• All motifs sorted by activity significance
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• Mean activities
• All promoters sorted by FOV

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: Trp53

Z-value: 1.131

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr2_-_69206146	19.371	ENSMUST00000127243.1 ENSMUST00000149643.1 ENSMUST00000167875.2 ENSMUST00000005365.8	Spc25	SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr17_-_33890584	17.322	ENSMUST00000114361.2 ENSMUST00000173492.1	Kifc1	kinesin family member C1
chr15_-_98004695	17.153	ENSMUST00000023123.8	Col2a1	collagen, type II, alpha 1
chr15_-_98004634	16.714	ENSMUST00000131560.1 ENSMUST00000088355.5	Col2a1	collagen, type II, alpha 1
chr17_-_33890539	16.079	ENSMUST00000173386.1	Kifc1	kinesin family member C1
chr2_-_69206133	15.462	ENSMUST00000112320.1	Spc25	SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr8_-_22185758	13.123	ENSMUST00000046916.7	Ckap2	cytoskeleton associated protein 2
chr15_+_85859689	10.393	ENSMUST00000170629.1	Gtse1	G two S phase expressed protein 1
chr11_-_102925086	10.117	ENSMUST00000021311.9	Kif18b	kinesin family member 18B
chr1_+_6487231	9.758	ENSMUST00000140079.1 ENSMUST00000131494.1	St18	suppression of tumorigenicity 18
chr14_+_73237891	8.904	ENSMUST00000044405.6	Lpar6	lysophosphatidic acid receptor 6
chr8_+_94977101	8.879	ENSMUST00000179619.1	Gpr56	G protein-coupled receptor 56
chr1_-_79858627	8.686	ENSMUST00000027467.4	Serpine2	serine (or cysteine) peptidase inhibitor, clade E, member 2
chr10_+_56377300	8.258	ENSMUST00000068581.7	Gja1	gap junction protein, alpha 1
chr14_+_47001336	7.527	ENSMUST00000125113.1	Samd4	sterile alpha motif domain containing 4
chr5_-_30073554	7.341	ENSMUST00000026846.6	Tyms	thymidylate synthase
chr2_+_59612034	7.097	ENSMUST00000112568.1 ENSMUST00000037526.4	Tanc1	tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
chr3_-_75956888	7.050	ENSMUST00000038563.7 ENSMUST00000167078.1 ENSMUST00000117242.1	Golim4	golgi integral membrane protein 4
chr14_-_103843685	7.008	ENSMUST00000172237.1	Ednrb	endothelin receptor type B
chr5_-_116422858	6.963	ENSMUST00000036991.4	Hspb8	heat shock protein 8
chr10_+_93641041	6.897	ENSMUST00000020204.4	Ntn4	netrin 4
chr11_-_3527916	6.856	ENSMUST00000020718.4	Smtn	smoothelin
chr17_+_29090969	6.822	ENSMUST00000119901.1	Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)
chr9_+_72438534	6.551	ENSMUST00000034746.8	Mns1	meiosis-specific nuclear structural protein 1
chr9_-_106158109	6.403	ENSMUST00000159809.1 ENSMUST00000162562.1 ENSMUST00000036382.6 ENSMUST00000112543.2	Glyctk	glycerate kinase
chr9_+_72438519	6.240	ENSMUST00000184604.1	Mns1	meiosis-specific nuclear structural protein 1
chr9_+_66946057	5.898	ENSMUST00000040917.7 ENSMUST00000127896.1	Rps27l	ribosomal protein S27-like
chr17_+_26917091	5.835	ENSMUST00000078961.4	Kifc5b	kinesin family member C5B
chr14_-_54926784	5.581	ENSMUST00000022813.6	Efs	embryonal Fyn-associated substrate
chr13_+_113317084	5.339	ENSMUST00000136755.2	BC067074	cDNA sequence BC067074
chr2_+_72285637	5.174	ENSMUST00000090824.5 ENSMUST00000135469.1	Zak	sterile alpha motif and leucine zipper containing kinase AZK
chr14_+_13454010	5.162	ENSMUST00000112656.2	Synpr	synaptoporin
