Motif ID: Tead3_Tead4

Z-value: 3.575

Transcription factors associated with Tead3_Tead4:

Gene SymbolEntrez IDGene Name
Tead3 ENSMUSG00000002249.11 Tead3
Tead4 ENSMUSG00000030353.9 Tead4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tead3mm10_v2_chr17_-_28350600_283506810.694.1e-11Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Tead3_Tead4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_+_24595623 108.918 ENSMUST00000176228.1
ENSMUST00000129142.1
Ctgf

connective tissue growth factor

chr10_+_24595434 104.349 ENSMUST00000020171.5
Ctgf
connective tissue growth factor
chr4_-_43558386 77.693 ENSMUST00000130353.1
Tln1
talin 1
chr14_-_54577578 73.875 ENSMUST00000054487.8
Ajuba
ajuba LIM protein
chr15_+_6386598 72.897 ENSMUST00000080880.5
ENSMUST00000110664.2
ENSMUST00000110663.2
ENSMUST00000161812.1
ENSMUST00000160134.1
Dab2




disabled 2, mitogen-responsive phosphoprotein




chr12_-_80112998 63.274 ENSMUST00000165114.1
ENSMUST00000021552.1
Zfp36l1

zinc finger protein 36, C3H type-like 1

chr11_+_98412461 57.303 ENSMUST00000058295.5
Erbb2
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
chr5_-_137314175 57.157 ENSMUST00000024119.9
Trip6
thyroid hormone receptor interactor 6
chr1_+_189728264 57.054 ENSMUST00000097442.2
Ptpn14
protein tyrosine phosphatase, non-receptor type 14
chr10_-_78591945 49.409 ENSMUST00000040580.6
Syde1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr11_+_112782182 49.131 ENSMUST00000000579.2
Sox9
SRY-box containing gene 9
chr15_+_78842632 45.104 ENSMUST00000059619.1
Cdc42ep1
CDC42 effector protein (Rho GTPase binding) 1
chr3_-_145649970 44.599 ENSMUST00000029846.3
Cyr61
cysteine rich protein 61
chr3_-_57575760 43.117 ENSMUST00000029380.7
Wwtr1
WW domain containing transcription regulator 1
chr7_-_109616548 40.689 ENSMUST00000077909.1
ENSMUST00000084738.3
St5

suppression of tumorigenicity 5

chr18_+_50030977 40.204 ENSMUST00000145726.1
ENSMUST00000128377.1
Tnfaip8

tumor necrosis factor, alpha-induced protein 8

chr9_+_69454066 38.846 ENSMUST00000134907.1
Anxa2
annexin A2
chr13_-_113046357 38.666 ENSMUST00000022282.3
Gpx8
glutathione peroxidase 8 (putative)
chr18_-_78206408 38.523 ENSMUST00000163367.1
Slc14a2
solute carrier family 14 (urea transporter), member 2
chr17_+_78508063 38.400 ENSMUST00000024880.9
Vit
vitrin
chr8_-_61760067 36.358 ENSMUST00000121493.1
Palld
palladin, cytoskeletal associated protein
chr10_+_93641041 35.608 ENSMUST00000020204.4
Ntn4
netrin 4
chr1_-_72874877 34.953 ENSMUST00000027377.8
Igfbp5
insulin-like growth factor binding protein 5
chr18_+_60911757 32.652 ENSMUST00000040359.5
Arsi
arylsulfatase i
chr7_-_19698206 31.398 ENSMUST00000172808.1
ENSMUST00000174191.1
Apoe

apolipoprotein E

chr18_+_50053282 31.046 ENSMUST00000148159.2
Tnfaip8
tumor necrosis factor, alpha-induced protein 8
chr7_+_128523576 29.044 ENSMUST00000033136.7
Bag3
BCL2-associated athanogene 3
chr11_-_115813621 27.364 ENSMUST00000041684.4
ENSMUST00000156812.1
Caskin2

CASK-interacting protein 2

chr3_-_57575907 27.037 ENSMUST00000120977.1
Wwtr1
WW domain containing transcription regulator 1
chr11_-_32222233 26.906 ENSMUST00000150381.1
ENSMUST00000144902.1
ENSMUST00000020524.8
Rhbdf1


rhomboid family 1 (Drosophila)


chr2_+_91457501 26.697 ENSMUST00000028689.3
Lrp4
low density lipoprotein receptor-related protein 4
chr5_+_63812447 26.125 ENSMUST00000081747.3
0610040J01Rik
RIKEN cDNA 0610040J01 gene
chr14_-_48662740 26.035 ENSMUST00000122009.1
Otx2
orthodenticle homolog 2 (Drosophila)
chr2_+_20519776 25.127 ENSMUST00000114604.2
ENSMUST00000066509.3
Etl4

enhancer trap locus 4

chr18_+_23415400 24.820 ENSMUST00000115832.2
ENSMUST00000047954.7
Dtna

dystrobrevin alpha

chr9_+_69453620 24.195 ENSMUST00000034756.8
ENSMUST00000123470.1
Anxa2

annexin A2

chr11_-_5381734 24.195 ENSMUST00000172492.1
Znrf3
zinc and ring finger 3
chr11_+_70700473 23.708 ENSMUST00000152618.2
ENSMUST00000102554.1
ENSMUST00000094499.4
ENSMUST00000072187.5
Kif1c



kinesin family member 1C



chr10_-_58675631 22.261 ENSMUST00000003312.4
Edar
ectodysplasin-A receptor
chr8_-_47990535 22.077 ENSMUST00000057561.7
Wwc2
WW, C2 and coiled-coil domain containing 2
chr15_-_103366763 21.994 ENSMUST00000023128.6
Itga5
integrin alpha 5 (fibronectin receptor alpha)
chr9_+_44069421 21.758 ENSMUST00000114830.2
Usp2
ubiquitin specific peptidase 2
chr12_-_98737405 21.590 ENSMUST00000170188.1
Ptpn21
protein tyrosine phosphatase, non-receptor type 21
chr4_+_118429701 21.543 ENSMUST00000067896.3
Elovl1
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1
chr7_-_38107490 21.451 ENSMUST00000108023.3
Ccne1
cyclin E1
chr15_-_37458523 21.436 ENSMUST00000116445.2
Ncald
neurocalcin delta
chr2_-_26092149 21.144 ENSMUST00000114159.2
Nacc2
nucleus accumbens associated 2, BEN and BTB (POZ) domain containing
chr8_-_94918012 20.886 ENSMUST00000077955.5
Ccdc102a
coiled-coil domain containing 102A
chrX_+_96456362 20.788 ENSMUST00000079322.5
ENSMUST00000113838.1
Heph

