Motif ID: Tead3_Tead4
Z-value: 3.575


Transcription factors associated with Tead3_Tead4:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Tead3 | ENSMUSG00000002249.11 | Tead3 |
Tead4 | ENSMUSG00000030353.9 | Tead4 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Tead3 | mm10_v2_chr17_-_28350600_28350681 | 0.69 | 4.1e-11 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 181 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
53.3 | 213.3 | GO:0070318 | positive regulation of G0 to G1 transition(GO:0070318) |
11.0 | 88.1 | GO:0007016 | cytoskeletal anchoring at plasma membrane(GO:0007016) |
17.0 | 85.1 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) |
14.6 | 72.9 | GO:0032346 | positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349) regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298) |
1.4 | 71.2 | GO:0032611 | interleukin-1 beta production(GO:0032611) |
10.0 | 70.2 | GO:0072257 | metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307) |
5.8 | 63.3 | GO:0060710 | chorio-allantoic fusion(GO:0060710) |
10.5 | 63.0 | GO:0032804 | negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804) |
5.2 | 62.6 | GO:0031274 | positive regulation of pseudopodium assembly(GO:0031274) |
19.1 | 57.3 | GO:0044849 | estrous cycle(GO:0044849) |
9.5 | 57.2 | GO:0007253 | cytoplasmic sequestering of NF-kappaB(GO:0007253) |
2.7 | 54.4 | GO:0001946 | lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303) |
16.6 | 49.8 | GO:2001139 | negative regulation of postsynaptic membrane organization(GO:1901627) negative regulation of dendritic spine maintenance(GO:1902951) negative regulation of phospholipid efflux(GO:1902999) regulation of lipid transport across blood brain barrier(GO:1903000) negative regulation of lipid transport across blood brain barrier(GO:1903001) positive regulation of lipid transport across blood brain barrier(GO:1903002) negative regulation of phospholipid transport(GO:2001139) |
6.2 | 49.4 | GO:0016081 | synaptic vesicle docking(GO:0016081) |
16.4 | 49.1 | GO:0035622 | intrahepatic bile duct development(GO:0035622) renal vesicle induction(GO:0072034) |
14.9 | 44.6 | GO:0003278 | apoptotic process involved in heart morphogenesis(GO:0003278) |
10.3 | 41.0 | GO:0046552 | eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552) |
3.2 | 38.9 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
0.5 | 38.9 | GO:0010811 | positive regulation of cell-substrate adhesion(GO:0010811) |
1.0 | 38.7 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 94 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 263.8 | GO:0005925 | focal adhesion(GO:0005925) |
3.9 | 201.4 | GO:0005801 | cis-Golgi network(GO:0005801) |
0.4 | 155.6 | GO:0005667 | transcription factor complex(GO:0005667) |
0.1 | 123.8 | GO:0005829 | cytosol(GO:0005829) |
1.1 | 80.1 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
18.2 | 72.9 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
21.0 | 63.0 | GO:1990667 | PCSK9-AnxA2 complex(GO:1990667) |
0.3 | 58.1 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
4.4 | 57.3 | GO:0043219 | lateral loop(GO:0043219) |
0.2 | 55.7 | GO:0005789 | endoplasmic reticulum membrane(GO:0005789) |
3.8 | 53.9 | GO:0005614 | interstitial matrix(GO:0005614) |
1.1 | 52.1 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
0.3 | 51.8 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
16.6 | 49.8 | GO:0034363 | intermediate-density lipoprotein particle(GO:0034363) |
2.4 | 49.4 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
0.7 | 43.1 | GO:0005871 | kinesin complex(GO:0005871) |
12.8 | 38.5 | GO:0005595 | collagen type XII trimer(GO:0005595) anchoring collagen complex(GO:0030934) |
1.5 | 36.4 | GO:0002102 | podosome(GO:0002102) |
0.4 | 35.6 | GO:0005604 | basement membrane(GO:0005604) |
8.7 | 35.0 | GO:0036454 | insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 129 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
13.4 | 295.9 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
1.5 | 88.1 | GO:0030971 | receptor tyrosine kinase binding(GO:0030971) |
2.1 | 78.2 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
7.8 | 77.7 | GO:0030274 | LIM domain binding(GO:0030274) |
3.4 | 75.5 | GO:0017049 | GTP-Rho binding(GO:0017049) |
6.2 | 73.9 | GO:0045294 | alpha-catenin binding(GO:0045294) |
0.5 | 73.3 | GO:0051015 | actin filament binding(GO:0051015) |
8.1 | 72.9 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
10.3 | 72.2 | GO:0004716 | receptor signaling protein tyrosine kinase activity(GO:0004716) |
1.8 | 65.3 | GO:0017091 | AU-rich element binding(GO:0017091) |
15.8 | 63.0 | GO:0004859 | phospholipase inhibitor activity(GO:0004859) phospholipase A2 inhibitor activity(GO:0019834) |
4.4 | 57.2 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
0.4 | 53.5 | GO:0005539 | glycosaminoglycan binding(GO:0005539) |
16.6 | 49.8 | GO:0046911 | hydroxyapatite binding(GO:0046848) metal chelating activity(GO:0046911) phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228) |
4.5 | 49.1 | GO:0097157 | pre-mRNA intronic binding(GO:0097157) |
5.7 | 45.4 | GO:0018741 | alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902) |
0.6 | 43.1 | GO:0003777 | microtubule motor activity(GO:0003777) |
0.2 | 42.2 | GO:0008022 | protein C-terminus binding(GO:0008022) |
0.2 | 39.9 | GO:0003714 | transcription corepressor activity(GO:0003714) |
0.2 | 39.0 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |