Motif ID: Zic4

Z-value: 0.897


Transcription factors associated with Zic4:

Gene SymbolEntrez IDGene Name
Zic4 ENSMUSG00000036972.8 Zic4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zic4mm10_v2_chr9_+_91368811_91368828-0.263.0e-02Click!


Activity profile for motif Zic4.

activity profile for motif Zic4


Sorted Z-values histogram for motif Zic4

Sorted Z-values for motif Zic4



Network of associatons between targets according to the STRING database.



First level regulatory network of Zic4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_180499893 5.747 ENSMUST00000029084.2
Ntsr1
neurotensin receptor 1
chr4_+_141368116 4.649 ENSMUST00000006380.4
Fam131c
family with sequence similarity 131, member C
chr9_-_29412204 4.445 ENSMUST00000115237.1
Ntm
neurotrimin
chr4_+_152338619 4.323 ENSMUST00000030775.5
ENSMUST00000164662.1
Chd5

chromodomain helicase DNA binding protein 5

chr4_+_152338887 4.283 ENSMUST00000005175.4
Chd5
chromodomain helicase DNA binding protein 5
chr19_+_47178820 3.549 ENSMUST00000111808.3
Neurl1a
neuralized homolog 1A (Drosophila)
chr19_+_4099998 3.462 ENSMUST00000049658.7
Pitpnm1
phosphatidylinositol transfer protein, membrane-associated 1
chr5_-_139325616 3.427 ENSMUST00000110865.1
Adap1
ArfGAP with dual PH domains 1
chr2_-_152951456 3.317 ENSMUST00000123121.2
Dusp15
dual specificity phosphatase-like 15
chr7_-_47133684 3.181 ENSMUST00000102626.1
Ptpn5
protein tyrosine phosphatase, non-receptor type 5
chr17_-_29237759 3.144 ENSMUST00000137727.1
ENSMUST00000024805.7
Cpne5

copine V

chr7_-_47133395 3.132 ENSMUST00000107617.1
Ptpn5
protein tyrosine phosphatase, non-receptor type 5
chr19_+_4855129 3.055 ENSMUST00000119694.1
Ctsf
cathepsin F
chr17_+_46297917 2.898 ENSMUST00000166617.1
ENSMUST00000170271.1
Dlk2

delta-like 2 homolog (Drosophila)

chr6_-_35308110 2.894 ENSMUST00000031868.4
Slc13a4
solute carrier family 13 (sodium/sulfate symporters), member 4
chr2_-_152951547 2.822 ENSMUST00000037715.6
Dusp15
dual specificity phosphatase-like 15
chr2_-_152951688 2.724 ENSMUST00000109811.3
Dusp15
dual specificity phosphatase-like 15
chr4_+_104367549 2.664 ENSMUST00000106830.2
Dab1
disabled 1
chr11_+_98741805 2.661 ENSMUST00000064187.5
Thra
thyroid hormone receptor alpha
chr1_+_91179822 2.617 ENSMUST00000097648.4
ENSMUST00000165855.1
Ramp1

receptor (calcitonin) activity modifying protein 1

chrX_+_73503074 2.593 ENSMUST00000114479.1
ENSMUST00000088429.1
ENSMUST00000033744.5
Atp2b3


ATPase, Ca++ transporting, plasma membrane 3


chr11_+_98741871 2.529 ENSMUST00000103139.4
Thra
thyroid hormone receptor alpha
chr1_-_43163891 2.456 ENSMUST00000008280.7
Fhl2
four and a half LIM domains 2
chr11_+_5861886 2.347 ENSMUST00000102923.3
Aebp1
AE binding protein 1
chr6_+_99692679 2.290 ENSMUST00000101122.1
Gpr27
G protein-coupled receptor 27
chr2_+_85136355 2.254 ENSMUST00000057019.7
Aplnr
apelin receptor
chr15_-_33687840 2.218 ENSMUST00000042021.3
Tspyl5
testis-specific protein, Y-encoded-like 5
chr1_-_12991109 2.119 ENSMUST00000115403.2
ENSMUST00000115402.1
Slco5a1

solute carrier organic anion transporter family, member 5A1

chr6_-_59426279 2.060 ENSMUST00000051065.4
Gprin3
GPRIN family member 3
chr19_-_12501996 1.977 ENSMUST00000045521.7
Dtx4
deltex 4 homolog (Drosophila)
chr19_+_48206025 1.948 ENSMUST00000078880.5
Sorcs3
sortilin-related VPS10 domain containing receptor 3
chr4_-_72200833 1.939 ENSMUST00000102848.2
ENSMUST00000072695.6
ENSMUST00000107337.1
ENSMUST00000074216.7
Tle1



