Motif ID: Zfp148
Z-value: 1.176
Transcription factors associated with Zfp148:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Zfp148 | ENSMUSG00000022811.10 | Zfp148 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Zfp148 | mm10_v2_chr16_+_33380765_33380787 | 0.83 | 9.6e-19 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.2 | 36.2 | GO:0060666 | dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666) |
| 3.1 | 6.3 | GO:0021649 | vestibulocochlear nerve morphogenesis(GO:0021648) vestibulocochlear nerve structural organization(GO:0021649) cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) ganglion morphogenesis(GO:0061552) facioacoustic ganglion development(GO:1903375) dorsal root ganglion morphogenesis(GO:1904835) |
| 2.9 | 8.6 | GO:0016191 | synaptic vesicle uncoating(GO:0016191) regulation of endosome organization(GO:1904978) positive regulation of endosome organization(GO:1904980) |
| 2.3 | 7.0 | GO:0071677 | positive regulation of mononuclear cell migration(GO:0071677) |
| 2.1 | 8.3 | GO:1900740 | regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740) |
| 1.9 | 5.6 | GO:2000598 | regulation of cyclin catabolic process(GO:2000598) negative regulation of cyclin catabolic process(GO:2000599) |
| 1.7 | 1.7 | GO:0097491 | trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491) neural crest cell migration involved in autonomic nervous system development(GO:1901166) |
| 1.6 | 4.7 | GO:1904685 | positive regulation of metalloendopeptidase activity(GO:1904685) |
| 1.5 | 4.5 | GO:0032241 | positive regulation of nucleobase-containing compound transport(GO:0032241) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256) |
| 1.4 | 5.5 | GO:0097494 | positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944) regulation of vesicle size(GO:0097494) |
| 1.3 | 7.9 | GO:2000672 | negative regulation of motor neuron apoptotic process(GO:2000672) |
| 1.3 | 6.5 | GO:0060178 | regulation of exocyst localization(GO:0060178) |
| 1.3 | 6.3 | GO:2001025 | positive regulation of response to drug(GO:2001025) |
| 1.1 | 6.4 | GO:0010624 | regulation of Schwann cell proliferation(GO:0010624) |
| 1.0 | 3.1 | GO:0046098 | guanine metabolic process(GO:0046098) |
| 1.0 | 6.2 | GO:0045162 | clustering of voltage-gated sodium channels(GO:0045162) |
| 1.0 | 3.0 | GO:0072531 | pyrimidine-containing compound transmembrane transport(GO:0072531) |
| 1.0 | 8.1 | GO:0033601 | positive regulation of mammary gland epithelial cell proliferation(GO:0033601) |
| 0.9 | 6.4 | GO:0043553 | negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) |
| 0.9 | 10.8 | GO:0036376 | sodium ion export from cell(GO:0036376) |
| 0.9 | 3.6 | GO:0061428 | positive regulation of oocyte development(GO:0060282) negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428) |
| 0.9 | 9.5 | GO:0090084 | negative regulation of inclusion body assembly(GO:0090084) |
| 0.8 | 2.5 | GO:0019482 | beta-alanine metabolic process(GO:0019482) |
| 0.8 | 4.9 | GO:1902866 | regulation of retina development in camera-type eye(GO:1902866) |
| 0.8 | 8.7 | GO:0051103 | DNA ligation involved in DNA repair(GO:0051103) |
| 0.8 | 3.1 | GO:2000427 | positive regulation of apoptotic cell clearance(GO:2000427) |
| 0.7 | 3.3 | GO:0051012 | microtubule sliding(GO:0051012) negative regulation of nonmotile primary cilium assembly(GO:1902856) |
| 0.7 | 2.0 | GO:1903061 | regulation of protein lipidation(GO:1903059) positive regulation of protein lipidation(GO:1903061) |
| 0.7 | 20.8 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