hephaestin

chr7_-_115824699 20.718 ENSMUST00000169129.1
Sox6
SRY-box containing gene 6
chr15_+_25773985 20.272 ENSMUST00000125667.1
Myo10
myosin X
chr1_+_51289106 19.890 ENSMUST00000051572.6
Sdpr
serum deprivation response
chr1_+_43730593 19.887 ENSMUST00000027217.8
1500015O10Rik
RIKEN cDNA 1500015O10 gene
chr10_-_128704978 19.614 ENSMUST00000026416.7
ENSMUST00000026415.7
Cdk2

cyclin-dependent kinase 2

chr11_+_70700606 19.416 ENSMUST00000137119.2
Kif1c
kinesin family member 1C
chr8_-_105966038 19.358 ENSMUST00000116429.2
ENSMUST00000034370.9
Slc12a4

solute carrier family 12, member 4

chr13_-_81570640 19.345 ENSMUST00000109565.2
Gpr98
G protein-coupled receptor 98
chr1_-_120120138 19.257 ENSMUST00000112648.1
ENSMUST00000128408.1
Dbi

diazepam binding inhibitor

chr19_-_12765447 19.125 ENSMUST00000112933.1
Cntf
ciliary neurotrophic factor
chr3_+_37639945 19.039 ENSMUST00000108109.1
ENSMUST00000038569.1
Spry1

sprouty homolog 1 (Drosophila)

chr1_+_104768510 19.005 ENSMUST00000062528.8
Cdh20
cadherin 20
chr1_+_74391479 18.958 ENSMUST00000027367.7
Ctdsp1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr10_-_13324250 18.774 ENSMUST00000105543.1
Phactr2
phosphatase and actin regulator 2
chr14_+_46882854 18.520 ENSMUST00000022386.8
ENSMUST00000100672.3
Samd4

sterile alpha motif domain containing 4

chr7_-_19698383 18.363 ENSMUST00000173739.1
Apoe
apolipoprotein E
chr6_+_29694204 18.136 ENSMUST00000046750.7
ENSMUST00000115250.3
Tspan33

tetraspanin 33

chr6_+_104492790 18.059 ENSMUST00000161446.1
ENSMUST00000161070.1
ENSMUST00000089215.5
Cntn6


contactin 6


chr17_+_47593444 17.855 ENSMUST00000182209.1
Ccnd3
cyclin D3
chr3_+_37639985 17.530 ENSMUST00000108107.1
Spry1
sprouty homolog 1 (Drosophila)
chr9_+_44101722 17.421 ENSMUST00000161703.1
ENSMUST00000161381.1
ENSMUST00000034654.7
Mfrp


membrane-type frizzled-related protein


chr6_+_88724828 17.375 ENSMUST00000089449.2
Mgll
monoglyceride lipase
chr14_-_69284982 17.082 ENSMUST00000183882.1
ENSMUST00000037064.4
Slc25a37

solute carrier family 25, member 37

chr19_+_46305682 16.887 ENSMUST00000111881.2
Nfkb2
nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100
chr4_-_134018829 16.752 ENSMUST00000051674.2
Lin28a
lin-28 homolog A (C. elegans)
chr17_-_71002488 16.553 ENSMUST00000148960.1
Myl12a
myosin, light chain 12A, regulatory, non-sarcomeric
chr13_+_112464070 16.428 ENSMUST00000183663.1
ENSMUST00000184311.1
ENSMUST00000183886.1
Il6st


interleukin 6 signal transducer


chr6_+_146888481 16.310 ENSMUST00000016631.7
ENSMUST00000111623.2
Ppfibp1

PTPRF interacting protein, binding protein 1 (liprin beta 1)

chr11_+_100415697 16.276 ENSMUST00000001595.3
Fkbp10
FK506 binding protein 10
chr8_+_57511833 16.242 ENSMUST00000067925.6
Hmgb2
high mobility group box 2
chr7_-_65370908 16.125 ENSMUST00000032729.6
Tjp1
tight junction protein 1
chr18_-_60501983 15.782 ENSMUST00000042710.6
Smim3
small integral membrane protein 3
chr19_-_4439388 15.653 ENSMUST00000117462.1
ENSMUST00000048197.3
Rhod

ras homolog gene family, member D

chr7_+_51880312 15.595 ENSMUST00000145049.1
Gas2
growth arrest specific 2
chr19_-_23448322 15.489 ENSMUST00000036069.6
Mamdc2
MAM domain containing 2
chr1_+_169928648 15.182 ENSMUST00000094348.3
1700084C01Rik
RIKEN cDNA 1700084C01 gene
chr11_+_100415722 15.008 ENSMUST00000107400.2
Fkbp10
FK506 binding protein 10
chr14_-_48667508 14.989 ENSMUST00000144465.1
ENSMUST00000133479.1
ENSMUST00000119070.1
ENSMUST00000152018.1
Otx2



orthodenticle homolog 2 (Drosophila)



chr2_-_73485733 14.947 ENSMUST00000102680.1
Wipf1
WAS/WASL interacting protein family, member 1
chr6_+_82041623 14.903 ENSMUST00000042974.8
Eva1a
eva-1 homolog A (C. elegans)
chr10_-_128589650 14.888 ENSMUST00000082059.6
Erbb3
v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
chr2_-_156839790 14.655 ENSMUST00000134838.1
ENSMUST00000137463.1
ENSMUST00000149275.2
Gm14230


predicted gene 14230


chr10_+_126978690 14.655 ENSMUST00000105256.2
Ctdsp2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr6_+_17306335 14.594 ENSMUST00000007799.6
ENSMUST00000115456.1
ENSMUST00000115455.2
ENSMUST00000130505.1
Cav1



caveolin 1, caveolae protein



chrX_-_142306170 14.567 ENSMUST00000134825.2
Kcne1l
potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene
chr12_+_75308308 14.462 ENSMUST00000118602.1
ENSMUST00000118966.1
ENSMUST00000055390.5
Rhoj


ras homolog gene family, member J


chr2_-_92370999 14.388 ENSMUST00000176810.1
ENSMUST00000090582.4
Gyltl1b

glycosyltransferase-like 1B

chrX_+_139217166 14.321 ENSMUST00000166444.1
ENSMUST00000170671.1
ENSMUST00000113041.2
ENSMUST00000113042.2
Mum1l1



melanoma associated antigen (mutated) 1-like 1



chr2_+_52038005 14.223 ENSMUST00000065927.5
Tnfaip6
tumor necrosis factor alpha induced protein 6
chr6_-_37442095 14.161 ENSMUST00000041093.5
Creb3l2
cAMP responsive element binding protein 3-like 2
chr9_+_35421541 13.893 ENSMUST00000119129.2
Cdon
cell adhesion molecule-related/down-regulated by oncogenes
chr7_-_31054815 13.850 ENSMUST00000071697.4
ENSMUST00000108110.3
Fxyd1

