Motif ID: Tbx1_Eomes

Z-value: 0.792

Transcription factors associated with Tbx1_Eomes:

Gene SymbolEntrez IDGene Name
Eomes ENSMUSG00000032446.8 Eomes
Tbx1 ENSMUSG00000009097.9 Tbx1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Eomesmm10_v2_chr9_+_118478344_1184784510.508.8e-06Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Tbx1_Eomes

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_+_26229707 11.955 ENSMUST00000060716.5
ENSMUST00000164660.1
Samd3

sterile alpha motif domain containing 3

chr1_+_6730051 11.691 ENSMUST00000043578.6
ENSMUST00000131467.1
ENSMUST00000150761.1
ENSMUST00000151281.1
St18



suppression of tumorigenicity 18



chr4_+_125490688 9.766 ENSMUST00000030676.7
Grik3
glutamate receptor, ionotropic, kainate 3
chr2_-_13011747 9.319 ENSMUST00000061545.5
C1ql3
C1q-like 3
chr1_-_138847579 8.418 ENSMUST00000093486.3
ENSMUST00000046870.6
Lhx9

LIM homeobox protein 9

chr9_-_43239816 7.611 ENSMUST00000034512.5
Oaf
OAF homolog (Drosophila)
chr6_-_94700137 7.212 ENSMUST00000101126.2
ENSMUST00000032105.4
Lrig1

leucine-rich repeats and immunoglobulin-like domains 1

chr7_-_28302238 6.948 ENSMUST00000108315.3
Dll3
delta-like 3 (Drosophila)
chr1_+_6730135 6.825 ENSMUST00000155921.1
St18
suppression of tumorigenicity 18
chrX_+_100729917 6.005 ENSMUST00000019503.7
Gdpd2
glycerophosphodiester phosphodiesterase domain containing 2
chr6_+_15196949 5.327 ENSMUST00000151301.1
ENSMUST00000131414.1
ENSMUST00000140557.1
ENSMUST00000115469.1
Foxp2



forkhead box P2



chrX_+_100730178 5.228 ENSMUST00000113744.1
Gdpd2
glycerophosphodiester phosphodiesterase domain containing 2
chr17_+_29093763 4.903 ENSMUST00000023829.6
Cdkn1a
cyclin-dependent kinase inhibitor 1A (P21)
chr7_-_100658394 4.650 ENSMUST00000138830.1
ENSMUST00000107044.3
ENSMUST00000116287.2
Plekhb1


pleckstrin homology domain containing, family B (evectins) member 1


chr14_+_62292475 3.954 ENSMUST00000166879.1
Rnaseh2b
ribonuclease H2, subunit B
chr12_+_3891728 3.703 ENSMUST00000172689.1
ENSMUST00000111186.1
Dnmt3a

DNA methyltransferase 3A

chr18_-_46212595 3.558 ENSMUST00000037011.4
Trim36
tripartite motif-containing 36
chr9_-_95845215 3.509 ENSMUST00000093800.2
Pls1
plastin 1 (I-isoform)
chr1_+_153665274 3.403 ENSMUST00000152114.1
ENSMUST00000111812.1
Rgs8

regulator of G-protein signaling 8

chr6_-_24956106 3.339 ENSMUST00000127247.2
Tmem229a
transmembrane protein 229A
chr7_-_100658364 3.320 ENSMUST00000107043.1
Plekhb1
pleckstrin homology domain containing, family B (evectins) member 1
chr2_+_164562579 3.162 ENSMUST00000017867.3
ENSMUST00000109344.2
ENSMUST00000109345.2
Wfdc2


WAP four-disulfide core domain 2


chr11_-_84068357 3.147 ENSMUST00000100705.4
Dusp14
dual specificity phosphatase 14
chr1_+_132316112 3.055 ENSMUST00000082125.5
ENSMUST00000072177.7
Nuak2