| 0.6 | 1.9 | GO:0036091 | positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091) |
| 0.6 | 5.7 | GO:0018095 | protein polyglutamylation(GO:0018095) |
| 0.6 | 5.6 | GO:0036371 | T-tubule organization(GO:0033292) protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) |
| 0.6 | 26.7 | GO:0035640 | exploration behavior(GO:0035640) |
| 0.6 | 2.9 | GO:0070327 | thyroid hormone transport(GO:0070327) |
| 0.6 | 1.1 | GO:0002182 | cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248) |
| 0.5 | 2.7 | GO:0032226 | positive regulation of synaptic transmission, dopaminergic(GO:0032226) |
| 0.5 | 3.1 | GO:1900246 | positive regulation of RIG-I signaling pathway(GO:1900246) |
| 0.5 | 2.1 | GO:0035434 | copper ion transmembrane transport(GO:0035434) |
| 0.5 | 5.5 | GO:0023041 | neuronal signal transduction(GO:0023041) |
| 0.5 | 4.9 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
| 0.5 | 2.4 | GO:0001927 | exocyst assembly(GO:0001927) |
| 0.5 | 6.8 | GO:1990403 | embryonic brain development(GO:1990403) |
| 0.5 | 2.4 | GO:0010991 | regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991) |
| 0.5 | 1.4 | GO:0045085 | negative regulation of interleukin-2 biosynthetic process(GO:0045085) |
| 0.5 | 4.7 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
| 0.5 | 4.2 | GO:0097421 | liver regeneration(GO:0097421) |
| 0.5 | 1.8 | GO:0035521 | monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522) |
| 0.4 | 3.9 | GO:0090166 | Golgi disassembly(GO:0090166) |
| 0.4 | 1.8 | GO:0014022 | neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) |
| 0.4 | 6.8 | GO:0061157 | mRNA destabilization(GO:0061157) |
| 0.3 | 4.4 | GO:1990126 | retrograde transport, endosome to plasma membrane(GO:1990126) |
| 0.3 | 8.0 | GO:0095500 | acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145) |
| 0.3 | 8.3 | GO:0048488 | synaptic vesicle endocytosis(GO:0048488) |
| 0.3 | 24.0 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
| 0.3 | 1.1 | GO:0002035 | brain renin-angiotensin system(GO:0002035) |
| 0.3 | 2.0 | GO:1900194 | negative regulation of oocyte maturation(GO:1900194) |
| 0.3 | 3.0 | GO:0007252 | I-kappaB phosphorylation(GO:0007252) |
| 0.3 | 1.1 | GO:1903898 | positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) negative regulation of PERK-mediated unfolded protein response(GO:1903898) |
| 0.3 | 2.6 | GO:0030049 | muscle filament sliding(GO:0030049) |
| 0.2 | 1.2 | GO:0071476 | cellular hypotonic response(GO:0071476) |
| 0.2 | 3.9 | GO:0090161 | Golgi ribbon formation(GO:0090161) |
| 0.2 | 1.1 | GO:0071787 | endoplasmic reticulum tubular network assembly(GO:0071787) |
| 0.2 | 2.0 | GO:1901660 | calcium ion export(GO:1901660) |
| 0.2 | 5.5 | GO:0016578 | histone deubiquitination(GO:0016578) |
| 0.2 | 0.8 | GO:1904425 | negative regulation of GTP binding(GO:1904425) |
| 0.2 | 2.2 | GO:0033008 | positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306) |
| 0.2 | 0.6 | GO:0061153 | trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) |
| 0.2 | 3.1 | GO:0071625 | vocalization behavior(GO:0071625) |
| 0.2 | 2.5 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
| 0.2 | 0.5 | GO:0036353 | histone H2A-K119 monoubiquitination(GO:0036353) |
| 0.2 | 1.6 | GO:0046543 | development of secondary female sexual characteristics(GO:0046543) |
| 0.2 | 1.6 | GO:0033169 | histone H3-K9 demethylation(GO:0033169) |
| 0.2 | 3.3 | GO:0006415 | translational termination(GO:0006415) |
| 0.2 | 8.2 | GO:0021696 | cerebellar cortex morphogenesis(GO:0021696) |