chrX_-_142306170	4.870	ENSMUST00000134825.2	Kcne1l	potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene
chr15_-_102350692	4.780	ENSMUST00000041208.7	Aaas	achalasia, adrenocortical insufficiency, alacrimia
chr10_-_81350389	4.750	ENSMUST00000020454.4 ENSMUST00000105324.2 ENSMUST00000154609.2 ENSMUST00000105323.1	Hmg20b	high mobility group 20B
chr4_-_135573623	4.711	ENSMUST00000105855.1	Grhl3	grainyhead-like 3 (Drosophila)
chr14_-_34374617	4.611	ENSMUST00000023826.4	Sncg	synuclein, gamma
chr2_-_155074447	4.606	ENSMUST00000137242.1 ENSMUST00000054607.9	Ahcy	S-adenosylhomocysteine hydrolase
chr9_-_100486788	4.519	ENSMUST00000098458.3	Il20rb	interleukin 20 receptor beta
chr1_+_82339049	4.516	ENSMUST00000140020.1	Rhbdd1	rhomboid domain containing 1
chr10_-_81350191	4.472	ENSMUST00000122993.1	Hmg20b	high mobility group 20B
chr9_+_107576915	4.457	ENSMUST00000112387.2 ENSMUST00000123005.1 ENSMUST00000010195.7 ENSMUST00000144392.1	Hyal1	hyaluronoglucosaminidase 1
chr7_+_75455534	4.267	ENSMUST00000147005.1 ENSMUST00000166315.1	Akap13	A kinase (PRKA) anchor protein 13
chr4_-_96591555	4.164	ENSMUST00000055693.8	Cyp2j9	cytochrome P450, family 2, subfamily j, polypeptide 9
chr10_-_81350305	4.048	ENSMUST00000167481.1	Hmg20b	high mobility group 20B
chr14_+_13453937	3.847	ENSMUST00000153954.1	Synpr	synaptoporin
chr10_+_94550852	3.394	ENSMUST00000148910.1 ENSMUST00000117460.1	Tmcc3	transmembrane and coiled coil domains 3
chr5_+_114707760	3.364	ENSMUST00000094441.4	Tchp	trichoplein, keratin filament binding
chr9_+_45138437	3.360	ENSMUST00000060125.5	Scn4b	sodium channel, type IV, beta
chr10_+_110745433	3.168	ENSMUST00000174857.1 ENSMUST00000073781.5 ENSMUST00000173471.1 ENSMUST00000173634.1	E2f7	E2F transcription factor 7
chr2_+_29889217	2.886	ENSMUST00000123335.1	Odf2	outer dense fiber of sperm tails 2
chr9_-_72985344	2.779	ENSMUST00000124565.2	Gm5918	predicted gene 5918
chr6_+_128438757	2.749	ENSMUST00000144745.1	Gm10069	predicted gene 10069
chr4_+_115057683	2.680	ENSMUST00000161601.1	Tal1	T cell acute lymphocytic leukemia 1
chr11_+_17211912	2.673	ENSMUST00000046955.6	Wdr92	WD repeat domain 92
chr4_-_43030440	2.657	ENSMUST00000135660.1	Stoml2	stomatin (Epb7.2)-like 2
chr9_+_38719024	2.586	ENSMUST00000129598.1	Vwa5a	von Willebrand factor A domain containing 5A
chr7_-_98309471	2.564	ENSMUST00000033020.7	Acer3	alkaline ceramidase 3
chr2_-_155592567	2.509	ENSMUST00000155347.1 ENSMUST00000130881.1 ENSMUST00000079691.6	Gss	glutathione synthetase
chr5_-_138272733	2.436	ENSMUST00000161665.1 ENSMUST00000100530.1	Gal3st4	galactose-3-O-sulfotransferase 4
chr4_+_132351768	2.409	ENSMUST00000172202.1	Gm17300	predicted gene, 17300
chr2_+_29890063	2.400	ENSMUST00000028128.6	Odf2	outer dense fiber of sperm tails 2
chr2_-_164857542	2.384	ENSMUST00000109316.1 ENSMUST00000156255.1 ENSMUST00000128110.1 ENSMUST00000109317.3	Pltp	phospholipid transfer protein
chr4_-_9643638	2.320	ENSMUST00000108333.1 ENSMUST00000108334.1 ENSMUST00000108335.1 ENSMUST00000152526.1 ENSMUST00000103004.3	Asph	aspartate-beta-hydroxylase
chr17_+_87282880	2.278	ENSMUST00000041110.5 ENSMUST00000125875.1	Ttc7	tetratricopeptide repeat domain 7
chr13_+_21754067	2.189	ENSMUST00000091709.2	Hist1h2bn	histone cluster 1, H2bn
chr7_+_130936172	2.150	ENSMUST00000006367.7	Htra1	HtrA serine peptidase 1
