• All motifs sorted by activity significance
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• Mean activities
• All promoters sorted by FOV

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: Tbx21

Z-value: 1.526

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr1_-_56969864	27.564	ENSMUST00000177424.1	Satb2	special AT-rich sequence binding protein 2
chr1_-_56969827	27.214	ENSMUST00000176759.1	Satb2	special AT-rich sequence binding protein 2
chr9_-_112185726	25.798	ENSMUST00000160240.1 ENSMUST00000162065.1	Arpp21	cyclic AMP-regulated phosphoprotein, 21
chr9_-_112185939	20.391	ENSMUST00000070218.5	Arpp21	cyclic AMP-regulated phosphoprotein, 21
chr18_+_37020097	18.545	ENSMUST00000047614.1	Pcdha2	protocadherin alpha 2
chr11_+_24080664	17.503	ENSMUST00000118955.1	Bcl11a	B cell CLL/lymphoma 11A (zinc finger protein)
chr5_+_98180866	16.401	ENSMUST00000112959.1	Prdm8	PR domain containing 8
chr7_+_45785331	16.309	ENSMUST00000120005.1 ENSMUST00000123585.1	Lmtk3	lemur tyrosine kinase 3
chr14_+_64588112	15.236	ENSMUST00000181808.1	A930011O12Rik	RIKEN cDNA A930011O12 gene
chr3_-_89322883	13.429	ENSMUST00000029673.5	Efna3	ephrin A3
chr9_-_106656081	13.344	ENSMUST00000023959.7	Grm2	glutamate receptor, metabotropic 2
chr6_-_60829826	12.597	ENSMUST00000163779.1	Snca	synuclein, alpha
chr15_-_84105662	12.461	ENSMUST00000082365.5	Sult4a1	sulfotransferase family 4A, member 1
chr18_+_67088287	11.646	ENSMUST00000025402.7	Gnal	guanine nucleotide binding protein, alpha stimulating, olfactory type
chr7_-_126704816	11.575	ENSMUST00000032949.7	Coro1a	coronin, actin binding protein 1A
chr8_+_12984246	10.870	ENSMUST00000110873.3 ENSMUST00000173006.1 ENSMUST00000145067.1	Mcf2l	mcf.2 transforming sequence-like
chrX_+_170009659	10.677	ENSMUST00000179760.1	Gm21887	predicted gene, 21887
chr10_-_13868932	10.524	ENSMUST00000019942.5 ENSMUST00000162610.1	Aig1	androgen-induced 1
chr19_+_44989073	10.060	ENSMUST00000026225.8	Sema4g	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr1_+_62703667	9.816	ENSMUST00000114155.1 ENSMUST00000027112.6 ENSMUST00000063594.6 ENSMUST00000114157.2	Nrp2	neuropilin 2
chr2_-_66440753	9.632	ENSMUST00000112371.2 ENSMUST00000138910.1	Scn1a	sodium channel, voltage-gated, type I, alpha
chr1_+_59912972	9.263	ENSMUST00000036540.5	Fam117b	family with sequence similarity 117, member B
chr5_-_138619751	9.122	ENSMUST00000085852.4 ENSMUST00000110905.2	Zfp68	zinc finger protein 68
chr5_-_39644597	9.003	ENSMUST00000152057.1	Hs3st1	heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr10_-_13868779	8.972	ENSMUST00000105534.3	Aig1	androgen-induced 1
chr1_+_62703285	8.912	ENSMUST00000102822.2 ENSMUST00000075144.5	Nrp2	neuropilin 2
chr13_-_100108337	8.668	ENSMUST00000180822.1	BC001981	cDNA sequence BC001981
chr18_+_37742088	8.296	ENSMUST00000003599.6	Pcdhga9	protocadherin gamma subfamily A, 9
chr10_-_75560330	8.268	ENSMUST00000051129.9	Fam211b	family with sequence similarity 211, member B
chr3_-_127499095	8.258	ENSMUST00000182594.1	Ank2	ankyrin 2, brain
chr5_-_39644634	8.250	ENSMUST00000053116.6	Hs3st1	heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr5_-_138619702	8.164	ENSMUST00000063262.4	Zfp68	zinc finger protein 68
chr6_-_50261743	8.053	ENSMUST00000101405.3 ENSMUST00000165099.1 ENSMUST00000170142.1	Dfna5	deafness, autosomal dominant 5 (human)
chr7_-_4789541	7.642	ENSMUST00000168578.1	Tmem238	transmembrane protein 238
chr2_+_28641227	7.572	ENSMUST00000028155.5 ENSMUST00000113869.1 ENSMUST00000113867.2	Tsc1	tuberous sclerosis 1
chr6_-_50261943	7.440	ENSMUST00000167893.1	Dfna5	deafness, autosomal dominant 5 (human)