| 0.2 | 0.5 | GO:0009446 | putrescine biosynthetic process(GO:0009446) |
| 0.2 | 1.9 | GO:1901339 | regulation of store-operated calcium channel activity(GO:1901339) |
| 0.2 | 1.8 | GO:0045634 | regulation of melanocyte differentiation(GO:0045634) |
| 0.2 | 0.8 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) |
| 0.2 | 4.4 | GO:0006904 | vesicle docking involved in exocytosis(GO:0006904) |
| 0.1 | 0.4 | GO:0033092 | positive regulation of immature T cell proliferation in thymus(GO:0033092) |
| 0.1 | 2.1 | GO:0036065 | fucosylation(GO:0036065) |
| 0.1 | 3.9 | GO:0031116 | positive regulation of microtubule polymerization(GO:0031116) |
| 0.1 | 1.3 | GO:0042403 | thyroid hormone metabolic process(GO:0042403) |
| 0.1 | 4.7 | GO:0048843 | negative regulation of axon extension involved in axon guidance(GO:0048843) |
| 0.1 | 0.3 | GO:0097107 | postsynaptic density organization(GO:0097106) postsynaptic density assembly(GO:0097107) |
| 0.1 | 1.4 | GO:0007183 | SMAD protein complex assembly(GO:0007183) |
| 0.1 | 0.9 | GO:0060019 | radial glial cell differentiation(GO:0060019) |
| 0.1 | 1.1 | GO:0019227 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
| 0.1 | 3.9 | GO:0051926 | negative regulation of calcium ion transport(GO:0051926) |
| 0.1 | 5.5 | GO:0019915 | lipid storage(GO:0019915) |
| 0.1 | 0.2 | GO:0007181 | epicardial cell to mesenchymal cell transition(GO:0003347) transforming growth factor beta receptor complex assembly(GO:0007181) |
| 0.1 | 1.6 | GO:0016973 | poly(A)+ mRNA export from nucleus(GO:0016973) |
| 0.1 | 1.2 | GO:0007220 | Notch receptor processing(GO:0007220) |
| 0.1 | 14.3 | GO:0071804 | cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805) |
| 0.1 | 2.5 | GO:0006491 | N-glycan processing(GO:0006491) |
| 0.1 | 4.7 | GO:0045599 | negative regulation of fat cell differentiation(GO:0045599) |
| 0.1 | 0.8 | GO:0035092 | sperm chromatin condensation(GO:0035092) |
| 0.1 | 0.3 | GO:0071879 | regulation of adrenergic receptor signaling pathway(GO:0071877) positive regulation of adrenergic receptor signaling pathway(GO:0071879) |
| 0.1 | 6.7 | GO:0003281 | ventricular septum development(GO:0003281) |
| 0.1 | 0.7 | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) |
| 0.1 | 0.8 | GO:1902857 | positive regulation of nonmotile primary cilium assembly(GO:1902857) |
| 0.1 | 0.7 | GO:0090050 | positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) |
| 0.1 | 0.6 | GO:0060346 | bone trabecula formation(GO:0060346) |
| 0.1 | 1.5 | GO:0042753 | positive regulation of circadian rhythm(GO:0042753) |
| 0.1 | 3.7 | GO:0046579 | positive regulation of Ras protein signal transduction(GO:0046579) |
| 0.1 | 0.6 | GO:0030836 | positive regulation of actin filament depolymerization(GO:0030836) |
| 0.1 | 3.3 | GO:0032411 | positive regulation of transporter activity(GO:0032411) |
| 0.1 | 0.5 | GO:0005981 | regulation of glycogen catabolic process(GO:0005981) |
| 0.1 | 3.3 | GO:0042632 | cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092) |
| 0.1 | 2.8 | GO:0051693 | actin filament capping(GO:0051693) |
| 0.1 | 0.9 | GO:0021819 | layer formation in cerebral cortex(GO:0021819) radial glia guided migration of Purkinje cell(GO:0021942) |
| 0.1 | 0.9 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 0.1 | 3.6 | GO:0010507 | negative regulation of autophagy(GO:0010507) |
| 0.1 | 0.8 | GO:0000076 | DNA replication checkpoint(GO:0000076) |
| 0.1 | 1.5 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
