Motif ID: Yy1_Yy2

Z-value: 2.986

Transcription factors associated with Yy1_Yy2:

Gene SymbolEntrez IDGene Name
Yy1 ENSMUSG00000021264.11 Yy1
Yy2 ENSMUSG00000091736.2 Yy2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Yy2mm10_v2_chrX_-_157598642_157598655-0.482.6e-05Click!
Yy1mm10_v2_chr12_+_108792946_108792988-0.028.7e-01Click!


Activity profile for motif Yy1_Yy2.

activity profile for motif Yy1_Yy2


Sorted Z-values histogram for motif Yy1_Yy2

Sorted Z-values for motif Yy1_Yy2



Network of associatons between targets according to the STRING database.



First level regulatory network of Yy1_Yy2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_-_22163299 21.203 ENSMUST00000100052.4
 Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
chr19_+_25610533 17.909 ENSMUST00000048935.4
 Dmrt3
doublesex and mab-3 related transcription factor 3
chr11_+_94741782 13.804 ENSMUST00000021240.6
 Cdc34-ps
cell division cycle 34 homolog, pseudogene (S. cerevisiae)
chr3_+_146121655 12.411 ENSMUST00000039450.4
 Mcoln3
mucolipin 3
chr3_-_90213577 11.817 ENSMUST00000170122.2
 Rps27
ribosomal protein S27
chr17_-_23829095 11.459 ENSMUST00000069579.5
 Tceb2
transcription elongation factor B (SIII), polypeptide 2
chr7_-_103843154 11.014 ENSMUST00000063957.4
 Hbb-bh1
hemoglobin Z, beta-like embryonic chain
chr12_+_109459843 10.631 ENSMUST00000173812.1
 Dlk1
delta-like 1 homolog (Drosophila)
chr16_+_30065333 10.482 ENSMUST00000023171.7
 Hes1
hairy and enhancer of split 1 (Drosophila)
chr14_-_76237353 10.161 ENSMUST00000095471.4
 Rps2-ps6
ribosomal protein S2, pseudogene 6
chr10_-_128549102 10.141 ENSMUST00000176906.1
 Rpl41
ribosomal protein L41
chr7_-_78783026 9.834 ENSMUST00000032841.5
 Mrpl46
mitochondrial ribosomal protein L46
chr11_+_32276893 9.781 ENSMUST00000145569.1
 Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr8_-_107263248 9.692 ENSMUST00000080443.6
 Rps18-ps3
ribosomal protein S18, pseudogene 3
chr10_-_128549125 9.686 ENSMUST00000177163.1
ENSMUST00000176683.1
ENSMUST00000176010.1
 Rpl41


ribosomal protein L41


chr18_-_13972617 9.526 ENSMUST00000025288.7
 Zfp521
zinc finger protein 521
chr10_-_77113676 9.145 ENSMUST00000072755.4
ENSMUST00000105409.1
 Col18a1

collagen, type XVIII, alpha 1

chr9_+_50603892 9.101 ENSMUST00000044051.4
 Timm8b
translocase of inner mitochondrial membrane 8B
chr5_-_53707532 9.001 ENSMUST00000031093.3
 Cckar
cholecystokinin A receptor
chr7_+_29289300 8.849 ENSMUST00000048187.4
 Ppp1r14a
protein phosphatase 1, regulatory (inhibitor) subunit 14A

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 866 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 72.8 GO:0042254 ribosome biogenesis(GO:0042254)
2.0 63.0 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.2 53.1 GO:0006412 translation(GO:0006412)
1.2 49.2 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
2.0 44.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.9 43.1 GO:0032543 mitochondrial translation(GO:0032543)
1.5 41.7 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.4 36.5 GO:0051028 mRNA transport(GO:0051028)
0.5 32.8 GO:0006413 translational initiation(GO:0006413)
1.8 30.4 GO:0043248 proteasome assembly(GO:0043248)
0.7 27.2 GO:0002181 cytoplasmic translation(GO:0002181)
5.4 27.0 GO:0015671 oxygen transport(GO:0015671)
0.8 25.3 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
3.3 23.4 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.7 23.0 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.7 21.1 GO:0006270 DNA replication initiation(GO:0006270)
1.8 18.3 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
6.0 18.0 GO:1904274 tricellular tight junction assembly(GO:1904274)
1.3 17.6 GO:0010388 cullin deneddylation(GO:0010388)
0.7 17.4 GO:0006783 heme biosynthetic process(GO:0006783)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 350 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.1 156.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
2.2 102.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.3 87.0 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.1 63.9 GO:0005730 nucleolus(GO:0005730)
1.2 56.4 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
1.3 51.9 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
1.4 45.6 GO:0015935 small ribosomal subunit(GO:0015935)
1.3 42.7 GO:0000788 nuclear nucleosome(GO:0000788)
0.9 38.6 GO:0000786 nucleosome(GO:0000786)
1.7 36.3 GO:0005839 proteasome core complex(GO:0005839)
0.0 31.7 GO:0005739 mitochondrion(GO:0005739)
0.6 31.6 GO:0005840 ribosome(GO:0005840)
0.6 29.0 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
2.9 23.6 GO:0005833 hemoglobin complex(GO:0005833)
0.5 23.5 GO:0008180 COP9 signalosome(GO:0008180)
2.2 19.8 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
1.6 19.6 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
1.1 18.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.3 17.9 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
2.9 17.5 GO:0061689 tricellular tight junction(GO:0061689)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 525 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.5 346.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 98.2 GO:0003723 RNA binding(GO:0003723)
0.8 48.8 GO:0003743 translation initiation factor activity(GO:0003743)
0.6 44.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
2.6 40.8 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 36.8 GO:0000987 core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
1.6 34.9 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
1.0 31.8 GO:0003954 NADH dehydrogenase activity(GO:0003954)
5.4 27.0 GO:0005344 oxygen transporter activity(GO:0005344)
0.3 27.0 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.5 24.0 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.6 23.6 GO:0008536 Ran GTPase binding(GO:0008536)
1.3 22.8 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.9 22.8 GO:0008432 JUN kinase binding(GO:0008432)
0.8 22.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.4 21.9 GO:0003684 damaged DNA binding(GO:0003684)
1.1 19.2 GO:0055103 ligase regulator activity(GO:0055103)
1.4 18.8 GO:0043024 ribosomal small subunit binding(GO:0043024)
1.2 17.3 GO:0001054 RNA polymerase I activity(GO:0001054)
0.3 17.1 GO:0003724 RNA helicase activity(GO:0003724)