Motif ID: Zbtb18

Z-value: 1.127


Transcription factors associated with Zbtb18:

Gene SymbolEntrez IDGene Name
Zbtb18 ENSMUSG00000063659.6 Zbtb18

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zbtb18mm10_v2_chr1_+_177445660_177445821-0.741.5e-13Click!


Activity profile for motif Zbtb18.

activity profile for motif Zbtb18


Sorted Z-values histogram for motif Zbtb18

Sorted Z-values for motif Zbtb18



Network of associatons between targets according to the STRING database.



First level regulatory network of Zbtb18

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_45311538 15.024 ENSMUST00000087883.6
Col3a1
collagen, type III, alpha 1
chr18_+_50051702 9.808 ENSMUST00000134348.1
ENSMUST00000153873.2
Tnfaip8

tumor necrosis factor, alpha-induced protein 8

chr11_-_102365111 8.326 ENSMUST00000006749.9
Slc4a1
solute carrier family 4 (anion exchanger), member 1
chr5_-_28467093 6.951 ENSMUST00000002708.3
Shh
sonic hedgehog
chr3_-_97610156 6.855 ENSMUST00000029730.4
Chd1l
chromodomain helicase DNA binding protein 1-like
chr9_-_20976762 6.798 ENSMUST00000054197.5
S1pr2
sphingosine-1-phosphate receptor 2
chr6_+_5390387 6.774 ENSMUST00000183358.1
Asb4
ankyrin repeat and SOCS box-containing 4
chr9_+_65630552 6.541 ENSMUST00000055844.8
Rbpms2
RNA binding protein with multiple splicing 2
chr7_-_19699008 6.304 ENSMUST00000174355.1
ENSMUST00000172983.1
ENSMUST00000174710.1
ENSMUST00000167646.2
ENSMUST00000003066.9
ENSMUST00000174064.1
Apoe





apolipoprotein E





chr14_-_20181773 6.189 ENSMUST00000024011.8
Kcnk5
potassium channel, subfamily K, member 5
chr16_+_91269759 6.018 ENSMUST00000056882.5
Olig1
oligodendrocyte transcription factor 1
chr14_-_122913085 5.823 ENSMUST00000162164.1
ENSMUST00000110679.2
ENSMUST00000038075.5
Ggact


gamma-glutamylamine cyclotransferase


chr10_+_78069351 5.807 ENSMUST00000105393.1
Icosl
icos ligand
chr6_+_135362931 5.728 ENSMUST00000032330.9
Emp1
epithelial membrane protein 1
chrX_-_106485367 5.461 ENSMUST00000140707.1
Fndc3c1
fibronectin type III domain containing 3C1
chr8_-_107403197 5.439 ENSMUST00000003947.8
Nqo1
NAD(P)H dehydrogenase, quinone 1
chr15_+_78926720 4.943 ENSMUST00000089377.5
Lgals1
lectin, galactose binding, soluble 1
chr3_+_134236483 4.797 ENSMUST00000181904.1
ENSMUST00000053048.9
Cxxc4

CXXC finger 4

chr12_+_109743787 4.780 ENSMUST00000183068.1
Mirg
miRNA containing gene
chr13_+_13437602 4.772 ENSMUST00000005532.7
Nid1
nidogen 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 212 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.0 15.0 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.5 11.2 GO:0015701 bicarbonate transport(GO:0015701)
0.2 9.8 GO:0032611 interleukin-1 beta production(GO:0032611)
0.5 8.0 GO:0032060 bleb assembly(GO:0032060)
0.4 7.8 GO:0045475 locomotor rhythm(GO:0045475)
0.4 7.3 GO:0051127 positive regulation of actin nucleation(GO:0051127)
0.3 7.2 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
2.3 7.0 GO:0060769 positive regulation of epithelial cell proliferation involved in prostate gland development(GO:0060769) kidney smooth muscle tissue development(GO:0072194) negative regulation of dopaminergic neuron differentiation(GO:1904339)
2.3 6.8 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.7 6.8 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.6 6.5 GO:0030322 stabilization of membrane potential(GO:0030322)
2.1 6.3 GO:2001139 negative regulation of postsynaptic membrane organization(GO:1901627) negative regulation of dendritic spine maintenance(GO:1902951) negative regulation of phospholipid efflux(GO:1902999) regulation of lipid transport across blood brain barrier(GO:1903000) negative regulation of lipid transport across blood brain barrier(GO:1903001) positive regulation of lipid transport across blood brain barrier(GO:1903002) negative regulation of phospholipid transport(GO:2001139)
0.1 6.0 GO:0048663 neuron fate commitment(GO:0048663)
1.9 5.8 GO:0045404 positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.0 5.6 GO:0043524 negative regulation of neuron apoptotic process(GO:0043524)
0.1 5.4 GO:0006801 superoxide metabolic process(GO:0006801)
1.7 5.1 GO:0060364 frontal suture morphogenesis(GO:0060364)
0.1 5.1 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
1.2 4.9 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
1.0 4.9 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 97 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.2 15.0 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 13.3 GO:0005884 actin filament(GO:0005884)
0.1 10.2 GO:0005657 replication fork(GO:0005657)
0.1 8.4 GO:0005882 intermediate filament(GO:0005882)
0.1 8.2 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 8.2 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 7.7 GO:0005604 basement membrane(GO:0005604)
1.7 6.8 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
2.1 6.3 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.1 5.9 GO:0014704 intercalated disc(GO:0014704)
0.1 5.7 GO:0016592 mediator complex(GO:0016592)
0.0 5.5 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.1 5.2 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 5.0 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.6 4.8 GO:0032009 early phagosome(GO:0032009)
0.3 4.8 GO:0097225 sperm midpiece(GO:0097225)
0.2 4.8 GO:0005605 basal lamina(GO:0005605)
0.1 4.2 GO:0005581 collagen trimer(GO:0005581)
0.0 4.2 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 4.0 GO:0005813 centrosome(GO:0005813)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 149 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.0 15.0 GO:0048407 platelet-derived growth factor binding(GO:0048407)
1.7 11.7 GO:0043237 laminin-1 binding(GO:0043237)
0.3 11.5 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.7 11.2 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
0.0 10.1 GO:0003735 structural constituent of ribosome(GO:0003735)
1.0 8.9 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 7.1 GO:0005509 calcium ion binding(GO:0005509)
0.8 6.8 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 6.8 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.6 6.5 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 6.5 GO:0051015 actin filament binding(GO:0051015)
2.1 6.3 GO:0046911 hydroxyapatite binding(GO:0046848) metal chelating activity(GO:0046911) phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.2 6.2 GO:0030332 cyclin binding(GO:0030332)
1.9 5.8 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
1.4 5.4 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 5.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
1.6 4.9 GO:0005534 galactose binding(GO:0005534)
0.4 4.8 GO:0005522 profilin binding(GO:0005522)
0.0 4.7 GO:0030165 PDZ domain binding(GO:0030165)
0.3 4.6 GO:0005540 hyaluronic acid binding(GO:0005540)