Motif ID: Zfp691

Z-value: 0.411


Transcription factors associated with Zfp691:

Gene SymbolEntrez IDGene Name
Zfp691 ENSMUSG00000045268.7 Zfp691

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp691mm10_v2_chr4_-_119174178_119174221-0.595.6e-08Click!


Activity profile for motif Zfp691.

activity profile for motif Zfp691


Sorted Z-values histogram for motif Zfp691

Sorted Z-values for motif Zfp691



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp691

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_37050854 3.053 ENSMUST00000043794.4
 Jakmip1
janus kinase and microtubule interacting protein 1
chr10_-_86732409 3.026 ENSMUST00000070435.4
 Fabp3-ps1
fatty acid binding protein 3, muscle and heart, pseudogene 1
chr14_+_119138415 2.336 ENSMUST00000065904.3
 Hs6st3
heparan sulfate 6-O-sulfotransferase 3
chr8_+_69808672 2.316 ENSMUST00000036074.8
ENSMUST00000123453.1
 Gmip

Gem-interacting protein

chr9_-_103761820 2.246 ENSMUST00000049452.8
 Tmem108
transmembrane protein 108
chr10_+_81183263 1.897 ENSMUST00000047665.6
 Dapk3
death-associated protein kinase 3
chr9_-_58202281 1.872 ENSMUST00000163897.1
 Islr2
immunoglobulin superfamily containing leucine-rich repeat 2
chr2_-_65529275 1.709 ENSMUST00000126837.1
 Scn3a
sodium channel, voltage-gated, type III, alpha
chr2_+_181715005 1.375 ENSMUST00000071585.3
ENSMUST00000148334.1
ENSMUST00000108763.1
 Oprl1


opioid receptor-like 1


chr3_-_82074639 1.261 ENSMUST00000029635.8
 Gucy1b3
guanylate cyclase 1, soluble, beta 3
chr15_-_12592556 1.158 ENSMUST00000075317.5
 Pdzd2
PDZ domain containing 2
chr15_+_82252397 1.116 ENSMUST00000136948.1
 1500009C09Rik
RIKEN cDNA 1500009C09 gene
chr13_-_34130345 1.115 ENSMUST00000075774.3
 Tubb2b
tubulin, beta 2B class IIB
chr6_+_134640940 1.099 ENSMUST00000062755.8
 Loh12cr1
loss of heterozygosity, 12, chromosomal region 1 homolog (human)
chr10_+_81183000 1.099 ENSMUST00000178422.1
 Dapk3
death-associated protein kinase 3
chr5_-_32827109 1.085 ENSMUST00000144673.2
 Gm20671
predicted gene 20671
chr1_-_176807124 1.085 ENSMUST00000057037.7
 Cep170
centrosomal protein 170
chr4_-_129623870 1.000 ENSMUST00000106035.1
ENSMUST00000150357.1
ENSMUST00000030586.8
 Ccdc28b


coiled coil domain containing 28B


chr1_+_134193432 0.981 ENSMUST00000038445.6
 Mybph
myosin binding protein H
chr7_+_28863831 0.935 ENSMUST00000138272.1
 Lgals7
lectin, galactose binding, soluble 7
chr2_-_10130638 0.916 ENSMUST00000042290.7
 Itih2
inter-alpha trypsin inhibitor, heavy chain 2
chr2_+_29802626 0.905 ENSMUST00000080065.2
 Slc27a4
solute carrier family 27 (fatty acid transporter), member 4
chr8_+_72319033 0.896 ENSMUST00000067912.7
 Klf2
Kruppel-like factor 2 (lung)
chr10_-_112928974 0.878 ENSMUST00000099276.2
 Atxn7l3b
ataxin 7-like 3B
chr8_-_22805596 0.827 ENSMUST00000163739.1
 Ap3m2
adaptor-related protein complex 3, mu 2 subunit
chr11_+_58963790 0.822 ENSMUST00000075141.6
 Trim17
tripartite motif-containing 17
chr13_+_55622999 0.807 ENSMUST00000021963.4
 Caml
calcium modulating ligand
chr19_+_11516473 0.733 ENSMUST00000163078.1
 Ms4a6b
membrane-spanning 4-domains, subfamily A, member 6B
chr10_-_81183849 0.705 ENSMUST00000056086.4
 4930442H23Rik
RIKEN cDNA 4930442H23 gene
chr9_+_62858085 0.670 ENSMUST00000034777.6
ENSMUST00000163820.1
 Calml4