chrX_+_74297097	7.432	ENSMUST00000019231.5 ENSMUST00000147900.1 ENSMUST00000147275.1 ENSMUST00000114171.3	Atp6ap1	ATPase, H+ transporting, lysosomal accessory protein 1
chr6_-_38124568	7.345	ENSMUST00000040259.4	Atp6v0a4	ATPase, H+ transporting, lysosomal V0 subunit A4
chr1_+_34801704	6.794	ENSMUST00000047664.9	Arhgef4	Rho guanine nucleotide exchange factor (GEF) 4
chr6_-_142964404	6.722	ENSMUST00000032421.3	St8sia1	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr5_-_138619653	6.718	ENSMUST00000129832.1	Zfp68	zinc finger protein 68
chrX_-_136868537	6.297	ENSMUST00000058814.6	Rab9b	RAB9B, member RAS oncogene family
chr8_+_25849618	6.289	ENSMUST00000098858.3	Kcnu1	potassium channel, subfamily U, member 1
chr1_+_179546303	6.108	ENSMUST00000040706.8	Cnst	consortin, connexin sorting protein
chr17_-_56074542	6.002	ENSMUST00000139371.1	Ubxn6	UBX domain protein 6
chr8_-_105701077	5.900	ENSMUST00000042608.6	Acd	adrenocortical dysplasia
chr11_-_118248590	5.781	ENSMUST00000106305.2	Cyth1	cytohesin 1
chr5_-_36582381	5.749	ENSMUST00000141043.1 ENSMUST00000031094.8	Tbc1d14	TBC1 domain family, member 14
chr11_+_103171081	5.571	ENSMUST00000042286.5	Fmnl1	formin-like 1
chr9_-_35558522	5.454	ENSMUST00000034612.5	Ddx25	DEAD (Asp-Glu-Ala-Asp) box polypeptide 25
chr10_+_7792891	5.425	ENSMUST00000015901.4	Ppil4	peptidylprolyl isomerase (cyclophilin)-like 4
chr12_-_87233556	5.239	ENSMUST00000021423.7	Noxred1	NADP+ dependent oxidoreductase domain containing 1
chr2_-_167043494	5.206	ENSMUST00000067584.6	Znfx1	zinc finger, NFX1-type containing 1
chr17_-_33713372	5.160	ENSMUST00000173392.1	March2	membrane-associated ring finger (C3HC4) 2
chr11_-_65162904	5.080	ENSMUST00000093002.5 ENSMUST00000047463.8	Arhgap44	Rho GTPase activating protein 44
chr11_+_88047302	5.028	ENSMUST00000139129.2	Srsf1	serine/arginine-rich splicing factor 1
chr6_-_101377897	4.918	ENSMUST00000075994.6	Pdzrn3	PDZ domain containing RING finger 3
chr11_-_120643643	4.879	ENSMUST00000141254.1 ENSMUST00000170556.1 ENSMUST00000151876.1 ENSMUST00000026133.8 ENSMUST00000139706.1	Pycr1	pyrroline-5-carboxylate reductase 1
chr7_-_29954049	4.491	ENSMUST00000108211.1 ENSMUST00000108205.1	Zfp74	zinc finger protein 74
chr11_+_22971991	4.376	ENSMUST00000049506.5	Zrsr1	zinc finger (CCCH type), RNA binding motif and serine/arginine rich 1
chr1_+_60409612	4.168	ENSMUST00000052332.8	Abi2	abl-interactor 2
chr7_-_27178835	4.152	ENSMUST00000093040.6	Rab4b	RAB4B, member RAS oncogene family
chr19_-_6128208	4.148	ENSMUST00000025702.7	Snx15	sorting nexin 15
chr16_-_4003750	4.127	ENSMUST00000171658.1 ENSMUST00000171762.1	Slx4	SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)
chr4_+_109000770	3.959	ENSMUST00000106644.2	Nrd1	nardilysin, N-arginine dibasic convertase, NRD convertase 1
chr13_+_104178797	3.890	ENSMUST00000022225.5 ENSMUST00000069187.5	Trim23	tripartite motif-containing 23
chrX_+_99821021	3.888	ENSMUST00000096363.2	Tmem28	transmembrane protein 28
chr1_-_133131782	3.860	ENSMUST00000180528.1	Gm26616	predicted gene, 26616
chr9_-_85749308	3.800	ENSMUST00000039213.8	Ibtk	inhibitor of Bruton agammaglobulinemia tyrosine kinase
chrX_-_95444789	3.570	ENSMUST00000084535.5	Amer1	APC membrane recruitment 1
chr6_+_83101565	3.561	ENSMUST00000101254.3	Ccdc142	coiled-coil domain containing 142
chr1_-_179546261	3.557	ENSMUST00000027769.5	Tfb2m	transcription factor B2, mitochondrial
chr4_+_74242468	3.482	ENSMUST00000077851.3	Kdm4c	lysine (K)-specific demethylase 4C
