Motif ID: Vsx1_Uncx_Prrx2_Shox2_Noto

Z-value: 1.317


Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Prrx2mm10_v2_chr2_+_30834972_308349720.692.5e-11Click!
Shox2mm10_v2_chr3_-_66981279_669813180.532.0e-06Click!
Uncxmm10_v2_chr5_+_139543889_1395439040.532.1e-06Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Vsx1_Uncx_Prrx2_Shox2_Noto

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_-_48665098 47.468 ENSMUST00000118578.1
Otx2
orthodenticle homolog 2 (Drosophila)
chr2_+_20737306 40.955 ENSMUST00000114606.1
ENSMUST00000114608.1
Etl4

enhancer trap locus 4

chr8_-_61902669 37.318 ENSMUST00000121785.1
ENSMUST00000034057.7
Palld

palladin, cytoskeletal associated protein

chr3_+_159839729 35.119 ENSMUST00000068952.5
Wls
wntless homolog (Drosophila)
chr14_-_118052235 33.211 ENSMUST00000022725.2
Dct
dopachrome tautomerase
chr5_+_139543889 31.729 ENSMUST00000174792.1
ENSMUST00000031523.8
Uncx

UNC homeobox

chr9_+_118478344 27.487 ENSMUST00000035020.8
Eomes
eomesodermin homolog (Xenopus laevis)
chr2_+_71528657 26.461 ENSMUST00000126400.1
Dlx1
distal-less homeobox 1
chr2_-_168767136 26.040 ENSMUST00000029061.5
ENSMUST00000103074.1
Sall4

sal-like 4 (Drosophila)

chr2_-_168767029 24.106 ENSMUST00000075044.3
Sall4
sal-like 4 (Drosophila)
chr7_-_49636847 22.964 ENSMUST00000032717.6
Dbx1
developing brain homeobox 1
chr17_+_34592248 22.878 ENSMUST00000038149.6
Pbx2
pre B cell leukemia homeobox 2
chr2_+_25372315 22.661 ENSMUST00000028329.6
ENSMUST00000114293.2
ENSMUST00000100323.2
Sapcd2


suppressor APC domain containing 2


chrX_-_60893430 22.102 ENSMUST00000135107.2
Sox3
SRY-box containing gene 3
chr13_-_53473074 22.094 ENSMUST00000021922.8
Msx2
msh homeobox 2
chr9_+_118478182 21.943 ENSMUST00000111763.1
Eomes
eomesodermin homolog (Xenopus laevis)
chr3_-_88410295 19.799 ENSMUST00000056370.7
Pmf1
polyamine-modulated factor 1
chr15_+_25773985 19.779 ENSMUST00000125667.1
Myo10
myosin X
chr4_-_97778042 17.771 ENSMUST00000146447.1
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr7_-_37773555 16.834 ENSMUST00000176534.1
Zfp536
zinc finger protein 536
chr12_+_38780284 16.821 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
Etv1


ets variant gene 1


chr10_-_45470201 16.654 ENSMUST00000079390.6
Lin28b
lin-28 homolog B (C. elegans)
chr3_+_122419772 13.637 ENSMUST00000029766.4
Bcar3
breast cancer anti-estrogen resistance 3
chr13_-_102905740 13.601 ENSMUST00000167462.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr7_-_115824699 13.313 ENSMUST00000169129.1
Sox6
SRY-box containing gene 6
chr13_-_102906046 12.720 ENSMUST00000171791.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr3_-_86548268 12.466 ENSMUST00000077524.3
Mab21l2
mab-21-like 2 (C. elegans)
chr13_+_89540636 12.047 ENSMUST00000022108.7
Hapln1
hyaluronan and proteoglycan link protein 1
chr5_-_62765618 12.036 ENSMUST00000159470.1
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr7_-_37772868 11.993 ENSMUST00000176205.1
Zfp536
zinc finger protein 536
chr2_-_72986716 11.914 ENSMUST00000112062.1
Gm11084
predicted gene 11084
chr3_-_154328634 11.770 ENSMUST00000167744.1
Lhx8
LIM homeobox protein 8
chr12_+_38780817 11.646 ENSMUST00000160856.1
Etv1
ets variant gene 1
chr19_+_59458372 11.607 ENSMUST00000062216.3
Emx2
empty spiracles homeobox 2
chr3_-_79841729 11.184 ENSMUST00000168038.1
Tmem144
transmembrane protein 144
chr4_+_136143497 11.144 ENSMUST00000008016.2
Id3
inhibitor of DNA binding 3
chr11_+_102604370 11.109 ENSMUST00000057893.5
Fzd2
frizzled homolog 2 (Drosophila)
chr11_+_60537978 11.093 ENSMUST00000044250.3
Alkbh5
alkB, alkylation repair homolog 5 (E. coli)
chr3_+_134236483 10.642 ENSMUST00000181904.1
ENSMUST00000053048.9
Cxxc4

