Motif ID: Zic3
Z-value: 0.761
Transcription factors associated with Zic3:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Zic3 | ENSMUSG00000067860.5 | Zic3 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Zic3 | mm10_v2_chrX_+_58030999_58031018 | 0.65 | 1.5e-09 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 157 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.4 | 5.7 | GO:0055099 | response to high density lipoprotein particle(GO:0055099) |
| 0.7 | 4.5 | GO:0003383 | apical constriction(GO:0003383) |
| 0.2 | 4.5 | GO:0090005 | negative regulation of establishment of protein localization to plasma membrane(GO:0090005) |
| 0.4 | 4.1 | GO:0016127 | cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127) |
| 0.1 | 3.4 | GO:0045669 | positive regulation of osteoblast differentiation(GO:0045669) |
| 0.6 | 3.0 | GO:0070345 | negative regulation of fat cell proliferation(GO:0070345) |
| 0.0 | 3.0 | GO:0006631 | fatty acid metabolic process(GO:0006631) |
| 0.3 | 2.8 | GO:0051574 | positive regulation of histone H3-K9 methylation(GO:0051574) |
| 0.2 | 2.4 | GO:1903608 | protein localization to cytoplasmic stress granule(GO:1903608) |
| 0.6 | 2.3 | GO:0060032 | notochord regression(GO:0060032) |
| 0.3 | 2.2 | GO:0071557 | histone H3-K27 demethylation(GO:0071557) |
| 0.1 | 2.2 | GO:0038092 | nodal signaling pathway(GO:0038092) |
| 0.3 | 2.1 | GO:0070493 | thrombin receptor signaling pathway(GO:0070493) |
| 0.0 | 2.1 | GO:1901998 | toxin transport(GO:1901998) |
| 0.0 | 2.1 | GO:0070527 | platelet aggregation(GO:0070527) |
| 0.7 | 2.0 | GO:0060598 | dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598) |
| 0.0 | 2.0 | GO:0048843 | negative regulation of axon extension involved in axon guidance(GO:0048843) |
| 0.1 | 1.9 | GO:0034501 | protein localization to kinetochore(GO:0034501) |
| 0.1 | 1.9 | GO:0046069 | cGMP catabolic process(GO:0046069) |
| 0.0 | 1.8 | GO:0006970 | response to osmotic stress(GO:0006970) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 56 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 4.5 | GO:0033269 | internode region of axon(GO:0033269) |
| 0.2 | 4.1 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
| 0.1 | 2.9 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.6 | 2.4 | GO:0097165 | nuclear stress granule(GO:0097165) |
| 0.2 | 2.3 | GO:0097542 | ciliary tip(GO:0097542) |
| 0.0 | 2.1 | GO:0031941 | filamentous actin(GO:0031941) |
| 0.0 | 2.0 | GO:0005814 | centriole(GO:0005814) |
| 0.1 | 1.9 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
| 0.0 | 1.9 | GO:0005777 | peroxisome(GO:0005777) microbody(GO:0042579) |
| 0.2 | 1.5 | GO:0000796 | condensin complex(GO:0000796) |
| 0.0 | 1.5 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.2 | 1.3 | GO:0001940 | male pronucleus(GO:0001940) |
| 0.0 | 1.3 | GO:0005903 | brush border(GO:0005903) |
| 0.1 | 1.2 | GO:0001527 | microfibril(GO:0001527) |
| 0.2 | 1.1 | GO:0035189 | Rb-E2F complex(GO:0035189) |
| 0.2 | 1.0 | GO:0002111 | BRCA2-BRAF35 complex(GO:0002111) |
| 0.0 | 1.0 | GO:0032587 | ruffle membrane(GO:0032587) |
| 0.2 | 0.9 | GO:0016035 | zeta DNA polymerase complex(GO:0016035) |
| 0.2 | 0.9 | GO:0032983 | kainate selective glutamate receptor complex(GO:0032983) |
| 0.1 | 0.9 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 105 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 6.8 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.0 | 5.0 | GO:0001047 | core promoter binding(GO:0001047) |
| 0.3 | 4.5 | GO:0005522 | profilin binding(GO:0005522) |
| 0.1 | 4.5 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
| 1.4 | 4.1 | GO:0030226 | apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) |
| 0.7 | 4.1 | GO:0003854 | 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854) |
| 0.0 | 3.2 | GO:0016829 | lyase activity(GO:0016829) |
| 0.0 | 2.9 | GO:0003714 | transcription corepressor activity(GO:0003714) |
| 0.1 | 2.8 | GO:0032452 | histone demethylase activity(GO:0032452) |
| 0.1 | 2.5 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.0 | 2.3 | GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) |
| 0.3 | 2.2 | GO:0071558 | histone demethylase activity (H3-K27 specific)(GO:0071558) |
| 0.2 | 2.1 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 0.2 | 2.0 | GO:0038191 | neuropilin binding(GO:0038191) |
| 0.5 | 1.9 | GO:0043515 | kinetochore binding(GO:0043515) |
| 0.3 | 1.9 | GO:0048101 | calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
| 0.4 | 1.7 | GO:0016708 | nitric oxide dioxygenase activity(GO:0008941) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor(GO:0016708) iron-cytochrome-c reductase activity(GO:0047726) |
| 0.0 | 1.7 | GO:0001158 | enhancer sequence-specific DNA binding(GO:0001158) |
| 0.5 | 1.6 | GO:0017153 | sodium:dicarboxylate symporter activity(GO:0017153) |
| 0.2 | 1.6 | GO:0005138 | interleukin-6 receptor binding(GO:0005138) |