chr16_+_75592844	3.446	ENSMUST00000114249.1 ENSMUST00000046378.7 ENSMUST00000114253.1	Rbm11	RNA binding motif protein 11
chr3_-_94436574	3.372	ENSMUST00000029787.4	Oaz3	ornithine decarboxylase antizyme 3
chr4_-_155669171	3.366	ENSMUST00000103176.3	Mib2	mindbomb homolog 2 (Drosophila)
chr7_+_128062657	3.362	ENSMUST00000120355.1 ENSMUST00000106240.2 ENSMUST00000098015.3	Itgam	integrin alpha M
chr17_+_6270475	3.208	ENSMUST00000088940.4	Tmem181a	transmembrane protein 181A
chr8_+_105701142	3.060	ENSMUST00000098444.2	Pard6a	par-6 (partitioning defective 6,) homolog alpha (C. elegans)
chr14_+_54426902	3.018	ENSMUST00000010550.7	Mrpl52	mitochondrial ribosomal protein L52
chr2_+_30364227	2.927	ENSMUST00000077977.7 ENSMUST00000140075.2	Fam73b	family with sequence similarity 73, member B
chr2_+_55411790	2.818	ENSMUST00000155997.1 ENSMUST00000128307.1	Gm14033	predicted gene 14033
chr2_+_84678396	2.780	ENSMUST00000102645.3	Med19	mediator of RNA polymerase II transcription, subunit 19 homolog (yeast)
chr16_+_8470763	2.720	ENSMUST00000046470.9 ENSMUST00000150790.1 ENSMUST00000142899.1	Mettl22	methyltransferase like 22
chr1_+_153874335	2.660	ENSMUST00000055314.3	Gm5531	predicted gene 5531
chr12_-_4874341	2.585	ENSMUST00000137337.1 ENSMUST00000045921.7	Mfsd2b	major facilitator superfamily domain containing 2B
chr1_-_152090308	2.505	ENSMUST00000044581.7	1700025G04Rik	RIKEN cDNA 1700025G04 gene
chr16_-_20426322	2.503	ENSMUST00000115547.2 ENSMUST00000096199.4	Abcc5	ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr3_+_106684943	2.380	ENSMUST00000098751.3	Lrif1	ligand dependent nuclear receptor interacting factor 1
chr9_-_86546795	2.316	ENSMUST00000167814.1	Gm17530	predicted gene, 17530
chr13_+_54789500	2.298	ENSMUST00000163915.1 ENSMUST00000099503.3 ENSMUST00000171859.1	Tspan17	tetraspanin 17
chr19_+_12460749	2.261	ENSMUST00000081035.7	Mpeg1	macrophage expressed gene 1
chr19_+_5425121	2.218	ENSMUST00000159759.1	AI837181	expressed sequence AI837181
chr2_+_164823001	2.178	ENSMUST00000132282.1	Zswim1	zinc finger SWIM-type containing 1
chr8_-_84822823	2.165	ENSMUST00000065539.4	Dand5	DAN domain family, member 5
chr13_+_21945084	2.122	ENSMUST00000176511.1 ENSMUST00000102978.1 ENSMUST00000152258.2	Zfp184	zinc finger protein 184 (Kruppel-like)
chr19_+_34192229	2.106	ENSMUST00000054956.8	Stambpl1	STAM binding protein like 1
chr6_-_113377510	2.051	ENSMUST00000099118.2	Tada3	transcriptional adaptor 3
chr11_-_74590186	2.028	ENSMUST00000102521.1	Rap1gap2	RAP1 GTPase activating protein 2
chr3_-_89402650	1.948	ENSMUST00000168325.1 ENSMUST00000057431.5	Lenep	lens epithelial protein
chr17_-_56074932	1.929	ENSMUST00000019722.5	Ubxn6	UBX domain protein 6
chr4_-_117914968	1.838	ENSMUST00000036156.5	Ipo13	importin 13
chr18_+_9958147	1.829	ENSMUST00000025137.7	Thoc1	THO complex 1
chr10_-_62578387	1.628	ENSMUST00000162525.1 ENSMUST00000159704.1 ENSMUST00000162759.1 ENSMUST00000065887.7	2510003E04Rik	RIKEN cDNA 2510003E04 gene
chr12_+_73286779	1.582	ENSMUST00000140523.1	Slc38a6	solute carrier family 38, member 6
chr17_-_24527830	1.460	ENSMUST00000176353.1 ENSMUST00000176237.1	Traf7	TNF receptor-associated factor 7
chr17_-_24527925	1.371	ENSMUST00000176652.1	Traf7	TNF receptor-associated factor 7
chr5_-_24730635	1.322	ENSMUST00000068693.5	Wdr86	WD repeat domain 86
chr9_+_110419750	1.233	ENSMUST00000035061.6	Ngp	neutrophilic granule protein
chr6_-_113377712	1.199	ENSMUST00000113107.1 ENSMUST00000113106.1	Tada3	transcriptional adaptor 3
chr10_-_39899238	1.174	ENSMUST00000178563.1	AA474331	expressed sequence AA474331
chr2_-_37703845	1.134	ENSMUST00000155237.1	Strbp	spermatid perinuclear RNA binding protein