CXXC finger 4

chr6_+_8948608 10.579 ENSMUST00000160300.1
Nxph1
neurexophilin 1
chr1_-_190170671 10.569 ENSMUST00000175916.1
Prox1
prospero-related homeobox 1
chr7_-_116198487 10.483 ENSMUST00000181981.1
Plekha7
pleckstrin homology domain containing, family A member 7
chr9_+_119063429 10.329 ENSMUST00000141185.1
ENSMUST00000126251.1
ENSMUST00000136561.1
Vill


villin-like


chr6_-_147264124 10.243 ENSMUST00000052296.6
Pthlh
parathyroid hormone-like peptide
chr4_-_58499398 10.048 ENSMUST00000107570.1
Lpar1
lysophosphatidic acid receptor 1
chr5_-_62766153 9.945 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr3_+_125404292 9.713 ENSMUST00000144344.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr12_+_38783503 9.237 ENSMUST00000159334.1
Etv1
ets variant gene 1
chr9_+_72806874 9.084 ENSMUST00000055535.8
Prtg
protogenin homolog (Gallus gallus)
chr3_+_125404072 8.979 ENSMUST00000173932.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr12_+_38781093 8.825 ENSMUST00000161513.1
Etv1
ets variant gene 1
chr1_-_190170178 8.694 ENSMUST00000177288.1
Prox1
prospero-related homeobox 1
chr11_-_50292302 8.600 ENSMUST00000059458.4
Maml1
mastermind like 1 (Drosophila)
chr18_+_56432116 8.485 ENSMUST00000070166.5
Gramd3
GRAM domain containing 3
chr16_-_26989974 8.413 ENSMUST00000089832.4
Gmnc
geminin coiled-coil domain containing
chr17_-_35697971 8.240 ENSMUST00000146472.1
Ddr1
discoidin domain receptor family, member 1
chr13_+_44121167 8.216 ENSMUST00000163056.1
ENSMUST00000159595.1
Gm5083

predicted gene 5083

chr2_-_28916412 8.151 ENSMUST00000050776.2
ENSMUST00000113849.1
Barhl1

BarH-like 1 (Drosophila)

chr14_+_79515618 8.011 ENSMUST00000110835.1
Elf1
E74-like factor 1
chr2_+_152754156 7.949 ENSMUST00000010020.5
Cox4i2
cytochrome c oxidase subunit IV isoform 2
chr12_+_38783455 7.526 ENSMUST00000161980.1
ENSMUST00000160701.1
Etv1

ets variant gene 1

chr10_+_26772477 7.486 ENSMUST00000039557.7
Arhgap18
Rho GTPase activating protein 18
chr6_-_124779686 7.235 ENSMUST00000147669.1
ENSMUST00000128697.1
ENSMUST00000032218.3
ENSMUST00000112475.2
Lrrc23



leucine rich repeat containing 23



chr3_-_66296807 7.230 ENSMUST00000029419.7
Veph1
ventricular zone expressed PH domain-containing 1
chr4_+_154960915 7.093 ENSMUST00000049621.6
Hes5
hairy and enhancer of split 5 (Drosophila)
chr7_-_66427469 6.969 ENSMUST00000015278.7
Aldh1a3
aldehyde dehydrogenase family 1, subfamily A3
chr8_-_84662841 6.856 ENSMUST00000060427.4
Ier2
immediate early response 2
chr9_+_96258697 6.820 ENSMUST00000179416.1
Tfdp2
transcription factor Dp 2
chr2_-_18048784 6.781 ENSMUST00000142856.1
Skida1
SKI/DACH domain containing 1
chr14_-_46390501 6.746 ENSMUST00000100676.2
Bmp4
bone morphogenetic protein 4
chr2_+_52038005 6.636 ENSMUST00000065927.5
Tnfaip6
tumor necrosis factor alpha induced protein 6
chr3_-_100489324 6.575 ENSMUST00000061455.8
Fam46c
family with sequence similarity 46, member C
chr7_+_144838590 6.371 ENSMUST00000105898.1
Fgf3
fibroblast growth factor 3
chr4_-_110292719 6.324 ENSMUST00000106601.1
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr17_-_49564262 6.320 ENSMUST00000057610.6
Daam2
dishevelled associated activator of morphogenesis 2
chr19_-_59170978 6.105 ENSMUST00000172821.2
Vax1
ventral anterior homeobox containing gene 1
chr2_-_147186389 6.060 ENSMUST00000109970.3
ENSMUST00000067075.5
Nkx2-2

NK2 homeobox 2

chr1_-_78968079 6.012 ENSMUST00000049117.5
Gm5830
predicted pseudogene 5830
chr2_-_58052832 5.991 ENSMUST00000090940.5
Ermn
ermin, ERM-like protein
chr5_-_77115145 5.960 ENSMUST00000081964.5
Hopx
HOP homeobox
chr1_-_163725123 5.946 ENSMUST00000159679.1
Mettl11b
methyltransferase like 11B
chr18_+_4993795 5.835 ENSMUST00000153016.1
Svil
supervillin
chr1_+_104768510 5.832 ENSMUST00000062528.8
Cdh20
cadherin 20
chr2_+_109917639 5.799 ENSMUST00000046548.7
ENSMUST00000111037.2
Lgr4

leucine-rich repeat-containing G protein-coupled receptor 4

chr6_+_15196949 5.699 ENSMUST00000151301.1
ENSMUST00000131414.1
ENSMUST00000140557.1
ENSMUST00000115469.1
Foxp2



forkhead box P2



chr18_-_80986578 5.650 ENSMUST00000057950.7
Sall3
sal-like 3 (Drosophila)
chr3_+_66219909 5.566 ENSMUST00000029421.5
Ptx3
pentraxin related gene
chr5_+_138187485 5.521 ENSMUST00000110934.2
Cnpy4
canopy 4 homolog (zebrafish)
chr2_-_28916668 5.478 ENSMUST00000113847.1
Barhl1
BarH-like 1 (Drosophila)
chr14_-_46390576 5.459 ENSMUST00000074077.5
Bmp4
bone morphogenetic protein 4
chr13_+_8202885 5.381 ENSMUST00000139438.1
ENSMUST00000135574.1
Adarb2