NUAK family, SNF1-like kinase, 2

chr10_-_92162753 3.039 ENSMUST00000182197.1
Rmst
rhabdomyosarcoma 2 associated transcript (non-coding RNA)
chr14_-_51988829 2.983 ENSMUST00000181008.1
Gm16617
predicted gene, 16617
chr10_+_4710119 2.973 ENSMUST00000105588.1
ENSMUST00000105589.1
Esr1

estrogen receptor 1 (alpha)

chr7_-_115824699 2.894 ENSMUST00000169129.1
Sox6
SRY-box containing gene 6
chr6_+_7555053 2.786 ENSMUST00000090679.2
ENSMUST00000184986.1
Tac1

tachykinin 1

chr1_+_153665666 2.734 ENSMUST00000111814.1
ENSMUST00000111810.1
Rgs8

regulator of G-protein signaling 8

chr5_+_115908644 2.720 ENSMUST00000141101.1
Cit
citron
chr11_-_84068766 2.656 ENSMUST00000018792.5
Dusp14
dual specificity phosphatase 14
chr2_-_57114970 2.601 ENSMUST00000028166.2
Nr4a2
nuclear receptor subfamily 4, group A, member 2
chr17_-_70849644 2.561 ENSMUST00000134654.1
ENSMUST00000172229.1
ENSMUST00000127719.1
Tgif1


TGFB-induced factor homeobox 1


chr2_+_20519776 2.454 ENSMUST00000114604.2
ENSMUST00000066509.3
Etl4

enhancer trap locus 4

chr4_-_109665249 2.444 ENSMUST00000063531.4
Cdkn2c
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr7_-_141443989 2.430 ENSMUST00000026580.5
Lrdd
leucine-rich and death domain containing
chr10_-_120899067 2.420 ENSMUST00000092143.5
Msrb3
methionine sulfoxide reductase B3
chrX_+_101383726 2.347 ENSMUST00000119190.1
Gjb1
gap junction protein, beta 1
chr2_+_71528657 2.331 ENSMUST00000126400.1
Dlx1
distal-less homeobox 1
chr10_+_56377300 2.323 ENSMUST00000068581.7
Gja1
gap junction protein, alpha 1
chrX_+_142681398 2.291 ENSMUST00000112889.1
ENSMUST00000101198.2
ENSMUST00000112891.1
ENSMUST00000087333.2
Tmem164



transmembrane protein 164



chr9_+_35421541 2.241 ENSMUST00000119129.2
Cdon
cell adhesion molecule-related/down-regulated by oncogenes
chr6_-_21851914 2.201 ENSMUST00000134635.1
ENSMUST00000123116.1
ENSMUST00000120965.1
Tspan12


tetraspanin 12


chr1_+_153665587 2.098 ENSMUST00000147700.1
Rgs8
regulator of G-protein signaling 8
chr4_-_132510493 2.087 ENSMUST00000030724.8
Sesn2
sestrin 2
chr13_-_89742490 2.084 ENSMUST00000109546.2
Vcan
versican
chr1_+_153665627 2.073 ENSMUST00000147482.1
Rgs8
regulator of G-protein signaling 8
chrX_-_53269020 2.011 ENSMUST00000114838.1
Fam122b
family with sequence similarity 122, member B
chr1_-_69108039 1.994 ENSMUST00000121473.1
Erbb4
v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
chr8_+_45885479 1.851 ENSMUST00000034053.5
Pdlim3
PDZ and LIM domain 3
chr4_+_117849193 1.793 ENSMUST00000132043.2
ENSMUST00000169990.1
Slc6a9

solute carrier family 6 (neurotransmitter transporter, glycine), member 9

chr4_+_117849361 1.665 ENSMUST00000163288.1
Slc6a9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr11_+_78178105 1.623 ENSMUST00000147819.1
Tlcd1
TLC domain containing 1
chrX_+_153006461 1.443 ENSMUST00000095755.3
Usp51
ubiquitin specific protease 51
chr4_-_42168603 1.440 ENSMUST00000098121.3
Gm13305
predicted gene 13305
chr11_-_117969176 1.363 ENSMUST00000054002.3
Socs3
suppressor of cytokine signaling 3
chr4_-_123750236 1.335 ENSMUST00000102636.3
Akirin1
akirin 1
chr12_-_31634592 1.291 ENSMUST00000020979.7
ENSMUST00000177962.1
Bcap29

B cell receptor associated protein 29

chr4_+_41760454 1.197 ENSMUST00000108040.1
Il11ra1
interleukin 11 receptor, alpha chain 1
chr16_-_50330987 1.165 ENSMUST00000114488.1
Bbx
bobby sox homolog (Drosophila)
chr4_+_84884276 1.149 ENSMUST00000047023.6
Cntln
centlein, centrosomal protein
chr2_+_54436317 1.143 ENSMUST00000112636.1
ENSMUST00000112635.1
ENSMUST00000112634.1
Galnt13


UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13


chr5_+_120513102 1.136 ENSMUST00000111889.1
Slc8b1
solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
chr12_+_88953399 1.101 ENSMUST00000057634.7
Nrxn3
neurexin III
chr18_+_60963517 1.087 ENSMUST00000115295.2
ENSMUST00000039904.6
Camk2a

calcium/calmodulin-dependent protein kinase II alpha

chr19_+_20601958 1.082 ENSMUST00000087638.3
Aldh1a1
aldehyde dehydrogenase family 1, subfamily A1
chr15_-_98831498 1.059 ENSMUST00000168846.1
Prkag1
protein kinase, AMP-activated, gamma 1 non-catalytic subunit
chr11_-_94507337 1.053 ENSMUST00000040692.8
Mycbpap
MYCBP associated protein
chr9_-_69760924 1.046 ENSMUST00000071281.4
Foxb1
forkhead box B1
chrX_-_162829379 1.010 ENSMUST00000041370.4
ENSMUST00000112316.2
ENSMUST00000112315.1
Txlng


taxilin gamma


chr4_+_84884418 1.001 ENSMUST00000169371.2
Cntln
centlein, centrosomal protein
chr3_-_154328634 0.880 ENSMUST00000167744.1
Lhx8
LIM homeobox protein 8
chr4_+_11191354 0.846 ENSMUST00000170901.1
Ccne2
cyclin E2
chrX_+_42150672 0.844 ENSMUST00000069619.7
Stag2
stromal antigen 2
chr3_+_102734496 0.828 ENSMUST00000029451.5
Tspan2
tetraspanin 2
chrX_+_42151002 0.807 ENSMUST00000123245.1
Stag2
stromal antigen 2
chr15_+_74516196 0.761 ENSMUST00000042035.9
Bai1
brain-specific angiogenesis inhibitor 1
chr8_+_106870827 0.749 ENSMUST00000176144.1
ENSMUST00000175987.1
Has3

hyaluronan synthase 3

chr9_-_13818665 0.747 ENSMUST00000150893.1
ENSMUST00000124883.1
Cep57

centrosomal protein 57

chr4_-_35845204 0.731 ENSMUST00000164772.1
ENSMUST00000065173.2
Lingo2

leucine rich repeat and Ig domain containing 2

chrX_-_152016269 0.702 ENSMUST00000026288.4
Ribc1
RIB43A domain with coiled-coils 1
chr11_+_53519725 0.691 ENSMUST00000108987.1
ENSMUST00000121334.1
ENSMUST00000117061.1
Sept8


septin 8


chr6_+_50110837 0.659 ENSMUST00000167628.1
Mpp6
membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
chr9_+_37208291 0.659 ENSMUST00000034632.8
Tmem218
transmembrane protein 218
chr8_-_31918203 0.642 ENSMUST00000073884.4
Nrg1
neuregulin 1
chr3_-_75556759 0.628 ENSMUST00000162138.1
ENSMUST00000029424.5
ENSMUST00000161137.1
Pdcd10


programmed cell death 10


chr7_-_132813528 0.619 ENSMUST00000097999.2
Fam53b
family with sequence similarity 53, member B
chr1_+_164115264 0.578 ENSMUST00000162746.1
Selp
selectin, platelet
chr16_-_56024628 0.562 ENSMUST00000119981.1
ENSMUST00000096021.3
Pcnp

PEST proteolytic signal containing nuclear protein

chrX_+_56454871 0.517 ENSMUST00000039374.2
ENSMUST00000101553.2
Ddx26b

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B

chr10_+_80930071 0.517 ENSMUST00000015456.8
Gadd45b
growth arrest and DNA-damage-inducible 45 beta
chr3_+_51415986 0.507 ENSMUST00000029303.7
Naa15
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr3_+_96629919 0.504 ENSMUST00000048915.6
Rbm8a
RNA binding motif protein 8a
chr7_-_30563184 0.479 ENSMUST00000043898.6
Psenen
presenilin enhancer 2 homolog (C. elegans)
chr19_-_19001099 0.468 ENSMUST00000040153.8
ENSMUST00000112828.1
Rorb