chr5_-_120777628	1.047	ENSMUST00000044833.8	Oas3	2'-5' oligoadenylate synthetase 3
chr16_-_20425881	1.046	ENSMUST00000077867.3	Abcc5	ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr7_-_13034722	0.986	ENSMUST00000005711.4	Chmp2a	charged multivesicular body protein 2A
chr12_-_113260217	0.982	ENSMUST00000178282.1	Igha	immunoglobulin heavy constant alpha
chr9_+_55326913	0.962	ENSMUST00000085754.3 ENSMUST00000034862.4	AI118078	expressed sequence AI118078
chr4_+_115563649	0.960	ENSMUST00000141033.1 ENSMUST00000030486.8 ENSMUST00000126645.1 ENSMUST00000030480.3	Cyp4a31	cytochrome P450, family 4, subfamily a, polypeptide 31
chr13_-_8870999	0.953	ENSMUST00000177404.1 ENSMUST00000176922.1 ENSMUST00000021572.4	Wdr37	WD repeat domain 37
chr3_-_63964659	0.946	ENSMUST00000161659.1	Slc33a1	solute carrier family 33 (acetyl-CoA transporter), member 1
chr19_+_46573362	0.796	ENSMUST00000026011.6	Sfxn2	sideroflexin 2
chr6_+_113378113	0.792	ENSMUST00000171058.1 ENSMUST00000156898.1	Arpc4	actin related protein 2/3 complex, subunit 4
chr6_+_90619241	0.786	ENSMUST00000032177.8	Slc41a3	solute carrier family 41, member 3
chr5_-_113989739	0.701	ENSMUST00000077689.7	Ssh1	slingshot homolog 1 (Drosophila)
chr9_+_108049254	0.662	ENSMUST00000112295.2 ENSMUST00000047947.7	Gmppb	GDP-mannose pyrophosphorylase B
chr7_+_18884679	0.657	ENSMUST00000032573.6	Pglyrp1	peptidoglycan recognition protein 1
chr11_-_118415794	0.641	ENSMUST00000164927.1	Cant1	calcium activated nucleotidase 1
chr17_+_13760502	0.560	ENSMUST00000139347.1 ENSMUST00000156591.1 ENSMUST00000170827.2 ENSMUST00000139666.1 ENSMUST00000137784.1 ENSMUST00000137708.1 ENSMUST00000150848.1	Mllt4	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
chr11_-_74590065	0.554	ENSMUST00000145524.1 ENSMUST00000047488.7	Rap1gap2	RAP1 GTPase activating protein 2
chr12_+_73286868	0.526	ENSMUST00000153941.1 ENSMUST00000122920.1 ENSMUST00000101313.3	Slc38a6	solute carrier family 38, member 6
chr2_+_3118335	0.506	ENSMUST00000115099.2	Fam171a1	family with sequence similarity 171, member A1
chr1_+_183388981	0.502	ENSMUST00000097043.5	Taf1a	TATA box binding protein (Tbp)-associated factor, RNA polymerase I, A
chr3_+_137918526	0.501	ENSMUST00000168345.1	Lamtor3	late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
chr6_-_113377866	0.445	ENSMUST00000032410.7	Tada3	transcriptional adaptor 3
chr4_+_154869585	0.361	ENSMUST00000079269.7 ENSMUST00000163732.1 ENSMUST00000080559.6	Mmel1	membrane metallo-endopeptidase-like 1
chr13_-_100650981	0.326	ENSMUST00000022136.6 ENSMUST00000177848.1	Rad17	RAD17 homolog (S. pombe)
chr11_+_70451905	0.130	ENSMUST00000151013.1 ENSMUST00000019067.7	Med11	mediator of RNA polymerase II transcription, subunit 11 homolog (S. cerevisiae)
chr2_+_3118407	0.026	ENSMUST00000091505.4	Fam171a1	family with sequence similarity 171, member A1
chrX_-_152769461	0.019	ENSMUST00000101141.2 ENSMUST00000062317.4	Shroom2	shroom family member 2
chr7_+_27607997	0.003	ENSMUST00000142365.1	Akt2	thymoma viral proto-oncogene 2

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
6.2	18.7	GO:0021649	vestibulocochlear nerve morphogenesis(GO:0021648) vestibulocochlear nerve structural organization(GO:0021649) ganglion morphogenesis(GO:0061552) dorsal root ganglion morphogenesis(GO:1904835)
3.4	54.8	GO:0021902	commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
