Motif ID: Zfp219_Zfp740

Z-value: 1.016

Transcription factors associated with Zfp219_Zfp740:

Gene SymbolEntrez IDGene Name
Zfp219 ENSMUSG00000049295.10 Zfp219
Zfp740 ENSMUSG00000046897.10 Zfp740

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp740mm10_v2_chr15_+_102203639_1022037090.291.6e-02Click!
Zfp219mm10_v2_chr14_-_52020698_520207370.263.2e-02Click!


Activity profile for motif Zfp219_Zfp740.

activity profile for motif Zfp219_Zfp740


Sorted Z-values histogram for motif Zfp219_Zfp740

Sorted Z-values for motif Zfp219_Zfp740



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp219_Zfp740

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_-_127341583 4.509 ENSMUST00000026474.3
 Gli1
GLI-Kruppel family member GLI1
chr15_+_57694651 4.317 ENSMUST00000096430.4
 Zhx2
zinc fingers and homeoboxes 2
chr19_-_59170978 4.148 ENSMUST00000172821.2
 Vax1
ventral anterior homeobox containing gene 1
chr13_-_29984219 3.802 ENSMUST00000146092.1
 E2f3
E2F transcription factor 3
chr5_-_134747241 3.779 ENSMUST00000015138.9
 Eln
elastin
chr7_+_127777095 3.582 ENSMUST00000144406.1
 Setd1a
SET domain containing 1A
chr2_+_48949495 3.318 ENSMUST00000112745.1
 Mbd5
methyl-CpG binding domain protein 5
chr10_-_127620922 3.256 ENSMUST00000118455.1
 Lrp1
low density lipoprotein receptor-related protein 1
chr16_+_43503607 3.218 ENSMUST00000126100.1
ENSMUST00000123047.1
ENSMUST00000156981.1
 Zbtb20


zinc finger and BTB domain containing 20


chr2_-_36105271 3.202 ENSMUST00000112960.1
ENSMUST00000112967.5
ENSMUST00000112963.1
 Lhx6


LIM homeobox protein 6


chr12_-_27342696 3.183 ENSMUST00000079063.5
 Sox11
SRY-box containing gene 11
chr7_+_127511976 3.161 ENSMUST00000098025.4
 Srcap
Snf2-related CREBBP activator protein
chr7_-_78577771 2.962 ENSMUST00000039438.7
 Ntrk3
neurotrophic tyrosine kinase, receptor, type 3
chr7_-_78578308 2.825 ENSMUST00000039431.7
 Ntrk3
neurotrophic tyrosine kinase, receptor, type 3
chr2_-_116065798 2.798 ENSMUST00000110907.1
ENSMUST00000110908.2
 Meis2

Meis homeobox 2

chr2_-_180225812 2.758 ENSMUST00000015791.5
 Lama5
laminin, alpha 5
chr16_+_44173271 2.592 ENSMUST00000088356.4
ENSMUST00000169582.1
 Gm608

predicted gene 608

chr1_-_56972437 2.575 ENSMUST00000042857.7
 Satb2
special AT-rich sequence binding protein 2
chr10_-_127620960 2.535 ENSMUST00000121829.1
 Lrp1
low density lipoprotein receptor-related protein 1
chrX_-_94123087 2.466 ENSMUST00000113925.1
 Zfx
zinc finger protein X-linked

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 219 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.2 6.1 GO:2000587 regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
1.9 5.8 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.0 5.8 GO:0006333 chromatin assembly or disassembly(GO:0006333)
0.1 5.6 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.4 5.3 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.6 4.6 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
1.1 4.5 GO:0003357 noradrenergic neuron differentiation(GO:0003357)
1.1 4.5 GO:0060032 notochord regression(GO:0060032)
1.0 4.2 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.3 4.0 GO:1990403 embryonic brain development(GO:1990403)
0.7 3.9 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.8 3.8 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.2 3.6 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.2 3.5 GO:0030325 adrenal gland development(GO:0030325)
1.1 3.3 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
1.1 3.3 GO:1904049 regulation of spontaneous neurotransmitter secretion(GO:1904048) negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.5 3.2 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.2 3.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 3.2 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 3.1 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 93 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 14.3 GO:0005667 transcription factor complex(GO:0005667)
0.1 7.3 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 6.3 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 5.3 GO:0000785 chromatin(GO:0000785)
0.3 4.5 GO:0097542 ciliary tip(GO:0097542)
0.4 4.4 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 4.3 GO:0005844 polysome(GO:0005844)
0.1 4.0 GO:0035869 ciliary transition zone(GO:0035869)
0.2 3.9 GO:0010369 chromocenter(GO:0010369)
1.3 3.8 GO:0071953 elastic fiber(GO:0071953)
0.7 3.3 GO:1990761 growth cone lamellipodium(GO:1990761)
0.0 3.3 GO:0005925 focal adhesion(GO:0005925)
0.1 3.2 GO:0009925 basal plasma membrane(GO:0009925)
0.6 3.0 GO:0044666 MLL3/4 complex(GO:0044666)
0.7 2.8 GO:0043259 laminin-10 complex(GO:0043259)
0.1 2.6 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.2 2.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 2.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 2.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.7 2.2 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 138 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 20.0 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 11.5 GO:0000987 core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.1 8.3 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 8.2 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.2 7.3 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.3 5.9 GO:0034185 apolipoprotein binding(GO:0034185)
1.2 5.8 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.3 5.7 GO:0008266 poly(U) RNA binding(GO:0008266)
0.3 5.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.6 4.4 GO:1990188 euchromatin binding(GO:1990188)
0.5 4.2 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.2 4.2 GO:0005003 ephrin receptor activity(GO:0005003)
0.8 4.1 GO:0001093 TFIIB-class transcription factor binding(GO:0001093)
0.0 3.5 GO:0046332 SMAD binding(GO:0046332)
0.1 3.4 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 3.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 2.7 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.4 2.6 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 2.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 2.3 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)