RAR-related orphan receptor beta

chr2_+_27079371 0.442 ENSMUST00000091233.6
Adamtsl2
ADAMTS-like 2
chrX_+_140956892 0.438 ENSMUST00000112971.1
Atg4a
autophagy related 4A, cysteine peptidase
chr2_-_25272380 0.426 ENSMUST00000028342.6
Ssna1
Sjogren's syndrome nuclear autoantigen 1
chr19_+_55894508 0.423 ENSMUST00000142291.1
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr7_-_132813799 0.422 ENSMUST00000097998.2
Fam53b
family with sequence similarity 53, member B
chr3_+_40950631 0.417 ENSMUST00000048490.6
Larp1b
La ribonucleoprotein domain family, member 1B
chr4_-_134018829 0.399 ENSMUST00000051674.2
Lin28a
lin-28 homolog A (C. elegans)
chr1_+_74236479 0.374 ENSMUST00000113820.2
ENSMUST00000006467.7
ENSMUST00000113819.1
Arpc2


actin related protein 2/3 complex, subunit 2


chr10_-_86705485 0.362 ENSMUST00000020238.7
Hsp90b1
heat shock protein 90, beta (Grp94), member 1
chr11_-_109473220 0.357 ENSMUST00000070872.6
Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr4_-_34882919 0.338 ENSMUST00000098163.2
ENSMUST00000047950.5
Zfp292

zinc finger protein 292

chr10_-_128211788 0.333 ENSMUST00000061995.8
Spryd4
SPRY domain containing 4
chr10_-_85916902 0.302 ENSMUST00000037646.7
Prdm4
PR domain containing 4
chr19_+_6057925 0.267 ENSMUST00000179142.1
Fau
Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived)
chr6_-_28261907 0.266 ENSMUST00000115320.1
ENSMUST00000123098.1
ENSMUST00000115321.2
ENSMUST00000155494.1
Zfp800



zinc finger protein 800



chr4_-_49845549 0.253 ENSMUST00000093859.4
ENSMUST00000076674.3
Grin3a

glutamate receptor ionotropic, NMDA3A

chr1_-_161876656 0.253 ENSMUST00000048377.5
Suco
SUN domain containing ossification factor
chr12_+_78861693 0.250 ENSMUST00000071230.7
Eif2s1
eukaryotic translation initiation factor 2, subunit 1 alpha
chr16_-_84835484 0.249 ENSMUST00000114191.1
Atp5j
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F
chr4_-_117156144 0.234 ENSMUST00000102696.4
Rps8
ribosomal protein S8
chr13_+_93304066 0.226 ENSMUST00000109493.1
Homer1
homer homolog 1 (Drosophila)
chr19_+_6057888 0.223 ENSMUST00000043074.5
ENSMUST00000178310.1
Fau

Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived)

chrM_+_9452 0.221 ENSMUST00000082411.1
mt-Nd3
mitochondrially encoded NADH dehydrogenase 3
chr13_-_96542479 0.216 ENSMUST00000022172.4
Polk
polymerase (DNA directed), kappa
chr12_-_56345862 0.210 ENSMUST00000021416.7
Mbip
MAP3K12 binding inhibitory protein 1
chr1_+_66468364 0.178 ENSMUST00000061620.9
Unc80
unc-80 homolog (C. elegans)
chr3_-_103791537 0.170 ENSMUST00000118317.1
Hipk1
homeodomain interacting protein kinase 1
chr19_+_4097392 0.156 ENSMUST00000174514.1
ENSMUST00000174149.1
Cdk2ap2

CDK2-associated protein 2

chr19_-_6057736 0.152 ENSMUST00000007482.6
Mrpl49
mitochondrial ribosomal protein L49
chr1_+_131970589 0.139 ENSMUST00000027695.6
Slc45a3
solute carrier family 45, member 3
chr17_+_35135695 0.138 ENSMUST00000174478.1
ENSMUST00000174281.2
ENSMUST00000173550.1
Bag6


BCL2-associated athanogene 6


chrM_+_8600 0.137 ENSMUST00000082409.1
mt-Co3
mitochondrially encoded cytochrome c oxidase III
chrM_+_7759 0.135 ENSMUST00000082407.1
ENSMUST00000082408.1
mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr19_+_21272276 0.134 ENSMUST00000025659.4
Zfand5
zinc finger, AN1-type domain 5
chr16_-_16527364 0.110 ENSMUST00000069284.7
Fgd4
FYVE, RhoGEF and PH domain containing 4
chr7_-_46795881 0.108 ENSMUST00000107653.1
ENSMUST00000107654.1
ENSMUST00000014562.7
ENSMUST00000152759.1
Hps5