FXYD domain-containing ion transport regulator 1

chr3_-_101110278 13.738 ENSMUST00000102694.3
Ptgfrn
prostaglandin F2 receptor negative regulator
chr17_+_88626569 13.719 ENSMUST00000150023.1
Ston1
stonin 1
chr2_-_164857542 13.629 ENSMUST00000109316.1
ENSMUST00000156255.1
ENSMUST00000128110.1
ENSMUST00000109317.3
Pltp



phospholipid transfer protein



chr9_-_79718631 13.408 ENSMUST00000180083.1
Col12a1
collagen, type XII, alpha 1
chrX_+_10717451 13.316 ENSMUST00000156321.1
Mid1ip1
Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish))
chrX_+_10717390 13.258 ENSMUST00000115524.1
ENSMUST00000008179.6
Mid1ip1

Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish))

chr5_+_77265454 13.225 ENSMUST00000080359.5
Rest
RE1-silencing transcription factor
chr13_-_3893556 12.913 ENSMUST00000099946.4
Net1
neuroepithelial cell transforming gene 1
chr9_-_79718518 12.901 ENSMUST00000071750.6
Col12a1
collagen, type XII, alpha 1
chr1_+_12692430 12.768 ENSMUST00000180062.1
ENSMUST00000177608.1
Sulf1

sulfatase 1

chr9_-_15627910 12.744 ENSMUST00000152377.1
ENSMUST00000115593.3
Ccdc67

coiled-coil domain containing 67

chr19_+_8989277 12.633 ENSMUST00000092955.3
ENSMUST00000092956.2
Ahnak

AHNAK nucleoprotein (desmoyokin)

chr11_-_69880971 12.629 ENSMUST00000050555.3
Kctd11
potassium channel tetramerisation domain containing 11
chr6_+_29433248 12.502 ENSMUST00000101617.2
ENSMUST00000065090.5
Flnc

filamin C, gamma

chr17_+_47593516 12.494 ENSMUST00000182874.1
Ccnd3
cyclin D3
chr9_-_67049143 12.405 ENSMUST00000113687.1
ENSMUST00000113693.1
ENSMUST00000113701.1
ENSMUST00000034928.5
ENSMUST00000113685.3
ENSMUST00000030185.4
ENSMUST00000050905.9
ENSMUST00000113705.1
ENSMUST00000113697.1
ENSMUST00000113707.2
Tpm1









tropomyosin 1, alpha









chr9_-_79718720 12.238 ENSMUST00000121227.1
Col12a1
collagen, type XII, alpha 1
chr2_-_164857671 12.104 ENSMUST00000059954.7
Pltp
phospholipid transfer protein
chr17_-_35702040 12.051 ENSMUST00000166980.2
ENSMUST00000145900.1
Ddr1

discoidin domain receptor family, member 1

chr5_+_77266196 11.985 ENSMUST00000113449.1
Rest
RE1-silencing transcription factor
chr2_-_92371039 11.919 ENSMUST00000068586.6
Gyltl1b
glycosyltransferase-like 1B
chr6_+_29735667 11.783 ENSMUST00000001812.4
Smo
smoothened homolog (Drosophila)
chr17_+_88626549 11.613 ENSMUST00000163588.1
ENSMUST00000064035.6
Ston1

stonin 1

chr4_+_98546710 11.532 ENSMUST00000102792.3
Inadl
InaD-like (Drosophila)
chr4_+_133176336 11.500 ENSMUST00000105912.1
Wasf2
WAS protein family, member 2
chr17_-_35702297 11.499 ENSMUST00000135078.1
Ddr1
discoidin domain receptor family, member 1
chr16_-_89508313 11.421 ENSMUST00000056118.2
Krtap7-1
keratin associated protein 7-1
chr4_+_141301228 11.287 ENSMUST00000006614.2
Epha2
Eph receptor A2
chr16_-_46155077 11.272 ENSMUST00000059524.5
Gm4737
predicted gene 4737
chr11_+_62077018 11.210 ENSMUST00000092415.5
Specc1
sperm antigen with calponin homology and coiled-coil domains 1
chr16_-_91069142 11.104 ENSMUST00000035689.1
ENSMUST00000114076.1
4932438H23Rik

RIKEN cDNA 4932438H23 gene

chr13_-_74807913 10.883 ENSMUST00000065629.4
Cast
calpastatin
chr9_-_15627897 10.616 ENSMUST00000045513.6
Ccdc67
coiled-coil domain containing 67
chr2_-_92370968 10.530 ENSMUST00000176774.1
Gyltl1b
glycosyltransferase-like 1B
chr9_-_67539392 10.426 ENSMUST00000039662.8
Tln2
talin 2
chr2_+_19658055 10.376 ENSMUST00000052168.4
Otud1
OTU domain containing 1
chr17_-_35701937 10.273 ENSMUST00000155628.1
Ddr1
discoidin domain receptor family, member 1
chr11_-_115808068 10.252 ENSMUST00000132780.1
Caskin2
CASK-interacting protein 2
chr6_+_17307040 10.122 ENSMUST00000123439.1
Cav1
caveolin 1, caveolae protein
chr4_+_98546919 10.118 ENSMUST00000030290.7
Inadl
InaD-like (Drosophila)
chr9_-_95815389 10.108 ENSMUST00000119760.1
Pls1
plastin 1 (I-isoform)
chr6_+_29433131 9.827 ENSMUST00000090474.4
Flnc
filamin C, gamma
chr17_-_28350747 9.786 ENSMUST00000080572.7
ENSMUST00000156862.1
Tead3