chr16_+_20651652	2.116	ENSMUST00000007212.8	Psmd2	proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
chr14_-_70653081	2.085	ENSMUST00000062629.4	Npm2	nucleophosmin/nucleoplasmin 2
chr12_+_59129720	2.055	ENSMUST00000175912.1 ENSMUST00000176892.1	Ctage5	CTAGE family, member 5
chr17_+_35821675	2.046	ENSMUST00000003635.6	Ier3	immediate early response 3
chr12_+_59129757	2.015	ENSMUST00000069430.8 ENSMUST00000177370.1	Ctage5	CTAGE family, member 5
chr16_-_59632520	1.994	ENSMUST00000118438.1	Arl6	ADP-ribosylation factor-like 6
chr4_+_115057410	1.978	ENSMUST00000136946.1	Tal1	T cell acute lymphocytic leukemia 1
chr11_-_17211504	1.910	ENSMUST00000020317.7	Pno1	partner of NOB1 homolog (S. cerevisiae)
chr6_-_38837224	1.892	ENSMUST00000160962.1	Hipk2	homeodomain interacting protein kinase 2
chr2_+_152962485	1.873	ENSMUST00000099197.2 ENSMUST00000103155.3	Ttll9	tubulin tyrosine ligase-like family, member 9
chr2_-_17731035	1.811	ENSMUST00000028080.5	Nebl	nebulette
chr14_+_74735641	1.785	ENSMUST00000177283.1	Esd	esterase D/formylglutathione hydrolase
chr15_+_83100281	1.777	ENSMUST00000167389.1 ENSMUST00000166427.1	Serhl	serine hydrolase-like
chr7_+_64392645	1.773	ENSMUST00000037205.8	Mcee	methylmalonyl CoA epimerase
chr5_-_138272786	1.728	ENSMUST00000161279.1 ENSMUST00000161647.1	Gal3st4	galactose-3-O-sulfotransferase 4
chr12_-_70231414	1.654	ENSMUST00000161083.1	Pygl	liver glycogen phosphorylase
chr9_-_114982739	1.584	ENSMUST00000053150.5	Gm9846	predicted gene 9846
chr17_-_24696147	1.549	ENSMUST00000046839.8	Gfer	growth factor, erv1 (S. cerevisiae)-like (augmenter of liver regeneration)
chr16_+_20717665	1.508	ENSMUST00000021405.7	Polr2h	polymerase (RNA) II (DNA directed) polypeptide H
chr18_+_61639542	1.500	ENSMUST00000183083.1 ENSMUST00000183087.1	Gm20748	predicted gene, 20748
chr4_+_116596672	1.482	ENSMUST00000051869.7	Ccdc17	coiled-coil domain containing 17
chr4_-_129641060	1.472	ENSMUST00000046425.9 ENSMUST00000133803.1	Txlna	taxilin alpha
chr4_-_129640959	1.447	ENSMUST00000132217.1 ENSMUST00000130017.1 ENSMUST00000154105.1	Txlna	taxilin alpha
chr5_+_34989473	1.396	ENSMUST00000114284.1 ENSMUST00000114285.1	Rgs12	regulator of G-protein signaling 12
chr9_-_108263706	1.342	ENSMUST00000171412.1	Dag1	dystroglycan 1
chr14_-_20496780	1.335	ENSMUST00000022353.3	Mss51	MSS51 mitochondrial translational activator
chr6_+_134981998	1.256	ENSMUST00000167323.1	Apold1	apolipoprotein L domain containing 1
chr3_-_28765364	1.220	ENSMUST00000094335.3	Gm6505	predicted pseudogene 6505
chr12_+_76255209	1.211	ENSMUST00000021443.5	Mthfd1	methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase
chr13_+_22035821	1.169	ENSMUST00000110455.2	Hist1h2bk	histone cluster 1, H2bk
chr3_-_132950043	1.156	ENSMUST00000117164.1 ENSMUST00000093971.4 ENSMUST00000042729.9 ENSMUST00000042744.9 ENSMUST00000117811.1	Npnt	nephronectin
chrX_-_38635066	1.120	ENSMUST00000058265.7	C1galt1c1	C1GALT1-specific chaperone 1
chr11_+_88204396	1.118	ENSMUST00000118784.1 ENSMUST00000139170.1 ENSMUST00000107915.3 ENSMUST00000144070.1	Mrps23	mitochondrial ribosomal protein S23
chr1_+_88103229	1.098	ENSMUST00000113135.3 ENSMUST00000113138.1	Ugt1a6a Ugt1a6b	UDP glucuronosyltransferase 1 family, polypeptide A6A UDP glucuronosyltransferase 1 family, polypeptide A6B