| 0.1 | 7.6 | GO:0000423 | macromitophagy(GO:0000423) mitophagy in response to mitochondrial depolarization(GO:0098779) response to mitochondrial depolarisation(GO:0098780) |
| 0.1 | 1.6 | GO:0045104 | intermediate filament cytoskeleton organization(GO:0045104) |
| 0.1 | 0.5 | GO:0070102 | interleukin-6-mediated signaling pathway(GO:0070102) |
| 0.1 | 0.9 | GO:2000311 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311) |
| 0.0 | 0.5 | GO:0097034 | mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034) |
| 0.0 | 0.1 | GO:0030070 | insulin processing(GO:0030070) |
| 0.0 | 2.1 | GO:0045670 | regulation of osteoclast differentiation(GO:0045670) |
| 0.0 | 1.2 | GO:1903146 | regulation of mitophagy(GO:1903146) |
| 0.0 | 1.3 | GO:0048745 | smooth muscle tissue development(GO:0048745) |
| 0.0 | 1.1 | GO:0045494 | photoreceptor cell maintenance(GO:0045494) |
| 0.0 | 1.2 | GO:0007131 | reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825) |
| 0.0 | 4.3 | GO:0007612 | learning(GO:0007612) |
| 0.0 | 1.9 | GO:0008543 | fibroblast growth factor receptor signaling pathway(GO:0008543) |
| 0.0 | 0.9 | GO:0051569 | regulation of histone H3-K4 methylation(GO:0051569) |
| 0.0 | 5.6 | GO:0042787 | protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787) |
| 0.0 | 5.8 | GO:0060070 | canonical Wnt signaling pathway(GO:0060070) |
| 0.0 | 0.5 | GO:1900745 | positive regulation of p38MAPK cascade(GO:1900745) |
| 0.0 | 1.0 | GO:0018208 | peptidyl-proline modification(GO:0018208) |
| 0.0 | 2.0 | GO:0030593 | neutrophil chemotaxis(GO:0030593) |
| 0.0 | 4.7 | GO:0007411 | axon guidance(GO:0007411) |
| 0.0 | 0.6 | GO:0000186 | activation of MAPKK activity(GO:0000186) |
| 0.0 | 0.6 | GO:0034198 | cellular response to amino acid starvation(GO:0034198) |
| 0.0 | 3.2 | GO:0050890 | cognition(GO:0050890) |
| 0.0 | 2.6 | GO:0051297 | centrosome organization(GO:0051297) |
| 0.0 | 3.2 | GO:0010977 | negative regulation of neuron projection development(GO:0010977) |
| 0.0 | 0.3 | GO:0034063 | stress granule assembly(GO:0034063) |
| 0.0 | 0.1 | GO:0048672 | positive regulation of collateral sprouting(GO:0048672) |
| 0.0 | 0.1 | GO:0015910 | peroxisomal long-chain fatty acid import(GO:0015910) |
| 0.0 | 3.8 | GO:0042384 | cilium assembly(GO:0042384) |
| 0.0 | 2.6 | GO:0035304 | regulation of protein dephosphorylation(GO:0035304) |
| 0.0 | 1.4 | GO:0031532 | actin cytoskeleton reorganization(GO:0031532) |
| 0.0 | 0.8 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 0.0 | 1.6 | GO:0007160 | cell-matrix adhesion(GO:0007160) |
| 0.0 | 0.8 | GO:0043473 | pigmentation(GO:0043473) |
| 0.0 | 1.5 | GO:0000209 | protein polyubiquitination(GO:0000209) |
| 0.0 | 0.4 | GO:0006360 | transcription from RNA polymerase I promoter(GO:0006360) |
| 0.0 | 0.1 | GO:0031663 | lipopolysaccharide-mediated signaling pathway(GO:0031663) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.8 | 2.8 | GO:0032437 | cuticular plate(GO:0032437) |
| 2.6 | 7.9 | GO:0097058 | CRLF-CLCF1 complex(GO:0097058) |
| 2.1 | 8.3 | GO:0070032 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) |
| 1.6 | 6.4 | GO:0097450 | astrocyte end-foot(GO:0097450) |
| 1.5 | 10.8 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) dendritic spine neck(GO:0044326) |
| 1.5 | 8.7 | GO:0043564 | Ku70:Ku80 complex(GO:0043564) |
| 1.0 | 6.2 | GO:0008091 | spectrin(GO:0008091) |
| 0.8 | 6.8 | GO:0000813 | ESCRT I complex(GO:0000813) |
| 0.6 | 8.2 | GO:0005719 | nuclear euchromatin(GO:0005719) |
| 0.6 | 3.6 | GO:0033010 | paranodal junction(GO:0033010) |