TEA domain family member 3

chr2_-_73486456 9.660 ENSMUST00000141264.1
Wipf1
WAS/WASL interacting protein family, member 1
chr3_-_116424007 9.549 ENSMUST00000090464.4
Cdc14a
CDC14 cell division cycle 14A
chr1_+_165769392 9.524 ENSMUST00000040298.4
Creg1
cellular repressor of E1A-stimulated genes 1
chrX_-_49788204 9.516 ENSMUST00000114893.1
Igsf1
immunoglobulin superfamily, member 1
chr3_-_116423930 9.441 ENSMUST00000106491.2
Cdc14a
CDC14 cell division cycle 14A
chr6_+_83034173 9.316 ENSMUST00000000707.2
ENSMUST00000101257.3
Loxl3

lysyl oxidase-like 3

chr14_-_69503220 9.250 ENSMUST00000180059.2
Gm21464
predicted gene, 21464
chr4_-_97778042 9.239 ENSMUST00000146447.1
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr9_-_96437434 9.196 ENSMUST00000070500.2
BC043934
cDNA sequence BC043934
chr17_-_28350600 9.122 ENSMUST00000114799.1
Tead3
TEA domain family member 3
chr14_-_57746044 9.096 ENSMUST00000173990.1
ENSMUST00000022531.7
Lats2

large tumor suppressor 2

chr8_+_14911663 9.030 ENSMUST00000084207.5
ENSMUST00000161162.1
ENSMUST00000110800.2
Arhgef10


Rho guanine nucleotide exchange factor (GEF) 10


chr14_-_69503316 8.995 ENSMUST00000179116.2
Gm21464
predicted gene, 21464
chr9_+_109095427 8.963 ENSMUST00000072093.6
Plxnb1
plexin B1
chr3_-_135691512 8.944 ENSMUST00000029812.7
Nfkb1
nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
chr7_-_4164796 8.889 ENSMUST00000076831.6
Cdc42ep5
CDC42 effector protein (Rho GTPase binding) 5
chr7_-_90129339 8.760 ENSMUST00000181189.1
2310010J17Rik
RIKEN cDNA 2310010J17 gene
chr10_+_4710119 8.644 ENSMUST00000105588.1
ENSMUST00000105589.1
Esr1

estrogen receptor 1 (alpha)

chr7_-_4164442 8.588 ENSMUST00000140410.1
ENSMUST00000143825.1
Cdc42ep5

CDC42 effector protein (Rho GTPase binding) 5

chr15_+_101266839 8.573 ENSMUST00000023779.6
Nr4a1
nuclear receptor subfamily 4, group A, member 1
chr19_-_42129043 8.502 ENSMUST00000018965.3
Avpi1
arginine vasopressin-induced 1
chr6_-_23839137 8.284 ENSMUST00000166458.2
ENSMUST00000142913.2
ENSMUST00000115357.1
ENSMUST00000069074.7
ENSMUST00000115361.2
ENSMUST00000018122.7
ENSMUST00000115355.1
ENSMUST00000115356.2
Cadps2







Ca2+-dependent activator protein for secretion 2







chr2_+_156840077 8.223 ENSMUST00000081335.6
ENSMUST00000073352.3
Tgif2

TGFB-induced factor homeobox 2

chr17_-_15375969 8.105 ENSMUST00000014917.7
Dll1
delta-like 1 (Drosophila)
chr4_-_154636831 8.087 ENSMUST00000030902.6
ENSMUST00000105637.1
ENSMUST00000070313.7
ENSMUST00000105636.1
ENSMUST00000105638.2
ENSMUST00000097759.2
ENSMUST00000124771.1
Prdm16






PR domain containing 16






chr13_-_83729544 8.077 ENSMUST00000181705.1
Gm26803
predicted gene, 26803
chr10_-_128176568 8.070 ENSMUST00000092033.2
Rbms2
RNA binding motif, single stranded interacting protein 2
chr16_+_77014069 8.025 ENSMUST00000023580.6
Usp25
ubiquitin specific peptidase 25
chr7_-_132813799 8.000 ENSMUST00000097998.2
Fam53b
family with sequence similarity 53, member B
chr6_+_34598530 7.914 ENSMUST00000115027.1
ENSMUST00000115026.1
Cald1

caldesmon 1

chr5_+_24426831 7.828 ENSMUST00000155598.1
Slc4a2
solute carrier family 4 (anion exchanger), member 2
chr17_-_71002017 7.710 ENSMUST00000128179.1
ENSMUST00000150456.1
Myl12a

myosin, light chain 12A, regulatory, non-sarcomeric

chr3_+_88364548 7.609 ENSMUST00000147948.1
ENSMUST00000147991.1
Paqr6

progestin and adipoQ receptor family member VI

chr6_+_34598500 7.596 ENSMUST00000079391.3
ENSMUST00000142512.1
Cald1

caldesmon 1

chrX_+_101254528 7.569 ENSMUST00000062000.4
Foxo4
forkhead box O4
chr6_+_88724667 7.486 ENSMUST00000163271.1
Mgll
monoglyceride lipase
chr9_+_13765970 7.440 ENSMUST00000152532.1
Mtmr2
myotubularin related protein 2
chr10_-_89443888 7.397 ENSMUST00000099374.2
ENSMUST00000105298.1
Gas2l3

growth arrest-specific 2 like 3

chr2_-_64097994 7.356 ENSMUST00000131615.2
Fign
fidgetin
chr4_+_89137122 7.293 ENSMUST00000058030.7
Mtap
methylthioadenosine phosphorylase
chr11_+_44519405 7.288 ENSMUST00000101327.2
Rnf145
ring finger protein 145
chr12_-_73113407 6.967 ENSMUST00000175693.1
Six4
sine oculis-related homeobox 4
chr8_+_123186235 6.965 ENSMUST00000019422.4
Dpep1
dipeptidase 1 (renal)
chr18_+_82554463 6.921 ENSMUST00000062446.7
ENSMUST00000102812.4
ENSMUST00000075372.5
ENSMUST00000080658.4
ENSMUST00000152071.1
ENSMUST00000114674.3
ENSMUST00000142850.1
ENSMUST00000133193.1
ENSMUST00000123251.1
ENSMUST00000153478.1
ENSMUST00000132369.1
Mbp










myelin basic protein










chr6_+_17306415 6.613 ENSMUST00000150901.1
Cav1
caveolin 1, caveolae protein
chr1_+_4808237 6.598 ENSMUST00000131119.1
Lypla1
lysophospholipase 1
chr2_+_72285637 6.596 ENSMUST00000090824.5
ENSMUST00000135469.1
Zak

sterile alpha motif and leucine zipper containing kinase AZK

chr1_+_106171752 6.495 ENSMUST00000061047.6
Phlpp1
PH domain and leucine rich repeat protein phosphatase 1
chr2_-_35432552 6.450 ENSMUST00000079424.4
Ggta1
glycoprotein galactosyltransferase alpha 1, 3
chr4_+_154237525 6.373 ENSMUST00000152159.1
Megf6
multiple EGF-like-domains 6
chr6_+_135065651 6.363 ENSMUST00000050104.7
Gprc5a
G protein-coupled receptor, family C, group 5, member A
chr16_+_20674111 6.317 ENSMUST00000151679.1
Eif4g1
eukaryotic translation initiation factor 4, gamma 1
chr2_+_31572651 6.310 ENSMUST00000113482.1
Fubp3
far upstream element (FUSE) binding protein 3
chr18_-_47333311 5.880 ENSMUST00000126684.1
ENSMUST00000156422.1
Sema6a