transducin-like enhancer of split 1, homolog of Drosophila E(spl)



chr5_-_113310729 1.878 ENSMUST00000112325.1
ENSMUST00000048112.6
Sgsm1

small G protein signaling modulator 1

chr6_+_65671590 1.877 ENSMUST00000054351.4
Ndnf
neuron-derived neurotrophic factor
chr17_+_37045963 1.764 ENSMUST00000025338.9
Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr19_-_6235804 1.686 ENSMUST00000025695.9
Ppp2r5b
protein phosphatase 2, regulatory subunit B (B56), beta isoform
chr5_-_113310697 1.685 ENSMUST00000154248.1
Sgsm1
small G protein signaling modulator 1
chr2_+_180598219 1.670 ENSMUST00000103059.1
Col9a3
collagen, type IX, alpha 3
chr1_-_21961581 1.652 ENSMUST00000029667.6
ENSMUST00000173058.1
ENSMUST00000173404.1
Kcnq5


potassium voltage-gated channel, subfamily Q, member 5


chr11_+_46055973 1.583 ENSMUST00000011400.7
Adam19
a disintegrin and metallopeptidase domain 19 (meltrin beta)
chr11_+_24076529 1.495 ENSMUST00000148087.1
Gm12063
predicted gene 12063
chrX_+_85574018 1.490 ENSMUST00000048250.3
ENSMUST00000137438.1
ENSMUST00000146063.1
Tab3


TGF-beta activated kinase 1/MAP3K7 binding protein 3


chr12_+_24651346 1.477 ENSMUST00000020982.5
Klf11
Kruppel-like factor 11
chr2_+_120977017 1.457 ENSMUST00000067582.7
Tmem62
transmembrane protein 62
chr4_-_133602168 1.456 ENSMUST00000057311.3
Sfn
stratifin
chr9_-_107710475 1.454 ENSMUST00000080560.3
Sema3f
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr10_+_106470281 1.440 ENSMUST00000029404.9
ENSMUST00000169303.1
Ppfia2

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

chr9_-_35558522 1.439 ENSMUST00000034612.5
Ddx25
DEAD (Asp-Glu-Ala-Asp) box polypeptide 25
chr17_+_79051906 1.406 ENSMUST00000040789.4
Qpct
glutaminyl-peptide cyclotransferase (glutaminyl cyclase)
chr2_+_131909928 1.398 ENSMUST00000091288.6
Prnp
prion protein
chr11_-_85139939 1.377 ENSMUST00000108075.2
Usp32
ubiquitin specific peptidase 32
chr14_-_64455903 1.374 ENSMUST00000067927.7
Msra
methionine sulfoxide reductase A
chr14_-_29721835 1.364 ENSMUST00000022567.7
Cacna2d3
calcium channel, voltage-dependent, alpha2/delta subunit 3
chr7_+_28766747 1.334 ENSMUST00000170068.1
ENSMUST00000072965.4
Sirt2

sirtuin 2

chr4_+_117096049 1.326 ENSMUST00000030443.5
Ptch2
patched homolog 2
chr7_+_28458658 1.229 ENSMUST00000108288.3
ENSMUST00000055110.9
Lrfn1

leucine rich repeat and fibronectin type III domain containing 1

chr19_+_5447692 1.228 ENSMUST00000025850.5
Fosl1
fos-like antigen 1
chr12_-_67222549 1.217 ENSMUST00000037181.8
Mdga2
MAM domain containing glycosylphosphatidylinositol anchor 2
chr8_-_64849818 1.201 ENSMUST00000034017.7
Klhl2
kelch-like 2, Mayven
chr8_-_83166170 1.178 ENSMUST00000098605.2
Gm10645
predicted gene 10645
chr11_+_93099284 1.142 ENSMUST00000092780.3
ENSMUST00000107863.2
Car10

carbonic anhydrase 10

chr5_-_142509653 1.071 ENSMUST00000110784.1
Radil
Ras association and DIL domains
chrX_-_107403295 1.068 ENSMUST00000033591.5
Itm2a
integral membrane protein 2A
chr16_+_20733104 1.045 ENSMUST00000115423.1
ENSMUST00000007171.6
Chrd

