Motif ID: Zfp423

Z-value: 0.498


Transcription factors associated with Zfp423:

Gene SymbolEntrez IDGene Name
Zfp423 ENSMUSG00000045333.9 Zfp423

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp423mm10_v2_chr8_-_87959560_87959595-0.319.4e-03Click!


Activity profile for motif Zfp423.

activity profile for motif Zfp423


Sorted Z-values histogram for motif Zfp423

Sorted Z-values for motif Zfp423



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp423

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Showing 1 to 20 of 72 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_180499893 6.369 ENSMUST00000029084.2
Ntsr1
neurotensin receptor 1
chr4_+_42917234 4.616 ENSMUST00000107976.2
ENSMUST00000069184.2
N28178

expressed sequence N28178

chr14_+_119138415 4.147 ENSMUST00000065904.3
Hs6st3
heparan sulfate 6-O-sulfotransferase 3
chr5_-_22344690 4.053 ENSMUST00000062372.7
ENSMUST00000161356.1
Reln

reelin

chr2_-_29253001 3.853 ENSMUST00000071201.4
Ntng2
netrin G2
chr10_+_13966268 3.411 ENSMUST00000015645.4
Hivep2
human immunodeficiency virus type I enhancer binding protein 2
chr7_+_29307924 3.002 ENSMUST00000108230.1
ENSMUST00000065181.5
Dpf1

D4, zinc and double PHD fingers family 1

chr15_-_66286224 2.577 ENSMUST00000070256.7
Kcnq3
potassium voltage-gated channel, subfamily Q, member 3
chrX_+_7822289 2.542 ENSMUST00000009875.4
Kcnd1
potassium voltage-gated channel, Shal-related family, member 1
chr14_+_70553687 2.534 ENSMUST00000161069.1
Hr
hairless
chr10_-_62110945 2.486 ENSMUST00000142821.1
ENSMUST00000124615.1
ENSMUST00000064050.4
ENSMUST00000125704.1
ENSMUST00000142796.1
2010107G23Rik




RIKEN cDNA 2010107G23 gene




chr19_+_6401675 2.350 ENSMUST00000113471.1
ENSMUST00000113469.2
Rasgrp2

RAS, guanyl releasing protein 2

chr6_+_110645572 2.298 ENSMUST00000071076.6
ENSMUST00000172951.1
Grm7

glutamate receptor, metabotropic 7

chr12_+_102948843 2.292 ENSMUST00000101099.5
Unc79
unc-79 homolog (C. elegans)
chr5_-_135934590 2.174 ENSMUST00000055808.5
Ywhag
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
chr7_-_105633525 2.137 ENSMUST00000153371.1
ENSMUST00000106789.1
ENSMUST00000057525.7
Trim3


tripartite motif-containing 3


chr15_-_78718113 1.979 ENSMUST00000088592.4
Elfn2
leucine rich repeat and fibronectin type III, extracellular 2
chr7_-_105633479 1.898 ENSMUST00000147044.1
ENSMUST00000106791.1
Trim3

tripartite motif-containing 3

chr12_-_14152038 1.802 ENSMUST00000020926.6
Fam84a
family with sequence similarity 84, member A
chr19_-_10869757 1.687 ENSMUST00000120524.1
ENSMUST00000025645.7
Tmem132a

transmembrane protein 132A


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 32 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.6 6.4 GO:1903802 positive regulation of arachidonic acid secretion(GO:0090238) L-glutamate(1-) import into cell(GO:1903802) L-glutamate import into cell(GO:1990123)
1.0 4.1 GO:0097477 lateral motor column neuron migration(GO:0097477)
0.7 4.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.2 2.6 GO:0060081 membrane hyperpolarization(GO:0060081)
0.0 2.5 GO:0071805 potassium ion transmembrane transport(GO:0071805)
0.0 2.5 GO:0051291 protein heterooligomerization(GO:0051291)
0.5 2.3 GO:0001661 conditioned taste aversion(GO:0001661)
0.2 2.3 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 2.3 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 2.2 GO:0048167 regulation of synaptic plasticity(GO:0048167)
0.0 2.0 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.5 1.5 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.1 1.4 GO:1900273 positive regulation of long-term synaptic potentiation(GO:1900273)
0.4 1.3 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.4 1.2 GO:2000501 natural killer cell chemotaxis(GO:0035747) negative regulation of lymphocyte migration(GO:2000402) regulation of natural killer cell chemotaxis(GO:2000501)
0.0 0.9 GO:0000731 DNA synthesis involved in DNA repair(GO:0000731)
0.0 0.9 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.2 0.8 GO:0097343 ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.2 0.7 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.1 0.7 GO:0035405 histone-threonine phosphorylation(GO:0035405)

Gene overrepresentation in cellular_component category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.6 6.4 GO:0032280 symmetric synapse(GO:0032280)
0.0 4.1 GO:0043204 perikaryon(GO:0043204)
0.1 3.9 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 3.0 GO:0071565 nBAF complex(GO:0071565)
0.1 2.7 GO:0031901 early endosome membrane(GO:0031901)
0.1 2.6 GO:0043194 axon initial segment(GO:0043194)
0.0 2.6 GO:0043209 myelin sheath(GO:0043209)
0.0 2.5 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 2.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.4 2.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 1.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 1.4 GO:0044327 dendritic spine head(GO:0044327)
0.1 1.3 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.3 0.9 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.2 0.7 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.7 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.1 GO:0000125 PCAF complex(GO:0000125)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 32 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 6.4 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.1 4.1 GO:0034930 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131)
0.7 4.0 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 3.9 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.1 2.7 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 2.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.5 2.5 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.2 2.5 GO:0042809 vitamin D receptor binding(GO:0042809)
0.8 2.3 GO:0070905 serine binding(GO:0070905)
0.1 2.2 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 2.0 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.4 1.5 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 1.4 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 1.4 GO:0003743 translation initiation factor activity(GO:0003743)
0.3 1.3 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.3 1.2 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 1.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.9 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.9 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.8 GO:0004708 MAP kinase kinase activity(GO:0004708)