Motif ID: Zbtb4

Z-value: 0.630


Transcription factors associated with Zbtb4:

Gene SymbolEntrez IDGene Name
Zbtb4 ENSMUSG00000018750.8 Zbtb4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zbtb4mm10_v2_chr11_+_69765899_697659250.422.9e-04Click!


Activity profile for motif Zbtb4.

activity profile for motif Zbtb4


Sorted Z-values histogram for motif Zbtb4

Sorted Z-values for motif Zbtb4



Network of associatons between targets according to the STRING database.



First level regulatory network of Zbtb4

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_+_103422010 5.798 ENSMUST00000182089.1
Gm26992
predicted gene, 26992
chr16_+_11984581 3.887 ENSMUST00000170672.2
ENSMUST00000023138.7
Shisa9

shisa homolog 9 (Xenopus laevis)

chr1_+_34678176 3.617 ENSMUST00000159747.2
Arhgef4
Rho guanine nucleotide exchange factor (GEF) 4
chr2_+_124610278 3.268 ENSMUST00000051419.8
ENSMUST00000077847.5
ENSMUST00000078621.5
ENSMUST00000076335.5
Sema6d



sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D



chr2_-_170427828 2.924 ENSMUST00000013667.2
ENSMUST00000109152.2
ENSMUST00000068137.4
Bcas1


breast carcinoma amplified sequence 1


chr11_-_3504766 2.891 ENSMUST00000044507.5
Inpp5j
inositol polyphosphate 5-phosphatase J
chr2_+_124610573 2.831 ENSMUST00000103239.3
ENSMUST00000103240.2
Sema6d

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D

chr6_-_48841373 2.819 ENSMUST00000166247.1
Tmem176b
transmembrane protein 176B
chr11_+_100574904 2.491 ENSMUST00000103120.4
Cnp
2',3'-cyclic nucleotide 3' phosphodiesterase
chr6_+_141524379 2.434 ENSMUST00000032362.9
Slco1c1
solute carrier organic anion transporter family, member 1c1
chr6_+_48841476 2.382 ENSMUST00000101426.4
Tmem176a
transmembrane protein 176A
chr6_+_48841633 2.377 ENSMUST00000168406.1
Tmem176a
transmembrane protein 176A
chr7_-_19699008 2.202 ENSMUST00000174355.1
ENSMUST00000172983.1
ENSMUST00000174710.1
ENSMUST00000167646.2
ENSMUST00000003066.9
ENSMUST00000174064.1
Apoe





apolipoprotein E





chr6_-_48841098 2.168 ENSMUST00000101429.4
Tmem176b
transmembrane protein 176B
chr15_+_74563738 2.113 ENSMUST00000170845.1
Bai1
brain-specific angiogenesis inhibitor 1
chr9_-_70657121 2.109 ENSMUST00000049031.5
Fam63b
family with sequence similarity 63, member B
chr10_+_100015817 1.989 ENSMUST00000130190.1
ENSMUST00000020129.7
Kitl

kit ligand

chr2_-_73386396 1.841 ENSMUST00000112044.1
ENSMUST00000112043.1
ENSMUST00000076463.5
Gpr155


G protein-coupled receptor 155


chr18_-_39490649 1.841 ENSMUST00000115567.1
Nr3c1
nuclear receptor subfamily 3, group C, member 1
chr5_-_30105359 1.827 ENSMUST00000127749.3
3110082J24Rik
RIKEN cDNA 3110082J24 gene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 77 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.4 9.7 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.2 6.1 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.2 3.9 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 3.6 GO:0046847 filopodium assembly(GO:0046847)
0.1 2.9 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.1 2.8 GO:0001919 regulation of receptor recycling(GO:0001919)
0.6 2.5 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.3 2.5 GO:0006004 fucose metabolic process(GO:0006004)
0.3 2.5 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.1 2.5 GO:0008209 androgen metabolic process(GO:0008209)
0.1 2.5 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.2 2.4 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 2.4 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.7 2.2 GO:2001139 negative regulation of postsynaptic membrane organization(GO:1901627) negative regulation of dendritic spine maintenance(GO:1902951) negative regulation of phospholipid efflux(GO:1902999) regulation of lipid transport across blood brain barrier(GO:1903000) negative regulation of lipid transport across blood brain barrier(GO:1903001) positive regulation of lipid transport across blood brain barrier(GO:1903002) negative regulation of phospholipid transport(GO:2001139)
0.3 2.0 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.6 1.8 GO:0030070 insulin processing(GO:0030070)
0.4 1.8 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.2 1.6 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1 1.6 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.4 1.5 GO:0097494 regulation of vesicle size(GO:0097494)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 5.5 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.4 3.9 GO:0032591 dendritic spine membrane(GO:0032591)
0.4 3.0 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.3 2.9 GO:0043083 synaptic cleft(GO:0043083)
0.8 2.5 GO:0042642 actomyosin, myosin complex part(GO:0042642)
0.1 2.5 GO:0000145 exocyst(GO:0000145)
0.0 2.5 GO:0043198 dendritic shaft(GO:0043198)
0.0 2.5 GO:0017053 transcriptional repressor complex(GO:0017053)
0.7 2.2 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.1 1.6 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 1.5 GO:0031045 dense core granule(GO:0031045)
0.0 1.4 GO:0001669 acrosomal vesicle(GO:0001669)
0.3 1.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 1.0 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.8 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 0.7 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.7 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.7 GO:0014704 intercalated disc(GO:0014704)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 59 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 6.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 3.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 3.3 GO:0030165 PDZ domain binding(GO:0030165)
1.0 2.9 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.4 2.9 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.6 2.5 GO:0042806 fucose binding(GO:0042806)
0.2 2.5 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.1 2.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 2.5 GO:0004112 cyclic-nucleotide phosphodiesterase activity(GO:0004112)
0.6 2.4 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 2.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 2.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.7 2.2 GO:0046911 hydroxyapatite binding(GO:0046848) metal chelating activity(GO:0046911) phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.3 2.0 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.5 1.8 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.3 1.6 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) kainate selective glutamate receptor activity(GO:0015277)
0.3 1.6 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733)
0.1 1.6 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 1.5 GO:0019003 GDP binding(GO:0019003)
0.0 1.5 GO:0004222 metalloendopeptidase activity(GO:0004222)