chordin

chr7_-_57387172 1.011 ENSMUST00000068911.6
Gabrg3
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3
chr4_+_130792513 0.969 ENSMUST00000070478.3
Sdc3
syndecan 3
chr3_-_8964037 0.955 ENSMUST00000091354.5
ENSMUST00000094381.4
Tpd52

tumor protein D52

chr5_+_139543889 0.947 ENSMUST00000174792.1
ENSMUST00000031523.8
Uncx

UNC homeobox

chr17_-_71310952 0.942 ENSMUST00000024849.9
Emilin2
elastin microfibril interfacer 2
chr2_+_131909951 0.939 ENSMUST00000124100.1
ENSMUST00000136783.1
PRND

prion protein gene complex (Prn), transcript variant 1, mRNA

chr16_+_35983424 0.918 ENSMUST00000173555.1
Kpna1
karyopherin (importin) alpha 1
chr12_+_112146187 0.913 ENSMUST00000128402.2
Kif26a
kinesin family member 26A
chr2_+_147187424 0.912 ENSMUST00000144411.1
6430503K07Rik
RIKEN cDNA 6430503K07 gene
chr3_-_20035285 0.909 ENSMUST00000108321.1
ENSMUST00000012580.6
Hps3

Hermansky-Pudlak syndrome 3 homolog (human)

chr4_+_42158092 0.891 ENSMUST00000098122.2
Gm13306
predicted gene 13306
chr17_+_37045980 0.882 ENSMUST00000174456.1
Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr3_-_110142996 0.865 ENSMUST00000156177.2
Ntng1
netrin G1
chr12_-_12941827 0.823 ENSMUST00000043396.7
Mycn
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr17_-_57059795 0.822 ENSMUST00000040280.7
Slc25a23
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
chr16_+_35983307 0.774 ENSMUST00000004054.6
Kpna1
karyopherin (importin) alpha 1
chr2_+_164960809 0.771 ENSMUST00000124372.1
Slc12a5
solute carrier family 12, member 5
chr11_+_57801575 0.752 ENSMUST00000020826.5
Sap30l
SAP30-like
chr4_-_24851079 0.747 ENSMUST00000084781.5
ENSMUST00000108218.3
Klhl32

kelch-like 32

chr17_-_26508463 0.736 ENSMUST00000025025.6
Dusp1
dual specificity phosphatase 1
chr1_+_75546449 0.735 ENSMUST00000150142.1
Slc4a3
solute carrier family 4 (anion exchanger), member 3
chr4_+_128883549 0.710 ENSMUST00000035667.8
Trim62
tripartite motif-containing 62
chr3_-_107986408 0.708 ENSMUST00000012348.2
Gstm2
glutathione S-transferase, mu 2
chr2_-_29253001 0.692 ENSMUST00000071201.4
Ntng2
netrin G2
chr5_+_43233463 0.685 ENSMUST00000169035.1
ENSMUST00000166713.1
Cpeb2

cytoplasmic polyadenylation element binding protein 2

chr2_+_164879358 0.681 ENSMUST00000041643.3
Pcif1
PDX1 C-terminal inhibiting factor 1
chr11_-_78497458 0.657 ENSMUST00000108287.3
Sarm1
sterile alpha and HEAT/Armadillo motif containing 1
chr9_+_58554799 0.654 ENSMUST00000098676.2
Gm10657
predicted gene 10657
chr13_-_48625571 0.652 ENSMUST00000035824.9
Ptpdc1
protein tyrosine phosphatase domain containing 1
chr6_+_47877204 0.625 ENSMUST00000061890.7
Zfp282
zinc finger protein 282
chr8_+_107031218 0.622 ENSMUST00000034388.9
Vps4a
vacuolar protein sorting 4a (yeast)
chr9_-_63146980 0.593 ENSMUST00000055281.7
ENSMUST00000119146.1
Skor1