adenosine deaminase, RNA-specific, B2

chr11_+_94327984 5.275 ENSMUST00000107818.2
ENSMUST00000051221.6
Ankrd40

ankyrin repeat domain 40

chr5_+_135106881 5.263 ENSMUST00000005507.3
Mlxipl
MLX interacting protein-like
chrM_+_7005 5.221 ENSMUST00000082405.1
mt-Co2
mitochondrially encoded cytochrome c oxidase II
chr13_+_51408618 5.202 ENSMUST00000087978.3
S1pr3
sphingosine-1-phosphate receptor 3
chr16_+_45094036 5.053 ENSMUST00000061050.5
Ccdc80
coiled-coil domain containing 80
chr9_+_65890237 4.929 ENSMUST00000045802.6
2810417H13Rik
RIKEN cDNA 2810417H13 gene
chr1_-_172027269 4.816 ENSMUST00000027837.6
ENSMUST00000111264.1
Vangl2

vang-like 2 (van gogh, Drosophila)

chrX_+_56454871 4.791 ENSMUST00000039374.2
ENSMUST00000101553.2
Ddx26b

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B

chr10_+_88091070 4.758 ENSMUST00000048621.7
Pmch
pro-melanin-concentrating hormone
chr11_+_114851507 4.746 ENSMUST00000177952.1
Gprc5c
G protein-coupled receptor, family C, group 5, member C
chr8_-_120228221 4.735 ENSMUST00000183235.1
A330074K22Rik
RIKEN cDNA A330074K22 gene
chr5_+_15516489 4.687 ENSMUST00000178227.1
Gm21847
predicted gene, 21847
chr7_+_49910112 4.668 ENSMUST00000056442.5
Slc6a5
solute carrier family 6 (neurotransmitter transporter, glycine), member 5
chrX_-_74246534 4.636 ENSMUST00000101454.2
ENSMUST00000033699.6
Flna

filamin, alpha

chr9_+_35423582 4.593 ENSMUST00000154652.1
Cdon
cell adhesion molecule-related/down-regulated by oncogenes
chr14_-_48667508 4.563 ENSMUST00000144465.1
ENSMUST00000133479.1
ENSMUST00000119070.1
ENSMUST00000152018.1
Otx2



orthodenticle homolog 2 (Drosophila)



chr1_-_72284248 4.522 ENSMUST00000097698.4
ENSMUST00000027381.6
Pecr

peroxisomal trans-2-enoyl-CoA reductase

chr3_-_157925056 4.371 ENSMUST00000118539.1
Cth
cystathionase (cystathionine gamma-lyase)
chr13_-_97747373 4.370 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr15_-_9140374 4.369 ENSMUST00000096482.3
ENSMUST00000110585.2
Skp2

S-phase kinase-associated protein 2 (p45)

chr6_+_29859662 4.366 ENSMUST00000128927.2
Ahcyl2
S-adenosylhomocysteine hydrolase-like 2
chr13_-_78196373 4.319 ENSMUST00000125176.2
Nr2f1
nuclear receptor subfamily 2, group F, member 1
chr17_+_17402672 4.306 ENSMUST00000115576.2
Lix1
limb expression 1 homolog (chicken)
chrX_-_102157065 4.301 ENSMUST00000056904.2
Ercc6l
excision repair cross-complementing rodent repair deficiency complementation group 6 like
chr3_+_121291725 4.254 ENSMUST00000039442.7
Alg14
asparagine-linked glycosylation 14
chr7_+_125829653 4.178 ENSMUST00000124223.1
D430042O09Rik
RIKEN cDNA D430042O09 gene
chr1_+_109983737 4.115 ENSMUST00000172005.1
Cdh7
cadherin 7, type 2
chr7_-_37769624 4.098 ENSMUST00000175941.1
Zfp536
zinc finger protein 536
chr5_+_115235836 4.092 ENSMUST00000081497.6
Pop5
processing of precursor 5, ribonuclease P/MRP family (S. cerevisiae)
chr6_+_29859686 4.088 ENSMUST00000134438.1
Ahcyl2
S-adenosylhomocysteine hydrolase-like 2
chr3_+_122044428 4.026 ENSMUST00000013995.8
Abca4
ATP-binding cassette, sub-family A (ABC1), member 4
chr6_+_29859374 4.023 ENSMUST00000115238.3
Ahcyl2
S-adenosylhomocysteine hydrolase-like 2
chr6_+_134929118 3.989 ENSMUST00000185152.1
ENSMUST00000184504.1
RP23-45G16.5