| 0.6 | 7.1 | GO:0000124 | SAGA complex(GO:0000124) |
| 0.6 | 3.4 | GO:1990635 | proximal dendrite(GO:1990635) |
| 0.4 | 2.0 | GO:0032591 | dendritic spine membrane(GO:0032591) |
| 0.4 | 3.0 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.4 | 1.1 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
| 0.4 | 6.5 | GO:0000145 | exocyst(GO:0000145) |
| 0.3 | 8.6 | GO:0030132 | clathrin coat of coated pit(GO:0030132) |
| 0.3 | 2.7 | GO:0031254 | uropod(GO:0001931) cell trailing edge(GO:0031254) |
| 0.3 | 37.6 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.3 | 0.8 | GO:0005940 | septin ring(GO:0005940) |
| 0.3 | 1.4 | GO:0000120 | RNA polymerase I transcription factor complex(GO:0000120) |
| 0.3 | 1.6 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
| 0.3 | 5.6 | GO:0031430 | M band(GO:0031430) |
| 0.2 | 10.6 | GO:0030118 | clathrin coat(GO:0030118) |
| 0.2 | 4.5 | GO:0032279 | asymmetric synapse(GO:0032279) |
| 0.2 | 2.0 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.2 | 3.8 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
| 0.2 | 3.0 | GO:0097539 | ciliary transition fiber(GO:0097539) |
| 0.2 | 0.8 | GO:0031084 | BLOC-2 complex(GO:0031084) |
| 0.2 | 2.6 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
| 0.2 | 1.7 | GO:0000439 | core TFIIH complex(GO:0000439) |
| 0.2 | 6.8 | GO:0035869 | ciliary transition zone(GO:0035869) |
| 0.2 | 6.2 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
| 0.2 | 1.8 | GO:1990909 | Wnt signalosome(GO:1990909) |
| 0.2 | 1.6 | GO:0045095 | keratin filament(GO:0045095) |
| 0.2 | 2.9 | GO:0071004 | U2-type prespliceosome(GO:0071004) |
| 0.1 | 9.7 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.1 | 3.5 | GO:0001891 | phagocytic cup(GO:0001891) |
| 0.1 | 6.9 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.1 | 0.8 | GO:0030896 | checkpoint clamp complex(GO:0030896) |
| 0.1 | 35.4 | GO:0045211 | postsynaptic membrane(GO:0045211) |
| 0.1 | 22.7 | GO:0070382 | exocytic vesicle(GO:0070382) |
| 0.1 | 2.5 | GO:0005903 | brush border(GO:0005903) |
| 0.1 | 3.6 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.1 | 1.9 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
| 0.1 | 4.1 | GO:0031201 | SNARE complex(GO:0031201) |
| 0.1 | 1.1 | GO:0072546 | ER membrane protein complex(GO:0072546) |
| 0.1 | 0.6 | GO:0016461 | unconventional myosin complex(GO:0016461) |
| 0.1 | 2.0 | GO:0070822 | Sin3-type complex(GO:0070822) |
| 0.1 | 1.9 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.1 | 1.8 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.1 | 1.1 | GO:0001917 | photoreceptor inner segment(GO:0001917) |
| 0.1 | 0.2 | GO:0034673 | inhibin-betaglycan-ActRII complex(GO:0034673) |
| 0.1 | 0.5 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
| 0.1 | 37.9 | GO:0030425 | dendrite(GO:0030425) |
| 0.1 | 1.1 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.1 | 0.6 | GO:0061700 | GATOR2 complex(GO:0061700) |
| 0.1 | 0.2 | GO:0035032 | phosphatidylinositol 3-kinase complex, class III(GO:0035032) |
| 0.0 | 2.7 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.0 | 0.7 | GO:0042405 | nuclear inclusion body(GO:0042405) |
| 0.0 | 3.3 | GO:0005930 | axoneme(GO:0005930) ciliary plasm(GO:0097014) |
| 0.0 | 2.6 | GO:0036064 | ciliary basal body(GO:0036064) |
| 0.0 | 3.2 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.0 | 4.8 | GO:0005770 | late endosome(GO:0005770) |
| 0.0 | 3.9 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
| 0.0 | 0.3 | GO:0001739 | sex chromatin(GO:0001739) |