Hermansky-Pudlak syndrome 5 homolog (human)



chr5_-_137786651 0.095 ENSMUST00000031740.9
Mepce
methylphosphate capping enzyme
chr5_-_137786681 0.085 ENSMUST00000132726.1
Mepce
methylphosphate capping enzyme
chrX_+_163909132 0.084 ENSMUST00000033734.7
ENSMUST00000112294.2
Ap1s2

adaptor-related protein complex 1, sigma 2 subunit

chr9_+_120929216 0.069 ENSMUST00000130466.1
Ctnnb1
catenin (cadherin associated protein), beta 1
chr2_-_148045891 0.064 ENSMUST00000109964.1
Foxa2
forkhead box A2
chr6_+_61180313 0.061 ENSMUST00000126214.1
Ccser1
coiled-coil serine rich 1
chr9_+_35211155 0.053 ENSMUST00000034541.5
Srpr
signal recognition particle receptor ('docking protein')
chr2_+_138278481 0.025 ENSMUST00000075410.4
Btbd3
BTB (POZ) domain containing 3
chr1_-_24612700 0.021 ENSMUST00000088336.1
Gm10222
predicted gene 10222
chrM_+_9870 0.020 ENSMUST00000084013.1
mt-Nd4l
mitochondrially encoded NADH dehydrogenase 4L
chr9_-_21073494 0.008 ENSMUST00000010348.5
Fdx1l
ferredoxin 1-like
chr7_-_46795661 0.005 ENSMUST00000123725.1
Hps5
Hermansky-Pudlak syndrome 5 homolog (human)
chr14_+_31251454 0.003 ENSMUST00000022458.4
Bap1
Brca1 associated protein 1