RP23-45G16.5

chr14_+_73237891 3.947 ENSMUST00000044405.6
Lpar6
lysophosphatidic acid receptor 6
chr13_+_23575753 3.890 ENSMUST00000105105.1
Hist1h3d
histone cluster 1, H3d
chr4_+_8690399 3.839 ENSMUST00000127476.1
Chd7
chromodomain helicase DNA binding protein 7
chr7_-_45830776 3.818 ENSMUST00000107723.2
ENSMUST00000131384.1
Grwd1

glutamate-rich WD repeat containing 1

chr2_+_38341068 3.771 ENSMUST00000133661.1
Lhx2
LIM homeobox protein 2
chr19_-_15924560 3.572 ENSMUST00000162053.1
Psat1
phosphoserine aminotransferase 1
chr7_-_5014645 3.546 ENSMUST00000165320.1
Fiz1
Flt3 interacting zinc finger protein 1
chrX_+_9885622 3.541 ENSMUST00000067529.2
ENSMUST00000086165.3
Sytl5

synaptotagmin-like 5

chrX_-_139871637 3.532 ENSMUST00000033811.7
ENSMUST00000087401.5
Morc4

microrchidia 4

chr4_+_62583568 3.479 ENSMUST00000098031.3
Rgs3
regulator of G-protein signaling 3
chr2_+_83724397 3.389 ENSMUST00000028499.4
ENSMUST00000141725.1
ENSMUST00000111740.2
Itgav


integrin alpha V


chr1_+_153665274 3.295 ENSMUST00000152114.1
ENSMUST00000111812.1
Rgs8

regulator of G-protein signaling 8

chr1_+_153665666 3.217 ENSMUST00000111814.1
ENSMUST00000111810.1
Rgs8

regulator of G-protein signaling 8

chr3_-_17786834 3.199 ENSMUST00000099198.2
Gm10742
predicted gene 10742
chr2_+_71389239 3.198 ENSMUST00000028408.2
Hat1
histone aminotransferase 1
chr18_-_66022580 3.121 ENSMUST00000143990.1
Lman1
lectin, mannose-binding, 1
chr6_-_148946146 3.091 ENSMUST00000132696.1
Fam60a
family with sequence similarity 60, member A
chr4_-_24430838 3.081 ENSMUST00000183964.1
RP23-35K5.2
RP23-35K5.2
chr11_-_3931960 3.065 ENSMUST00000109990.1
ENSMUST00000020710.4
ENSMUST00000109989.3
ENSMUST00000109991.1
ENSMUST00000109993.2
Tcn2




transcobalamin 2




chr19_+_24875679 3.018 ENSMUST00000073080.5
Gm10053
predicted gene 10053
chr16_+_45093611 3.018 ENSMUST00000099498.2
Ccdc80
coiled-coil domain containing 80
chr5_-_138187177 3.001 ENSMUST00000110937.1
ENSMUST00000139276.1
ENSMUST00000048698.7
ENSMUST00000123415.1
Taf6



TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor



chr10_+_73821857 2.959 ENSMUST00000177128.1
ENSMUST00000064562.7
ENSMUST00000129404.2
ENSMUST00000105426.3
ENSMUST00000131321.2
ENSMUST00000126920.2
ENSMUST00000147189.2
ENSMUST00000105424.3
ENSMUST00000092420.6
ENSMUST00000105429.3
ENSMUST00000131724.2
ENSMUST00000152655.2
ENSMUST00000151116.2
ENSMUST00000155701.2
ENSMUST00000152819.2
ENSMUST00000125517.2
ENSMUST00000124046.1
ENSMUST00000149977.2
ENSMUST00000146682.1
ENSMUST00000177107.1
Pcdh15



















protocadherin 15



















chr15_-_50890041 2.937 ENSMUST00000077935.5
Trps1
trichorhinophalangeal syndrome I (human)
chr10_+_128337761 2.905 ENSMUST00000005826.7
Cs
citrate synthase
chr8_-_45382198 2.847 ENSMUST00000093526.6
Fam149a
family with sequence similarity 149, member A
chr11_-_3931789 2.827 ENSMUST00000109992.1
ENSMUST00000109988.1
Tcn2

transcobalamin 2

chr11_+_98798653 2.718 ENSMUST00000037930.6
Msl1
male-specific lethal 1 homolog (Drosophila)
chr10_+_37139558 2.665 ENSMUST00000062667.3
5930403N24Rik
RIKEN cDNA 5930403N24 gene
chr4_-_154636831 2.658 ENSMUST00000030902.6
ENSMUST00000105637.1
ENSMUST00000070313.7
ENSMUST00000105636.1
ENSMUST00000105638.2
ENSMUST00000097759.2
ENSMUST00000124771.1
Prdm16






PR domain containing 16






chr1_+_153665587 2.658 ENSMUST00000147700.1
Rgs8
regulator of G-protein signaling 8
chr4_-_42168603 2.649 ENSMUST00000098121.3
Gm13305
predicted gene 13305
chr13_-_81570640 2.615 ENSMUST00000109565.2
Gpr98
G protein-coupled receptor 98
chr15_-_8710734 2.598 ENSMUST00000005493.7
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chrX_+_150547375 2.564 ENSMUST00000066337.6
ENSMUST00000112715.1
Alas2

aminolevulinic acid synthase 2, erythroid

chr14_+_54259227 2.545 ENSMUST00000041197.7
Abhd4
abhydrolase domain containing 4
chr6_+_63255971 2.537 ENSMUST00000159561.1
ENSMUST00000095852.3
Grid2

glutamate receptor, ionotropic, delta 2

chr1_+_153665627 2.529 ENSMUST00000147482.1
Rgs8
regulator of G-protein signaling 8
chr19_+_55895508 2.468 ENSMUST00000111646.1
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr2_+_132847719 2.445 ENSMUST00000124836.1
ENSMUST00000154160.1
Crls1