SKI family transcriptional corepressor 1

chr17_-_34031544 0.592 ENSMUST00000025186.8
Slc39a7
solute carrier family 39 (zinc transporter), member 7
chr9_+_108460518 0.586 ENSMUST00000061209.5
Ccdc71
coiled-coil domain containing 71
chr13_-_95223045 0.575 ENSMUST00000162292.1
Pde8b
phosphodiesterase 8B
chr7_+_27653906 0.569 ENSMUST00000008088.7
Ttc9b
tetratricopeptide repeat domain 9B
chr11_+_75732869 0.561 ENSMUST00000067664.3
Ywhae
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
chr17_-_83631892 0.558 ENSMUST00000051482.1
Kcng3
potassium voltage-gated channel, subfamily G, member 3
chr17_-_34031644 0.556 ENSMUST00000171872.1
Slc39a7
solute carrier family 39 (zinc transporter), member 7
chrX_-_7740206 0.555 ENSMUST00000128289.1
Ccdc120
coiled-coil domain containing 120
chr19_-_4477447 0.551 ENSMUST00000059295.3
Syt12
synaptotagmin XII
chr11_+_93996082 0.547 ENSMUST00000041956.7
Spag9
sperm associated antigen 9
chr6_+_141524379 0.544 ENSMUST00000032362.9
Slco1c1
solute carrier organic anion transporter family, member 1c1
chr17_+_83706170 0.525 ENSMUST00000067826.8
Mta3
metastasis associated 3
chr6_-_97487801 0.519 ENSMUST00000113353.1
ENSMUST00000032146.7
Frmd4b

FERM domain containing 4B

chr15_-_97831460 0.501 ENSMUST00000079838.7
ENSMUST00000118294.1
Hdac7

histone deacetylase 7

chr3_+_97658212 0.496 ENSMUST00000045743.6
Prkab2
protein kinase, AMP-activated, beta 2 non-catalytic subunit
chr11_-_102946688 0.495 ENSMUST00000057849.5
C1ql1
complement component 1, q subcomponent-like 1
chr4_-_62360436 0.490 ENSMUST00000084527.3
ENSMUST00000098033.3
Fkbp15

FK506 binding protein 15

chr11_+_121702591 0.486 ENSMUST00000125580.1
Metrnl
meteorin, glial cell differentiation regulator-like
chr4_-_129121699 0.483 ENSMUST00000135763.1
ENSMUST00000149763.1
ENSMUST00000164649.1
Hpca


hippocalcin


chr8_+_72240315 0.469 ENSMUST00000126885.1
Ap1m1
adaptor-related protein complex AP-1, mu subunit 1
chr3_+_107595031 0.467 ENSMUST00000014747.1
Alx3
aristaless-like homeobox 3
chr14_-_54913089 0.461 ENSMUST00000050772.7
Slc22a17
solute carrier family 22 (organic cation transporter), member 17
chr7_-_98119482 0.451 ENSMUST00000138627.1
ENSMUST00000107127.1
ENSMUST00000107128.1
Myo7a


myosin VIIA


chr2_-_167062607 0.448 ENSMUST00000128676.1
Znfx1
zinc finger, NFX1-type containing 1
chr6_+_97807014 0.443 ENSMUST00000043637.7
Mitf
microphthalmia-associated transcription factor
chr3_-_107986360 0.435 ENSMUST00000066530.6
Gstm2
glutathione S-transferase, mu 2
chr11_+_75733037 0.430 ENSMUST00000131398.1
Ywhae
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
chr2_-_130642770 0.423 ENSMUST00000045761.6
Lzts3
leucine zipper, putative tumor suppressor family member 3
chr17_-_34031684 0.422 ENSMUST00000169397.1
Slc39a7
solute carrier family 39 (zinc transporter), member 7
chr11_-_78497734 0.420 ENSMUST00000061174.6
Sarm1
sterile alpha and HEAT/Armadillo motif containing 1
chr4_-_57143437 0.419 ENSMUST00000095076.3
ENSMUST00000030142.3
Epb4.1l4b

erythrocyte protein band 4.1-like 4b

chr2_-_167062981 0.401 ENSMUST00000048988.7
Znfx1
zinc finger, NFX1-type containing 1
chr18_-_24603791 0.396 ENSMUST00000070726.3
Slc39a6
solute carrier family 39 (metal ion transporter), member 6
chr4_-_62360524 0.396 ENSMUST00000107461.1
ENSMUST00000084528.3
Fkbp15

