Motif ID: Xbp1_Creb3l1

Z-value: 0.880

Transcription factors associated with Xbp1_Creb3l1:

Gene SymbolEntrez IDGene Name
Creb3l1 ENSMUSG00000027230.9 Creb3l1
Xbp1 ENSMUSG00000020484.12 Xbp1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Xbp1mm10_v2_chr11_+_5520652_5520659-0.565.0e-07Click!
Creb3l1mm10_v2_chr2_-_92024502_920245290.281.8e-02Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Xbp1_Creb3l1

PNG image of the network

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Top targets:


Showing 1 to 20 of 168 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_45092130 20.231 ENSMUST00000148175.1
Rcn3
reticulocalbin 3, EF-hand calcium binding domain
chr7_-_45092198 16.523 ENSMUST00000140449.1
ENSMUST00000117546.1
ENSMUST00000019683.3
Rcn3


reticulocalbin 3, EF-hand calcium binding domain


chr15_+_79516396 14.905 ENSMUST00000010974.7
Kdelr3
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr7_-_45091713 10.744 ENSMUST00000141576.1
Rcn3
reticulocalbin 3, EF-hand calcium binding domain
chr2_-_105399286 10.200 ENSMUST00000006128.6
Rcn1
reticulocalbin 1
chr5_-_135251209 7.766 ENSMUST00000062572.2
Fzd9
frizzled homolog 9 (Drosophila)
chr3_+_93520473 7.090 ENSMUST00000029515.4
S100a11
S100 calcium binding protein A11 (calgizzarin)
chr6_-_54593139 6.860 ENSMUST00000046520.6
Fkbp14
FK506 binding protein 14
chr1_-_163313661 5.796 ENSMUST00000174397.1
ENSMUST00000075805.6
ENSMUST00000027878.7
Prrx1


paired related homeobox 1


chr4_-_137796350 5.776 ENSMUST00000030551.4
Alpl
alkaline phosphatase, liver/bone/kidney
chr7_+_128523576 5.729 ENSMUST00000033136.7
Bag3
BCL2-associated athanogene 3
chr13_-_38528412 4.889 ENSMUST00000035988.8
Txndc5
thioredoxin domain containing 5
chr3_+_96697100 4.492 ENSMUST00000107077.3
Pias3
protein inhibitor of activated STAT 3
chr15_-_32244632 4.388 ENSMUST00000181536.1
0610007N19Rik
RIKEN cDNA 0610007N19
chr6_-_101377342 4.299 ENSMUST00000151175.1
Pdzrn3
PDZ domain containing RING finger 3
chr10_+_91082940 4.212 ENSMUST00000020150.3
Ikbip
IKBKB interacting protein
chr3_+_96697076 4.147 ENSMUST00000162778.2
ENSMUST00000064900.9
Pias3

protein inhibitor of activated STAT 3

chr1_-_55226768 3.990 ENSMUST00000027121.8
ENSMUST00000114428.2
Rftn2

raftlin family member 2

chr14_-_79301623 3.824 ENSMUST00000022595.7
Rgcc
regulator of cell cycle
chr10_+_91083036 3.675 ENSMUST00000020149.5
Ikbip
IKBKB interacting protein

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 75 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.3 16.1 GO:0006621 protein retention in ER lumen(GO:0006621)
0.6 9.4 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.5 8.6 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 7.8 GO:0035567 non-canonical Wnt signaling pathway(GO:0035567)
0.7 7.3 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.1 6.3 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.4 5.8 GO:0048664 neuron fate determination(GO:0048664)
0.2 5.8 GO:0046677 response to antibiotic(GO:0046677)
0.0 5.5 GO:0043010 camera-type eye development(GO:0043010)
0.2 5.4 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.2 4.9 GO:0043277 apoptotic cell clearance(GO:0043277)
0.1 4.3 GO:0007528 neuromuscular junction development(GO:0007528)
0.6 4.0 GO:0032596 protein transport into membrane raft(GO:0032596) dsRNA transport(GO:0033227)
1.0 3.8 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.2 3.7 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.2 3.6 GO:0097154 GABAergic neuron differentiation(GO:0097154)
0.1 3.6 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.4 3.5 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.7 3.4 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.1 3.0 GO:0035855 megakaryocyte development(GO:0035855)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 81.3 GO:0005783 endoplasmic reticulum(GO:0005783)
0.2 8.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 8.6 GO:0005844 polysome(GO:0005844)
0.4 7.7 GO:0031527 filopodium membrane(GO:0031527)
0.4 5.8 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.1 5.7 GO:0030018 Z disc(GO:0030018)
0.1 5.0 GO:0005811 lipid particle(GO:0005811)
0.0 4.9 GO:0005667 transcription factor complex(GO:0005667)
0.1 4.3 GO:0031594 neuromuscular junction(GO:0031594)
0.3 3.7 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 3.5 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.8 3.4 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 3.3 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.4 3.0 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.2 2.8 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 2.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2 2.4 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 2.4 GO:0042734 presynaptic membrane(GO:0042734)
0.2 2.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 1.9 GO:0005741 mitochondrial outer membrane(GO:0005741)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 61 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 56.3 GO:0005509 calcium ion binding(GO:0005509)
4.0 16.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.3 8.6 GO:0019789 SUMO transferase activity(GO:0019789)
0.4 7.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.2 6.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
1.4 5.8 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.3 5.8 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.2 5.8 GO:0071837 HMG box domain binding(GO:0071837)
1.0 5.7 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 4.6 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.8 3.9 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.1 3.8 GO:0070412 R-SMAD binding(GO:0070412)
0.3 3.5 GO:0030274 LIM domain binding(GO:0030274)
0.1 3.2 GO:0020037 heme binding(GO:0020037)
0.1 3.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.7 2.8 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.4 2.7 GO:0070191 methionine-R-sulfoxide reductase activity(GO:0070191)
0.3 2.7 GO:0018741 alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902)
0.1 2.7 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 2.7 GO:0070064 proline-rich region binding(GO:0070064)