Motif ID: Tfap2d

Z-value: 0.887


Transcription factors associated with Tfap2d:

Gene SymbolEntrez IDGene Name
Tfap2d ENSMUSG00000042596.7 Tfap2d

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tfap2dmm10_v2_chr1_+_19103022_19103043-0.573.0e-07Click!


Activity profile for motif Tfap2d.

activity profile for motif Tfap2d


Sorted Z-values histogram for motif Tfap2d

Sorted Z-values for motif Tfap2d



Network of associatons between targets according to the STRING database.



First level regulatory network of Tfap2d

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_-_85688252 9.613 ENSMUST00000024947.7
ENSMUST00000163568.2
Six2

sine oculis-related homeobox 2

chr2_+_25180737 7.819 ENSMUST00000104999.2
Nrarp
Notch-regulated ankyrin repeat protein
chr2_+_119742306 7.741 ENSMUST00000028758.7
Itpka
inositol 1,4,5-trisphosphate 3-kinase A
chr18_+_82910863 6.795 ENSMUST00000171238.1
Zfp516
zinc finger protein 516
chr5_-_24527276 6.659 ENSMUST00000088311.4
Gbx1
gastrulation brain homeobox 1
chr11_-_32222233 6.615 ENSMUST00000150381.1
ENSMUST00000144902.1
ENSMUST00000020524.8
Rhbdf1


rhomboid family 1 (Drosophila)


chr4_+_152008803 6.598 ENSMUST00000097773.3
Klhl21
kelch-like 21
chr19_+_42147373 6.456 ENSMUST00000061111.9
Marveld1
MARVEL (membrane-associating) domain containing 1
chr2_+_26586607 6.312 ENSMUST00000174211.1
ENSMUST00000145575.2
ENSMUST00000173920.1
Egfl7


EGF-like domain 7


chr4_+_46450892 5.939 ENSMUST00000102926.4
Anp32b
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr4_-_106464167 5.623 ENSMUST00000049507.5
Pcsk9
proprotein convertase subtilisin/kexin type 9
chr7_+_65862029 5.400 ENSMUST00000055576.5
ENSMUST00000098391.4
Pcsk6

proprotein convertase subtilisin/kexin type 6

chr4_+_114406717 5.217 ENSMUST00000094894.3
Trabd2b
TraB domain containing 2B
chr12_-_80112998 5.114 ENSMUST00000165114.1
ENSMUST00000021552.1
Zfp36l1

zinc finger protein 36, C3H type-like 1

chr19_+_38481057 4.974 ENSMUST00000182481.1
Plce1
phospholipase C, epsilon 1
chr3_+_107595031 4.941 ENSMUST00000014747.1
Alx3
aristaless-like homeobox 3
chr18_-_80986578 4.929 ENSMUST00000057950.7
Sall3
sal-like 3 (Drosophila)
chr12_+_113098199 4.596 ENSMUST00000009099.6
ENSMUST00000109723.1
ENSMUST00000109726.1
ENSMUST00000109727.2
ENSMUST00000069690.4
Mta1




metastasis associated 1




chr6_-_82774448 4.588 ENSMUST00000000642.4
Hk2
hexokinase 2
chr11_+_120949053 4.562 ENSMUST00000154187.1
ENSMUST00000100130.3
ENSMUST00000129473.1
ENSMUST00000168579.1
Slc16a3



solute carrier family 16 (monocarboxylic acid transporters), member 3




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 161 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 15.0 GO:0035136 forelimb morphogenesis(GO:0035136)
2.4 9.6 GO:0097168 condensed mesenchymal cell proliferation(GO:0072137) mesenchymal stem cell proliferation(GO:0097168)
1.8 8.9 GO:0006447 regulation of translational initiation by iron(GO:0006447) positive regulation of translational initiation by iron(GO:0045994)
0.8 8.4 GO:0006020 inositol metabolic process(GO:0006020)
0.2 8.0 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.7 7.8 GO:0014807 regulation of somitogenesis(GO:0014807)
0.6 7.4 GO:0044458 motile cilium assembly(GO:0044458)
0.3 6.8 GO:0050873 brown fat cell differentiation(GO:0050873)
1.7 6.7 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.2 6.6 GO:0034629 cellular protein complex localization(GO:0034629)
1.1 6.5 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.5 6.0 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
1.9 5.8 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.5 5.6 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
1.8 5.4 GO:0007354 zygotic determination of anterior/posterior axis, embryo(GO:0007354)
0.7 5.2 GO:0018158 protein oxidation(GO:0018158)
0.0 5.2 GO:0048864 stem cell development(GO:0048864)
0.4 5.1 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.1 5.0 GO:0032835 glomerulus development(GO:0032835)
1.2 4.7 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 79 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 10.4 GO:0005739 mitochondrion(GO:0005739)
0.0 10.1 GO:0031012 extracellular matrix(GO:0031012)
0.0 9.7 GO:0005783 endoplasmic reticulum(GO:0005783)
0.1 9.3 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.3 8.6 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
2.7 8.0 GO:0005595 collagen type XII trimer(GO:0005595) anchoring collagen complex(GO:0030934)
0.1 8.0 GO:0005844 polysome(GO:0005844)
0.0 7.8 GO:0005667 transcription factor complex(GO:0005667)
0.1 7.6 GO:0036126 sperm flagellum(GO:0036126)
0.0 6.7 GO:0016604 nuclear body(GO:0016604)
0.9 6.6 GO:0005827 polar microtubule(GO:0005827)
0.4 6.5 GO:0042555 MCM complex(GO:0042555)
0.0 6.1 GO:0015629 actin cytoskeleton(GO:0015629)
1.9 5.6 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.1 5.0 GO:0016459 myosin complex(GO:0016459)
0.0 4.7 GO:0005681 spliceosomal complex(GO:0005681)
0.0 4.7 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 4.6 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 4.5 GO:0005923 bicellular tight junction(GO:0005923)
0.1 3.9 GO:0030027 lamellipodium(GO:0030027)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 120 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 25.9 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 22.6 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.1 11.8 GO:0033613 activating transcription factor binding(GO:0033613)
0.4 9.5 GO:0008266 poly(U) RNA binding(GO:0008266)
1.5 8.9 GO:0070644 vitamin D response element binding(GO:0070644)
0.3 8.9 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 8.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.3 8.0 GO:0005112 Notch binding(GO:0005112)
1.6 7.8 GO:0032027 myosin light chain binding(GO:0032027)
1.1 7.5 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1 6.4 GO:0005179 hormone activity(GO:0005179)
0.2 6.1 GO:0005109 frizzled binding(GO:0005109)
0.1 6.0 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
1.9 5.6 GO:0034190 very-low-density lipoprotein particle binding(GO:0034189) apolipoprotein receptor binding(GO:0034190)
0.5 5.6 GO:0001047 core promoter binding(GO:0001047)
0.6 5.4 GO:0048406 nerve growth factor binding(GO:0048406)
0.2 5.4 GO:0017091 AU-rich element binding(GO:0017091)
0.3 5.0 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.3 4.9 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.3 4.7 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)