Motif ID: Zkscan1

Z-value: 0.596


Transcription factors associated with Zkscan1:

Gene SymbolEntrez IDGene Name
Zkscan1 ENSMUSG00000029729.6 Zkscan1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zkscan1mm10_v2_chr5_+_138085083_138085147-0.282.0e-02Click!


Activity profile for motif Zkscan1.

activity profile for motif Zkscan1


Sorted Z-values histogram for motif Zkscan1

Sorted Z-values for motif Zkscan1



Network of associatons between targets according to the STRING database.



First level regulatory network of Zkscan1

PNG image of the network

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Top targets:


Showing 1 to 20 of 113 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_79164477 8.572 ENSMUST00000040019.4
 Sox10
SRY-box containing gene 10
chr4_-_42168603 4.564 ENSMUST00000098121.3
 Gm13305
predicted gene 13305
chr8_+_72646679 4.251 ENSMUST00000161386.1
ENSMUST00000093427.4
 Nwd1

NACHT and WD repeat domain containing 1

chr8_+_72646728 4.153 ENSMUST00000161254.1
 Nwd1
NACHT and WD repeat domain containing 1
chr4_+_129960760 4.125 ENSMUST00000139884.1
 1700003M07Rik
RIKEN cDNA 1700003M07 gene
chr2_-_156839790 3.828 ENSMUST00000134838.1
ENSMUST00000137463.1
ENSMUST00000149275.2
 Gm14230


predicted gene 14230


chr7_+_144896523 3.391 ENSMUST00000033389.5
 Fgf15
fibroblast growth factor 15
chr4_+_101419277 3.287 ENSMUST00000102780.1
ENSMUST00000106946.1
ENSMUST00000106945.1
 Ak4


adenylate kinase 4


chr9_+_98422961 3.128 ENSMUST00000052068.9
 Rbp1
retinol binding protein 1, cellular
chrX_+_20870166 3.103 ENSMUST00000115342.3
ENSMUST00000009530.4
 Timp1

tissue inhibitor of metalloproteinase 1

chr4_+_138972885 2.840 ENSMUST00000123636.1
ENSMUST00000043042.3
ENSMUST00000050949.2
 Tmco4


transmembrane and coiled-coil domains 4


chr13_-_53473074 2.838 ENSMUST00000021922.8
 Msx2
msh homeobox 2
chrX_-_49797700 2.467 ENSMUST00000033442.7
ENSMUST00000114891.1
 Igsf1

immunoglobulin superfamily, member 1

chr3_+_62338344 2.375 ENSMUST00000079300.6
 Arhgef26
Rho guanine nucleotide exchange factor (GEF) 26
chr2_-_27248335 2.336 ENSMUST00000139312.1
 Sardh
sarcosine dehydrogenase
chr7_-_118491912 2.304 ENSMUST00000178344.1
 Itpripl2
inositol 1,4,5-triphosphate receptor interacting protein-like 2
chr2_-_105399286 2.249 ENSMUST00000006128.6
 Rcn1
reticulocalbin 1
chr5_-_70842617 2.116 ENSMUST00000031119.1
 Gabrg1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
chr14_+_46832127 2.115 ENSMUST00000068532.8
 Cgrrf1
cell growth regulator with ring finger domain 1
chr19_-_45742873 2.011 ENSMUST00000026241.5
ENSMUST00000026240.7
ENSMUST00000111928.1
 Fgf8