3.1	12.6	GO:0010040	response to iron(II) ion(GO:0010040) positive regulation of hydrogen peroxide metabolic process(GO:0010726) negative regulation of synaptic transmission, dopaminergic(GO:0032227) negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963) cellular response to copper ion(GO:0071280) regulation of peroxidase activity(GO:2000468)
2.5	7.6	GO:0043379	memory T cell differentiation(GO:0043379)
2.5	7.4	GO:2001206	positive regulation of osteoclast development(GO:2001206)
2.0	6.1	GO:0042998	positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
2.0	5.9	GO:1904742	regulation of telomeric DNA binding(GO:1904742)
1.9	11.6	GO:0032796	uropod organization(GO:0032796)
1.4	4.1	GO:1904431	positive regulation of t-circle formation(GO:1904431)
1.3	17.5	GO:0048672	positive regulation of collateral sprouting(GO:0048672)
1.3	10.1	GO:0006561	proline biosynthetic process(GO:0006561)
1.3	52.9	GO:0034605	cellular response to heat(GO:0034605)
1.2	7.3	GO:0070070	proton-transporting V-type ATPase complex assembly(GO:0070070)
1.2	16.4	GO:0021540	corpus callosum morphogenesis(GO:0021540)
1.1	3.4	GO:0014005	microglia differentiation(GO:0014004) microglia development(GO:0014005)
1.1	3.2	GO:0009405	pathogenesis(GO:0009405)
1.1	11.6	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
1.0	9.6	GO:0019227	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
1.0	5.7	GO:0071955	recycling endosome to Golgi transport(GO:0071955)
0.9	8.3	GO:0036371	protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.8	3.4	GO:1902268	negative regulation of polyamine transmembrane transport(GO:1902268)
0.6	5.0	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
0.6	5.6	GO:0051014	actin filament severing(GO:0051014)
0.6	1.8	GO:0048296	negative regulation of isotype switching(GO:0045829) isotype switching to IgA isotypes(GO:0048290) regulation of isotype switching to IgA isotypes(GO:0048296)
0.6	3.6	GO:2001012	mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.5	10.9	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.5	4.2	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.4	3.7	GO:0090043	regulation of tubulin deacetylation(GO:0090043)
0.4	3.6	GO:0006390	transcription from mitochondrial promoter(GO:0006390)
0.4	13.3	GO:0014047	glutamate secretion(GO:0014047)
0.4	2.2	GO:1900116	sequestering of extracellular ligand from receptor(GO:0035581) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.3	3.5	GO:0033169	histone H3-K9 demethylation(GO:0033169) regulation of histone H3-K9 trimethylation(GO:1900112) negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.3	1.0	GO:1903722	regulation of centriole elongation(GO:1903722)
0.3	1.2	GO:1901491	negative regulation of lymphangiogenesis(GO:1901491)
0.3	13.4	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.3	3.1	GO:0045217	cell-cell junction maintenance(GO:0045217)
0.3	10.1	GO:0048843	negative regulation of axon extension involved in axon guidance(GO:0048843)
0.2	2.8	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.2	5.8	GO:0032011	ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.2	5.4	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.2	15.5	GO:2001244	inner ear receptor cell differentiation(GO:0060113) positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.2	16.3	GO:0010923	negative regulation of phosphatase activity(GO:0010923)
0.2	4.0	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.2	0.6	GO:0034331	cell junction maintenance(GO:0034331)
0.2	3.9	GO:0006471	protein ADP-ribosylation(GO:0006471)
0.1	1.0	GO:0060700	regulation of ribonuclease activity(GO:0060700)
0.1	1.8	GO:0042921	glucocorticoid receptor signaling pathway(GO:0042921)