calmodulin-like 4

chr5_+_35893319 0.653 ENSMUST00000064571.4
 Afap1
actin filament associated protein 1
chr9_-_21067093 0.650 ENSMUST00000115494.2
 Zglp1
zinc finger, GATA-like protein 1
chr16_-_32165454 0.645 ENSMUST00000115163.3
ENSMUST00000144345.1
ENSMUST00000143682.1
ENSMUST00000115165.3
ENSMUST00000099991.4
ENSMUST00000130410.1
 Nrros





negative regulator of reactive oxygen species





chr12_+_86678685 0.614 ENSMUST00000021681.3
 Vash1
vasohibin 1
chr15_-_76351008 0.599 ENSMUST00000023211.9
 Sharpin
SHANK-associated RH domain interacting protein
chr7_-_12422751 0.598 ENSMUST00000080348.5
 Zfp551
zinc fingr protein 551
chr8_+_91313529 0.575 ENSMUST00000069718.7
 Fto
fat mass and obesity associated
chr6_+_70844499 0.551 ENSMUST00000034093.8
ENSMUST00000162950.1
 Eif2ak3

eukaryotic translation initiation factor 2 alpha kinase 3

chr8_+_3621529 0.545 ENSMUST00000156380.2
 Pet100
PET100 homolog (S. cerevisiae)
chr9_+_27299205 0.540 ENSMUST00000115247.1
ENSMUST00000133213.1
 Igsf9b

immunoglobulin superfamily, member 9B

chr6_+_115544664 0.534 ENSMUST00000040234.7
 Tsen2
tRNA splicing endonuclease 2 homolog (S. cerevisiae)
chr4_+_129189760 0.531 ENSMUST00000106054.2
ENSMUST00000001365.2
 Yars

tyrosyl-tRNA synthetase

chrX_-_101268218 0.486 ENSMUST00000033664.7
 Il2rg
interleukin 2 receptor, gamma chain
chr2_-_131352857 0.466 ENSMUST00000059372.4
 Rnf24
ring finger protein 24
chr2_-_155729359 0.435 ENSMUST00000040833.4
 Edem2
ER degradation enhancer, mannosidase alpha-like 2
chr3_-_33143227 0.427 ENSMUST00000108219.1
 Pex5l
peroxisomal biogenesis factor 5-like
chr15_-_76723814 0.420 ENSMUST00000036247.8
 C030006K11Rik
RIKEN cDNA C030006K11 gene
chr2_+_26591423 0.418 ENSMUST00000152988.2
ENSMUST00000149789.1
 Egfl7

EGF-like domain 7

chr11_+_120467635 0.415 ENSMUST00000140862.1
ENSMUST00000106205.1
ENSMUST00000106203.1
ENSMUST00000026900.7
 Hgs



HGF-regulated tyrosine kinase substrate



chr3_-_33143025 0.409 ENSMUST00000108226.1
 Pex5l
peroxisomal biogenesis factor 5-like
chr13_-_55528511 0.390 ENSMUST00000047877.4
 Dok3
docking protein 3
chr13_-_60897439 0.381 ENSMUST00000171347.1
ENSMUST00000021884.8
 Ctla2b

cytotoxic T lymphocyte-associated protein 2 beta

chr11_-_120467414 0.377 ENSMUST00000076921.6
 Arl16
ADP-ribosylation factor-like 16
chr2_+_24962400 0.376 ENSMUST00000028351.3
 Dph7
diphthamine biosynethesis 7
chr3_-_62605140 0.364 ENSMUST00000058535.5
 Gpr149
G protein-coupled receptor 149
chr16_+_90386382 0.340 ENSMUST00000065856.6
 Hunk
hormonally upregulated Neu-associated kinase
chr8_+_123235086 0.339 ENSMUST00000181432.1
 4933417D19Rik
RIKEN cDNA 4933417D19 gene
chr7_+_41633531 0.314 ENSMUST00000100275.3
ENSMUST00000131180.1
ENSMUST00000140964.1
ENSMUST00000045720.7
ENSMUST00000098508.2
 Zfp788




zinc finger protein 788




chr10_+_60003321 0.297 ENSMUST00000164083.2
 Ascc1
activating signal cointegrator 1 complex subunit 1
chr15_+_44196135 0.295 ENSMUST00000038856.6
ENSMUST00000110289.3
 Trhr