fibroblast growth factor 8



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 47 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 8.6 GO:0048484 enteric nervous system development(GO:0048484)
0.4 5.2 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
1.0 5.0 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.8 3.4 GO:0070858 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.2 3.3 GO:0046033 AMP metabolic process(GO:0046033)
0.8 3.1 GO:0006776 vitamin A metabolic process(GO:0006776)
0.9 2.8 GO:0048818 embryonic nail plate morphogenesis(GO:0035880) positive regulation of hair follicle maturation(GO:0048818) positive regulation of catagen(GO:0051795) frontal suture morphogenesis(GO:0060364)
0.1 2.4 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.2 2.3 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.1 2.1 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.7 2.0 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.7 2.0 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.4 1.9 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.9 1.7 GO:0050883 musculoskeletal movement, spinal reflex action(GO:0050883)
0.1 1.6 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.3 1.5 GO:0070166 enamel mineralization(GO:0070166)
0.1 1.5 GO:0042711 maternal behavior(GO:0042711)
0.1 1.5 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.1 1.5 GO:0006693 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.1 1.3 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 26 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 8.6 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.1 6.2 GO:0005604 basement membrane(GO:0005604)
0.0 5.6 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 2.5 GO:0031225 anchored component of membrane(GO:0031225)
0.1 2.1 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 2.0 GO:0031143 pseudopodium(GO:0031143)
0.0 2.0 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 1.7 GO:0030139 endocytic vesicle(GO:0030139)
0.5 1.5 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.0 1.2 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.2 1.0 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 1.0 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 1.0 GO:0031526 brush border membrane(GO:0031526)
0.3 0.9 GO:1990075 stereocilia ankle link complex(GO:0002142) periciliary membrane compartment(GO:1990075)
0.0 0.8 GO:0005882 intermediate filament(GO:0005882)
0.2 0.7 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 0.7 GO:0005581 collagen trimer(GO:0005581)
0.1 0.6 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 0.6 GO:0001527 microfibril(GO:0001527)
0.0 0.6 GO:0031083 BLOC-1 complex(GO:0031083)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 38 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 8.6 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.1 5.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.4 5.0 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 3.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
1.1 3.3 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.5 3.1 GO:0019841 retinol binding(GO:0019841)
0.0 2.8 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.3 2.5 GO:0034711 inhibin binding(GO:0034711)
0.8 2.3 GO:0046997 sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.1 2.1 GO:0050811 GABA-A receptor activity(GO:0004890) GABA receptor binding(GO:0050811)
0.7 2.0 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 2.0 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.0 2.0 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.5 1.9 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.3 1.8 GO:0045703 pinocarveol dehydrogenase activity(GO:0018446) chloral hydrate dehydrogenase activity(GO:0018447) hydroxymethylmethylsilanediol oxidase activity(GO:0018448) 1-phenylethanol dehydrogenase activity(GO:0018449) myrtenol dehydrogenase activity(GO:0018450) cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene dehydrogenase activity(GO:0034522) 3-hydroxy-4-methyloctanoyl-CoA dehydrogenase activity(GO:0034582) 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA dehydrogenase activity(GO:0034778) cis-9,10-dihydroanthracene-9,10-diol dehydrogenase activity(GO:0034817) citronellol dehydrogenase activity(GO:0034821) naphthyl-2-hydroxymethyl-succinyl-CoA dehydrogenase activity(GO:0034847) 2,4,4-trimethyl-1-pentanol dehydrogenase activity(GO:0034863) 2,4,4-trimethyl-3-hydroxypentanoyl-CoA dehydrogenase activity(GO:0034868) 1-hydroxy-4,4-dimethylpentan-3-one dehydrogenase activity(GO:0034871) endosulfan diol dehydrogenase activity(GO:0034891) endosulfan hydroxyether dehydrogenase activity(GO:0034901) 3-hydroxy-2-methylhexanoyl-CoA dehydrogenase activity(GO:0034918) 3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase activity(GO:0034944) versicolorin reductase activity(GO:0042469) ketoreductase activity(GO:0045703)
0.6 1.7 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588) dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 1.6 GO:0035064 methylated histone binding(GO:0035064)
0.4 1.5 GO:0050436 microfibril binding(GO:0050436)
0.1 1.5 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.2 1.3 GO:0005173 stem cell factor receptor binding(GO:0005173)