FK506 binding protein 15

chr8_-_36613937 0.393 ENSMUST00000033923.7
Dlc1
deleted in liver cancer 1
chr7_-_25297967 0.388 ENSMUST00000005583.5
Pafah1b3
platelet-activating factor acetylhydrolase, isoform 1b, subunit 3
chr9_+_46012810 0.374 ENSMUST00000126865.1
Sik3
SIK family kinase 3
chr18_-_24603464 0.372 ENSMUST00000154205.1
Slc39a6
solute carrier family 39 (metal ion transporter), member 6
chr13_-_37994111 0.362 ENSMUST00000021864.6
Ssr1
signal sequence receptor, alpha
chr1_-_168431896 0.359 ENSMUST00000176540.1
Pbx1
pre B cell leukemia homeobox 1
chrX_-_49797700 0.357 ENSMUST00000033442.7
ENSMUST00000114891.1
Igsf1

immunoglobulin superfamily, member 1

chr7_-_16476765 0.350 ENSMUST00000002053.8
Npas1
neuronal PAS domain protein 1
chr7_+_45873127 0.343 ENSMUST00000107718.1
Kdelr1
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
chr2_-_181288016 0.343 ENSMUST00000049032.6
Gmeb2
glucocorticoid modulatory element binding protein 2
chr7_-_34654342 0.331 ENSMUST00000108069.1
Kctd15
potassium channel tetramerisation domain containing 15
chr9_-_58555129 0.327 ENSMUST00000165365.1
Cd276
CD276 antigen
chr17_+_26113286 0.324 ENSMUST00000025010.7
Tmem8
transmembrane protein 8 (five membrane-spanning domains)
chr8_+_87472838 0.319 ENSMUST00000180806.2
Gm2694
predicted gene 2694
chr11_-_116853083 0.319 ENSMUST00000092404.6
Srsf2
serine/arginine-rich splicing factor 2
chr15_+_99224976 0.308 ENSMUST00000041415.3
Kcnh3
potassium voltage-gated channel, subfamily H (eag-related), member 3
chr2_-_73775341 0.308 ENSMUST00000112024.3
ENSMUST00000166199.1
ENSMUST00000180045.1
Chn1


chimerin (chimaerin) 1


chr6_-_115251839 0.304 ENSMUST00000032462.6
Timp4
tissue inhibitor of metalloproteinase 4
chr8_-_64693027 0.298 ENSMUST00000048967.7
Cpe
carboxypeptidase E
chr8_+_72240018 0.296 ENSMUST00000003117.8
Ap1m1
adaptor-related protein complex AP-1, mu subunit 1
chr8_+_87473116 0.284 ENSMUST00000182650.1
ENSMUST00000182758.1
ENSMUST00000181898.1
Gm2694


predicted gene 2694


chr17_-_45593626 0.279 ENSMUST00000163905.1
ENSMUST00000167692.1
Slc29a1

solute carrier family 29 (nucleoside transporters), member 1

chr2_-_153529941 0.276 ENSMUST00000035346.7
8430427H17Rik
RIKEN cDNA 8430427H17 gene
chr9_-_43105718 0.270 ENSMUST00000165665.1
Arhgef12
Rho guanine nucleotide exchange factor (GEF) 12
chr4_-_156197479 0.267 ENSMUST00000075787.6
ENSMUST00000180572.1
Agrn

agrin

chr6_-_83054415 0.266 ENSMUST00000113962.1
ENSMUST00000089645.6
ENSMUST00000113963.1
Htra2


HtrA serine peptidase 2


chr12_-_31499541 0.260 ENSMUST00000101499.3
ENSMUST00000064240.6
ENSMUST00000085487.5
Cbll1


Casitas B-lineage lymphoma-like 1


chr10_+_127380799 0.259 ENSMUST00000111628.2
R3hdm2
R3H domain containing 2
chr7_-_143460989 0.257 ENSMUST00000167912.1
ENSMUST00000037287.6
Cdkn1c

cyclin-dependent kinase inhibitor 1C (P57)

chr12_-_57546121 0.250 ENSMUST00000044380.6
Foxa1
forkhead box A1
chr9_+_65346066 0.245 ENSMUST00000048184.2
Pdcd7
programmed cell death 7
chr5_-_20882072 0.237 ENSMUST00000118174.1
Phtf2
putative homeodomain transcription factor 2
chr6_-_39118211 0.237 ENSMUST00000038398.6
Parp12
poly (ADP-ribose) polymerase family, member 12
chr7_-_25297866 0.233 ENSMUST00000148150.1
ENSMUST00000155118.1
Pafah1b3

platelet-activating factor acetylhydrolase, isoform 1b, subunit 3

chr10_-_61979073 0.232 ENSMUST00000105453.1
ENSMUST00000105452.2
ENSMUST00000105454.2
Col13a1