chrX_+_74254782	1.093	ENSMUST00000119197.1 ENSMUST00000088313.4	Emd	emerin
chr15_-_77927728	1.083	ENSMUST00000174468.1 ENSMUST00000174529.1 ENSMUST00000173631.1	Txn2	thioredoxin 2
chr15_+_83100201	1.048	ENSMUST00000078218.4	Serhl	serine hydrolase-like
chr1_+_161969179	1.030	ENSMUST00000111594.2 ENSMUST00000028021.6	Pigc	phosphatidylinositol glycan anchor biosynthesis, class C
chr10_+_80622677	0.969	ENSMUST00000079773.6	Csnk1g2	casein kinase 1, gamma 2
chr7_-_114927726	0.934	ENSMUST00000059737.2	Gm6816	predicted gene 6816
chr8_-_84893887	0.933	ENSMUST00000003907.7 ENSMUST00000182458.1 ENSMUST00000109745.1 ENSMUST00000142748.1	Gcdh	glutaryl-Coenzyme A dehydrogenase
chr4_-_83285141	0.892	ENSMUST00000150522.1	Ttc39b	tetratricopeptide repeat domain 39B
chr14_-_55944536	0.891	ENSMUST00000022834.6	Cma1	chymase 1, mast cell
chr1_-_191907527	0.861	ENSMUST00000069573.5	1700034H15Rik	RIKEN cDNA 1700034H15 gene
chr7_-_28962265	0.860	ENSMUST00000068045.7	Actn4	actinin alpha 4
chr17_+_32506446	0.808	ENSMUST00000165999.1	Cyp4f17	cytochrome P450, family 4, subfamily f, polypeptide 17
chr3_+_96172327	0.775	ENSMUST00000076372.4	Sf3b4	splicing factor 3b, subunit 4
chr9_-_26999491	0.749	ENSMUST00000060513.7 ENSMUST00000120367.1	Acad8	acyl-Coenzyme A dehydrogenase family, member 8
chr2_+_10372426	0.734	ENSMUST00000114864.2 ENSMUST00000116594.2 ENSMUST00000041105.6	Sfmbt2	Scm-like with four mbt domains 2
chr2_-_130664565	0.670	ENSMUST00000089559.4	Ddrgk1	DDRGK domain containing 1
chr11_+_87582201	0.646	ENSMUST00000133202.1	Sept4	septin 4
chr1_+_161969284	0.599	ENSMUST00000160881.1 ENSMUST00000159648.1	Pigc	phosphatidylinositol glycan anchor biosynthesis, class C
chr8_-_22694061	0.598	ENSMUST00000131767.1	Ikbkb	inhibitor of kappaB kinase beta
chr7_+_97332311	0.597	ENSMUST00000054107.5	Kctd21	potassium channel tetramerisation domain containing 21
chr11_-_93968293	0.542	ENSMUST00000170303.1	Gm20390	predicted gene 20390
chr3_+_79885930	0.498	ENSMUST00000029567.8	Fam198b	family with sequence similarity 198, member B
chr11_-_102469839	0.490	ENSMUST00000103086.3	Itga2b	integrin alpha 2b
chr7_-_28962223	0.444	ENSMUST00000127210.1	Actn4	actinin alpha 4
chr7_+_24884809	0.399	ENSMUST00000156372.1 ENSMUST00000124035.1	Rps19	ribosomal protein S19
chr7_-_64872993	0.371	ENSMUST00000094331.2	Ndnl2	necdin-like 2
chr11_+_52360824	0.368	ENSMUST00000102758.1	Vdac1	voltage-dependent anion channel 1
chr15_+_100154379	0.348	ENSMUST00000023768.6 ENSMUST00000108971.2	Dip2b	DIP2 disco-interacting protein 2 homolog B (Drosophila)
chr5_-_38502107	0.313	ENSMUST00000005238.6	Slc2a9	solute carrier family 2 (facilitated glucose transporter), member 9
chr9_-_21963568	0.309	ENSMUST00000006397.5	Epor	erythropoietin receptor
chr16_-_11909398	0.293	ENSMUST00000127972.1 ENSMUST00000121750.1 ENSMUST00000096272.4 ENSMUST00000073371.6	Cpped1	calcineurin-like phosphoesterase domain containing 1
chr19_-_47138280	0.260	ENSMUST00000140512.1 ENSMUST00000035822.1	Calhm2	calcium homeostasis modulator 2
chr9_-_70141484	0.251	ENSMUST00000034749.8	Fam81a	family with sequence similarity 81, member A
chr4_-_42084291	0.247	ENSMUST00000177937.1	Gm21968	predicted gene, 21968
chr2_+_129100995	0.187	ENSMUST00000103205.4 ENSMUST00000028874.7	Polr1b	polymerase (RNA) I polypeptide B
chr4_+_141213948	0.170	ENSMUST00000097813.2	Rsg1	REM2 and RAB-like small GTPase 1
chrX_-_37191160	0.160	ENSMUST00000016571.7	Ndufa1	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1
chr12_-_74316394	0.145	ENSMUST00000110441.1	Gm11042	predicted gene 11042
chr6_-_118562226	0.066	ENSMUST00000112830.1	Ankrd26	ankyrin repeat domain 26
chr9_+_61373219	0.027	ENSMUST00000162583.1 ENSMUST00000161993.1 ENSMUST00000160882.1 ENSMUST00000160724.1 ENSMUST00000162973.1 ENSMUST00000159050.1	Tle3	transducin-like enhancer of split 3, homolog of Drosophila E(spl)
chr5_+_34999046	0.023	ENSMUST00000114281.1	Rgs12	regulator of G-protein signaling 12
chr5_-_38480131	0.001	ENSMUST00000143758.1 ENSMUST00000067886.5	Slc2a9	solute carrier family 2 (facilitated glucose transporter), member 9

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
8.4	33.4	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
3.2	38.3	GO:0060272	embryonic skeletal joint morphogenesis(GO:0060272)
2.9	8.7	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
2.8	8.3	GO:0003104	positive regulation of glomerular filtration(GO:0003104) cell communication by chemical coupling(GO:0010643)
2.4	7.3	GO:0046078	deoxyribonucleoside monophosphate biosynthetic process(GO:0009157) pyrimidine deoxyribonucleoside monophosphate biosynthetic process(GO:0009177) dUMP metabolic process(GO:0046078)
2.3	7.0	GO:0014826	vein smooth muscle contraction(GO:0014826)
1.6	4.7	GO:0060217	hemangioblast cell differentiation(GO:0060217)
1.5	4.5	GO:0002765	immune response-inhibiting signal transduction(GO:0002765)
1.5	4.5	GO:1904211	membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
1.4	6.9	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
1.2	4.9	GO:0099624	regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372) atrial cardiac muscle cell membrane repolarization(GO:0099624)
1.1	3.2	GO:0032877	positive regulation of DNA endoreduplication(GO:0032877)
0.9	2.7	GO:1990046	positive regulation of mitochondrial DNA replication(GO:0090297) regulation of cardiolipin metabolic process(GO:1900208) positive regulation of cardiolipin metabolic process(GO:1900210) stress-induced mitochondrial fusion(GO:1990046)
0.9	13.3	GO:0033234	negative regulation of protein sumoylation(GO:0033234)
0.9	6.8	GO:0071493	cellular response to UV-B(GO:0071493)
0.8	12.8	GO:0070986	left/right axis specification(GO:0070986)
0.8	2.3	GO:0042264	peptidyl-aspartic acid hydroxylation(GO:0042264)
0.7	2.1	GO:0060718	chorionic trophoblast cell differentiation(GO:0060718)
0.7	4.3	GO:0071883	activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.7	3.4	GO:1902018	negative regulation of cilium assembly(GO:1902018)
0.6	2.4	GO:0042360	vitamin E metabolic process(GO:0042360)
0.6	4.6	GO:0033353	S-adenosylmethionine cycle(GO:0033353)
0.5	4.7	GO:0061436	establishment of skin barrier(GO:0061436)
0.5	2.0	GO:0046909	intermembrane transport(GO:0046909)
0.4	1.8	GO:0046294	formaldehyde catabolic process(GO:0046294)
0.4	1.3	GO:1902396	protein localization to bicellular tight junction(GO:1902396)
0.4	1.7	GO:0046391	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.4	7.1	GO:0097062	dendritic spine maintenance(GO:0097062)
