612)
0.3 13.6 GO:0005876 spindle microtubule(GO:0005876)
0.5 13.2 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 13.2 GO:0043209 myelin sheath(GO:0043209)
0.0 11.4 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
2.3 11.3 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.5 11.1 GO:0010369 chromocenter(GO:0010369)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 97 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 84.2 GO:0042393 histone binding(GO:0042393)
9.2 46.2 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 33.4 GO:0003677 DNA binding(GO:0003677)
0.9 31.3 GO:0071837 HMG box domain binding(GO:0071837)
5.2 31.2 GO:0019841 retinol binding(GO:0019841)
0.1 27.3 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
2.2 26.5 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
1.7 25.7 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 25.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.4 24.2 GO:0003777 microtubule motor activity(GO:0003777)
1.1 23.3 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.5 22.3 GO:0005507 copper ion binding(GO:0005507)
0.5 19.7 GO:0005504 fatty acid binding(GO:0005504)
2.1 16.7 GO:0005212 structural constituent of eye lens(GO:0005212)
5.5 16.4 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
4.0 16.0 GO:1990254 keratin filament binding(GO:1990254)
2.6 15.7 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.7 14.1 GO:0070628 proteasome binding(GO:0070628)
1.0 13.7 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.1 13.6 GO:0008017 microtubule binding(GO:0008017)