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A

chr1_-_82291370 5.830 ENSMUST00000069799.2
Irs1
insulin receptor substrate 1
chr11_-_100970887 5.826 ENSMUST00000060792.5
Ptrf
polymerase I and transcript release factor

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
53.3 213.3 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
19.1 57.3 GO:0044849 estrous cycle(GO:0044849)
17.0 85.1 GO:0035331 negative regulation of hippo signaling(GO:0035331)
16.6 49.8 GO:2001139 negative regulation of postsynaptic membrane organization(GO:1901627) negative regulation of dendritic spine maintenance(GO:1902951) negative regulation of phospholipid efflux(GO:1902999) regulation of lipid transport across blood brain barrier(GO:1903000) negative regulation of lipid transport across blood brain barrier(GO:1903001) positive regulation of lipid transport across blood brain barrier(GO:1903002) negative regulation of phospholipid transport(GO:2001139)
16.4 49.1 GO:0035622 intrahepatic bile duct development(GO:0035622) renal vesicle induction(GO:0072034)
14.9 44.6 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
14.6 72.9 GO:0032346 positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349) regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
11.0 88.1 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
10.5 63.0 GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
10.3 41.0 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
10.0 70.2 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
9.5 57.2 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
8.9 35.6 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
8.9 26.7 GO:1904395 positive regulation of postsynaptic membrane organization(GO:1901628) regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
7.7 30.9 GO:0048143 astrocyte activation(GO:0048143)
7.3 36.6 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
6.4 25.7 GO:0042360 vitamin E metabolic process(GO:0042360)
6.3 25.2 GO:2000705 regulation of dense core granule biogenesis(GO:2000705)
6.3 31.3 GO:1903598 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) positive regulation of gap junction assembly(GO:1903598)
6.2 49.4 GO:0016081 synaptic vesicle docking(GO:0016081)
5.8 23.4 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
5.8 63.3 GO:0060710 chorio-allantoic fusion(GO:0060710)
5.7 28.6 GO:0038018 Wnt receptor catabolic process(GO:0038018)
5.5 38.5 GO:0015840 urea transport(GO:0015840) urea transmembrane transport(GO:0071918)
5.5 16.4 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165) regulation of interleukin-6-mediated signaling pathway(GO:0070103) negative regulation of interleukin-6-mediated signaling pathway(GO:0070104)
5.4 38.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
5.2 62.6 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
4.6 13.9 GO:1903795 regulation of inorganic anion transmembrane transport(GO:1903795)
4.3 8.6 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745)
3.9 19.6 GO:0032298 positive regulation of DNA-dependent DNA replication initiation(GO:0032298)
3.9 19.3 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
3.8 11.3 GO:0014028 notochord formation(GO:0014028) negative regulation of lymphangiogenesis(GO:1901491)
3.6 7.3 GO:0006166 purine ribonucleoside salvage(GO:0006166)
3.6 14.6 GO:0099624 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372) atrial cardiac muscle cell membrane repolarization(GO:0099624)
3.6 24.9 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
3.4 10.1 GO:0001951 intestinal D-glucose absorption(GO:0001951) terminal web assembly(GO:1902896)
3.2 38.9 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
3.2 12.8 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
3.2 12.8 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
3.0 9.1 GO:0001827 inner cell mass cell fate commitment(GO:0001827)
3.0 8.9 GO:0060558 regulation of calcidiol 1-monooxygenase activity(GO:0060558)
3.0 8.9 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
2.7 54.4 GO:0001946 lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303)
2.7 19.0 GO:0000022 mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
2.7 8.1 GO:0060853 arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) endothelial cell fate specification(GO:0060847) Notch signaling pathway involved in arterial endothelial cell fate commitment(GO:0060853) blood vessel endothelial cell fate specification(GO:0097101)
2.7 26.6 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
2.6 7.9 GO:1904685 positive regulation of metalloendopeptidase activity(GO:1904685)
2.6 20.9 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
2.6 10.3 GO:0046084 adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
2.5 35.2 GO:0035269 protein O-linked mannosylation(GO:0035269)
2.5 19.9 GO:0070314 G1 to G0 transition(GO:0070314)
2.5 7.4 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
2.5 22.3 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
2.5 4.9 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
2.4 36.4 GO:0071803 positive regulation of podosome assembly(GO:0071803)
2.3 16.2 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
2.1 21.3 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
2.1 21.1 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
2.1 18.9 GO:0055059 asymmetric neuroblast division(GO:0055059)
2.1 20.7 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
2.1 12.4 GO:0003062 regulation of heart rate by chemical signal(GO:0003062) positive regulation of heart rate by epinephrine(GO:0003065)
2.0 21.5 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
1.9 7.6 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
1.9 5.6 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
1.9 16.8 GO:0010587 miRNA catabolic process(GO:0010587)
1.8 14.5 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
1.8 12.6 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
1.7 15.5 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
1.6 6.5 GO:0033580 protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125)
1.6 4.8 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
1.6 10.9 GO:0007343 egg activation(GO:0007343)
1.6 21.8 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
1.5 4.6 GO:0003223 ventricular compact myocardium morphogenesis(GO:0003223)
1.5 2.9 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
1.5 16.1 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
1.4 71.2 GO:0032611 interleukin-1 beta production(GO:0032611)
1.4 29.0 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
1.4 14.9 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
1.3 4.0 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
1.3 6.6 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
1.3 6.5 GO:0002667 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) negative regulation of protein kinase C signaling(GO:0090038)
1.3 16.9 GO:0002467 germinal center formation(GO:0002467)
1.3 24.6 GO:0051127 positive regulation of actin nucleation(GO:0051127)
1.2 17.0 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
1.2 8.1 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
1.1 9.2 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
1.1 4.5 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