| 0.0 | 0.3 | GO:0005677 | chromatin silencing complex(GO:0005677) |
| 0.0 | 5.6 | GO:0030424 | axon(GO:0030424) |
| 0.0 | 7.9 | GO:0045202 | synapse(GO:0045202) |
| 0.0 | 0.5 | GO:0031305 | integral component of mitochondrial inner membrane(GO:0031305) |
| 0.0 | 1.2 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.0 | 0.3 | GO:0030904 | retromer complex(GO:0030904) |
| 0.0 | 8.2 | GO:0005740 | mitochondrial envelope(GO:0005740) |
| 0.0 | 1.0 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.0 | 0.4 | GO:0030133 | transport vesicle(GO:0030133) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.3 | 36.7 | GO:0038191 | neuropilin binding(GO:0038191) |
| 2.1 | 6.4 | GO:0036313 | phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313) |
| 1.9 | 15.6 | GO:0030550 | acetylcholine receptor inhibitor activity(GO:0030550) |
| 1.3 | 10.8 | GO:0103116 | alpha-D-galactofuranose transporter activity(GO:0103116) |
| 1.2 | 8.6 | GO:0004439 | phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439) |
| 1.2 | 10.7 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
| 1.1 | 7.9 | GO:0005127 | ciliary neurotrophic factor receptor binding(GO:0005127) |
| 1.0 | 3.1 | GO:0030226 | apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) |
| 0.9 | 6.3 | GO:0005021 | vascular endothelial growth factor-activated receptor activity(GO:0005021) |
| 0.9 | 3.6 | GO:0034739 | histone deacetylase activity (H4-K16 specific)(GO:0034739) tubulin deacetylase activity(GO:0042903) |
| 0.8 | 3.3 | GO:0016149 | translation release factor activity, codon specific(GO:0016149) |
| 0.8 | 5.7 | GO:0031821 | G-protein coupled serotonin receptor binding(GO:0031821) |
| 0.8 | 7.7 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
| 0.7 | 2.9 | GO:0015349 | thyroid hormone transmembrane transporter activity(GO:0015349) |
| 0.7 | 4.2 | GO:0046976 | histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
| 0.7 | 8.1 | GO:0035014 | phosphatidylinositol 3-kinase regulator activity(GO:0035014) |
| 0.7 | 2.6 | GO:0030160 | GKAP/Homer scaffold activity(GO:0030160) |
| 0.6 | 4.5 | GO:0032795 | G-protein coupled adenosine receptor activity(GO:0001609) heterotrimeric G-protein binding(GO:0032795) |
| 0.6 | 3.0 | GO:0008559 | xenobiotic-transporting ATPase activity(GO:0008559) |
| 0.6 | 7.9 | GO:0030955 | potassium ion binding(GO:0030955) |
| 0.5 | 4.7 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
| 0.5 | 2.5 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
| 0.5 | 2.5 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
| 0.4 | 4.7 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
| 0.4 | 1.6 | GO:1990254 | keratin filament binding(GO:1990254) |
| 0.4 | 2.0 | GO:0016941 | natriuretic peptide receptor activity(GO:0016941) |
| 0.3 | 8.3 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.3 | 12.5 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.3 | 4.1 | GO:0070300 | phosphatidic acid binding(GO:0070300) |
| 0.3 | 1.3 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 0.3 | 0.8 | GO:0050510 | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510) |
| 0.3 | 14.6 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.3 | 2.0 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
| 0.2 | 5.5 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.2 | 1.9 | GO:0005168 | neurotrophin TRKA receptor binding(GO:0005168) |