collagen, type XIII, alpha 1


chr12_+_102128718 0.220 ENSMUST00000159329.1
Slc24a4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr2_-_71367749 0.210 ENSMUST00000151937.1
Slc25a12
solute carrier family 25 (mitochondrial carrier, Aralar), member 12
chr2_+_91922178 0.210 ENSMUST00000170432.1
Chrm4
cholinergic receptor, muscarinic 4
chr1_+_87853264 0.205 ENSMUST00000027517.7
Dgkd
diacylglycerol kinase, delta
chr11_-_71033462 0.195 ENSMUST00000156068.2
6330403K07Rik
RIKEN cDNA 6330403K07 gene
chr4_+_129513581 0.188 ENSMUST00000062356.6
Marcksl1
MARCKS-like 1
chr7_-_137314394 0.187 ENSMUST00000168203.1
ENSMUST00000106118.2
ENSMUST00000169486.2
ENSMUST00000033378.5
Ebf3



early B cell factor 3



chr4_-_129121234 0.183 ENSMUST00000030572.3
Hpca
hippocalcin
chr2_-_167661496 0.183 ENSMUST00000125544.2
ENSMUST00000006587.6
Gm20431
Tmem189
predicted gene 20431
transmembrane protein 189
chr10_-_81365807 0.182 ENSMUST00000020456.4
4930404N11Rik
RIKEN cDNA 4930404N11 gene
chrX_-_74085586 0.174 ENSMUST00000123362.1
ENSMUST00000140399.1
ENSMUST00000100750.3
Mecp2


methyl CpG binding protein 2


chr18_-_80713062 0.172 ENSMUST00000170905.1
ENSMUST00000078049.4
Nfatc1

nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1

chr8_+_87472805 0.164 ENSMUST00000180700.2
ENSMUST00000182174.1
ENSMUST00000181159.1
Gm2694


predicted gene 2694


chr17_-_29347902 0.155 ENSMUST00000095427.4
ENSMUST00000118366.1
Mtch1

mitochondrial carrier homolog 1 (C. elegans)

chr7_-_126503408 0.148 ENSMUST00000040202.8
Atxn2l
ataxin 2-like
chr9_+_46012822 0.144 ENSMUST00000120463.2
ENSMUST00000120247.1
Sik3

SIK family kinase 3

chrX_+_71364901 0.123 ENSMUST00000132837.1
Mtmr1
myotubularin related protein 1
chr7_+_45872772 0.117 ENSMUST00000002855.5
ENSMUST00000107719.1
Kdelr1

KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1

chr14_+_25980039 0.111 ENSMUST00000173155.1
Duxbl1
double homeobox B-like 1
chrX_-_10216918 0.096 ENSMUST00000072393.2
ENSMUST00000044598.6
ENSMUST00000073392.4
ENSMUST00000115533.1
ENSMUST00000115532.1
Rpgr




retinitis pigmentosa GTPase regulator




chr11_-_69920892 0.095 ENSMUST00000152589.1
ENSMUST00000108612.1
ENSMUST00000108611.1
Eif5a


eukaryotic translation initiation factor 5A


chr10_+_127380591 0.095 ENSMUST00000166820.1
R3hdm2
R3H domain containing 2
chr1_+_153665666 0.094 ENSMUST00000111814.1
ENSMUST00000111810.1
Rgs8

regulator of G-protein signaling 8

chr7_+_27591513 0.087 ENSMUST00000108344.2
Akt2
thymoma viral proto-oncogene 2
chr4_-_151996113 0.075 ENSMUST00000055688.9
Phf13
PHD finger protein 13
chr5_+_4192367 0.071 ENSMUST00000177258.1
Gm9897
predicted gene 9897
chr17_-_45595502 0.068 ENSMUST00000171081.1
ENSMUST00000172301.1
ENSMUST00000167332.1
ENSMUST00000170488.1
ENSMUST00000167195.1
ENSMUST00000064889.6
ENSMUST00000051574.6
ENSMUST00000164217.1
Slc29a1







solute carrier family 29 (nucleoside transporters), member 1







chrY_+_897782 0.064 ENSMUST00000055032.7
Kdm5d
lysine (K)-specific demethylase 5D
chr10_-_80577285 0.062 ENSMUST00000038558.8
Klf16
Kruppel-like factor 16
chrX_+_71364745 0.061 ENSMUST00000114601.1
ENSMUST00000146213.1
ENSMUST00000015358.1
Mtmr1


myotubularin related protein 1


chr5_-_72974702 0.058 ENSMUST00000043711.8
Gm10135
predicted gene 10135
chr3_+_103914560 0.058 ENSMUST00000106806.1
Rsbn1
rosbin, round spermatid basic protein 1
chr16_-_30388530 0.053 ENSMUST00000100013.2
ENSMUST00000061350.6
Atp13a3

