Motif ID: Tfap2a

Z-value: 1.113


Transcription factors associated with Tfap2a:

Gene SymbolEntrez IDGene Name
Tfap2a ENSMUSG00000021359.9 Tfap2a

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tfap2amm10_v2_chr13_-_40733768_40733836-0.191.2e-01Click!


Activity profile for motif Tfap2a.

activity profile for motif Tfap2a


Sorted Z-values histogram for motif Tfap2a

Sorted Z-values for motif Tfap2a



Network of associatons between targets according to the STRING database.



First level regulatory network of Tfap2a

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_+_21184103 9.891 ENSMUST00000115458.2
 Pde4a
phosphodiesterase 4A, cAMP specific
chr9_+_26733728 9.207 ENSMUST00000160899.1
ENSMUST00000161431.1
ENSMUST00000159799.1
 B3gat1


beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)


chr17_+_69969073 9.096 ENSMUST00000133983.1
 Dlgap1
discs, large (Drosophila) homolog-associated protein 1
chr5_-_146585239 9.004 ENSMUST00000036211.6
 Gpr12
G-protein coupled receptor 12
chr10_+_100015817 8.919 ENSMUST00000130190.1
ENSMUST00000020129.7
 Kitl

kit ligand

chr13_-_110280103 8.608 ENSMUST00000167824.1
 Rab3c
RAB3C, member RAS oncogene family
chr1_+_159737510 8.569 ENSMUST00000111669.3
 Tnr
tenascin R
chr10_-_86498836 7.802 ENSMUST00000120638.1
 Syn3
synapsin III
chr17_+_69969387 7.774 ENSMUST00000146730.1
 Dlgap1
discs, large (Drosophila) homolog-associated protein 1
chr17_+_69969217 7.771 ENSMUST00000060072.5
 Dlgap1
discs, large (Drosophila) homolog-associated protein 1
chr14_-_29721835 7.696 ENSMUST00000022567.7
 Cacna2d3
calcium channel, voltage-dependent, alpha2/delta subunit 3
chr13_+_54949388 7.588 ENSMUST00000026994.7
ENSMUST00000109994.2
 Unc5a

unc-5 homolog A (C. elegans)

chr5_+_117841839 7.532 ENSMUST00000142742.2
 Nos1
nitric oxide synthase 1, neuronal
chr9_+_109931774 6.365 ENSMUST00000169851.2
 Map4
microtubule-associated protein 4
chr4_-_20778527 6.293 ENSMUST00000119374.1
 Nkain3
Na+/K+ transporting ATPase interacting 3
chr10_+_81575306 6.129 ENSMUST00000146916.1
 Tle2
transducin-like enhancer of split 2, homolog of Drosophila E(spl)
chr12_+_40446050 5.989 ENSMUST00000037488.6
 Dock4
dedicator of cytokinesis 4
chr11_-_118909487 5.961 ENSMUST00000117731.1
ENSMUST00000106278.2
ENSMUST00000120061.1
ENSMUST00000017576.4
 Rbfox3



RNA binding protein, fox-1 homolog (C. elegans) 3



chr4_+_43381979 5.658 ENSMUST00000035645.5
ENSMUST00000144911.1
 Rusc2

RUN and SH3 domain containing 2

chr19_+_42255704 5.403 ENSMUST00000087123.5
 Golga7b
golgi autoantigen, golgin subfamily a, 7B

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 237 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.9 24.6 GO:0070842 aggresome assembly(GO:0070842)
1.0 20.2 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.5 15.2 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
1.9 13.3 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.5 12.3 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.1 9.7 GO:0002028 regulation of sodium ion transport(GO:0002028)
2.2 8.9 GO:0033024 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.0 8.8 GO:0007186 G-protein coupled receptor signaling pathway(GO:0007186)
0.1 8.7 GO:0099643 neurotransmitter secretion(GO:0007269) signal release from synapse(GO:0099643)
2.9 8.6 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.1 8.6 GO:0017157 regulation of exocytosis(GO:0017157)
0.9 7.6 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.5 7.4 GO:0050832 defense response to fungus(GO:0050832)
0.3 7.4 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
1.7 6.8 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
1.0 6.7 GO:0032811 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) negative regulation of epinephrine secretion(GO:0032811)
1.3 6.4 GO:0051012 microtubule sliding(GO:0051012) negative regulation of nonmotile primary cilium assembly(GO:1902856)
2.1 6.3 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.2 6.1 GO:2000785 regulation of autophagosome assembly(GO:2000785)
1.5 6.0 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 110 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 25.4 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 21.5 GO:0005794 Golgi apparatus(GO:0005794)
0.3 13.5 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 12.6 GO:0030426 growth cone(GO:0030426)
0.0 11.5 GO:0097708 cytoplasmic vesicle(GO:0031410) intracellular vesicle(GO:0097708)
0.3 11.4 GO:0032809 neuronal cell body membrane(GO:0032809)
0.5 10.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.2 10.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 8.8 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
2.9 8.6 GO:0072534 perineuronal net(GO:0072534)
0.1 8.5 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.7 7.5 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.1 7.2 GO:0008021 synaptic vesicle(GO:0008021)
1.3 6.7 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 6.6 GO:0005768 endosome(GO:0005768)
0.1 6.5 GO:0031225 anchored component of membrane(GO:0031225)
0.0 6.4 GO:0000139 Golgi membrane(GO:0000139)
0.2 6.2 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.2 6.0 GO:0032420 stereocilium(GO:0032420)
0.3 5.8 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 179 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 21.9 GO:0017137 Rab GTPase binding(GO:0017137)
3.4 20.2 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.3 11.9 GO:0030552 cAMP binding(GO:0030552)
0.2 10.6 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
1.0 10.4 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 9.4 GO:0030695 GTPase regulator activity(GO:0030695)
1.5 8.9 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.9 8.6 GO:0046625 sphingolipid binding(GO:0046625)
0.4 8.6 GO:0031489 myosin V binding(GO:0031489)
0.2 7.7 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
1.3 7.6 GO:0005042 netrin receptor activity(GO:0005042)
2.5 7.5 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.9 7.4 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
1.1 6.7 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.2 6.1 GO:0050681 androgen receptor binding(GO:0050681)
0.2 5.8 GO:0043849 Ras palmitoyltransferase activity(GO:0043849)
0.0 5.8 GO:0003714 transcription corepressor activity(GO:0003714)
0.7 5.7 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.2 5.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 5.6 GO:0005518 collagen binding(GO:0005518)