0.4	34.8	GO:0007052	mitotic spindle organization(GO:0007052)
0.4	1.1	GO:0009812	flavonoid metabolic process(GO:0009812) flavonoid biosynthetic process(GO:0009813) flavonoid glucuronidation(GO:0052696)
0.4	23.2	GO:0007019	microtubule depolymerization(GO:0007019)
0.3	2.0	GO:1901029	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.3	3.4	GO:0099623	regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307) regulation of cardiac muscle cell membrane repolarization(GO:0099623) ventricular cardiac muscle cell membrane repolarization(GO:0099625)
0.3	1.3	GO:0016340	calcium-dependent cell-matrix adhesion(GO:0016340)
0.3	1.2	GO:0006547	histidine metabolic process(GO:0006547)
0.3	2.6	GO:0034312	diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520)
0.2	4.2	GO:0019369	arachidonic acid metabolic process(GO:0019369)
0.2	5.3	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.2	1.9	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.2	2.1	GO:0007096	regulation of exit from mitosis(GO:0007096)
0.2	1.1	GO:0016266	O-glycan processing(GO:0016266)
0.2	1.5	GO:1903204	negative regulation of oxidative stress-induced neuron death(GO:1903204)
0.2	1.2	GO:0010694	positive regulation of alkaline phosphatase activity(GO:0010694)
0.2	4.6	GO:0014046	dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.2	2.5	GO:0046686	response to cadmium ion(GO:0046686)
0.2	2.7	GO:0035337	fatty-acyl-CoA metabolic process(GO:0035337)
0.2	1.1	GO:0000103	sulfate assimilation(GO:0000103)
0.1	0.7	GO:0038032	termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.1	5.2	GO:0000186	activation of MAPKK activity(GO:0000186)
0.1	0.6	GO:1903347	negative regulation of bicellular tight junction assembly(GO:1903347)
0.1	5.3	GO:1902017	regulation of cilium assembly(GO:1902017)
0.1	0.7	GO:1990564	protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1	0.6	GO:0030382	sperm mitochondrion organization(GO:0030382)
0.1	1.1	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.1	2.3	GO:0006879	cellular iron ion homeostasis(GO:0006879)
0.1	6.7	GO:0045727	positive regulation of translation(GO:0045727)
0.0	0.6	GO:0002227	innate immune response in mucosa(GO:0002227)
0.0	0.7	GO:0009083	branched-chain amino acid catabolic process(GO:0009083)
0.0	0.3	GO:0061032	visceral serous pericardium development(GO:0061032)
0.0	4.8	GO:0009566	fertilization(GO:0009566)
0.0	0.8	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0	1.6	GO:0006506	GPI anchor biosynthetic process(GO:0006506)
0.0	0.3	GO:0046415	urate metabolic process(GO:0046415)
0.0	0.2	GO:0007000	nucleolus organization(GO:0007000)
0.0	0.4	GO:0006851	mitochondrial calcium ion transport(GO:0006851)
0.0	2.9	GO:0098780	mitophagy in response to mitochondrial depolarization(GO:0098779) response to mitochondrial depolarisation(GO:0098780)
0.0	0.9	GO:0032611	interleukin-1 beta production(GO:0032611)
0.0	4.2	GO:0009101	glycoprotein biosynthetic process(GO:0009101)
0.0	0.5	GO:0006220	pyrimidine nucleotide metabolic process(GO:0006220)
0.0	2.6	GO:0007018	microtubule-based movement(GO:0007018)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.8	34.8	GO:0031262	Ndc80 complex(GO:0031262)
3.3	13.3	GO:0002111	BRCA2-BRAF35 complex(GO:0002111)
2.6	33.9	GO:0098643	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
