Motif ID: Tead3_Tead4

Z-value: 3.575

Transcription factors associated with Tead3_Tead4:

Gene SymbolEntrez IDGene Name
Tead3 ENSMUSG00000002249.11 Tead3
Tead4 ENSMUSG00000030353.9 Tead4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tead3mm10_v2_chr17_-_28350600_283506810.694.1e-11Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Tead3_Tead4

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_+_24595623 108.918 ENSMUST00000176228.1
ENSMUST00000129142.1
Ctgf

connective tissue growth factor

chr10_+_24595434 104.349 ENSMUST00000020171.5
Ctgf
connective tissue growth factor
chr4_-_43558386 77.693 ENSMUST00000130353.1
Tln1
talin 1
chr14_-_54577578 73.875 ENSMUST00000054487.8
Ajuba
ajuba LIM protein
chr15_+_6386598 72.897 ENSMUST00000080880.5
ENSMUST00000110664.2
ENSMUST00000110663.2
ENSMUST00000161812.1
ENSMUST00000160134.1
Dab2




disabled 2, mitogen-responsive phosphoprotein




chr12_-_80112998 63.274 ENSMUST00000165114.1
ENSMUST00000021552.1
Zfp36l1

zinc finger protein 36, C3H type-like 1

chr11_+_98412461 57.303 ENSMUST00000058295.5
Erbb2
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
chr5_-_137314175 57.157 ENSMUST00000024119.9
Trip6
thyroid hormone receptor interactor 6
chr1_+_189728264 57.054 ENSMUST00000097442.2
Ptpn14
protein tyrosine phosphatase, non-receptor type 14
chr10_-_78591945 49.409 ENSMUST00000040580.6
Syde1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr11_+_112782182 49.131 ENSMUST00000000579.2
Sox9
SRY-box containing gene 9
chr15_+_78842632 45.104 ENSMUST00000059619.1
Cdc42ep1
CDC42 effector protein (Rho GTPase binding) 1
chr3_-_145649970 44.599 ENSMUST00000029846.3
Cyr61
cysteine rich protein 61
chr3_-_57575760 43.117 ENSMUST00000029380.7
Wwtr1
WW domain containing transcription regulator 1
chr7_-_109616548 40.689 ENSMUST00000077909.1
ENSMUST00000084738.3
St5

suppression of tumorigenicity 5

chr18_+_50030977 40.204 ENSMUST00000145726.1
ENSMUST00000128377.1
Tnfaip8

tumor necrosis factor, alpha-induced protein 8

chr9_+_69454066 38.846 ENSMUST00000134907.1
Anxa2
annexin A2
chr13_-_113046357 38.666 ENSMUST00000022282.3
Gpx8
glutathione peroxidase 8 (putative)
chr18_-_78206408 38.523 ENSMUST00000163367.1
Slc14a2
solute carrier family 14 (urea transporter), member 2
chr17_+_78508063 38.400 ENSMUST00000024880.9
Vit
vitrin

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 181 entries
Log-likelihood per target Total log-likelihoodTermDescription
53.3 213.3 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
11.0 88.1 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
17.0 85.1 GO:0035331 negative regulation of hippo signaling(GO:0035331)
14.6 72.9 GO:0032346 positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349) regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
1.4 71.2 GO:0032611 interleukin-1 beta production(GO:0032611)
10.0 70.2 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
5.8 63.3 GO:0060710 chorio-allantoic fusion(GO:0060710)
10.5 63.0 GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
5.2 62.6 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
19.1 57.3 GO:0044849 estrous cycle(GO:0044849)
9.5 57.2 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
2.7 54.4 GO:0001946 lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303)
16.6 49.8 GO:2001139 negative regulation of postsynaptic membrane organization(GO:1901627) negative regulation of dendritic spine maintenance(GO:1902951) negative regulation of phospholipid efflux(GO:1902999) regulation of lipid transport across blood brain barrier(GO:1903000) negative regulation of lipid transport across blood brain barrier(GO:1903001) positive regulation of lipid transport across blood brain barrier(GO:1903002) negative regulation of phospholipid transport(GO:2001139)
6.2 49.4 GO:0016081 synaptic vesicle docking(GO:0016081)
16.4 49.1 GO:0035622 intrahepatic bile duct development(GO:0035622) renal vesicle induction(GO:0072034)
14.9 44.6 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
10.3 41.0 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
3.2 38.9 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.5 38.9 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
1.0 38.7 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 94 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 263.8 GO:0005925 focal adhesion(GO:0005925)
3.9 201.4 GO:0005801 cis-Golgi network(GO:0005801)
0.4 155.6 GO:0005667 transcription factor complex(GO:0005667)
0.1 123.8 GO:0005829 cytosol(GO:0005829)
1.1 80.1 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
18.2 72.9 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
21.0 63.0 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.3 58.1 GO:0016323 basolateral plasma membrane(GO:0016323)
4.4 57.3 GO:0043219 lateral loop(GO:0043219)
0.2 55.7 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
3.8 53.9 GO:0005614 interstitial matrix(GO:0005614)
1.1 52.1 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.3 51.8 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
16.6 49.8 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
2.4 49.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.7 43.1 GO:0005871 kinesin complex(GO:0005871)
12.8 38.5 GO:0005595 collagen type XII trimer(GO:0005595) anchoring collagen complex(GO:0030934)
1.5 36.4 GO:0002102 podosome(GO:0002102)
0.4 35.6 GO:0005604 basement membrane(GO:0005604)
8.7 35.0 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 129 entries
Log-likelihood per target Total log-likelihoodTermDescription
13.4 295.9 GO:0005520 insulin-like growth factor binding(GO:0005520)
1.5 88.1 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
2.1 78.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
7.8 77.7 GO:0030274 LIM domain binding(GO:0030274)
3.4 75.5 GO:0017049 GTP-Rho binding(GO:0017049)
6.2 73.9 GO:0045294 alpha-catenin binding(GO:0045294)
0.5 73.3 GO:0051015 actin filament binding(GO:0051015)
8.1 72.9 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
10.3 72.2 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
1.8 65.3 GO:0017091 AU-rich element binding(GO:0017091)
15.8 63.0 GO:0004859 phospholipase inhibitor activity(GO:0004859) phospholipase A2 inhibitor activity(GO:0019834)
4.4 57.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.4 53.5 GO:0005539 glycosaminoglycan binding(GO:0005539)
16.6 49.8 GO:0046911 hydroxyapatite binding(GO:0046848) metal chelating activity(GO:0046911) phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
4.5 49.1 GO:0097157 pre-mRNA intronic binding(GO:0097157)
5.7 45.4 GO:0018741 alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902)
0.6 43.1 GO:0003777 microtubule motor activity(GO:0003777)
0.2 42.2 GO:0008022 protein C-terminus binding(GO:0008022)
0.2 39.9 GO:0003714 transcription corepressor activity(GO:0003714)
0.2 39.0 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)