Motif ID: Zbtb7b

Z-value: 0.919


Transcription factors associated with Zbtb7b:

Gene SymbolEntrez IDGene Name
Zbtb7b ENSMUSG00000028042.9 Zbtb7b

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zbtb7bmm10_v2_chr3_-_89393294_893933780.523.4e-06Click!


Activity profile for motif Zbtb7b.

activity profile for motif Zbtb7b


Sorted Z-values histogram for motif Zbtb7b

Sorted Z-values for motif Zbtb7b



Network of associatons between targets according to the STRING database.



First level regulatory network of Zbtb7b

PNG image of the network

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Top targets:


Showing 1 to 20 of 191 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_+_84756055 13.467 ENSMUST00000060397.6
 Rfx4
regulatory factor X, 4 (influences HLA class II expression)
chr8_-_105471481 11.640 ENSMUST00000014990.6
 Tppp3
tubulin polymerization-promoting protein family member 3
chr3_+_34649987 10.219 ENSMUST00000099151.2
 Sox2
SRY-box containing gene 2
chr1_-_119053339 9.929 ENSMUST00000161301.1
ENSMUST00000161451.1
ENSMUST00000162607.1
 Gli2


GLI-Kruppel family member GLI2


chr17_+_85620816 9.775 ENSMUST00000175898.2
 Six3
sine oculis-related homeobox 3
chr5_+_137350371 8.435 ENSMUST00000166239.1
ENSMUST00000111054.1
 Ephb4

Eph receptor B4

chr19_-_36736653 7.806 ENSMUST00000087321.2
 Ppp1r3c
protein phosphatase 1, regulatory (inhibitor) subunit 3C
chr11_+_120948480 6.934 ENSMUST00000070653.6
 Slc16a3
solute carrier family 16 (monocarboxylic acid transporters), member 3
chr15_-_32244632 6.689 ENSMUST00000181536.1
 0610007N19Rik
RIKEN cDNA 0610007N19
chr19_+_55742242 6.600 ENSMUST00000111652.1
ENSMUST00000111649.1
ENSMUST00000111651.1
ENSMUST00000111653.1
ENSMUST00000111656.1
ENSMUST00000127233.1
ENSMUST00000153888.1
 Tcf7l2






transcription factor 7 like 2, T cell specific, HMG box






chr12_+_53248677 6.410 ENSMUST00000101432.2
 Npas3
neuronal PAS domain protein 3
chr7_-_4752972 6.301 ENSMUST00000183971.1
ENSMUST00000182173.1
ENSMUST00000182738.1
ENSMUST00000184143.1
ENSMUST00000182111.1
ENSMUST00000182048.1
ENSMUST00000063324.7
 Cox6b2






cytochrome c oxidase subunit VIb polypeptide 2






chr7_+_51879041 6.276 ENSMUST00000107591.2
 Gas2
growth arrest specific 2
chr11_+_108920800 6.030 ENSMUST00000140821.1
 Axin2
axin2
chr7_+_51878967 5.994 ENSMUST00000051912.6
 Gas2
growth arrest specific 2
chr8_-_87959560 5.917 ENSMUST00000109655.2
 Zfp423
zinc finger protein 423
chr7_-_101837776 5.911 ENSMUST00000165052.1
 Inppl1
inositol polyphosphate phosphatase-like 1
chr6_-_134792596 5.285 ENSMUST00000100857.3
 Dusp16
dual specificity phosphatase 16
chr11_+_88068242 5.271 ENSMUST00000018521.4
 Vezf1
vascular endothelial zinc finger 1
chr7_-_126799163 5.211 ENSMUST00000032934.5
 Aldoa
aldolase A, fructose-bisphosphate

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 100 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.5 19.0 GO:0032252 secretory granule localization(GO:0032252)
2.7 13.5 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.1 12.3 GO:0008360 regulation of cell shape(GO:0008360)
3.0 11.9 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.2 11.6 GO:0046785 microtubule polymerization(GO:0046785)
1.5 10.2 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
1.0 10.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.5 10.2 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
2.5 9.9 GO:0060032 notochord regression(GO:0060032)
3.3 9.8 GO:0097402 neuroblast migration(GO:0097402)
1.0 8.6 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
2.1 8.4 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.5 8.1 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.6 6.4 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.5 6.4 GO:0042711 maternal behavior(GO:0042711)
0.8 5.9 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
1.5 5.8 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.0 5.5 GO:0007219 Notch signaling pathway(GO:0007219)
0.2 5.3 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.1 5.3 GO:0001885 endothelial cell development(GO:0001885)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 58 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 17.5 GO:0005667 transcription factor complex(GO:0005667)
0.5 11.9 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.7 10.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 10.2 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.8 9.9 GO:0097542 ciliary tip(GO:0097542)
0.2 8.9 GO:0005871 kinesin complex(GO:0005871)
0.6 8.6 GO:0043203 axon hillock(GO:0043203)
0.9 7.8 GO:0042587 glycogen granule(GO:0042587)
0.7 6.6 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.4 6.3 GO:0030061 mitochondrial crista(GO:0030061)
1.2 5.8 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 5.3 GO:0005901 caveola(GO:0005901)
0.2 4.9 GO:0051233 spindle midzone(GO:0051233)
0.7 4.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.3 4.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 3.8 GO:0030027 lamellipodium(GO:0030027)
0.5 3.5 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 3.4 GO:0034451 centriolar satellite(GO:0034451)
0.1 3.1 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 3.1 GO:0005581 collagen trimer(GO:0005581)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 79 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 35.2 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
1.1 12.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.6 11.9 GO:0070411 I-SMAD binding(GO:0070411)
1.7 10.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.6 10.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.5 10.2 GO:0035198 miRNA binding(GO:0035198)
0.5 9.8 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 8.9 GO:0003777 microtubule motor activity(GO:0003777)
0.1 8.7 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.2 8.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.4 8.4 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 8.3 GO:0046982 protein heterodimerization activity(GO:0046982)
0.1 7.4 GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982)
0.0 7.1 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.3 6.6 GO:0045295 gamma-catenin binding(GO:0045295)
0.3 6.3 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.6 5.9 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.1 5.7 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.5 5.3 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 5.1 GO:0001047 core promoter binding(GO:0001047)