2.3	6.8	GO:0070557	PCNA-p21 complex(GO:0070557)
2.1	33.4	GO:0031616	spindle pole centrosome(GO:0031616)
1.7	10.1	GO:0000235	astral microtubule(GO:0000235)
1.6	4.7	GO:0033193	Lsd1/2 complex(GO:0033193)
0.9	9.0	GO:0030285	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.8	8.7	GO:0031091	platelet alpha granule(GO:0031091) extrinsic component of external side of plasma membrane(GO:0031232)
0.8	8.3	GO:0005916	fascia adherens(GO:0005916)
0.6	3.4	GO:0045179	apical cortex(GO:0045179)
0.5	2.3	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.4	4.5	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.4	23.5	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.2	1.2	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.2	1.3	GO:0016011	dystroglycan complex(GO:0016011)
0.2	3.4	GO:0034706	voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.2	2.7	GO:0042101	T cell receptor complex(GO:0042101)
0.2	2.5	GO:0097539	ciliary transition fiber(GO:0097539)
0.2	10.4	GO:0005882	intermediate filament(GO:0005882)
0.2	2.1	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540) cytosolic proteasome complex(GO:0031597)
0.2	0.6	GO:0097227	sperm annulus(GO:0097227)
0.1	1.1	GO:0005652	nuclear lamina(GO:0005652)
0.1	1.6	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1	5.3	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.1	1.7	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.1	5.8	GO:0005871	kinesin complex(GO:0005871)
0.1	1.3	GO:0031143	pseudopodium(GO:0031143)
0.1	6.7	GO:0005604	basement membrane(GO:0005604)
0.1	10.3	GO:0043679	axon terminus(GO:0043679)
0.1	4.7	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
0.0	2.6	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.4	GO:0030915	Smc5-Smc6 complex(GO:0030915)
0.0	0.6	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	8.0	GO:0031965	nuclear membrane(GO:0031965)
0.0	0.4	GO:0046930	pore complex(GO:0046930)
0.0	0.7	GO:0097440	apical dendrite(GO:0097440)
0.0	0.5	GO:0008305	integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0	3.3	GO:0005884	actin filament(GO:0005884)
0.0	0.7	GO:0016235	aggresome(GO:0016235)
0.0	8.1	GO:0019866	mitochondrial inner membrane(GO:0005743) organelle inner membrane(GO:0019866)
0.0	1.9	GO:0090575	RNA polymerase II transcription factor complex(GO:0090575)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
8.4	33.4	GO:0008569	ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
2.3	7.0	GO:0004962	endothelin receptor activity(GO:0004962)
2.3	33.9	GO:0048407	platelet-derived growth factor binding(GO:0048407)
1.7	8.3	GO:0071253	connexin binding(GO:0071253)
1.5	4.5	GO:0050501	hyaluronan synthase activity(GO:0050501)
1.1	4.5	GO:0042015	interleukin-20 binding(GO:0042015)
1.0	6.9	GO:0043237	laminin-1 binding(GO:0043237)
1.0	5.9	GO:0008494	translation activator activity(GO:0008494)
1.0	4.9	GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.9	2.7	GO:1901611	phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.8	4.2	GO:0008392	arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.7	10.1	GO:1990939	ATP-dependent microtubule motor activity(GO:1990939)
0.7	4.6	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.6	13.3	GO:0000400	four-way junction DNA binding(GO:0000400)
