Motif ID: Arid3a

Z-value: 0.672


Transcription factors associated with Arid3a:

Gene SymbolEntrez IDGene Name
Arid3a ENSMUSG00000019564.6 Arid3a

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Arid3amm10_v2_chr10_+_79927039_79927139-0.272.2e-01Click!


Activity profile for motif Arid3a.

activity profile for motif Arid3a


Sorted Z-values histogram for motif Arid3a

Sorted Z-values for motif Arid3a



Network of associatons between targets according to the STRING database.



First level regulatory network of Arid3a

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_85741389 3.230 ENSMUST00000094148.4
 Fam160a1
family with sequence similarity 160, member A1
chr15_-_3583191 2.733 ENSMUST00000069451.4
 Ghr
growth hormone receptor
chr7_+_66365905 2.261 ENSMUST00000107486.1
 Gm10974
predicted gene 10974
chr15_-_3583146 2.029 ENSMUST00000110698.2
 Ghr
growth hormone receptor
chr16_+_43510267 1.964 ENSMUST00000114695.2
 Zbtb20
zinc finger and BTB domain containing 20
chr3_-_116129615 1.859 ENSMUST00000029574.8
 Vcam1
vascular cell adhesion molecule 1
chr4_+_139923349 1.616 ENSMUST00000128563.1
 Gm13028
predicted gene 13028
chr5_-_70842617 1.566 ENSMUST00000031119.1
 Gabrg1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
chr4_-_87806296 1.462 ENSMUST00000126353.1
ENSMUST00000149357.1
 Mllt3

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3

chr4_-_87806276 1.458 ENSMUST00000148059.1
 Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chrX_-_141474034 1.371 ENSMUST00000101205.2
 Col4a6
collagen, type IV, alpha 6
chr17_+_3532554 1.345 ENSMUST00000168560.1
 Cldn20
claudin 20
chr11_-_80377975 1.031 ENSMUST00000179332.1
ENSMUST00000103225.4
ENSMUST00000134274.1
 5730455P16Rik


RIKEN cDNA 5730455P16 gene


chr7_+_140941550 0.935 ENSMUST00000079403.4
 Athl1
ATH1, acid trehalase-like 1 (yeast)
chr9_+_114731177 0.831 ENSMUST00000035007.8
 Cmtm6
CKLF-like MARVEL transmembrane domain containing 6
chr6_+_143285988 0.762 ENSMUST00000160951.1
 D6Ertd474e
DNA segment, Chr 6, ERATO Doi 474, expressed
chr2_+_3770673 0.749 ENSMUST00000177037.1
 Fam107b
family with sequence similarity 107, member B
chr17_-_78684262 0.747 ENSMUST00000145480.1
 Strn
striatin, calmodulin binding protein
chr12_-_4769217 0.728 ENSMUST00000053458.5
 Fam228b
family with sequence similarity 228, member B
chr18_+_35770318 0.695 ENSMUST00000165299.1
 Gm16490
predicted gene 16490
chr2_-_175327598 0.693 ENSMUST00000109050.2
 Gm4631
predicted gene 4631
chr1_+_179961110 0.659 ENSMUST00000076687.5
ENSMUST00000097450.3
 Cdc42bpa

CDC42 binding protein kinase alpha

chr4_+_58943575 0.605 ENSMUST00000107554.1
 Zkscan16
zinc finger with KRAB and SCAN domains 16
chr6_+_51544513 0.601 ENSMUST00000179365.1
ENSMUST00000114439.1
 Snx10

sorting nexin 10

chr15_-_50882806 0.525 ENSMUST00000184885.1
 Trps1
trichorhinophalangeal syndrome I (human)
chr17_+_40561498 0.489 ENSMUST00000167713.1
ENSMUST00000097324.3
 Gm5494
Gm5494
predicted gene 5494
predicted gene 5494
chr1_-_150392719 0.488 ENSMUST00000006167.6
ENSMUST00000094477.2
ENSMUST00000097547.3
 BC003331


cDNA sequence BC003331


chr2_-_32982007 0.467 ENSMUST00000028129.7
 Slc2a8
solute carrier family 2, (facilitated glucose transporter), member 8
chr11_-_116654245 0.446 ENSMUST00000021166.5
 Cygb
cytoglobin
chr3_-_146495115 0.400 ENSMUST00000093951.2
 Spata1
spermatogenesis associated 1
chr1_+_60181495 0.369 ENSMUST00000160834.1
 Nbeal1
neurobeachin like 1
chr11_+_87664274 0.362 ENSMUST00000092800.5
 Rnf43
ring finger protein 43
chr1_+_179960472 0.362 ENSMUST00000097453.2
ENSMUST00000111117.1
 Cdc42bpa