| 0.2 | 10.2 | GO:0018602 | sulfonate dioxygenase activity(GO:0000907) 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity(GO:0018602) hypophosphite dioxygenase activity(GO:0034792) gibberellin 2-beta-dioxygenase activity(GO:0045543) C-19 gibberellin 2-beta-dioxygenase activity(GO:0052634) C-20 gibberellin 2-beta-dioxygenase activity(GO:0052635) |
| 0.2 | 3.3 | GO:0017128 | phospholipid scramblase activity(GO:0017128) |
| 0.2 | 0.9 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
| 0.2 | 6.0 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.2 | 1.8 | GO:0016920 | pyroglutamyl-peptidase activity(GO:0016920) |
| 0.2 | 3.1 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
| 0.2 | 2.0 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.2 | 1.0 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.2 | 5.3 | GO:0017147 | Wnt-protein binding(GO:0017147) |
| 0.2 | 4.6 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
| 0.2 | 5.0 | GO:0004407 | histone deacetylase activity(GO:0004407) |
| 0.2 | 20.2 | GO:0002020 | protease binding(GO:0002020) |
| 0.2 | 2.1 | GO:0005375 | copper ion transmembrane transporter activity(GO:0005375) |
| 0.2 | 1.7 | GO:0034943 | acyl-CoA ligase activity(GO:0003996) 3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity(GO:0010435) 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity(GO:0018854) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity(GO:0018855) benzoyl acetate-CoA ligase activity(GO:0018856) 2,4-dichlorobenzoate-CoA ligase activity(GO:0018857) very long-chain fatty acid-CoA ligase activity(GO:0031957) pivalate-CoA ligase activity(GO:0034783) cyclopropanecarboxylate-CoA ligase activity(GO:0034793) adipate-CoA ligase activity(GO:0034796) citronellyl-CoA ligase activity(GO:0034823) mentha-1,3-dione-CoA ligase activity(GO:0034841) thiophene-2-carboxylate-CoA ligase activity(GO:0034842) 2,4,4-trimethylpentanoate-CoA ligase activity(GO:0034865) cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034942) trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034943) branched-chain acyl-CoA synthetase (ADP-forming) activity(GO:0043759) aryl-CoA synthetase (ADP-forming) activity(GO:0043762) 3-hydroxypropionyl-CoA synthetase activity(GO:0043955) perillic acid:CoA ligase (ADP-forming) activity(GO:0052685) perillic acid:CoA ligase (AMP-forming) activity(GO:0052686) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity(GO:0052687) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity(GO:0052688) pristanate-CoA ligase activity(GO:0070251) malonyl-CoA synthetase activity(GO:0090409) |
| 0.1 | 14.1 | GO:0016810 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810) |
| 0.1 | 4.2 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.1 | 2.6 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.1 | 6.0 | GO:0030276 | clathrin binding(GO:0030276) |
| 0.1 | 2.6 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 0.1 | 1.1 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
| 0.1 | 1.2 | GO:0042500 | aspartic endopeptidase activity, intramembrane cleaving(GO:0042500) |
| 0.1 | 2.0 | GO:0042805 | actinin binding(GO:0042805) |
| 0.1 | 9.2 | GO:0051082 | unfolded protein binding(GO:0051082) |
| 0.1 | 0.2 | GO:0004675 | transmembrane receptor protein serine/threonine kinase activity(GO:0004675) transforming growth factor beta-activated receptor activity(GO:0005024) |
| 0.1 | 2.5 | GO:0004029 | aldehyde dehydrogenase (NAD) activity(GO:0004029) |
| 0.1 | 4.1 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.1 | 9.7 | GO:0051117 | ATPase binding(GO:0051117) |
| 0.1 | 0.5 | GO:0042979 | ornithine decarboxylase regulator activity(GO:0042979) |