ATPase type 13A3

chr8_-_45382198 0.041 ENSMUST00000093526.6
Fam149a
family with sequence similarity 149, member A
chr7_-_97579382 0.041 ENSMUST00000151840.1
ENSMUST00000135998.1
ENSMUST00000144858.1
ENSMUST00000146605.1
ENSMUST00000072725.5
ENSMUST00000138060.1
ENSMUST00000154853.1
ENSMUST00000136757.1
ENSMUST00000124552.1
Aamdc








adipogenesis associated Mth938 domain containing









Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.2 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
1.7 8.6 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
1.4 5.7 GO:1903802 positive regulation of arachidonic acid secretion(GO:0090238) L-glutamate(1-) import into cell(GO:1903802) L-glutamate import into cell(GO:1990123)
1.3 6.3 GO:2001025 positive regulation of response to drug(GO:2001025)
1.0 2.9 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.9 2.7 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.8 2.3 GO:1900736 regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736)
0.5 2.6 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.5 1.4 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.5 1.4 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.4 3.5 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.4 2.6 GO:0032811 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) negative regulation of epinephrine secretion(GO:0032811)
0.3 1.3 GO:0061428 positive regulation of oocyte development(GO:0060282) negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.3 1.3 GO:0009957 epidermal cell fate specification(GO:0009957)
0.3 1.4 GO:0030091 protein repair(GO:0030091)
0.3 0.8 GO:0097274 urea homeostasis(GO:0097274)
0.3 1.9 GO:0061042 vascular wound healing(GO:0061042)
0.2 1.5 GO:0097491 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491) neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.2 0.7 GO:0030827 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
0.2 1.7 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.2 1.0 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.2 0.6 GO:0009838 abscission(GO:0009838) positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.2 2.7 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.2 1.0 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.2 0.6 GO:0035106 operant conditioning(GO:0035106)
0.2 1.1 GO:0002317 plasma cell differentiation(GO:0002317) negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.2 1.2 GO:0007296 vitellogenesis(GO:0007296)
0.2 0.5 GO:0061743 motor learning(GO:0061743)
0.2 1.1 GO:0070458 detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.2 1.5 GO:0031424 keratinization(GO:0031424) establishment of skin barrier(GO:0061436)
0.1 0.3 GO:2000173 negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.1 3.1 GO:1903861 regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861)
0.1 0.7 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.1 2.3 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 0.8 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 0.9 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.1 0.3 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.1 0.5 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.1 0.5 GO:1901678 iron coordination entity transport(GO:1901678)
0.1 0.3 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582) regulation of sodium:potassium-exchanging ATPase activity(GO:1903406)
0.1 1.9 GO:1900452 regulation of long term synaptic depression(GO:1900452)
0.1 0.3 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743) alveolar secondary septum development(GO:0061144)
0.1 1.0 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 0.9 GO:0048484 enteric nervous system development(GO:0048484)
0.1 2.2 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.1 1.9 GO:2000811 negative regulation of anoikis(GO:2000811)
0.1 1.7 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.5 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.1 0.5 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.1 0.5 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 0.3 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 0.2 GO:0009405 pathogenesis(GO:0009405)
0.1 0.2 GO:0060854 patterning of lymph vessels(GO:0060854)
0.1 0.4 GO:0097531 mast cell migration(GO:0097531)
0.1 0.8 GO:0035646 endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.1 0.2 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 0.8 GO:0098743 cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.0 0.3 GO:0015862 uridine transport(GO:0015862)
0.0 6.9 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.0 1.0 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.5 GO:0048563 post-embryonic organ morphogenesis(GO:0048563)
0.0 0.3 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.0 0.2 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0 0.2 GO:0070234 positive regulation of T cell apoptotic process(GO:0070234)
0.0 0.4 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 1.6 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.7 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 0.7 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.0 0.4 GO:0042711 maternal behavior(GO:0042711)
0.0 0.6 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 2.9 GO:0045598 regulation of fat cell differentiation(GO:0045598)
0.0 1.5 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.7 GO:2000279 negative regulation of DNA biosynthetic process(GO:2000279)
0.0 0.2 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.7 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.0 GO:0042939 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.0 1.4 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.0 0.6 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.2 GO:0097186 amelogenesis(GO:0097186)
