Motif ID: Thra

Z-value: 0.623


Transcription factors associated with Thra:

Gene SymbolEntrez IDGene Name
Thra ENSMUSG00000058756.7 Thra

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Thramm10_v2_chr11_+_98741805_98741816-0.824.7e-18Click!


Activity profile for motif Thra.

activity profile for motif Thra


Sorted Z-values histogram for motif Thra

Sorted Z-values for motif Thra



Network of associatons between targets according to the STRING database.



First level regulatory network of Thra

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_44300876 8.571 ENSMUST00000045607.5
 Melk
maternal embryonic leucine zipper kinase
chr1_+_84839833 8.187 ENSMUST00000097672.3
 Fbxo36
F-box protein 36
chr18_+_57142782 7.131 ENSMUST00000139892.1
 Megf10
multiple EGF-like-domains 10
chr11_+_69965396 5.922 ENSMUST00000018713.6
 Cldn7
claudin 7
chr17_+_85620816 5.214 ENSMUST00000175898.2
 Six3
sine oculis-related homeobox 3
chr14_-_118052235 5.166 ENSMUST00000022725.2
 Dct
dopachrome tautomerase
chr4_-_137766474 4.967 ENSMUST00000139951.1
 Alpl
alkaline phosphatase, liver/bone/kidney
chr6_+_113531675 4.624 ENSMUST00000036340.5
ENSMUST00000101051.2
 Fancd2

Fanconi anemia, complementation group D2

chr13_+_94875600 4.617 ENSMUST00000022195.10
 Otp
orthopedia homolog (Drosophila)
chr5_-_116422858 4.593 ENSMUST00000036991.4
 Hspb8
heat shock protein 8
chr7_-_141214080 3.856 ENSMUST00000026573.5
ENSMUST00000170841.1
 1600016N20Rik

RIKEN cDNA 1600016N20 gene

chr6_+_83137089 3.808 ENSMUST00000121093.1
ENSMUST00000087938.4
 Rtkn

rhotekin

chr12_+_79029150 3.731 ENSMUST00000039928.5
 Plekhh1
pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chrX_-_143827391 3.684 ENSMUST00000087316.5
 Capn6
calpain 6
chr5_+_110839973 3.684 ENSMUST00000066160.1
 Chek2
checkpoint kinase 2
chr12_+_112678803 3.677 ENSMUST00000174780.1
ENSMUST00000169593.1
ENSMUST00000173942.1
 Zbtb42


zinc finger and BTB domain containing 42


chr10_+_93641041 3.610 ENSMUST00000020204.4
 Ntn4
netrin 4
chr14_-_70207637 3.587 ENSMUST00000022682.5
 Sorbs3
sorbin and SH3 domain containing 3
chr10_-_88146867 3.471 ENSMUST00000164121.1
ENSMUST00000164803.1
ENSMUST00000168163.1
ENSMUST00000048518.9
 Parpbp



PARP1 binding protein



chr1_-_163994767 3.275 ENSMUST00000097493.3
ENSMUST00000045876.6
 BC055324

cDNA sequence BC055324


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 103 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 8.6 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631)
0.2 8.2 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
1.4 7.1 GO:0014719 skeletal muscle satellite cell activation(GO:0014719)
1.7 6.7 GO:0098763 mitotic cell cycle phase(GO:0098763)
0.4 5.9 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
1.7 5.2 GO:0097402 neuroblast migration(GO:0097402)
0.9 5.2 GO:0006570 tyrosine metabolic process(GO:0006570)
0.0 5.2 GO:0051028 mRNA transport(GO:0051028)
0.2 5.0 GO:0046677 response to antibiotic(GO:0046677)
0.7 4.6 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.3 4.6 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.4 4.3 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 3.7 GO:0001578 microtubule bundle formation(GO:0001578)
0.7 3.6 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 3.6 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.5 3.5 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.4 3.4 GO:0061436 establishment of skin barrier(GO:0061436)
0.0 3.4 GO:0060348 bone development(GO:0060348)
0.3 3.2 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.8 3.1 GO:0051295 establishment of meiotic spindle localization(GO:0051295)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 58 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 8.8 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.3 7.1 GO:0001891 phagocytic cup(GO:0001891)
0.0 5.9 GO:0000776 kinetochore(GO:0000776)
0.0 5.8 GO:0005925 focal adhesion(GO:0005925)
0.2 5.2 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.5 5.0 GO:0031080 nuclear pore outer ring(GO:0031080)
0.3 5.0 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 4.6 GO:0000793 condensed chromosome(GO:0000793)
0.2 4.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 3.9 GO:0005667 transcription factor complex(GO:0005667)
0.1 3.7 GO:0005876 spindle microtubule(GO:0005876)
0.0 3.7 GO:0016605 PML body(GO:0016605)
0.1 3.6 GO:0034707 chloride channel complex(GO:0034707)
0.0 3.5 GO:0005938 cell cortex(GO:0005938)
1.0 3.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.6 3.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 2.8 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 2.2 GO:0005581 collagen trimer(GO:0005581)
0.0 2.2 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 2.1 GO:0043034 costamere(GO:0043034)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 81 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 10.1 GO:0005198 structural molecule activity(GO:0005198)
0.2 8.0 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 6.3 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.4 5.2 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.3 5.2 GO:0001222 transcription corepressor binding(GO:0001222)
1.2 5.0 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.3 4.6 GO:0070182 DNA polymerase binding(GO:0070182)
0.4 4.3 GO:0015245 fatty acid transporter activity(GO:0015245)
0.1 4.3 GO:0032452 histone demethylase activity(GO:0032452)
0.5 3.8 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.2 3.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.5 3.6 GO:0043237 laminin-1 binding(GO:0043237)
0.2 3.6 GO:0017166 vinculin binding(GO:0017166)
0.1 3.6 GO:0005254 chloride channel activity(GO:0005254)
0.1 3.5 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.4 3.1 GO:0043495 protein anchor(GO:0043495)
0.2 3.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 2.9 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.3 2.6 GO:0050693 LBD domain binding(GO:0050693)
0.0 2.6 GO:0003924 GTPase activity(GO:0003924)