thyrotropin releasing hormone receptor

chr15_-_82912134 0.292 ENSMUST00000048966.5
ENSMUST00000109510.2
 Tcf20

transcription factor 20

chr12_-_71136611 0.280 ENSMUST00000021486.8
ENSMUST00000166120.1
 Timm9

translocase of inner mitochondrial membrane 9

chr9_-_108452377 0.274 ENSMUST00000035232.7
 Klhdc8b
kelch domain containing 8B
chr1_+_51289106 0.266 ENSMUST00000051572.6
 Sdpr
serum deprivation response
chr10_+_118860826 0.246 ENSMUST00000059966.4
 4932442E05Rik
RIKEN cDNA 4932442E05 gene
chr11_-_116694802 0.242 ENSMUST00000079545.5
 St6galnac2
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
chr15_-_83555681 0.237 ENSMUST00000061882.8
 Mcat
malonyl CoA:ACP acyltransferase (mitochondrial)
chr6_+_145934113 0.224 ENSMUST00000032383.7
 Sspn
sarcospan
chr2_+_91265252 0.221 ENSMUST00000028691.6
 Arfgap2
ADP-ribosylation factor GTPase activating protein 2
chr9_+_50603892 0.219 ENSMUST00000044051.4
 Timm8b
translocase of inner mitochondrial membrane 8B
chr9_-_106887000 0.211 ENSMUST00000055843.7
 Rbm15b
RNA binding motif protein 15B
chr1_-_180996145 0.208 ENSMUST00000154133.1
 Ephx1
epoxide hydrolase 1, microsomal
chr5_+_129908538 0.200 ENSMUST00000178355.1
 Nupr1l
nuclear protein transcriptional regulator 1 like
chr1_-_138856819 0.183 ENSMUST00000112025.1
 2310009B15Rik
RIKEN cDNA 2310009B15 gene
chr4_+_32657107 0.174 ENSMUST00000071642.4
ENSMUST00000178134.1
 Mdn1

midasin homolog (yeast)

chr11_-_6626030 0.162 ENSMUST00000000394.7
ENSMUST00000136682.1
 Tbrg4

transforming growth factor beta regulated gene 4

chr4_+_126046903 0.159 ENSMUST00000030675.7
 Mrps15
mitochondrial ribosomal protein S15
chr12_+_102129019 0.156 ENSMUST00000079020.4
 Slc24a4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr3_+_96635840 0.146 ENSMUST00000165842.1
 Pex11b
peroxisomal biogenesis factor 11 beta
chr7_-_45061706 0.143 ENSMUST00000107832.1
 Prrg2
proline-rich Gla (G-carboxyglutamic acid) polypeptide 2
chr7_-_38019505 0.090 ENSMUST00000085513.4
 Uri1
URI1, prefoldin-like chaperone
chr6_+_28475101 0.083 ENSMUST00000168362.1
 Snd1
staphylococcal nuclease and tudor domain containing 1
chr2_-_170194033 0.044 ENSMUST00000180625.1
 Gm17619
predicted gene, 17619
chr2_-_130664565 0.044 ENSMUST00000089559.4
 Ddrgk1
DDRGK domain containing 1
chr5_+_95956916 0.032 ENSMUST00000023840.5
 Cxcl13
chemokine (C-X-C motif) ligand 13
chr10_-_93891141 0.029 ENSMUST00000180840.1
 Metap2
methionine aminopeptidase 2
chr2_-_130284422 0.007 ENSMUST00000028892.4
 Idh3b
isocitrate dehydrogenase 3 (NAD+) beta
chr3_-_92429403 0.007 ENSMUST00000047300.7
 Gm9774
predicted pseudogene 9774
chr10_-_60002993 0.005 ENSMUST00000182116.1
 Anapc16
anaphase promoting complex subunit 16
chr14_-_20348040 0.002 ENSMUST00000022344.2
 Ecd
ecdysoneless homolog (Drosophila)
chr14_-_70323783 0.001 ENSMUST00000151011.1
 Slc39a14
solute carrier family 39 (zinc transporter), member 14