cardiolipin synthase 1

chr15_-_34495180 2.429 ENSMUST00000022946.5
Hrsp12
heat-responsive protein 12
chr4_-_132510493 2.413 ENSMUST00000030724.8
Sesn2
sestrin 2
chr10_-_80421847 2.381 ENSMUST00000156244.1
Tcf3
transcription factor 3
chrM_+_2743 2.377 ENSMUST00000082392.1
mt-Nd1
mitochondrially encoded NADH dehydrogenase 1
chr3_+_55782500 2.345 ENSMUST00000075422.4
Mab21l1
mab-21-like 1 (C. elegans)
chr6_+_7555053 2.339 ENSMUST00000090679.2
ENSMUST00000184986.1
Tac1

tachykinin 1

chr11_+_52098681 2.309 ENSMUST00000020608.2
Ppp2ca
protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform
chr1_-_14310198 2.271 ENSMUST00000168081.2
ENSMUST00000027066.6
Eya1

eyes absent 1 homolog (Drosophila)

chr1_+_137928100 2.266 ENSMUST00000054333.2
A130050O07Rik
RIKEN cDNA A130050O07 gene
chr12_-_57546121 2.246 ENSMUST00000044380.6
Foxa1
forkhead box A1
chr12_-_111813834 2.230 ENSMUST00000021715.5
Xrcc3
X-ray repair complementing defective repair in Chinese hamster cells 3
chr15_-_8710409 2.192 ENSMUST00000157065.1
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr11_-_31671863 2.180 ENSMUST00000058060.7
Bod1
biorientation of chromosomes in cell division 1
chr2_+_181767040 2.179 ENSMUST00000108756.1
Myt1
myelin transcription factor 1
chr7_+_28881656 2.166 ENSMUST00000066880.4
Capn12
calpain 12
chr2_-_30093642 2.151 ENSMUST00000102865.4
Zdhhc12
zinc finger, DHHC domain containing 12
chr2_+_9882622 2.133 ENSMUST00000114919.1
4930412O13Rik
RIKEN cDNA 4930412O13 gene
chr12_+_52516077 2.130 ENSMUST00000110725.1
Arhgap5
Rho GTPase activating protein 5
chr3_-_49757257 2.120 ENSMUST00000035931.7
Pcdh18
protocadherin 18
chr7_+_114745685 2.119 ENSMUST00000136645.1
ENSMUST00000169913.1
Insc

inscuteable homolog (Drosophila)

chr18_+_4920509 2.095 ENSMUST00000126977.1
Svil
supervillin
chr2_+_181767283 2.066 ENSMUST00000108757.2
Myt1
myelin transcription factor 1
chr18_+_34758890 2.063 ENSMUST00000049281.5
Fam53c
family with sequence similarity 53, member C
chr15_-_13173607 2.060 ENSMUST00000036439.4
Cdh6
cadherin 6
chr10_-_53647080 2.058 ENSMUST00000169866.1
Fam184a
family with sequence similarity 184, member A
chrX_+_159303266 2.012 ENSMUST00000112491.1
Rps6ka3
ribosomal protein S6 kinase polypeptide 3
chr9_-_96437434 2.004 ENSMUST00000070500.2
BC043934
cDNA sequence BC043934
chr9_-_71163224 1.999 ENSMUST00000074465.2
Aqp9
aquaporin 9
chr12_-_40037387 1.984 ENSMUST00000146905.1
Arl4a
ADP-ribosylation factor-like 4A
chr13_-_114458720 1.983 ENSMUST00000022287.5
Fst
follistatin
chr2_-_27475622 1.972 ENSMUST00000138693.1
ENSMUST00000113941.2
ENSMUST00000077737.6
Brd3


bromodomain containing 3


chr8_+_23411490 1.966 ENSMUST00000033952.7
Sfrp1
secreted frizzled-related protein 1
chr6_-_148831448 1.963 ENSMUST00000048418.7
Ipo8
importin 8
chr13_+_75707484 1.914 ENSMUST00000001583.6
Ell2
elongation factor RNA polymerase II 2
chr18_+_61639542 1.883 ENSMUST00000183083.1
ENSMUST00000183087.1
Gm20748

predicted gene, 20748

chr7_-_73541738 1.875 ENSMUST00000169922.2
Chd2
chromodomain helicase DNA binding protein 2