0.0 1.3 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.5 GO:0035115 embryonic forelimb morphogenesis(GO:0035115)
0.0 1.1 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.5 GO:0060351 cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.0 0.3 GO:0060065 uterus development(GO:0060065)
0.0 0.0 GO:1902861 copper ion import into cell(GO:1902861)
0.0 2.7 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.0 0.1 GO:0002457 T cell antigen processing and presentation(GO:0002457) histone H3-K4 demethylation(GO:0034720)
0.0 1.1 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
0.0 1.6 GO:0007369 gastrulation(GO:0007369)
0.0 0.3 GO:0048013 ephrin receptor signaling pathway(GO:0048013)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.7 GO:0032280 symmetric synapse(GO:0032280)
1.1 6.3 GO:1990635 proximal dendrite(GO:1990635)
0.5 2.6 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.4 1.7 GO:0005594 collagen type IX trimer(GO:0005594)
0.3 7.9 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.2 0.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.2 0.9 GO:0031084 BLOC-2 complex(GO:0031084)
0.2 1.3 GO:0033010 paranodal junction(GO:0033010)
0.2 1.4 GO:0033391 chromatoid body(GO:0033391)
0.1 1.1 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.1 0.3 GO:0035061 interchromatin granule(GO:0035061)
0.1 2.5 GO:0031430 M band(GO:0031430)
0.1 0.5 GO:0044301 climbing fiber(GO:0044301)
0.1 3.5 GO:0097440 apical dendrite(GO:0097440)
0.1 0.6 GO:0090543 Flemming body(GO:0090543)
0.1 0.5 GO:0002139 stereocilia coupling link(GO:0002139)
0.1 0.8 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 8.6 GO:0031225 anchored component of membrane(GO:0031225)
0.1 0.7 GO:0044327 dendritic spine head(GO:0044327)
0.1 1.0 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 3.2 GO:0005811 lipid particle(GO:0005811)
0.0 0.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 1.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.9 GO:0005871 kinesin complex(GO:0005871)
0.0 0.8 GO:0032590 dendrite membrane(GO:0032590)
0.0 2.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.2 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.3 GO:0005902 microvillus(GO:0005902)
0.0 1.8 GO:0005643 nuclear pore(GO:0005643)
0.0 0.3 GO:0031045 dense core granule(GO:0031045)
0.0 0.3 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 1.2 GO:0042734 presynaptic membrane(GO:0042734)
0.0 1.2 GO:0005581 collagen trimer(GO:0005581)
0.0 0.3 GO:0005605 basal lamina(GO:0005605)
0.0 0.6 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.7 GO:0045171 intercellular bridge(GO:0045171)
0.0 1.9 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 1.5 GO:0005903 brush border(GO:0005903)
0.0 2.4 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 2.6 GO:0043235 receptor complex(GO:0043235)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.2 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.7 2.6 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.4 1.3 GO:0005119 smoothened binding(GO:0005119) hedgehog receptor activity(GO:0008158) hedgehog family protein binding(GO:0097108)
0.4 2.6 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.3 1.3 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739) tubulin deacetylase activity(GO:0042903)
0.3 5.7 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.2 2.7 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.2 2.9 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.2 2.6 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.2 0.6 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.2 2.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.2 10.3 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 3.2 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 1.4 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 1.5 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.8 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 1.0 GO:0050815 phosphoserine binding(GO:0050815)
0.1 8.2 GO:0035064 methylated histone binding(GO:0035064)
0.1 0.5 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 1.4 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.1 3.9 GO:0045182 translation regulator activity(GO:0045182)
0.1 0.3 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 1.4 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.1 2.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 2.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 2.8 GO:0042169 SH2 domain binding(GO:0042169)
0.1 0.7 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 1.7 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 1.0 GO:0016917 GABA receptor activity(GO:0016917)
0.1 1.9 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 0.2 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.2 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.0 1.1 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 3.1 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.4 GO:0034711 inhibin binding(GO:0034711)
0.0 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 1.4 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 1.5 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.5 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 3.2 GO:0008201 heparin binding(GO:0008201)
0.0 1.1 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 1.5 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.0 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 3.2 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.9 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.9 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 0.6 GO:0004120 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.0 0.2 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)