0.6	1.8	GO:0018738	S-formylglutathione hydrolase activity(GO:0018738)
0.6	1.7	GO:0032052	bile acid binding(GO:0032052)
0.5	6.8	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.5	3.4	GO:0086006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.4	7.3	GO:0005542	folic acid binding(GO:0005542)
0.4	2.6	GO:0017040	ceramidase activity(GO:0017040)
0.4	1.2	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.4	1.5	GO:0016971	flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.3	7.5	GO:0030371	translation repressor activity(GO:0030371)
0.3	4.3	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.2	1.9	GO:0046790	virion binding(GO:0046790)
0.2	0.6	GO:0008384	IkappaB kinase activity(GO:0008384)
0.2	8.7	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.2	1.6	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.2	2.5	GO:0016594	glycine binding(GO:0016594)
0.2	1.5	GO:0001055	RNA polymerase II activity(GO:0001055)
0.1	5.2	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.1	4.6	GO:0043014	alpha-tubulin binding(GO:0043014)
0.1	0.7	GO:0034916	4-methyloctanoyl-CoA dehydrogenase activity(GO:0034580) naphthyl-2-methyl-succinyl-CoA dehydrogenase activity(GO:0034845) 2-methylhexanoyl-CoA dehydrogenase activity(GO:0034916) propionyl-CoA dehydrogenase activity(GO:0043820) thiol-driven fumarate reductase activity(GO:0043830) coenzyme F420-dependent 2,4,6-trinitrophenol reductase activity(GO:0052758) coenzyme F420-dependent 2,4,6-trinitrophenol hydride reductase activity(GO:0052759) coenzyme F420-dependent 2,4-dinitrophenol reductase activity(GO:0052760)
0.1	0.5	GO:0070051	fibrinogen binding(GO:0070051)
0.1	1.3	GO:0051393	alpha-actinin binding(GO:0051393)
0.1	5.8	GO:0003777	microtubule motor activity(GO:0003777)
0.1	1.1	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1	4.2	GO:0050694	galactose 3-O-sulfotransferase activity(GO:0050694)
0.1	1.1	GO:0048531	beta-1,3-galactosyltransferase activity(GO:0048531)
0.1	0.3	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1	4.7	GO:0070888	E-box binding(GO:0070888)
0.1	2.1	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.1	5.6	GO:0017124	SH3 domain binding(GO:0017124)
0.1	1.8	GO:0016854	racemase and epimerase activity(GO:0016854)
0.1	5.1	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.1	5.3	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.1	0.9	GO:0052890	acyl-CoA dehydrogenase activity(GO:0003995) oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor(GO:0052890)
0.1	6.0	GO:0031490	chromatin DNA binding(GO:0031490)
0.1	0.4	GO:0015288	porin activity(GO:0015288)
0.0	2.3	GO:0016706	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0	2.9	GO:0019905	syntaxin binding(GO:0019905)
0.0	0.5	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
0.0	2.7	GO:0043130	ubiquitin binding(GO:0043130)
0.0	0.7	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	3.2	GO:0001047	core promoter binding(GO:0001047)
0.0	0.2	GO:0001054	RNA polymerase I activity(GO:0001054)
0.0	0.6	GO:0048487	beta-tubulin binding(GO:0048487)
0.0	1.1	GO:0015020	glucuronosyltransferase activity(GO:0015020)
0.0	1.2	GO:0005178	integrin binding(GO:0005178)
0.0	1.0	GO:0051219	phosphoprotein binding(GO:0051219)

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