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 7.2 GO:0032474 otolith morphogenesis(GO:0032474)
1.7 8.4 GO:0035262 gonad morphogenesis(GO:0035262)
1.4 6.9 GO:0007386 compartment pattern specification(GO:0007386)
1.2 3.5 GO:0001951 intestinal D-glucose absorption(GO:0001951) terminal web assembly(GO:1902896)
1.2 3.5 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
1.1 11.2 GO:0090527 actin filament reorganization(GO:0090527)
0.9 2.8 GO:2000852 regulation of corticosterone secretion(GO:2000852)
0.9 9.8 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.9 2.6 GO:0051866 general adaptation syndrome(GO:0051866)
0.9 10.3 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.8 2.3 GO:0021893 cerebral cortex GABAergic interneuron fate commitment(GO:0021893)
0.8 2.3 GO:0003104 positive regulation of glomerular filtration(GO:0003104) cell communication by chemical coupling(GO:0010643)
0.7 3.0 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745)
0.7 2.1 GO:0090526 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.5 4.9 GO:0071493 cellular response to UV-B(GO:0071493) replicative senescence(GO:0090399)
0.5 2.4 GO:0030091 protein repair(GO:0030091)
0.5 3.7 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.5 1.4 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.4 5.3 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.4 1.3 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.4 2.0 GO:0007262 STAT protein import into nucleus(GO:0007262)
0.4 0.7 GO:0036118 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.3 2.2 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.3 0.8 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.3 1.1 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.3 2.9 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.3 1.0 GO:0007412 axon target recognition(GO:0007412)
0.2 4.0 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.2 5.0 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.2 2.6 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.2 0.6 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.2 2.7 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.1 3.6 GO:0007340 acrosome reaction(GO:0007340)
0.1 1.7 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 0.6 GO:0007171 cardiac conduction system development(GO:0003161) activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1 0.6 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.1 0.4 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.1 3.1 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 0.9 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.1 0.4 GO:0051697 protein delipidation(GO:0051697)
0.1 0.5 GO:0046549 retinal cone cell development(GO:0046549)
0.1 2.2 GO:0010842 retina layer formation(GO:0010842)
0.1 0.5 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 1.1 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.1 10.7 GO:0050807 regulation of synapse organization(GO:0050807)
0.1 1.1 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.1 0.4 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1 0.5 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.3 GO:1905098 negative regulation of translation in response to stress(GO:0032055) negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0 0.4 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.1 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0 0.5 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.3 GO:0060134 prepulse inhibition(GO:0060134)
0.0 2.1 GO:0008347 glial cell migration(GO:0008347)
0.0 0.5 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.4 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.7 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.2 GO:0040031 snRNA modification(GO:0040031)
0.0 0.4 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.0 0.2 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0 0.8 GO:0006270 DNA replication initiation(GO:0006270)
0.0 1.1 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 0.4 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.0 0.2 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.9 GO:0021884 forebrain neuron development(GO:0021884)
0.0 2.4 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.4 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.1 GO:0036506 maintenance of unfolded protein(GO:0036506) protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.0 1.0 GO:0030500 regulation of bone mineralization(GO:0030500)
0.0 0.1 GO:0030035 microspike assembly(GO:0030035)
0.0 0.2 GO:0046697 decidualization(GO:0046697)
0.0 0.4 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.3 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 0.5 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 1.9 GO:0010466 negative regulation of peptidase activity(GO:0010466)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.9 GO:0070557 PCNA-p21 complex(GO:0070557)
0.7 3.5 GO:1990357 terminal web(GO:1990357)
0.7 4.0 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.3 4.7 GO:0005922 connexon complex(GO:0005922)
0.3 10.9 GO:0032839 dendrite cytoplasm(GO:0032839)
0.3 10.3 GO:0032809 neuronal cell body membrane(GO:0032809)
0.2 3.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.2 3.7 GO:0001741 XY body(GO:0001741)
0.2 0.5 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 0.9 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 0.6 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 2.5 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 9.3 GO:0005581 collagen trimer(GO:0005581)
0.1 7.2 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 1.1 GO:0030061 mitochondrial crista(GO:0030061)
0.1 11.2 GO:0005884 actin filament(GO:0005884)
0.1 0.5 GO:0031415 NatA complex(GO:0031415)
0.1 0.3 GO:0097450 astrocyte end-foot(GO:0097450)
0.1 0.2 GO:0070469 respiratory chain(GO:0070469)
0.1 0.5 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 0.4 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 3.6 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 2.7 GO:0031985 Golgi cisterna(GO:0031985)
0.0 1.1 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.6 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.1 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 1.7 GO:0005814 centriole(GO:0005814)
0.0 2.1 GO:0030018 Z disc(GO:0030018)
0.0 0.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.5 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.2 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 9.8 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
1.1 11.2 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
1.0 3.0 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.5 7.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.5 4.0 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.5 2.3 GO:0071253 connexin binding(GO:0071253)
0.5 3.7 GO:0051718 DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.5 2.7 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.4 2.0 GO:0038132 neuregulin binding(GO:0038132)
0.3 2.1 GO:0070728 leucine binding(GO:0070728)
0.3 2.4 GO:0070191 methionine-R-sulfoxide reductase activity(GO:0070191)
0.3 1.2 GO:0004921 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.3 1.1 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.2 0.7 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.2 10.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.2 2.3 GO:0005243 gap junction channel activity(GO:0005243)
0.2 6.9 GO:0005112 Notch binding(GO:0005112)
0.2 1.1 GO:0001758 retinal dehydrogenase activity(GO:0001758) 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.2 0.6 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.2 0.5 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 0.6 GO:0042806 fucose binding(GO:0042806)
0.1 5.0 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 2.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.4 GO:0050436 microfibril binding(GO:0050436)
0.1 1.9 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 2.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 2.6 GO:0008432 JUN kinase binding(GO:0008432)
0.1 1.1 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 1.1 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 3.2 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 1.1 GO:0016208 AMP binding(GO:0016208)
0.0 0.1 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.4 GO:0046790 virion binding(GO:0046790)
0.0 0.5 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.2 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 3.0 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.7 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.4 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 1.1 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 1.1 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 4.0 GO:0051015 actin filament binding(GO:0051015)
0.0 2.7 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 7.1 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.8 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.7 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.4 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.4 GO:0035198 miRNA binding(GO:0035198)
0.0 1.4 GO:0019210 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.0 0.3 GO:0016594 glycine binding(GO:0016594)
0.0 1.7 GO:0030674 protein binding, bridging(GO:0030674)
0.0 2.6 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)