Motif ID: Tgif2_Tgif2lx1_Tgif2lx2
Z-value: 0.846
Transcription factors associated with Tgif2_Tgif2lx1_Tgif2lx2:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Tgif2 | ENSMUSG00000062175.7 | Tgif2 |
Tgif2lx1 | ENSMUSG00000061283.4 | Tgif2lx1 |
Tgif2lx2 | ENSMUSG00000063242.6 | Tgif2lx2 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Tgif2 | mm10_v2_chr2_+_156840966_156841017 | -0.07 | 5.5e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.4 | 4.1 | GO:0007621 | negative regulation of female receptivity(GO:0007621) |
0.8 | 2.5 | GO:0043201 | response to leucine(GO:0043201) cellular response to leucine(GO:0071233) |
0.7 | 2.1 | GO:0003195 | tricuspid valve development(GO:0003175) tricuspid valve morphogenesis(GO:0003186) tricuspid valve formation(GO:0003195) right ventricular cardiac muscle tissue morphogenesis(GO:0003221) |
0.6 | 9.8 | GO:0050901 | leukocyte tethering or rolling(GO:0050901) |
0.4 | 1.2 | GO:2001187 | positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187) |
0.4 | 1.1 | GO:0010751 | regulation of arginine metabolic process(GO:0000821) negative regulation of nitric oxide mediated signal transduction(GO:0010751) negative regulation of cellular amino acid metabolic process(GO:0045763) |
0.4 | 3.0 | GO:0033564 | anterior/posterior axon guidance(GO:0033564) |
0.3 | 3.4 | GO:0007379 | segment specification(GO:0007379) |
0.3 | 1.0 | GO:0045204 | MAPK export from nucleus(GO:0045204) |
0.3 | 7.4 | GO:0001504 | neurotransmitter uptake(GO:0001504) |
0.3 | 1.9 | GO:1902897 | regulation of postsynaptic density protein 95 clustering(GO:1902897) |
0.3 | 2.2 | GO:0002591 | antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489) positive regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002591) |
0.3 | 7.4 | GO:0007617 | mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705) |
0.3 | 3.0 | GO:0070886 | positive regulation of calcineurin-NFAT signaling cascade(GO:0070886) |
0.3 | 2.9 | GO:1901621 | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621) |
0.2 | 5.5 | GO:0048268 | clathrin coat assembly(GO:0048268) |
0.2 | 0.7 | GO:0006030 | chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032) |
0.2 | 11.7 | GO:0030901 | midbrain development(GO:0030901) |
0.2 | 1.0 | GO:0032911 | nerve growth factor production(GO:0032902) negative regulation of transforming growth factor beta1 production(GO:0032911) |
0.2 | 2.0 | GO:0051103 | DNA ligation involved in DNA repair(GO:0051103) |
0.2 | 1.4 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
0.2 | 0.5 | GO:0021852 | pyramidal neuron migration(GO:0021852) |
0.2 | 0.5 | GO:0009405 | pathogenesis(GO:0009405) |
0.2 | 0.3 | GO:0042713 | sperm ejaculation(GO:0042713) |
0.2 | 1.4 | GO:0046459 | short-chain fatty acid metabolic process(GO:0046459) |
0.1 | 2.4 | GO:2001014 | regulation of skeletal muscle cell differentiation(GO:2001014) |
0.1 | 0.3 | GO:0071873 | response to norepinephrine(GO:0071873) |
0.1 | 0.8 | GO:0071955 | recycling endosome to Golgi transport(GO:0071955) |
0.1 | 0.7 | GO:0070474 | positive regulation of uterine smooth muscle contraction(GO:0070474) |
0.1 | 0.3 | GO:0048239 | negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695) |
0.1 | 0.9 | GO:0018230 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
0.1 | 0.8 | GO:0042523 | positive regulation of tyrosine phosphorylation of Stat5 protein(GO:0042523) |
0.1 | 1.0 | GO:0060081 | membrane hyperpolarization(GO:0060081) |
0.1 | 0.5 | GO:0002317 | plasma cell differentiation(GO:0002317) |
0.1 | 1.4 | GO:0010758 | regulation of macrophage chemotaxis(GO:0010758) |
0.1 | 0.3 | GO:0042796 | snRNA transcription from RNA polymerase III promoter(GO:0042796) |
0.1 | 0.7 | GO:0060501 | positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) |
0.1 | 0.4 | GO:0042701 | progesterone secretion(GO:0042701) |
0.1 | 1.3 | GO:2000251 | positive regulation of actin cytoskeleton reorganization(GO:2000251) |