1.1 5.4 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
1.0 3.1 GO:0016095 polyprenol catabolic process(GO:0016095)
1.0 12.9 GO:0051451 myoblast migration(GO:0051451)
1.0 38.7 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
1.0 5.8 GO:0070094 positive regulation of glucagon secretion(GO:0070094)
0.9 20.8 GO:0006825 copper ion transport(GO:0006825)
0.8 5.8 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361) termination of RNA polymerase I transcription(GO:0006363)
0.8 11.5 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.8 21.5 GO:0006270 DNA replication initiation(GO:0006270)
0.8 3.8 GO:0071205 clustering of voltage-gated potassium channels(GO:0045163) protein localization to juxtaparanode region of axon(GO:0071205)
0.8 13.7 GO:0034389 lipid particle organization(GO:0034389)
0.8 38.0 GO:0042058 regulation of epidermal growth factor receptor signaling pathway(GO:0042058)
0.7 5.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.7 4.5 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.7 33.6 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.6 3.2 GO:0032836 glomerular basement membrane development(GO:0032836)
0.6 18.7 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.6 5.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.6 5.9 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.6 2.3 GO:0042938 dipeptide transport(GO:0042938)
0.6 8.0 GO:1904293 negative regulation of ERAD pathway(GO:1904293)
0.6 18.1 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.6 34.9 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.6 2.8 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.6 5.0 GO:0034776 response to histamine(GO:0034776) cellular response to histamine(GO:0071420)
0.5 3.2 GO:0035743 CD4-positive, alpha-beta T cell cytokine production(GO:0035743) T-helper 2 cell cytokine production(GO:0035745)
0.5 15.7 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.5 5.4 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.5 3.2 GO:2000210 positive regulation of anoikis(GO:2000210)
0.5 38.9 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.5 2.5 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.5 24.3 GO:0072661 protein targeting to plasma membrane(GO:0072661)
0.5 8.2 GO:0038092 nodal signaling pathway(GO:0038092)
0.5 3.8 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.5 8.6 GO:0035767 endothelial cell chemotaxis(GO:0035767)
0.4 4.5 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.4 1.8 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.4 6.2 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.4 3.1 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.4 8.3 GO:0016082 synaptic vesicle priming(GO:0016082)
0.4 7.0 GO:0050667 homocysteine metabolic process(GO:0050667)
0.4 1.7 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110) regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.4 2.2 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.4 5.5 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.3 9.0 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.3 2.0 GO:0035988 chondrocyte proliferation(GO:0035988)
0.3 1.6 GO:0006532 aspartate biosynthetic process(GO:0006532)
0.3 2.1 GO:0000103 sulfate assimilation(GO:0000103)
0.3 16.3 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.3 12.0 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.3 5.9 GO:0044381 glucose import in response to insulin stimulus(GO:0044381) regulation of glucose import in response to insulin stimulus(GO:2001273)
0.3 5.5 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.3 29.6 GO:0007050 cell cycle arrest(GO:0007050)
0.3 2.0 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.3 25.9 GO:0070374 positive regulation of ERK1 and ERK2 cascade(GO:0070374)
0.2 24.0 GO:0048706 embryonic skeletal system development(GO:0048706)
0.2 11.6 GO:0048747 muscle fiber development(GO:0048747)
0.2 14.2 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.2 2.7 GO:0033622 integrin activation(GO:0033622)
0.2 7.6 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.2 13.2 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.2 3.1 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.2 10.6 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.2 2.8 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.2 4.8 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.2 0.7 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.2 15.8 GO:0045727 positive regulation of translation(GO:0045727)
0.2 4.8 GO:0033014 porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014)
0.2 1.4 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.1 12.6 GO:0043484 regulation of RNA splicing(GO:0043484)
0.1 1.9 GO:0060441 epithelial tube branching involved in lung morphogenesis(GO:0060441)
0.1 0.4 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.1 2.1 GO:0003229 ventricular cardiac muscle tissue development(GO:0003229)
0.1 1.3 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 2.2 GO:0010107 potassium ion import(GO:0010107)
0.1 2.9 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.1 2.4 GO:1901343 negative regulation of angiogenesis(GO:0016525) negative regulation of vasculature development(GO:1901343) negative regulation of blood vessel morphogenesis(GO:2000181)
0.1 4.4 GO:0051453 regulation of intracellular pH(GO:0051453)
0.1 3.9 GO:1900181 negative regulation of protein localization to nucleus(GO:1900181)
0.1 0.4 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.1 5.2 GO:0050821 protein stabilization(GO:0050821)
0.0 1.0 GO:0016572 histone phosphorylation(GO:0016572)
0.0 3.8 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.0 3.6 GO:0017148 negative regulation of translation(GO:0017148)
0.0 3.2 GO:0009636 response to toxic substance(GO:0009636)
0.0 1.2 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 3.2 GO:0006813 potassium ion transport(GO:0006813)
0.0 3.2 GO:0008360 regulation of cell shape(GO:0008360)
0.0 2.3 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 3.2 GO:0006364 rRNA processing(GO:0006364)
0.0 0.9 GO:0008589 regulation of smoothened signaling pathway(GO:0008589)
0.0 0.4 GO:0017145 stem cell division(GO:0017145)
0.0 10.1 GO:0055114 oxidation-reduction process(GO:0055114)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
21.0 63.0 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
18.2 72.9 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
16.6 49.8 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
12.8 38.5 GO:0005595 collagen type XII trimer(GO:0005595) anchoring collagen complex(GO:0030934)
8.7 35.0 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
6.4 19.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
5.5 16.4 GO:0005896 interleukin-6 receptor complex(GO:0005896)
4.4 57.3 GO:0043219 lateral loop(GO:0043219)
3.9 201.4 GO:0005801 cis-Golgi network(GO:0005801)
3.8 53.9 GO:0005614 interstitial matrix(GO:0005614)
3.7 25.8 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
3.0 21.1 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
2.9 23.4 GO:0098536 deuterosome(GO:0098536)
2.4 11.8 GO:0044294 dendritic growth cone(GO:0044294)
2.4 49.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