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
16.5 49.4 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
13.0 52.0 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
8.8 26.5 GO:0021893 cerebral cortex GABAergic interneuron fate commitment(GO:0021893)
7.4 22.1 GO:0048818 embryonic nail plate morphogenesis(GO:0035880) positive regulation of hair follicle maturation(GO:0048818) positive regulation of catagen(GO:0051795) frontal suture morphogenesis(GO:0060364)
6.4 19.3 GO:0090425 hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
5.5 33.2 GO:0006570 tyrosine metabolic process(GO:0006570)
4.1 12.2 GO:0048389 BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134) intermediate mesoderm development(GO:0048389) regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994) pattern specification involved in mesonephros development(GO:0061227) regulation of hepatocyte differentiation(GO:0070366) comma-shaped body morphogenesis(GO:0072049) S-shaped body morphogenesis(GO:0072050) anterior/posterior pattern specification involved in kidney development(GO:0072098) negative regulation of glomerular mesangial cell proliferation(GO:0072125) ureter urothelium development(GO:0072190) negative regulation of glomerulus development(GO:0090194) regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
4.0 31.7 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
3.5 7.1 GO:2000974 negative regulation of pro-B cell differentiation(GO:2000974)
3.2 15.9 GO:0003150 muscular septum morphogenesis(GO:0003150)
3.0 6.1 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
2.9 8.6 GO:0003162 atrioventricular node development(GO:0003162)
2.8 50.1 GO:0001833 inner cell mass cell proliferation(GO:0001833)
2.8 11.1 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
2.7 35.1 GO:0031017 exocrine pancreas development(GO:0031017)
2.5 10.0 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
2.5 37.3 GO:0071803 positive regulation of podosome assembly(GO:0071803)
2.3 7.0 GO:0060166 olfactory pit development(GO:0060166)
2.2 8.6 GO:0048752 semicircular canal morphogenesis(GO:0048752)
2.1 23.0 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
2.0 32.7 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
2.0 64.5 GO:0007638 mechanosensory behavior(GO:0007638)
2.0 5.9 GO:0015889 cobalamin transport(GO:0015889)
1.9 5.8 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
1.9 5.6 GO:0008228 opsonization(GO:0008228) modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
1.9 16.7 GO:0010587 miRNA catabolic process(GO:0010587)
1.8 5.3 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)
1.7 10.5 GO:0045218 zonula adherens maintenance(GO:0045218)
1.6 4.9 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)
1.6 13.0 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
1.6 4.8 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
1.5 13.3 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
1.4 22.1 GO:0007530 sex determination(GO:0007530)
1.3 7.9 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
1.3 3.8 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
1.3 10.2 GO:0021796 cerebral cortex regionalization(GO:0021796)
1.3 3.8 GO:0021978 telencephalon regionalization(GO:0021978)
1.2 3.6 GO:2000852 regulation of corticosterone secretion(GO:2000852)
1.1 5.7 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
1.1 10.2 GO:0043129 surfactant homeostasis(GO:0043129)
1.1 3.4 GO:0010871 negative regulation of receptor biosynthetic process(GO:0010871)
1.1 2.2 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
1.0 6.0 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
1.0 2.0 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
1.0 11.7 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.9 1.8 GO:0061743 motor learning(GO:0061743)
0.8 2.4 GO:0090526 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.8 4.7 GO:0036233 glycine import(GO:0036233)
0.8 6.1 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.7 17.2 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.7 3.6 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.7 4.2 GO:0060539 diaphragm development(GO:0060539)
0.7 8.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.7 4.1 GO:0009249 protein lipoylation(GO:0009249)
0.7 2.0 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.7 4.6 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.6 3.2 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.6 14.7 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.6 1.9 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.6 2.4 GO:0002326 B cell lineage commitment(GO:0002326)
0.6 11.1 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.6 5.2 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.6 2.2 GO:0000707 meiotic DNA recombinase assembly(GO:0000707) resolution of recombination intermediates(GO:0071139)
0.5 4.4 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.5 8.0 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.4 0.8 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.4 4.9 GO:0019985 translesion synthesis(GO:0019985)
0.4 1.6 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.4 12.2 GO:0006270 DNA replication initiation(GO:0006270)
0.4 2.3 GO:0034047 regulation of protein phosphatase type 2A activity(GO:0034047)
0.4 2.7 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.4 3.0 GO:0050957 equilibrioception(GO:0050957)
0.4 40.7 GO:0048706 embryonic skeletal system development(GO:0048706)
0.4 2.5 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) myoblast fate commitment(GO:0048625) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.3 2.4 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.3 4.5 GO:0030497 fatty acid elongation(GO:0030497)
0.3 1.9 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.3 1.8 GO:0052695 cellular glucuronidation(GO:0052695)
0.3 1.2 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.3 1.5 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.3 2.0 GO:0032782 urea transport(GO:0015840) bile acid secretion(GO:0032782) urea transmembrane transport(GO:0071918)
0.3 2.5 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.2 0.5 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.2 0.5 GO:0060023 soft palate development(GO:0060023)
0.2 5.7 GO:0035136 forelimb morphogenesis(GO:0035136)
0.2 1.4 GO:0016078 tRNA catabolic process(GO:0016078)
0.2 10.3 GO:0051693 actin filament capping(GO:0051693)
0.2 4.1 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.2 1.1 GO:0051697 protein delipidation(GO:0051697)
0.2 1.4 GO:0016584 nucleosome positioning(GO:0016584)
0.2 2.0 GO:0071763 nuclear membrane organization(GO:0071763)
0.2 0.6 GO:0010835 regulation of protein ADP-ribosylation(GO:0010835)
0.2 2.9 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.2 1.7 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.2 4.5 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.2 1.7 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.2 1.5 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.2 3.5 GO:0018345 protein palmitoylation(GO:0018345)
