Motif ID: Tead1

Z-value: 0.730


Transcription factors associated with Tead1:

Gene SymbolEntrez IDGene Name
Tead1 ENSMUSG00000055320.10 Tead1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tead1mm10_v2_chr7_+_112742025_1127420600.405.2e-04Click!


Activity profile for motif Tead1.

activity profile for motif Tead1


Sorted Z-values histogram for motif Tead1

Sorted Z-values for motif Tead1



Network of associatons between targets according to the STRING database.



First level regulatory network of Tead1

PNG image of the network

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Top targets:


Showing 1 to 20 of 102 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_-_54577578 10.088 ENSMUST00000054487.8
 Ajuba
ajuba LIM protein
chr1_+_189728264 9.599 ENSMUST00000097442.2
 Ptpn14
protein tyrosine phosphatase, non-receptor type 14
chr16_+_91225550 9.465 ENSMUST00000035608.8
 Olig2
oligodendrocyte transcription factor 2
chr10_-_87493651 9.415 ENSMUST00000020243.7
 Ascl1
achaete-scute complex homolog 1 (Drosophila)
chr15_+_6386598 9.116 ENSMUST00000080880.5
ENSMUST00000110664.2
ENSMUST00000110663.2
ENSMUST00000161812.1
ENSMUST00000160134.1
 Dab2




disabled 2, mitogen-responsive phosphoprotein




chr11_-_32222233 8.412 ENSMUST00000150381.1
ENSMUST00000144902.1
ENSMUST00000020524.8
 Rhbdf1


rhomboid family 1 (Drosophila)


chr9_-_8004585 8.269 ENSMUST00000086580.5
ENSMUST00000065353.6
 Yap1

yes-associated protein 1

chr10_+_24595623 7.965 ENSMUST00000176228.1
ENSMUST00000129142.1
 Ctgf

connective tissue growth factor

chr2_+_91457501 7.933 ENSMUST00000028689.3
 Lrp4
low density lipoprotein receptor-related protein 4
chr15_+_78842632 7.663 ENSMUST00000059619.1
 Cdc42ep1
CDC42 effector protein (Rho GTPase binding) 1
chr7_-_109616548 7.511 ENSMUST00000077909.1
ENSMUST00000084738.3
 St5

suppression of tumorigenicity 5

chr10_+_24595434 7.465 ENSMUST00000020171.5
 Ctgf
connective tissue growth factor
chr4_-_43558386 7.287 ENSMUST00000130353.1
 Tln1
talin 1
chr19_-_4439388 7.091 ENSMUST00000117462.1
ENSMUST00000048197.3
 Rhod

ras homolog gene family, member D

chr3_-_57575760 6.643 ENSMUST00000029380.7
 Wwtr1
WW domain containing transcription regulator 1
chr8_-_47990535 5.941 ENSMUST00000057561.7
 Wwc2
WW, C2 and coiled-coil domain containing 2
chr2_+_156775409 5.881 ENSMUST00000088552.6
 Myl9
myosin, light polypeptide 9, regulatory
chr11_+_70700473 5.831 ENSMUST00000152618.2
ENSMUST00000102554.1
ENSMUST00000094499.4
ENSMUST00000072187.5
 Kif1c



kinesin family member 1C



chr8_+_57511833 5.559 ENSMUST00000067925.6
 Hmgb2
high mobility group box 2
chr11_-_5381734 5.296 ENSMUST00000172492.1
 Znrf3
zinc and ring finger 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 57 entries
Log-likelihood per target Total log-likelihoodTermDescription
6.3 18.9 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
3.9 15.4 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
2.1 14.9 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
2.6 13.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.3 11.1 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.4 9.6 GO:0001946 lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303)
0.2 9.5 GO:0042058 regulation of epidermal growth factor receptor signaling pathway(GO:0042058)
1.8 9.1 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
2.6 7.9 GO:1904395 regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.6 7.7 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.1 7.5 GO:0070374 positive regulation of ERK1 and ERK2 cascade(GO:0070374)
0.9 7.3 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.2 7.1 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
1.4 6.8 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085)
0.1 6.6 GO:0032611 interleukin-1 beta production(GO:0032611)
0.5 6.3 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.1 5.9 GO:0070527 platelet aggregation(GO:0070527)
0.8 5.6 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
1.4 5.4 GO:0046084 adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
1.1 5.3 GO:0038018 Wnt receptor catabolic process(GO:0038018)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 31 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 48.6 GO:0005667 transcription factor complex(GO:0005667)
0.3 15.4 GO:0005801 cis-Golgi network(GO:0005801)
0.2 10.6 GO:0005871 kinesin complex(GO:0005871)
0.7 9.8 GO:0016460 myosin II complex(GO:0016460)
2.3 9.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 8.4 GO:0001726 ruffle(GO:0001726)
0.5 7.9 GO:0016600 flotillin complex(GO:0016600)
0.0 6.9 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.4 6.8 GO:0002080 acrosomal membrane(GO:0002080)
0.0 6.7 GO:0005925 focal adhesion(GO:0005925)
0.0 5.6 GO:0000793 condensed chromosome(GO:0000793)
0.0 4.9 GO:0005604 basement membrane(GO:0005604)
0.5 4.1 GO:0033269 internode region of axon(GO:0033269)
0.3 2.8 GO:0030478 actin cap(GO:0030478)
0.1 2.4 GO:0035869 ciliary transition zone(GO:0035869)
0.0 2.4 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 2.3 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 2.1 GO:0017053 transcriptional repressor complex(GO:0017053)
0.2 2.0 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.6 1.7 GO:0005896 interleukin-6 receptor complex(GO:0005896)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 49 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 17.5 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.7 15.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.3 11.6 GO:0070888 E-box binding(GO:0070888)
0.2 10.6 GO:0003777 microtubule motor activity(GO:0003777)
0.8 10.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.3 9.5 GO:0071837 HMG box domain binding(GO:0071837)
1.0 9.1 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 8.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.4 8.3 GO:0070064 proline-rich region binding(GO:0070064)
0.3 7.7 GO:0017049 GTP-Rho binding(GO:0017049)
0.2 7.5 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.7 7.3 GO:0030274 LIM domain binding(GO:0030274)
1.4 6.8 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
2.1 6.3 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.6 5.9 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 5.9 GO:0032947 protein complex scaffold(GO:0032947)
0.9 5.6 GO:0050786 RAGE receptor binding(GO:0050786)
0.1 5.4 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 5.1 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.7 4.9 GO:0043237 laminin-1 binding(GO:0043237)