0.1 | 1.0 | GO:0007096 | regulation of exit from mitosis(GO:0007096) |
0.1 | 0.4 | GO:2000210 | positive regulation of anoikis(GO:2000210) |
0.1 | 2.1 | GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I(GO:0002474) |
0.1 | 2.6 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
0.1 | 0.3 | GO:0021905 | pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) positive regulation of cell fate specification(GO:0042660) |
0.1 | 0.2 | GO:1903061 | establishment of protein localization to endoplasmic reticulum membrane(GO:0097051) regulation of protein lipidation(GO:1903059) positive regulation of protein lipidation(GO:1903061) |
0.0 | 1.2 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
0.0 | 1.9 | GO:0006376 | mRNA splice site selection(GO:0006376) |
0.0 | 0.3 | GO:0005981 | regulation of glycogen catabolic process(GO:0005981) |
0.0 | 1.0 | GO:0070584 | mitochondrion morphogenesis(GO:0070584) |
0.0 | 1.2 | GO:0071480 | cellular response to gamma radiation(GO:0071480) |
0.0 | 0.4 | GO:0070995 | NADPH oxidation(GO:0070995) |
0.0 | 0.4 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
0.0 | 0.3 | GO:0033169 | histone H3-K9 demethylation(GO:0033169) |
0.0 | 0.8 | GO:0003333 | amino acid transmembrane transport(GO:0003333) |
0.0 | 0.2 | GO:0090244 | Wnt signaling pathway involved in somitogenesis(GO:0090244) |
0.0 | 0.2 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
0.0 | 0.1 | GO:1990253 | cellular response to leucine starvation(GO:1990253) |
0.0 | 0.2 | GO:0048246 | macrophage chemotaxis(GO:0048246) |
0.0 | 3.4 | GO:0002250 | adaptive immune response(GO:0002250) |
0.0 | 1.1 | GO:0006888 | ER to Golgi vesicle-mediated transport(GO:0006888) |
0.0 | 0.5 | GO:0006198 | cAMP catabolic process(GO:0006198) |
0.0 | 1.1 | GO:0051209 | release of sequestered calcium ion into cytosol(GO:0051209) negative regulation of sequestering of calcium ion(GO:0051283) |
0.0 | 1.4 | GO:0008277 | regulation of G-protein coupled receptor protein signaling pathway(GO:0008277) |
0.0 | 0.5 | GO:0007099 | centriole replication(GO:0007099) |
0.0 | 0.0 | GO:0051902 | negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180) |
0.0 | 0.6 | GO:0007632 | visual behavior(GO:0007632) |
0.0 | 0.3 | GO:0000470 | maturation of LSU-rRNA(GO:0000470) |
0.0 | 0.2 | GO:0050848 | regulation of calcium-mediated signaling(GO:0050848) |
0.0 | 0.8 | GO:0042475 | odontogenesis of dentin-containing tooth(GO:0042475) |
0.0 | 0.2 | GO:0015693 | magnesium ion transport(GO:0015693) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 2.2 | GO:0030121 | AP-1 adaptor complex(GO:0030121) |
0.3 | 2.0 | GO:0043564 | Ku70:Ku80 complex(GO:0043564) |
0.2 | 2.9 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
0.2 | 1.0 | GO:0097513 | myosin II filament(GO:0097513) |
0.2 | 5.4 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
0.1 | 6.4 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
0.1 | 1.2 | GO:0000124 | SAGA complex(GO:0000124) |
0.1 | 3.8 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
0.1 | 0.5 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
0.1 | 0.9 | GO:0030312 | external encapsulating structure(GO:0030312) |
0.1 | 1.0 | GO:0012510 | trans-Golgi network transport vesicle membrane(GO:0012510) |
0.1 | 3.4 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
0.1 | 1.4 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
0.1 | 1.2 | GO:0042101 | T cell receptor complex(GO:0042101) |
0.1 | 1.1 | GO:0097228 | sperm principal piece(GO:0097228) |
0.1 | 0.5 | GO:0098536 | deuterosome(GO:0098536) |
0.0 | 0.6 | GO:0001527 | microfibril(GO:0001527) |
0.0 | 0.4 | GO:0042599 | lamellar body(GO:0042599) |
0.0 | 0.3 | GO:0042587 | glycogen granule(GO:0042587) |
0.0 | 0.3 | GO:0070545 | PeBoW complex(GO:0070545) |
0.0 | 2.2 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