0.2 5.9 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.2 4.3 GO:0097352 autophagosome maturation(GO:0097352)
0.2 0.7 GO:0090365 regulation of mRNA modification(GO:0090365)
0.2 0.5 GO:0042420 dopamine catabolic process(GO:0042420)
0.2 1.3 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.2 1.3 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.1 7.5 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.1 0.7 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.1 1.5 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.1 0.5 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1 3.9 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 1.4 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.1 4.0 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.1 13.6 GO:0007605 sensory perception of sound(GO:0007605)
0.1 2.1 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.6 GO:0003161 cardiac conduction system development(GO:0003161)
0.1 0.3 GO:0035633 maintenance of blood-brain barrier(GO:0035633)
0.1 3.5 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 19.2 GO:0008360 regulation of cell shape(GO:0008360)
0.1 2.2 GO:0033194 response to hydroperoxide(GO:0033194)
0.1 1.4 GO:0006006 glucose metabolic process(GO:0006006)
0.1 1.1 GO:0099625 regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307) ventricular cardiac muscle cell membrane repolarization(GO:0099625)
0.1 5.2 GO:0071774 response to fibroblast growth factor(GO:0071774)
0.1 0.8 GO:0003351 epithelial cilium movement(GO:0003351)
0.1 0.5 GO:0010359 regulation of anion channel activity(GO:0010359)
0.1 1.0 GO:0080111 DNA demethylation(GO:0080111)
0.1 2.6 GO:0006783 heme biosynthetic process(GO:0006783)
0.1 6.3 GO:0043488 regulation of mRNA stability(GO:0043488)
0.1 2.0 GO:0050873 brown fat cell differentiation(GO:0050873)
0.1 6.3 GO:0007368 determination of left/right symmetry(GO:0007368)
0.1 6.6 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.1 10.6 GO:0030178 negative regulation of Wnt signaling pathway(GO:0030178)
0.1 0.6 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.1 0.9 GO:0006999 nuclear pore organization(GO:0006999)
0.1 1.4 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 3.1 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.1 2.5 GO:0019915 lipid storage(GO:0019915)
0.1 0.5 GO:0046929 negative regulation of neurotransmitter secretion(GO:0046929)
0.1 0.7 GO:0046548 retinal rod cell development(GO:0046548)
0.0 4.2 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 1.3 GO:0007566 embryo implantation(GO:0007566)
0.0 1.9 GO:0002224 toll-like receptor signaling pathway(GO:0002224)
0.0 0.5 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 10.5 GO:0007059 chromosome segregation(GO:0007059)
0.0 2.1 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.1 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536) lung vasculature development(GO:0060426)
0.0 0.7 GO:0071384 cellular response to corticosteroid stimulus(GO:0071384) cellular response to glucocorticoid stimulus(GO:0071385)
0.0 1.3 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.0 1.0 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.1 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.0 0.9 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.4 GO:0000132 establishment of mitotic spindle orientation(GO:0000132) establishment of mitotic spindle localization(GO:0040001)
0.0 0.4 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 1.0 GO:0006284 base-excision repair(GO:0006284)
0.0 1.4 GO:0022900 electron transport chain(GO:0022900)
0.0 1.8 GO:0050953 visual perception(GO:0007601) sensory perception of light stimulus(GO:0050953)
0.0 0.6 GO:0006101 tricarboxylic acid cycle(GO:0006099) citrate metabolic process(GO:0006101)
0.0 1.9 GO:0051028 mRNA transport(GO:0051028)
0.0 0.4 GO:0002053 positive regulation of mesenchymal cell proliferation(GO:0002053)
0.0 1.2 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)
0.0 2.4 GO:1902593 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.0 0.5 GO:0001525 angiogenesis(GO:0001525)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 19.8 GO:0000444 MIS12/MIND type complex(GO:0000444)
2.0 11.8 GO:0001674 female germ cell nucleus(GO:0001674)
1.8 5.5 GO:0000172 ribonuclease MRP complex(GO:0000172)
1.7 8.6 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
1.5 37.3 GO:0002102 podosome(GO:0002102)
1.3 33.2 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
1.2 4.8 GO:0060187 cell pole(GO:0060187)
1.1 5.7 GO:0031523 Myb complex(GO:0031523)
1.1 3.4 GO:0034684 integrin alphav-beta5 complex(GO:0034684)
1.1 35.1 GO:0032839 dendrite cytoplasm(GO:0032839)
1.0 7.9 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
1.0 10.5 GO:0005915 zonula adherens(GO:0005915)
0.7 6.0 GO:0033269 internode region of axon(GO:0033269)
0.5 2.7 GO:0072487 MSL complex(GO:0072487)
0.5 8.0 GO:0005614 interstitial matrix(GO:0005614)
0.5 6.3 GO:0042788 polysomal ribosome(GO:0042788)
0.4 2.2 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.4 1.3 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.4 49.7 GO:0000792 heterochromatin(GO:0000792)
0.4 1.8 GO:0044301 climbing fiber(GO:0044301)
0.4 19.8 GO:0016459 myosin complex(GO:0016459)
0.3 11.0 GO:0032809 neuronal cell body membrane(GO:0032809)
0.3 4.8 GO:0043205 fibril(GO:0043205)
0.3 2.5 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.3 3.8 GO:0042555 MCM complex(GO:0042555)
0.2 7.3 GO:0000788 nuclear nucleosome(GO:0000788)
0.2 2.4 GO:0061700 GATOR2 complex(GO:0061700)
0.2 3.1 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.2 0.9 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.2 3.1 GO:0016580 Sin3 complex(GO:0016580)
0.2 1.3 GO:0030478 actin cap(GO:0030478)
0.2 66.1 GO:0005667 transcription factor complex(GO:0005667)
0.1 0.7 GO:0070826 paraferritin complex(GO:0070826)
0.1 3.8 GO:0043034 costamere(GO:0043034)
0.1 8.5 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 7.3 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 2.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 12.6 GO:0016607 nuclear speck(GO:0016607)
0.1 9.0 GO:0043198 dendritic shaft(GO:0043198)
0.1 0.7 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 22.9 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 14.6 GO:0030427 site of polarized growth(GO:0030427)
0.1 1.1 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.1 0.4 GO:0042405 nuclear inclusion body(GO:0042405)
0.1 1.5 GO:0097440 apical dendrite(GO:0097440)
0.1 7.4 GO:0000776 kinetochore(GO:0000776)
0.1 4.5 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 1.4 GO:0000786 nucleosome(GO:0000786)
0.1 0.6 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 4.0 GO:0070469 respiratory chain(GO:0070469)