2.1 31.3 GO:0002080 acrosomal membrane(GO:0002080)
2.0 10.1 GO:1990357 terminal web(GO:1990357)
2.0 16.1 GO:0046581 intercellular canaliculus(GO:0046581)
2.0 19.6 GO:0000805 X chromosome(GO:0000805)
1.9 5.8 GO:0005899 insulin receptor complex(GO:0005899)
1.9 26.7 GO:0016600 flotillin complex(GO:0016600)
1.9 5.6 GO:0034679 integrin alpha2-beta1 complex(GO:0034666) integrin alpha3-beta1 complex(GO:0034667) integrin alpha9-beta1 complex(GO:0034679)
1.8 29.6 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
1.8 25.1 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
1.8 24.9 GO:0043196 varicosity(GO:0043196)
1.8 26.3 GO:0016460 myosin II complex(GO:0016460)
1.7 6.9 GO:0033269 internode region of axon(GO:0033269)
1.7 15.5 GO:0030478 actin cap(GO:0030478)
1.6 7.9 GO:0031523 Myb complex(GO:0031523)
1.5 36.4 GO:0002102 podosome(GO:0002102)
1.4 12.4 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
1.2 12.8 GO:0002116 semaphorin receptor complex(GO:0002116)
1.2 10.4 GO:0005916 fascia adherens(GO:0005916)
1.1 80.1 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
1.1 52.1 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
1.1 3.2 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.9 6.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.9 11.5 GO:0031209 SCAR complex(GO:0031209)
0.8 4.8 GO:0008091 spectrin(GO:0008091)
0.8 21.1 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.8 3.8 GO:0008623 CHRAC(GO:0008623)
0.7 32.7 GO:0016459 myosin complex(GO:0016459)
0.7 16.1 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.7 43.1 GO:0005871 kinesin complex(GO:0005871)
0.6 263.8 GO:0005925 focal adhesion(GO:0005925)
0.6 5.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.5 4.9 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.5 8.6 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.4 35.6 GO:0005604 basement membrane(GO:0005604)
0.4 31.7 GO:0017053 transcriptional repressor complex(GO:0017053)
0.4 155.6 GO:0005667 transcription factor complex(GO:0005667)
0.4 6.2 GO:0010369 chromocenter(GO:0010369)
0.4 2.2 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.4 30.2 GO:0005901 caveola(GO:0005901)
0.3 3.8 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.3 3.6 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.3 8.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.3 51.8 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.3 58.1 GO:0016323 basolateral plasma membrane(GO:0016323)
0.3 24.3 GO:0030018 Z disc(GO:0030018)
0.3 5.0 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.3 1.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.2 11.4 GO:0005882 intermediate filament(GO:0005882)
0.2 10.2 GO:0031985 Golgi cisterna(GO:0031985)
0.2 25.7 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.2 4.5 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.2 55.7 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.2 1.3 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.2 18.8 GO:0000922 spindle pole(GO:0000922)
0.2 14.3 GO:0005884 actin filament(GO:0005884)
0.2 8.1 GO:0005912 adherens junction(GO:0005912)
0.2 4.7 GO:0001772 immunological synapse(GO:0001772)
0.2 2.0 GO:0005922 connexon complex(GO:0005922)
0.2 8.3 GO:0042734 presynaptic membrane(GO:0042734)
0.1 0.4 GO:0097227 sperm annulus(GO:0097227)
0.1 1.3 GO:0034709 methylosome(GO:0034709)
0.1 15.5 GO:0000793 condensed chromosome(GO:0000793)
0.1 4.1 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 6.8 GO:0000502 proteasome complex(GO:0000502)
0.1 0.4 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 6.5 GO:0016363 nuclear matrix(GO:0016363)
0.1 123.8 GO:0005829 cytosol(GO:0005829)
0.1 25.6 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.1 4.6 GO:0005923 bicellular tight junction(GO:0005923)
0.1 3.7 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1 2.1 GO:0045171 intercellular bridge(GO:0045171)
0.1 4.7 GO:0030426 growth cone(GO:0030426)
0.1 3.0 GO:0031225 anchored component of membrane(GO:0031225)
0.1 30.2 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 2.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 11.2 GO:0005768 endosome(GO:0005768)
0.0 8.9 GO:0005874 microtubule(GO:0005874)
0.0 0.7 GO:0016592 mediator complex(GO:0016592)
0.0 1.5 GO:0005643 nuclear pore(GO:0005643)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
16.6 49.8 GO:0046911 hydroxyapatite binding(GO:0046848) metal chelating activity(GO:0046911) phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
15.8 63.0 GO:0004859 phospholipase inhibitor activity(GO:0004859) phospholipase A2 inhibitor activity(GO:0019834)
13.4 295.9 GO:0005520 insulin-like growth factor binding(GO:0005520)
10.3 72.2 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
8.1 72.9 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
7.8 77.7 GO:0030274 LIM domain binding(GO:0030274)
7.4 36.8 GO:0018121 imidazoleglycerol-phosphate synthase activity(GO:0000107) NAD(P)-cysteine ADP-ribosyltransferase activity(GO:0018071) NAD(P)-asparagine ADP-ribosyltransferase activity(GO:0018121) NAD(P)-serine ADP-ribosyltransferase activity(GO:0018127) 7-cyano-7-deazaguanine tRNA-ribosyltransferase activity(GO:0043867) purine deoxyribosyltransferase activity(GO:0044102)
6.4 38.5 GO:0015265 urea channel activity(GO:0015265)
6.3 31.3 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
6.2 73.9 GO:0045294 alpha-catenin binding(GO:0045294)
5.7 45.4 GO:0018741 alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902)
5.5 16.4 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923) oncostatin-M receptor activity(GO:0004924)
5.1 35.6 GO:0043237 laminin-1 binding(GO:0043237)
4.8 29.0 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
4.8 19.3 GO:0030156 benzodiazepine receptor binding(GO:0030156)
4.8 19.1 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
4.5 49.1 GO:0097157 pre-mRNA intronic binding(GO:0097157)
4.4 57.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
4.3 38.9 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
4.2 20.8 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
3.7 33.6 GO:0008420 CTD phosphatase activity(GO:0008420)
3.4 75.5 GO:0017049 GTP-Rho binding(GO:0017049)
3.2 19.4 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
3.1 9.3 GO:0043912 D-lysine oxidase activity(GO:0043912)
2.9 11.8 GO:0005113 patched binding(GO:0005113)
2.9 14.6 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
2.9 8.6 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
2.4 7.3 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
2.1 24.9 GO:0047372 acylglycerol lipase activity(GO:0047372)
2.1 78.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
2.0 7.9 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
2.0 21.5 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
1.9 5.6 GO:0019960 C-X3-C chemokine binding(GO:0019960)
1.9 11.1 GO:0050786 RAGE receptor binding(GO:0050786)
1.8 38.7 GO:0004602 glutathione peroxidase activity(GO:0004602)
1.8 22.1 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
1.8 65.3 GO:0017091 AU-rich element binding(GO:0017091)
1.8 5.4 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
1.7 6.9 GO:0019911 structural constituent of myelin sheath(GO:0019911)
1.6 4.8 GO:0071862 protein phosphatase type 1 activator activity(GO:0071862)