0.1	0.7	GO:0098543	detection of bacterium(GO:0016045) negative regulation of natural killer cell activation(GO:0032815) detection of other organism(GO:0098543)
0.1	5.5	GO:0006406	mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.1	7.5	GO:0030032	lamellipodium assembly(GO:0030032)
0.1	6.3	GO:0042147	retrograde transport, endosome to Golgi(GO:0042147)
0.1	2.3	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.1	1.0	GO:0002385	mucosal immune response(GO:0002385)
0.1	3.4	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1	2.1	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.1	12.5	GO:0008202	steroid metabolic process(GO:0008202)
0.0	3.8	GO:0051209	release of sequestered calcium ion into cytosol(GO:0051209) negative regulation of sequestering of calcium ion(GO:0051283)
0.0	0.6	GO:0009191	ribonucleoside diphosphate catabolic process(GO:0009191)
0.0	6.3	GO:0071805	potassium ion transmembrane transport(GO:0071805)
0.0	1.1	GO:0007638	mechanosensory behavior(GO:0007638)
0.0	0.8	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0	2.4	GO:0046323	glucose import(GO:0046323)
0.0	3.4	GO:0007219	Notch signaling pathway(GO:0007219)
0.0	0.5	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.0	2.6	GO:0010977	negative regulation of neuron projection development(GO:0010977)
0.0	0.2	GO:0000470	maturation of LSU-rRNA(GO:0000470)
0.0	0.9	GO:0060395	SMAD protein signal transduction(GO:0060395)
0.0	0.8	GO:0055072	iron ion homeostasis(GO:0055072)
0.0	3.5	GO:0015711	organic anion transport(GO:0015711)
0.0	0.5	GO:0006360	transcription from RNA polymerase I promoter(GO:0006360)
0.0	4.9	GO:0006897	endocytosis(GO:0006897)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.1	12.6	GO:0031092	platelet alpha granule membrane(GO:0031092)
2.5	7.6	GO:0033596	TSC1-TSC2 complex(GO:0033596)
1.4	4.1	GO:0070522	ERCC4-ERCC1 complex(GO:0070522)
1.0	7.3	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.8	5.9	GO:0070187	telosome(GO:0070187)
0.8	7.4	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.7	2.9	GO:0031230	intrinsic component of cell outer membrane(GO:0031230) integral component of cell outer membrane(GO:0045203)
0.7	5.5	GO:0033391	chromatoid body(GO:0033391)
0.6	9.6	GO:0034706	voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.5	4.4	GO:0089701	U2AF(GO:0089701)
0.5	54.8	GO:0000118	histone deacetylase complex(GO:0000118)
0.5	11.6	GO:0001891	phagocytic cup(GO:0001891)
0.3	8.3	GO:0031430	M band(GO:0031430)
0.3	4.2	GO:0031209	SCAR complex(GO:0031209)
0.2	11.6	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.2	11.9	GO:0045335	phagocytic vesicle(GO:0045335)
0.2	1.8	GO:0000347	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.2	3.7	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.2	16.0	GO:0035097	histone methyltransferase complex(GO:0035097)
0.2	13.3	GO:0042734	presynaptic membrane(GO:0042734)
0.2	3.4	GO:0008305	integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.2	5.0	GO:0035145	exon-exon junction complex(GO:0035145)
0.1	2.4	GO:0032593	insulin-responsive compartment(GO:0032593)
0.1	11.1	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1	6.7	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.1	3.5	GO:0005721	pericentric heterochromatin(GO:0005721)
0.1	13.4	GO:0031225	anchored component of membrane(GO:0031225)
0.1	1.0	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
0.1	0.5	GO:0000120	RNA polymerase I transcription factor complex(GO:0000120)
0.1	1.0	GO:0000815	ESCRT III complex(GO:0000815)
0.1	6.3	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
0.1	5.7	GO:0005776	autophagosome(GO:0005776)