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0031038 myosin II filament organization(GO:0031038) regulation of myosin II filament organization(GO:0043519)
0.5 1.4 GO:1904059 positive regulation of sensory perception of pain(GO:1904058) regulation of locomotor rhythm(GO:1904059)
0.4 2.3 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.3 1.7 GO:0046684 response to pyrethroid(GO:0046684)
0.2 0.6 GO:0035552 oxidative single-stranded DNA demethylation(GO:0035552)
0.2 0.5 GO:0032829 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829)
0.2 0.6 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.1 0.9 GO:0071499 response to laminar fluid shear stress(GO:0034616) cellular response to laminar fluid shear stress(GO:0071499)
0.1 0.4 GO:1904154 trimming of terminal mannose on B branch(GO:0036509) positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.1 0.5 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.1 0.5 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.1 0.4 GO:0048162 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.1 0.8 GO:0051461 protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.1 0.9 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.1 0.4 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 0.6 GO:0032055 negative regulation of translation in response to stress(GO:0032055) cellular response to cold(GO:0070417)
0.1 0.6 GO:2000348 protein linear polyubiquitination(GO:0097039) regulation of CD40 signaling pathway(GO:2000348)
0.1 0.3 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 1.3 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.0 0.5 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.5 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151)
0.0 0.2 GO:0097503 sialylation(GO:0097503)
0.0 0.8 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.9 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.4 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 1.9 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.3 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.1 GO:0044375 regulation of peroxisome size(GO:0044375)
0.0 0.9 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.0 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0 0.8 GO:0001881 receptor recycling(GO:0001881)
0.0 0.6 GO:0006801 superoxide metabolic process(GO:0006801)
0.0 0.2 GO:0097186 amelogenesis(GO:0097186)
0.0 0.8 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.2 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.4 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.1 0.6 GO:0071797 LUBAC complex(GO:0071797)
0.1 1.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 1.7 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.1 1.0 GO:0032982 myosin filament(GO:0032982)
0.1 0.5 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 0.6 GO:0045177 apical part of cell(GO:0045177)
0.1 0.8 GO:1904115 axon cytoplasm(GO:1904115)
0.1 0.3 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.5 GO:0060077 inhibitory synapse(GO:0060077)
0.0 2.5 GO:0005884 actin filament(GO:0005884)
0.0 0.2 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.9 GO:0031526 brush border membrane(GO:0031526)
0.0 1.1 GO:0005814 centriole(GO:0005814)
0.0 0.1 GO:0097433 dense body(GO:0097433)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.7 GO:0043522 leucine zipper domain binding(GO:0043522)
0.2 3.1 GO:0050811 GABA receptor binding(GO:0050811)
0.2 0.8 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 1.7 GO:0042923 neuropeptide binding(GO:0042923)
0.1 0.6 GO:0035514 DNA demethylase activity(GO:0035514) oxidative RNA demethylase activity(GO:0035515)
0.1 1.3 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 0.5 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.1 1.9 GO:0031402 sodium ion binding(GO:0031402)
0.1 0.6 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 0.5 GO:0000213 tRNA-intron endonuclease activity(GO:0000213) endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.1 0.9 GO:0034943 acyl-CoA ligase activity(GO:0003996) 3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity(GO:0010435) 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity(GO:0018854) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity(GO:0018855) benzoyl acetate-CoA ligase activity(GO:0018856) 2,4-dichlorobenzoate-CoA ligase activity(GO:0018857) very long-chain fatty acid-CoA ligase activity(GO:0031957) pivalate-CoA ligase activity(GO:0034783) cyclopropanecarboxylate-CoA ligase activity(GO:0034793) adipate-CoA ligase activity(GO:0034796) citronellyl-CoA ligase activity(GO:0034823) mentha-1,3-dione-CoA ligase activity(GO:0034841) thiophene-2-carboxylate-CoA ligase activity(GO:0034842) 2,4,4-trimethylpentanoate-CoA ligase activity(GO:0034865) cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034942) trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034943) branched-chain acyl-CoA synthetase (ADP-forming) activity(GO:0043759) aryl-CoA synthetase (ADP-forming) activity(GO:0043762) 3-hydroxypropionyl-CoA synthetase activity(GO:0043955) perillic acid:CoA ligase (ADP-forming) activity(GO:0052685) perillic acid:CoA ligase (AMP-forming) activity(GO:0052686) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity(GO:0052687) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity(GO:0052688) pristanate-CoA ligase activity(GO:0070251) malonyl-CoA synthetase activity(GO:0090409)
0.1 2.3 GO:0034930 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131)
0.0 0.4 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.2 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.2 GO:0008932 lytic endotransglycosylase activity(GO:0008932)
0.0 0.7 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.2 GO:0004312 fatty acid synthase activity(GO:0004312)
0.0 0.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)
0.0 0.0 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)