0.1 1.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 1.2 GO:0044439 microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.1 10.0 GO:0005925 focal adhesion(GO:0005925)
0.1 2.3 GO:0032993 protein-DNA complex(GO:0032993)
0.1 0.7 GO:0045120 pronucleus(GO:0045120)
0.0 0.1 GO:0000178 cytoplasmic exosome (RNase complex)(GO:0000177) exosome (RNase complex)(GO:0000178)
0.0 3.8 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.0 2.5 GO:0005811 lipid particle(GO:0005811)
0.0 220.4 GO:0005634 nucleus(GO:0005634)
0.0 0.8 GO:0005871 kinesin complex(GO:0005871)
0.0 1.3 GO:0000313 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.0 6.0 GO:0019866 mitochondrial inner membrane(GO:0005743) organelle inner membrane(GO:0019866)
0.0 0.4 GO:0046658 anchored component of plasma membrane(GO:0046658)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.2 41.6 GO:0031852 mu-type opioid receptor binding(GO:0031852)
2.8 11.1 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
2.5 37.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
2.4 19.3 GO:0050693 LBD domain binding(GO:0050693)
2.4 33.2 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
2.3 15.9 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
1.9 5.6 GO:0005118 sevenless binding(GO:0005118)
1.9 13.0 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
1.8 5.5 GO:0000171 ribonuclease MRP activity(GO:0000171)
1.7 10.0 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
1.5 19.8 GO:0043522 leucine zipper domain binding(GO:0043522)
1.5 4.5 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
1.4 7.0 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
1.4 12.2 GO:0039706 co-receptor binding(GO:0039706)
1.2 2.4 GO:0070644 vitamin D response element binding(GO:0070644)
1.1 5.6 GO:0001849 complement component C1q binding(GO:0001849)
1.1 18.7 GO:0005540 hyaluronic acid binding(GO:0005540)
1.0 4.8 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.9 8.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.9 9.0 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.9 10.5 GO:0070097 delta-catenin binding(GO:0070097)
0.8 5.9 GO:0031419 cobalamin binding(GO:0031419)
0.8 48.9 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.8 4.7 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.7 5.9 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.7 22.2 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.7 8.3 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.7 3.4 GO:0019960 C-X3-C chemokine binding(GO:0019960) neuregulin binding(GO:0038132)
0.7 5.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.6 13.7 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.6 13.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.5 4.4 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.5 2.4 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572)
0.5 2.9 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.5 5.8 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.5 22.0 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.4 126.6 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.4 1.6 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.4 2.4 GO:0070728 leucine binding(GO:0070728)
0.4 13.2 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.4 2.2 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.4 8.1 GO:0001968 fibronectin binding(GO:0001968)
0.3 1.0 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.3 2.0 GO:0015265 urea channel activity(GO:0015265)
0.3 8.6 GO:0042605 peptide antigen binding(GO:0042605)
0.3 5.2 GO:0004000 adenosine deaminase activity(GO:0004000)
0.3 32.9 GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982)
0.3 2.3 GO:1990405 protein antigen binding(GO:1990405)
0.3 1.4 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.3 1.4 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.3 15.7 GO:0030507 spectrin binding(GO:0030507)
0.3 190.9 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.3 0.5 GO:0051378 serotonin binding(GO:0051378)
0.2 3.1 GO:0005537 mannose binding(GO:0005537)
0.2 5.2 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.2 3.2 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.2 1.3 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.2 6.3 GO:0017091 AU-rich element binding(GO:0017091)
0.2 2.0 GO:0048185 activin binding(GO:0048185)
0.2 0.5 GO:0098809 nitrite reductase activity(GO:0098809)
0.2 1.1 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.2 3.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.2 3.6 GO:0008483 transaminase activity(GO:0008483)
0.1 0.6 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.7 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 2.0 GO:0005521 lamin binding(GO:0005521)
0.1 54.5 GO:0003779 actin binding(GO:0003779)
0.1 2.0 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 0.5 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 2.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 23.4 GO:0000287 magnesium ion binding(GO:0000287)
0.1 1.4 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 0.6 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 1.7 GO:0005542 folic acid binding(GO:0005542)
0.1 3.8 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 3.1 GO:0052771 coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771)
0.1 0.5 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.1 3.4 GO:0004386 helicase activity(GO:0004386)
0.1 3.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 0.7 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 0.6 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 0.2 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.1 2.1 GO:0042169 SH2 domain binding(GO:0042169)
0.1 1.0 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.1 2.3 GO:0016749 N-succinyltransferase activity(GO:0016749)
0.1 1.5 GO:0001671 ATPase activator activity(GO:0001671)
0.1 2.4 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 1.2 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 2.2 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.1 0.9 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 2.8 GO:0042393 histone binding(GO:0042393)
0.0 9.1 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.9 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 11.3 GO:0008134 transcription factor binding(GO:0008134)
0.0 0.7 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 3.2 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.4 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.1 GO:0016174 NAD(P)H oxidase activity(GO:0016174) mercury ion binding(GO:0045340)
0.0 1.8 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.6 GO:0005507 copper ion binding(GO:0005507)
0.0 3.6 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 17.5 GO:0044822 poly(A) RNA binding(GO:0044822)
0.0 0.8 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.5 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)