0.1	0.5	GO:0071986	Ragulator complex(GO:0071986)
0.1	2.9	GO:0016592	mediator complex(GO:0016592)
0.1	3.6	GO:0042645	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1	20.9	GO:0016604	nuclear body(GO:0016604)
0.1	0.8	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	5.1	GO:0031256	leading edge membrane(GO:0031256)
0.0	3.4	GO:0036126	sperm flagellum(GO:0036126)
0.0	6.1	GO:0030133	transport vesicle(GO:0030133)
0.0	10.4	GO:0030424	axon(GO:0030424)
0.0	0.2	GO:0070545	PeBoW complex(GO:0070545)
0.0	6.2	GO:0000151	ubiquitin ligase complex(GO:0000151)
0.0	4.9	GO:0005764	lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0	0.6	GO:0005913	cell-cell adherens junction(GO:0005913)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.9	11.6	GO:0050827	toxin receptor binding(GO:0050827)
2.9	17.3	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
2.7	18.7	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
2.7	13.3	GO:0001640	adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
2.5	10.1	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
2.1	12.6	GO:0050544	arachidonic acid binding(GO:0050544)
2.1	6.3	GO:0060072	large conductance calcium-activated potassium channel activity(GO:0060072)
2.1	16.4	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
1.2	6.1	GO:0071253	connexin binding(GO:0071253)
1.2	11.6	GO:0032036	myosin heavy chain binding(GO:0032036)
1.1	6.7	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.9	3.8	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.8	3.4	GO:0071532	ornithine decarboxylase inhibitor activity(GO:0008073) ankyrin repeat binding(GO:0071532)
0.8	4.1	GO:0017108	5'-flap endonuclease activity(GO:0017108)
0.7	2.2	GO:0016015	morphogen activity(GO:0016015)
0.7	7.3	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.6	7.4	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.6	10.9	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.5	13.1	GO:0032794	GTPase activating protein binding(GO:0032794)
0.5	5.0	GO:0050733	RS domain binding(GO:0050733)
0.5	9.6	GO:0031402	sodium ion binding(GO:0031402)
0.5	12.5	GO:0034930	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131)
0.4	3.5	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.4	5.9	GO:0070182	DNA polymerase binding(GO:0070182)
0.4	3.2	GO:0015643	toxic substance binding(GO:0015643)
0.3	0.9	GO:0008521	acetyl-CoA transporter activity(GO:0008521)
0.3	6.8	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.3	8.3	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.3	10.1	GO:0030215	semaphorin receptor binding(GO:0030215)
0.3	13.4	GO:0046875	ephrin receptor binding(GO:0046875)
0.2	46.2	GO:0005516	calmodulin binding(GO:0005516)
0.2	2.1	GO:0016920	pyroglutamyl-peptidase activity(GO:0016920)
0.2	1.0	GO:0008392	arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.2	4.2	GO:0070064	proline-rich region binding(GO:0070064)
0.2	10.2	GO:0019003	GDP binding(GO:0019003)
0.2	5.8	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2	0.7	GO:0042834	peptidoglycan binding(GO:0042834)
0.2	3.4	GO:0008266	poly(U) RNA binding(GO:0008266)
0.1	3.1	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.1	3.4	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.1	0.6	GO:0004382	guanosine-diphosphatase activity(GO:0004382)
0.1	17.5	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1	5.4	GO:0003755	peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1	3.7	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.1	0.6	GO:0030274	LIM domain binding(GO:0030274)