0.0 | 0.4 | GO:0030061 | mitochondrial crista(GO:0030061) |
0.0 | 0.3 | GO:0000783 | telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783) |
0.0 | 10.8 | GO:0005667 | transcription factor complex(GO:0005667) |
0.0 | 1.1 | GO:0030286 | dynein complex(GO:0030286) |
0.0 | 2.7 | GO:0055037 | recycling endosome(GO:0055037) |
0.0 | 1.9 | GO:0043198 | dendritic shaft(GO:0043198) |
0.0 | 0.1 | GO:0071014 | post-mRNA release spliceosomal complex(GO:0071014) |
0.0 | 0.2 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
0.0 | 0.7 | GO:0005871 | kinesin complex(GO:0005871) |
0.0 | 10.4 | GO:0005773 | vacuole(GO:0005773) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.4 | 4.1 | GO:0031752 | D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752) |
0.9 | 5.5 | GO:0032051 | clathrin light chain binding(GO:0032051) |
0.5 | 3.0 | GO:0005042 | netrin receptor activity(GO:0005042) |
0.5 | 2.9 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
0.4 | 2.2 | GO:0015440 | peptide-transporting ATPase activity(GO:0015440) |
0.4 | 1.3 | GO:0010698 | acetyltransferase activator activity(GO:0010698) |
0.4 | 2.5 | GO:0070728 | leucine binding(GO:0070728) |
0.4 | 7.4 | GO:0005313 | L-glutamate transmembrane transporter activity(GO:0005313) |
0.3 | 1.1 | GO:0030292 | protein tyrosine kinase inhibitor activity(GO:0030292) |
0.2 | 0.7 | GO:0004568 | chitinase activity(GO:0004568) |
0.2 | 1.2 | GO:0015125 | virus receptor activity(GO:0001618) bile acid transmembrane transporter activity(GO:0015125) |
0.2 | 0.8 | GO:0042610 | CD8 receptor binding(GO:0042610) |
0.1 | 1.0 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
0.1 | 1.4 | GO:0004176 | ATP-dependent peptidase activity(GO:0004176) |
0.1 | 2.6 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
0.1 | 1.2 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
0.1 | 7.4 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
0.1 | 1.0 | GO:0048406 | nerve growth factor binding(GO:0048406) |
0.1 | 2.1 | GO:0042605 | peptide antigen binding(GO:0042605) |
0.1 | 1.1 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
0.1 | 1.4 | GO:0052890 | oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor(GO:0052890) |
0.1 | 1.4 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
0.1 | 1.0 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
0.1 | 0.5 | GO:0015643 | toxic substance binding(GO:0015643) |
0.1 | 0.2 | GO:0060072 | large conductance calcium-activated potassium channel activity(GO:0060072) |
0.1 | 1.1 | GO:0008188 | neuropeptide receptor activity(GO:0008188) |
0.0 | 0.4 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
0.0 | 0.4 | GO:0008395 | steroid hydroxylase activity(GO:0008395) |
0.0 | 0.8 | GO:0019706 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) |
0.0 | 0.3 | GO:0098505 | G-rich strand telomeric DNA binding(GO:0098505) |
0.0 | 0.3 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
0.0 | 0.4 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
0.0 | 5.5 | GO:0003714 | transcription corepressor activity(GO:0003714) |
0.0 | 0.3 | GO:0003680 | AT DNA binding(GO:0003680) |
0.0 | 0.2 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
0.0 | 14.4 | GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) |
0.0 | 1.5 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
0.0 | 0.3 | GO:0005225 | volume-sensitive anion channel activity(GO:0005225) |
0.0 | 1.9 | GO:0032947 | protein complex scaffold(GO:0032947) |
0.0 | 1.2 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
0.0 | 1.9 | GO:0030165 | PDZ domain binding(GO:0030165) |
0.0 | 0.0 | GO:0015143 | urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702) |
0.0 | 1.4 | GO:0003774 | motor activity(GO:0003774) |
0.0 | 0.2 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
0.0 | 0.8 | GO:0015297 | antiporter activity(GO:0015297) |
0.0 | 2.2 | GO:0003729 | mRNA binding(GO:0003729) |