1.5 88.1 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
1.5 5.8 GO:0042134 rRNA primary transcript binding(GO:0042134)
1.3 5.2 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
1.3 34.9 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
1.3 12.6 GO:0044548 S100 protein binding(GO:0044548)
1.2 19.6 GO:0035173 histone kinase activity(GO:0035173)
1.2 16.8 GO:0035198 miRNA binding(GO:0035198)
1.1 27.1 GO:0030506 ankyrin binding(GO:0030506)
1.1 18.5 GO:0030371 translation repressor activity(GO:0030371)
1.1 6.5 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
1.1 9.5 GO:0034711 inhibin binding(GO:0034711)
1.0 3.1 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) enone reductase activity(GO:0035671) cholestenone 5-alpha-reductase activity(GO:0047751)
1.0 9.9 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.9 12.8 GO:0017154 semaphorin receptor activity(GO:0017154)
0.9 10.9 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.9 8.1 GO:0030957 Tat protein binding(GO:0030957)
0.9 7.9 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.8 12.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.8 14.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.8 32.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.8 21.8 GO:0030332 cyclin binding(GO:0030332)
0.7 32.9 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.7 14.2 GO:0035497 cAMP response element binding(GO:0035497)
0.7 7.4 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.7 21.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.6 43.1 GO:0003777 microtubule motor activity(GO:0003777)
0.6 6.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.6 24.5 GO:0005109 frizzled binding(GO:0005109)
0.6 9.5 GO:0010181 FMN binding(GO:0010181)
0.6 11.3 GO:0005003 ephrin receptor activity(GO:0005003)
0.6 21.1 GO:0004407 histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.5 1.6 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.5 7.4 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.5 1.5 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.5 4.5 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.5 21.5 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.5 4.7 GO:0070097 delta-catenin binding(GO:0070097)
0.5 2.3 GO:0042895 antibiotic transporter activity(GO:0042895)
0.5 73.3 GO:0051015 actin filament binding(GO:0051015)
0.5 16.7 GO:0003774 motor activity(GO:0003774)
0.4 1.8 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.4 32.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.4 1.3 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.4 53.5 GO:0005539 glycosaminoglycan binding(GO:0005539)
0.4 8.0 GO:0032183 SUMO binding(GO:0032183)
0.4 8.1 GO:0033613 activating transcription factor binding(GO:0033613)
0.4 19.9 GO:0005080 protein kinase C binding(GO:0005080)
0.4 20.2 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.4 4.9 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.3 8.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.3 21.5 GO:0032947 protein complex scaffold(GO:0032947)
0.3 5.0 GO:0004890 GABA-A receptor activity(GO:0004890)
0.3 1.4 GO:0017166 vinculin binding(GO:0017166)
0.3 11.4 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.3 10.0 GO:0017080 sodium channel regulator activity(GO:0017080)
0.3 17.8 GO:0035254 glutamate receptor binding(GO:0035254)
0.3 27.3 GO:0030165 PDZ domain binding(GO:0030165)
0.2 3.8 GO:0017160 Ral GTPase binding(GO:0017160)
0.2 4.4 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.2 9.0 GO:0019894 kinesin binding(GO:0019894)
0.2 2.8 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.2 10.3 GO:0016831 carboxy-lyase activity(GO:0016831)
0.2 42.2 GO:0008022 protein C-terminus binding(GO:0008022)
0.2 39.9 GO:0003714 transcription corepressor activity(GO:0003714)
0.2 2.0 GO:0005243 gap junction channel activity(GO:0005243)
0.2 18.9 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.2 2.8 GO:0046965 retinoid X receptor binding(GO:0046965)
0.2 39.0 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.2 2.2 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.2 4.5 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 2.1 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.1 1.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 1.9 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 7.6 GO:0005496 steroid binding(GO:0005496)
0.1 2.9 GO:0005518 collagen binding(GO:0005518)
0.1 17.1 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 0.3 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 1.9 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.1 0.7 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.1 2.4 GO:0015631 tubulin binding(GO:0015631)
0.1 1.4 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 2.2 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 3.8 GO:0002020 protease binding(GO:0002020)
0.0 1.3 GO:0004697 protein kinase C activity(GO:0004697)
0.0 3.2 GO:0043851 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) rRNA (uridine-2'-O-)-methyltransferase activity(GO:0008650) rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383) selenocysteine methyltransferase activity(GO:0016205) rRNA (adenine) methyltransferase activity(GO:0016433) rRNA (cytosine) methyltransferase activity(GO:0016434) rRNA (guanine) methyltransferase activity(GO:0016435) 1-phenanthrol methyltransferase activity(GO:0018707) protein-arginine N5-methyltransferase activity(GO:0019702) dimethylarsinite methyltransferase activity(GO:0034541) 4,5-dihydroxybenzo(a)pyrene methyltransferase activity(GO:0034807) 1-hydroxypyrene methyltransferase activity(GO:0034931) 1-hydroxy-6-methoxypyrene methyltransferase activity(GO:0034933) demethylmenaquinone methyltransferase activity(GO:0043770) cobalt-precorrin-6B C5-methyltransferase activity(GO:0043776) cobalt-precorrin-7 C15-methyltransferase activity(GO:0043777) cobalt-precorrin-5B C1-methyltransferase activity(GO:0043780) cobalt-precorrin-3 C17-methyltransferase activity(GO:0043782) dimethylamine methyltransferase activity(GO:0043791) hydroxyneurosporene-O-methyltransferase activity(GO:0043803) tRNA (adenine-57, 58-N(1)-) methyltransferase activity(GO:0043827) methylamine-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043833) trimethylamine methyltransferase activity(GO:0043834) methanol-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043851) monomethylamine methyltransferase activity(GO:0043852) P-methyltransferase activity(GO:0051994) Se-methyltransferase activity(GO:0051995) 2-phytyl-1,4-naphthoquinone methyltransferase activity(GO:0052624) tRNA (uracil-2'-O-)-methyltransferase activity(GO:0052665) tRNA (cytosine-2'-O-)-methyltransferase activity(GO:0052666) phosphomethylethanolamine N-methyltransferase activity(GO:0052667) tRNA (cytosine-3-)-methyltransferase activity(GO:0052735) rRNA (cytosine-2'-O-)-methyltransferase activity(GO:0070677) rRNA (cytosine-N4-)-methyltransferase activity(GO:0071424) trihydroxyferuloyl spermidine O-methyltransferase activity(GO:0080012)
0.0 0.1 GO:0001849 opsonin binding(GO:0001846) complement component C1q binding(GO:0001849)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)
0.0 1.8 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 5.4 GO:0005525 GTP binding(GO:0005525)