Motif ID: Zscan4c

Z-value: 0.862


Transcription factors associated with Zscan4c:

Gene SymbolEntrez IDGene Name
Zscan4c ENSMUSG00000054272.5 Zscan4c



Activity profile for motif Zscan4c.

activity profile for motif Zscan4c


Sorted Z-values histogram for motif Zscan4c

Sorted Z-values for motif Zscan4c



Network of associatons between targets according to the STRING database.



First level regulatory network of Zscan4c

PNG image of the network

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Top targets:


Showing 1 to 20 of 86 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_55681257 17.025 ENSMUST00000044767.8
Neurod6
neurogenic differentiation 6
chr4_-_46991842 12.132 ENSMUST00000107749.2
Gabbr2
gamma-aminobutyric acid (GABA) B receptor, 2
chr8_+_118283719 11.456 ENSMUST00000117160.1
Cdh13
cadherin 13
chr4_+_49059256 10.139 ENSMUST00000076670.2
E130309F12Rik
RIKEN cDNA E130309F12 gene
chr15_-_78718113 9.042 ENSMUST00000088592.4
Elfn2
leucine rich repeat and fibronectin type III, extracellular 2
chr9_+_26733728 8.416 ENSMUST00000160899.1
ENSMUST00000161431.1
ENSMUST00000159799.1
B3gat1


beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)


chr9_-_49798905 7.844 ENSMUST00000114476.2
Ncam1
neural cell adhesion molecule 1
chr9_-_49798729 7.745 ENSMUST00000166811.2
Ncam1
neural cell adhesion molecule 1
chr3_-_158562199 7.660 ENSMUST00000106044.1
Lrrc7
leucine rich repeat containing 7
chr9_+_89909775 6.326 ENSMUST00000034912.4
ENSMUST00000034909.4
Rasgrf1

RAS protein-specific guanine nucleotide-releasing factor 1

chr13_+_58807884 6.154 ENSMUST00000079828.5
Ntrk2
neurotrophic tyrosine kinase, receptor, type 2
chr9_+_26733845 6.087 ENSMUST00000115269.2
B3gat1
beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)
chr5_-_44799643 5.425 ENSMUST00000070748.5
Ldb2
LIM domain binding 2
chr18_-_23041641 5.228 ENSMUST00000097651.3
Nol4
nucleolar protein 4
chr7_-_119184374 5.085 ENSMUST00000084650.4
Gpr139
G protein-coupled receptor 139
chr2_+_68861564 5.019 ENSMUST00000176018.1
Cers6
ceramide synthase 6
chr14_-_60177482 4.946 ENSMUST00000140924.1
Atp8a2
ATPase, aminophospholipid transporter-like, class I, type 8A, member 2
chr9_+_57940104 4.770 ENSMUST00000043059.7
Sema7a
sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A
chr7_-_47132698 4.411 ENSMUST00000033142.5
Ptpn5
protein tyrosine phosphatase, non-receptor type 5
chr2_+_68861433 4.318 ENSMUST00000028426.2
Cers6
ceramide synthase 6

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 43 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.9 17.0 GO:0021542 dentate gyrus development(GO:0021542)
5.2 15.6 GO:0001928 regulation of exocyst assembly(GO:0001928)
0.7 14.5 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.4 12.1 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
2.9 11.5 GO:0055095 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.1 11.5 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.2 9.3 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 7.1 GO:0010976 positive regulation of neuron projection development(GO:0010976)
0.7 6.7 GO:0007379 segment specification(GO:0007379)
0.1 6.6 GO:0008542 visual learning(GO:0008542)
0.4 6.3 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
1.0 6.2 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.7 4.9 GO:0061092 involuntary skeletal muscle contraction(GO:0003011) regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.8 4.8 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.9 4.4 GO:2001025 positive regulation of response to drug(GO:2001025)
1.4 4.1 GO:0002842 T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) positive regulation of T cell mediated immune response to tumor cell(GO:0002842) positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.7 4.0 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.5 3.8 GO:0097264 self proteolysis(GO:0097264)
0.5 3.7 GO:1905206 positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) positive regulation of hydrogen peroxide-induced cell death(GO:1905206)
0.5 3.2 GO:0045218 zonula adherens maintenance(GO:0045218)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 31.8 GO:0031225 anchored component of membrane(GO:0031225)
2.4 12.1 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.3 7.7 GO:0043194 axon initial segment(GO:0043194)
0.1 6.7 GO:0008023 transcription elongation factor complex(GO:0008023)
0.3 6.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.2 6.2 GO:0048786 presynaptic active zone(GO:0048786)
0.0 4.9 GO:0005802 trans-Golgi network(GO:0005802)
0.7 4.4 GO:1990635 proximal dendrite(GO:1990635)
0.4 4.1 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.3 3.2 GO:0005915 zonula adherens(GO:0005915)
0.2 2.9 GO:0032279 asymmetric synapse(GO:0032279)
0.0 2.6 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 2.4 GO:0008021 synaptic vesicle(GO:0008021)
0.6 2.3 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 2.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 2.1 GO:0043679 axon terminus(GO:0043679)
0.0 1.3 GO:0005604 basement membrane(GO:0005604)
0.3 1.2 GO:0031230 intrinsic component of cell outer membrane(GO:0031230) integral component of cell outer membrane(GO:0045203)
0.3 0.9 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 0.9 GO:0097440 apical dendrite(GO:0097440)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 45 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 20.4 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.8 15.6 GO:0030275 LRR domain binding(GO:0030275)
2.4 14.5 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
2.0 12.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
2.3 11.5 GO:0055100 adiponectin binding(GO:0055100)
1.0 9.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.2 9.0 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 6.9 GO:0008022 protein C-terminus binding(GO:0008022)
1.2 6.2 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 5.8 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.1 5.7 GO:0005246 calcium channel regulator activity(GO:0005246)
0.3 5.1 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.2 4.9 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.4 4.8 GO:0038191 neuropilin binding(GO:0038191)
0.2 4.4 GO:0001784 phosphotyrosine binding(GO:0001784)
0.3 4.1 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.2 4.0 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 3.7 GO:0001221 transcription cofactor binding(GO:0001221)
0.1 3.7 GO:0043015 gamma-tubulin binding(GO:0043015)
0.2 3.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)