0.1	1.0	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.1	0.7	GO:0008905	mannose-phosphate guanylyltransferase activity(GO:0008905)
0.1	2.4	GO:0042974	retinoic acid receptor binding(GO:0042974)
0.1	1.2	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1	1.8	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.1	3.6	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1	5.8	GO:0043851	rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) rRNA (uridine-2'-O-)-methyltransferase activity(GO:0008650) rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383) selenocysteine methyltransferase activity(GO:0016205) rRNA (adenine) methyltransferase activity(GO:0016433) rRNA (cytosine) methyltransferase activity(GO:0016434) rRNA (guanine) methyltransferase activity(GO:0016435) 1-phenanthrol methyltransferase activity(GO:0018707) protein-arginine N5-methyltransferase activity(GO:0019702) dimethylarsinite methyltransferase activity(GO:0034541) 4,5-dihydroxybenzo(a)pyrene methyltransferase activity(GO:0034807) 1-hydroxypyrene methyltransferase activity(GO:0034931) 1-hydroxy-6-methoxypyrene methyltransferase activity(GO:0034933) demethylmenaquinone methyltransferase activity(GO:0043770) cobalt-precorrin-6B C5-methyltransferase activity(GO:0043776) cobalt-precorrin-7 C15-methyltransferase activity(GO:0043777) cobalt-precorrin-5B C1-methyltransferase activity(GO:0043780) cobalt-precorrin-3 C17-methyltransferase activity(GO:0043782) dimethylamine methyltransferase activity(GO:0043791) hydroxyneurosporene-O-methyltransferase activity(GO:0043803) tRNA (adenine-57, 58-N(1)-) methyltransferase activity(GO:0043827) methylamine-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043833) trimethylamine methyltransferase activity(GO:0043834) methanol-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043851) monomethylamine methyltransferase activity(GO:0043852) P-methyltransferase activity(GO:0051994) Se-methyltransferase activity(GO:0051995) 2-phytyl-1,4-naphthoquinone methyltransferase activity(GO:0052624) tRNA (uracil-2'-O-)-methyltransferase activity(GO:0052665) tRNA (cytosine-2'-O-)-methyltransferase activity(GO:0052666) phosphomethylethanolamine N-methyltransferase activity(GO:0052667) tRNA (cytosine-3-)-methyltransferase activity(GO:0052735) rRNA (cytosine-2'-O-)-methyltransferase activity(GO:0070677) rRNA (cytosine-N4-)-methyltransferase activity(GO:0071424) trihydroxyferuloyl spermidine O-methyltransferase activity(GO:0080012)
0.1	40.9	GO:0003682	chromatin binding(GO:0003682)
0.1	20.8	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.1	2.9	GO:0001104	RNA polymerase II transcription cofactor activity(GO:0001104)
0.0	1.0	GO:0070566	adenylyltransferase activity(GO:0070566)
0.0	4.3	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	3.5	GO:0042626	ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0	5.7	GO:0017137	Rab GTPase binding(GO:0017137)
0.0	18.7	GO:0004674	protein serine/threonine kinase activity(GO:0004674)
0.0	0.3	GO:0003689	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	1.5	GO:0008186	ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0	2.1	GO:0015171	amino acid transmembrane transporter activity(GO:0015171)
0.0	1.1	GO:0003727	single-stranded RNA binding(GO:0003727)
0.0	5.6	GO:0043774	UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738)
0.0	4.9	GO:0005543	phospholipid binding(GO:0005543)
0.0	1.0	GO:0003823	antigen binding(GO:0003823)
0.0	0.8	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.0	0.7	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)

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