| 0.1 | 1.7 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
| 0.1 | 1.1 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.1 | 6.1 | GO:0003730 | mRNA 3'-UTR binding(GO:0003730) |
| 0.1 | 5.5 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
| 0.1 | 5.9 | GO:0017048 | Rho GTPase binding(GO:0017048) |
| 0.1 | 2.9 | GO:0019905 | syntaxin binding(GO:0019905) |
| 0.1 | 0.2 | GO:0001565 | phorbol ester receptor activity(GO:0001565) non-kinase phorbol ester receptor activity(GO:0001566) |
| 0.1 | 0.5 | GO:0071535 | RING-like zinc finger domain binding(GO:0071535) |
| 0.1 | 4.5 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
| 0.1 | 0.6 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
| 0.1 | 1.1 | GO:0004711 | ribosomal protein S6 kinase activity(GO:0004711) |
| 0.1 | 2.6 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.1 | 2.1 | GO:0001221 | transcription cofactor binding(GO:0001221) |
| 0.1 | 1.1 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.1 | 6.4 | GO:0019210 | protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210) |
| 0.1 | 1.2 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.1 | 2.1 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 0.1 | 1.6 | GO:0070412 | R-SMAD binding(GO:0070412) |
| 0.1 | 1.8 | GO:0001540 | beta-amyloid binding(GO:0001540) |
| 0.1 | 6.0 | GO:0004702 | receptor signaling protein serine/threonine kinase activity(GO:0004702) |
| 0.1 | 1.8 | GO:0015459 | potassium channel regulator activity(GO:0015459) |
| 0.1 | 12.7 | GO:0030695 | GTPase regulator activity(GO:0030695) |
| 0.0 | 0.3 | GO:0051959 | dynein light intermediate chain binding(GO:0051959) |
| 0.0 | 2.9 | GO:0004583 | dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583) |
| 0.0 | 6.2 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 0.0 | 2.0 | GO:0004896 | cytokine receptor activity(GO:0004896) |
| 0.0 | 2.7 | GO:0005080 | protein kinase C binding(GO:0005080) |
| 0.0 | 0.1 | GO:0019002 | GMP binding(GO:0019002) |
| 0.0 | 0.4 | GO:0097027 | ubiquitin-protein transferase activator activity(GO:0097027) |
| 0.0 | 0.3 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
| 0.0 | 0.4 | GO:0001163 | RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164) |
| 0.0 | 3.1 | GO:0017124 | SH3 domain binding(GO:0017124) |
| 0.0 | 2.6 | GO:0101005 | thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005) |
| 0.0 | 0.9 | GO:0005245 | voltage-gated calcium channel activity(GO:0005245) |
| 0.0 | 1.2 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
| 0.0 | 0.5 | GO:0017160 | Ral GTPase binding(GO:0017160) |
| 0.0 | 0.6 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.0 | 1.1 | GO:0043022 | ribosome binding(GO:0043022) |
| 0.0 | 0.2 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
| 0.0 | 2.7 | GO:0005088 | Ras guanyl-nucleotide exchange factor activity(GO:0005088) |
| 0.0 | 0.4 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.0 | 1.9 | GO:0001948 | glycoprotein binding(GO:0001948) |
| 0.0 | 1.1 | GO:0008083 | growth factor activity(GO:0008083) |
| 0.0 | 1.8 | GO:0005125 | cytokine activity(GO:0005125) |
| 0.0 | 0.1 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
| 0.0 | 1.7 | GO:0030165 | PDZ domain binding(GO:0030165) |
| 0.0 | 1.6 | GO:0047485 | protein N-terminus binding(GO:0047485) |
| 0.0 | 0.3 | GO:0008143 | poly(A) binding(GO:0008143) |
| 0.0 | 1.1 | GO:0032947 | protein complex scaffold(GO:0032947) |
| 0.0 | 0.8 | GO:0008186 | ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186) |
