Motif ID: Trp73

Z-value: 0.583


Transcription factors associated with Trp73:

Gene SymbolEntrez IDGene Name
Trp73 ENSMUSG00000029026.10 Trp73

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Trp73mm10_v2_chr4_-_154097105_1540971730.047.6e-01Click!


Activity profile for motif Trp73.

activity profile for motif Trp73


Sorted Z-values histogram for motif Trp73

Sorted Z-values for motif Trp73



Network of associatons between targets according to the STRING database.



First level regulatory network of Trp73

PNG image of the network

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Top targets:


Showing 1 to 20 of 75 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_+_48261427 7.293 ENSMUST00000021810.1
 Id4
inhibitor of DNA binding 4
chr7_-_116038734 5.640 ENSMUST00000166877.1
 Sox6
SRY-box containing gene 6
chr1_+_135729147 4.653 ENSMUST00000027677.7
 Csrp1
cysteine and glycine-rich protein 1
chrX_+_10717390 4.061 ENSMUST00000115524.1
ENSMUST00000008179.6
 Mid1ip1

Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish))

chr7_-_116308241 4.039 ENSMUST00000183057.1
ENSMUST00000182487.1
ENSMUST00000181998.1
 Plekha7


pleckstrin homology domain containing, family A member 7


chr3_+_159839729 3.863 ENSMUST00000068952.5
 Wls
wntless homolog (Drosophila)
chrX_+_10717451 3.729 ENSMUST00000156321.1
 Mid1ip1
Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish))
chr12_-_45074112 3.654 ENSMUST00000120531.1
ENSMUST00000143376.1
 Stxbp6

syntaxin binding protein 6 (amisyn)

chr1_-_5070281 3.451 ENSMUST00000147158.1
ENSMUST00000118000.1
 Rgs20

regulator of G-protein signaling 20

chr12_-_45074457 3.370 ENSMUST00000053768.6
 Stxbp6
syntaxin binding protein 6 (amisyn)
chr7_-_141443314 3.362 ENSMUST00000106005.2
 Lrdd
leucine-rich and death domain containing
chr1_+_153665274 3.282 ENSMUST00000152114.1
ENSMUST00000111812.1
 Rgs8

regulator of G-protein signaling 8

chr16_-_17125106 3.036 ENSMUST00000093336.6
 2610318N02Rik
RIKEN cDNA 2610318N02 gene
chr18_+_56432116 2.743 ENSMUST00000070166.5
 Gramd3
GRAM domain containing 3
chr4_+_101068983 2.615 ENSMUST00000038463.8
ENSMUST00000106955.1
 Raver2

ribonucleoprotein, PTB-binding 2

chr1_+_72824482 2.586 ENSMUST00000047328.4
 Igfbp2
insulin-like growth factor binding protein 2
chr2_-_164857542 2.526 ENSMUST00000109316.1
ENSMUST00000156255.1
ENSMUST00000128110.1
ENSMUST00000109317.3
 Pltp



phospholipid transfer protein



chr2_-_164857671 2.462 ENSMUST00000059954.7
 Pltp
phospholipid transfer protein
chr4_+_62583568 2.439 ENSMUST00000098031.3
 Rgs3
regulator of G-protein signaling 3
chr15_+_99055164 2.267 ENSMUST00000047104.7
ENSMUST00000024249.3
 Prph

peripherin


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 40 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 7.8 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
1.8 7.3 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.9 7.0 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.5 5.6 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
1.2 5.0 GO:0042360 vitamin E metabolic process(GO:0042360)
0.7 4.0 GO:0045218 zonula adherens maintenance(GO:0045218)
0.4 3.9 GO:0031017 exocrine pancreas development(GO:0031017)
0.3 3.5 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.3 3.3 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 2.7 GO:0070527 platelet aggregation(GO:0070527)
0.2 2.6 GO:0042104 positive regulation of activated T cell proliferation(GO:0042104)
0.1 2.3 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.2 1.8 GO:0071493 cellular response to UV-B(GO:0071493) replicative senescence(GO:0090399)
0.1 1.8 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.6 1.7 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 1.6 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.0 1.5 GO:0006730 one-carbon metabolic process(GO:0006730)
0.5 1.4 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.1 1.3 GO:0002467 germinal center formation(GO:0002467)
0.1 1.2 GO:0043248 proteasome assembly(GO:0043248)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 7.0 GO:0000145 exocyst(GO:0000145)
0.0 6.6 GO:0005667 transcription factor complex(GO:0005667)
0.0 6.5 GO:0005925 focal adhesion(GO:0005925)
0.0 6.4 GO:0005874 microtubule(GO:0005874)
0.1 4.1 GO:0032839 dendrite cytoplasm(GO:0032839)
0.4 4.0 GO:0005915 zonula adherens(GO:0005915)
0.1 3.5 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 2.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 2.6 GO:0016324 apical plasma membrane(GO:0016324)
0.0 2.6 GO:0043209 myelin sheath(GO:0043209)
0.8 2.3 GO:0044299 C-fiber(GO:0044299)
0.6 1.8 GO:0070557 PCNA-p21 complex(GO:0070557)
0.1 1.8 GO:0032593 insulin-responsive compartment(GO:0032593)
0.2 1.3 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 1.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.4 1.1 GO:0000811 GINS complex(GO:0000811)
0.1 1.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 1.1 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 1.0 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.9 GO:0032809 neuronal cell body membrane(GO:0032809)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 7.9 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 7.4 GO:0008022 protein C-terminus binding(GO:0008022)
0.3 7.0 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 5.9 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.3 4.0 GO:0070097 delta-catenin binding(GO:0070097)
0.4 3.9 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.1 3.5 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 3.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.3 2.6 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 1.9 GO:0001047 core promoter binding(GO:0001047)
0.5 1.8 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 1.8 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.6 1.7 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 1.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.4 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 1.2 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.3 1.1 GO:0004954 icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955)
0.1 1.1 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 1.1 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 1.0 GO:0016920 pyroglutamyl-peptidase activity(GO:0016920)