Motif ID: Zbtb6

Z-value: 0.733


Transcription factors associated with Zbtb6:

Gene SymbolEntrez IDGene Name
Zbtb6 ENSMUSG00000066798.3 Zbtb6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zbtb6mm10_v2_chr2_-_37430835_374309190.458.9e-05Click!


Activity profile for motif Zbtb6.

activity profile for motif Zbtb6


Sorted Z-values histogram for motif Zbtb6

Sorted Z-values for motif Zbtb6



Network of associatons between targets according to the STRING database.



First level regulatory network of Zbtb6

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_102897123 6.266 ENSMUST00000067444.3
Gfap
glial fibrillary acidic protein
chr6_+_114131229 4.286 ENSMUST00000032451.7
Slc6a11
solute carrier family 6 (neurotransmitter transporter, GABA), member 11
chr11_-_102897146 4.067 ENSMUST00000077902.4
Gfap
glial fibrillary acidic protein
chr3_+_54156039 4.008 ENSMUST00000029311.6
Trpc4
transient receptor potential cation channel, subfamily C, member 4
chr6_+_124997062 3.856 ENSMUST00000159391.1
Pianp
PILR alpha associated neural protein
chr18_+_37504264 3.225 ENSMUST00000052179.6
Pcdhb20
protocadherin beta 20
chr6_+_124996681 3.202 ENSMUST00000032479.4
Pianp
PILR alpha associated neural protein
chr11_-_30025915 2.964 ENSMUST00000058902.5
Eml6
echinoderm microtubule associated protein like 6
chr4_-_120287349 2.905 ENSMUST00000102656.3
Foxo6
forkhead box O6
chr4_+_136286061 2.774 ENSMUST00000069195.4
ENSMUST00000130658.1
Zfp46

zinc finger protein 46

chr7_-_4789541 2.661 ENSMUST00000168578.1
Tmem238
transmembrane protein 238
chr15_+_103503261 2.604 ENSMUST00000023132.3
Pde1b
phosphodiesterase 1B, Ca2+-calmodulin dependent
chr10_+_7589788 2.592 ENSMUST00000134346.1
ENSMUST00000019931.5
Lrp11

low density lipoprotein receptor-related protein 11

chr1_-_133131782 2.556 ENSMUST00000180528.1
Gm26616
predicted gene, 26616
chr5_-_18360384 2.540 ENSMUST00000074694.5
Gnai1
guanine nucleotide binding protein (G protein), alpha inhibiting 1
chr10_+_7589885 2.438 ENSMUST00000130590.1
ENSMUST00000135907.1
Lrp11

low density lipoprotein receptor-related protein 11

chr11_+_101246405 2.393 ENSMUST00000122006.1
ENSMUST00000151830.1
Ramp2

receptor (calcitonin) activity modifying protein 2

chr6_-_60829826 2.303 ENSMUST00000163779.1
Snca
synuclein, alpha
chr18_+_37513652 2.281 ENSMUST00000061405.4
Pcdhb21
protocadherin beta 21
chr5_+_135806859 2.278 ENSMUST00000126232.1
Srrm3
serine/arginine repetitive matrix 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 89 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.7 10.3 GO:0010624 regulation of Schwann cell proliferation(GO:0010624)
0.4 9.0 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.3 5.6 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
1.3 5.0 GO:0009414 response to water deprivation(GO:0009414)
0.1 4.6 GO:1902476 chloride transmembrane transport(GO:1902476)
0.4 4.5 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
1.3 3.8 GO:0021837 motogenic signaling involved in postnatal olfactory bulb interneuron migration(GO:0021837) positive regulation of mitotic cell cycle DNA replication(GO:1903465)
0.4 3.6 GO:0007379 segment specification(GO:0007379)
0.5 3.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
1.0 3.0 GO:0006601 creatine biosynthetic process(GO:0006601)
0.0 2.9 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.4 2.6 GO:0036006 response to macrophage colony-stimulating factor(GO:0036005) cellular response to macrophage colony-stimulating factor stimulus(GO:0036006)
0.2 2.5 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.6 2.3 GO:0010040 response to iron(II) ion(GO:0010040) positive regulation of hydrogen peroxide metabolic process(GO:0010726) negative regulation of synaptic transmission, dopaminergic(GO:0032227) negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963) cellular response to copper ion(GO:0071280) regulation of peroxidase activity(GO:2000468)
0.0 2.3 GO:0008360 regulation of cell shape(GO:0008360)
0.2 2.2 GO:0071420 cellular response to histamine(GO:0071420)
0.0 2.2 GO:0008643 carbohydrate transport(GO:0008643)
0.1 2.1 GO:0021702 cerebellar Purkinje cell differentiation(GO:0021702)
0.1 2.0 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.6 1.9 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 46 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 10.8 GO:0043235 receptor complex(GO:0043235)
2.6 10.3 GO:0097450 astrocyte end-foot(GO:0097450)
0.0 9.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 9.3 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 8.6 GO:0000139 Golgi membrane(GO:0000139)
0.1 4.7 GO:0034704 calcium channel complex(GO:0034704)
0.0 3.7 GO:0043209 myelin sheath(GO:0043209)
0.0 3.2 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.1 2.7 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 2.5 GO:0030141 secretory granule(GO:0030141)
0.1 2.4 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 2.4 GO:0005776 autophagosome(GO:0005776)
0.6 2.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 2.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 2.2 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 1.9 GO:0070938 contractile ring(GO:0070938)
0.1 1.9 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 1.8 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 1.8 GO:0005783 endoplasmic reticulum(GO:0005783)
0.4 1.7 GO:0031084 BLOC-2 complex(GO:0031084)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 68 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 10.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.3 7.8 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.2 4.6 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.2 4.5 GO:0015026 coreceptor activity(GO:0015026)
1.4 4.3 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.3 4.0 GO:0015279 store-operated calcium channel activity(GO:0015279) inositol 1,4,5 trisphosphate binding(GO:0070679)
0.4 3.8 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 3.3 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.4 2.6 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.4 2.5 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 2.4 GO:0051219 phosphoprotein binding(GO:0051219)
0.4 2.3 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 2.2 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 2.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.5 2.0 GO:0038025 reelin receptor activity(GO:0038025)
0.5 2.0 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.2 1.9 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 1.8 GO:0031072 heat shock protein binding(GO:0031072)
0.1 1.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 1.7 GO:0030742 GTP-dependent protein binding(GO:0030742)