CDC42 binding protein kinase alpha

chr12_+_65225513 0.358 ENSMUST00000046331.4
 Wdr20b
WD repeat domain 20b
chr16_-_57292845 0.351 ENSMUST00000023434.8
ENSMUST00000120112.1
ENSMUST00000119407.1
 Tmem30c


transmembrane protein 30C


chr7_+_118597295 0.348 ENSMUST00000121715.1
ENSMUST00000098088.4
 Tmc5

transmembrane channel-like gene family 5

chr3_+_30602056 0.348 ENSMUST00000047502.7
 Mynn
myoneurin
chr9_+_54538984 0.343 ENSMUST00000060242.5
ENSMUST00000118413.1
 Sh2d7

SH2 domain containing 7

chr7_+_99594605 0.323 ENSMUST00000162290.1
 Arrb1
arrestin, beta 1
chr15_+_100334929 0.305 ENSMUST00000075420.4
 Mettl7a3
methyltransferase like 7A3
chr7_+_102223021 0.298 ENSMUST00000156529.1
ENSMUST00000138479.1
ENSMUST00000126914.1
ENSMUST00000033292.7
ENSMUST00000146559.1
 Pgap2




post-GPI attachment to proteins 2




chr10_-_100589205 0.295 ENSMUST00000054471.8
 4930430F08Rik
RIKEN cDNA 4930430F08 gene
chr10_+_69533803 0.266 ENSMUST00000182155.1
ENSMUST00000183169.1
ENSMUST00000183148.1
 Ank3


ankyrin 3, epithelial


chr7_+_27452417 0.260 ENSMUST00000108357.1
 Blvrb
biliverdin reductase B (flavin reductase (NADPH))
chr18_-_73754457 0.240 ENSMUST00000041138.2
 Elac1
elaC homolog 1 (E. coli)
chr6_+_29361410 0.232 ENSMUST00000156163.1
 Calu
calumenin
chr9_-_42457594 0.218 ENSMUST00000125995.1
 Tbcel
tubulin folding cofactor E-like
chr7_+_51878967 0.218 ENSMUST00000051912.6
 Gas2
growth arrest specific 2
chr6_-_131388417 0.216 ENSMUST00000032309.6
ENSMUST00000087865.2
 Ybx3

Y box protein 3

chr10_+_79996479 0.216 ENSMUST00000132517.1
 Abca7
ATP-binding cassette, sub-family A (ABC1), member 7
chr3_+_95282897 0.202 ENSMUST00000039537.7
ENSMUST00000107187.2
 Fam63a

family with sequence similarity 63, member A

chr12_+_4769375 0.199 ENSMUST00000178879.1
 Pfn4
profilin family, member 4
chr2_+_176807362 0.194 ENSMUST00000179435.1
 Gm14295
predicted gene 14295
chr3_+_32436376 0.193 ENSMUST00000108242.1
 Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr1_+_155158703 0.190 ENSMUST00000027743.7
 Stx6
syntaxin 6
chr7_-_121981669 0.186 ENSMUST00000057576.7
 Cog7
component of oligomeric golgi complex 7
chr7_+_51879041 0.180 ENSMUST00000107591.2
 Gas2
growth arrest specific 2
chrX_+_163911401 0.179 ENSMUST00000140845.1
 Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr1_+_17145357 0.177 ENSMUST00000026879.7
 Gdap1
ganglioside-induced differentiation-associated-protein 1
chr3_+_32436151 0.166 ENSMUST00000029201.7
 Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr2_-_176144697 0.151 ENSMUST00000178872.1
 Gm2004
predicted gene 2004
chr5_-_23616528 0.147 ENSMUST00000088392.4
 Srpk2
serine/arginine-rich protein specific kinase 2
chr15_+_83563571 0.144 ENSMUST00000047419.6
 Tspo
translocator protein
chr2_+_177009681 0.124 ENSMUST00000178182.1
 Gm14419
predicted gene 14419
chr1_+_150392794 0.123 ENSMUST00000124973.2
 Tpr
translocated promoter region
chr4_+_134930898 0.123 ENSMUST00000030622.2
 Syf2
SYF2 homolog, RNA splicing factor (S. cerevisiae)
chr12_+_69963452 0.115 ENSMUST00000110560.1
 Gm3086
predicted gene 3086
chr18_-_6241470 0.114 ENSMUST00000163210.1
 Kif5b
kinesin family member 5B
chr1_-_24612700 0.110 ENSMUST00000088336.1
 Gm10222
predicted gene 10222
chrX_+_162901226 0.104 ENSMUST00000101095.2
 Ctps2
cytidine 5'-triphosphate synthase 2
chr11_+_58199556 0.098 ENSMUST00000058704.8
ENSMUST00000035266.4
ENSMUST00000094169.4
ENSMUST00000168280.1
 Irgm2
Igtp


immunity-related GTPase family M member 2
interferon gamma induced GTPase


chr2_-_165388245 0.093 ENSMUST00000103084.3
 Zfp334
zinc finger protein 334
chr7_-_127376028 0.084 ENSMUST00000067425.4
 Zfp747
zinc finger protein 747
chrX_+_153237466 0.075 ENSMUST00000143880.1
 Klf8
Kruppel-like factor 8
chr10_-_127751707 0.074 ENSMUST00000079692.5
 Gpr182
G protein-coupled receptor 182
chr3_-_135608221 0.074 ENSMUST00000132668.1
 Nfkb1
nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
chr4_-_25281752 0.073 ENSMUST00000038705.7
 Ufl1
UFM1 specific ligase 1
chr10_-_58675631 0.070 ENSMUST00000003312.4
 Edar
ectodysplasin-A receptor
chr9_+_108392820 0.070 ENSMUST00000035234.4
 1700102P08Rik
RIKEN cDNA 1700102P08 gene
chr8_-_46080284 0.051 ENSMUST00000177186.1
 Snx25
sorting nexin 25
chr11_-_107348130 0.049 ENSMUST00000134763.1
 Pitpnc1
phosphatidylinositol transfer protein, cytoplasmic 1
chr10_+_69533761 0.039 ENSMUST00000182884.1
 Ank3
ankyrin 3, epithelial
chr1_+_171113918 0.037 ENSMUST00000129651.1
ENSMUST00000151340.1
 1700009P17Rik

RIKEN cDNA 1700009P17 gene

chr10_+_120227109 0.032 ENSMUST00000130198.1
 Llph
LLP homolog, long-term synaptic facilitation (Aplysia)
chr15_-_58847321 0.031 ENSMUST00000075109.5
 Ube2d4
ubiquitin-conjugating enzyme E2D 4
chr6_-_122856151 0.024 ENSMUST00000042081.8
 C3ar1
complement component 3a receptor 1
chr18_-_6241486 0.017 ENSMUST00000025083.7
 Kif5b
kinesin family member 5B
chr4_-_134552122 0.014 ENSMUST00000060435.6
 Sepn1
selenoprotein N, 1
chr10_-_13324250 0.013 ENSMUST00000105543.1
 Phactr2
phosphatase and actin regulator 2
chr10_-_13324160 0.008 ENSMUST00000105545.4
 Phactr2
phosphatase and actin regulator 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.8 GO:0000255 allantoin metabolic process(GO:0000255)
0.3 2.9 GO:0007379 segment specification(GO:0007379)
0.2 1.9 GO:0061032 visceral serous pericardium development(GO:0061032)
0.1 0.4 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 0.2 GO:1902219 regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902218) negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.1 1.4 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1 0.4 GO:0015671 oxygen transport(GO:0015671)
0.1 0.4 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 2.0 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 0.2 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.1 0.3 GO:0042167 heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.2 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.0 0.3 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393) follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 1.0 GO:0007097 nuclear migration(GO:0007097)
0.0 0.1 GO:0032240 RNA import into nucleus(GO:0006404) mRNA export from nucleus in response to heat stress(GO:0031990) negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.0 1.0 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.1 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.0 0.1 GO:0035617 stress granule disassembly(GO:0035617)
0.0 0.3 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.6 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.5 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.2 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.1 GO:1903416 negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137) regulation of calcidiol 1-monooxygenase activity(GO:0060558) response to glycoside(GO:1903416)
0.0 0.1 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.2 GO:0090161 Golgi ribbon formation(GO:0090161)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.1 0.4 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 0.6 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 0.9 GO:0030312 external encapsulating structure(GO:0030312)
0.1 1.6 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 1.9 GO:0002102 podosome(GO:0002102)
0.1 2.9 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.3 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 5.0 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 0.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.2 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 4.8 GO:0017046 peptide hormone binding(GO:0017046)
0.1 0.4 GO:0004096 catalase activity(GO:0004096)
0.1 0.3 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.1 1.6 GO:0050811 GABA-A receptor activity(GO:0004890) GABA receptor binding(GO:0050811)
0.1 0.2 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188)
0.1 0.3 GO:0004074 biliverdin reductase activity(GO:0004074)
0.0 0.4 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 0.9 GO:0044653 trehalase activity(GO:0015927) dextrin alpha-glucosidase activity(GO:0044653) starch alpha-glucosidase activity(GO:0044654) beta-glucanase activity(GO:0052736) beta-6-sulfate-N-acetylglucosaminidase activity(GO:0052769) glucan endo-1,4-beta-glucosidase activity(GO:0052859)
0.0 0.5 GO:0005536 glucose binding(GO:0005536)
0.0 0.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.7 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.1 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.1 GO:0071568 UFM1 transferase activity(GO:0071568)
0.0 0.1 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.0 0.0 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 2.0 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)