ISMARA results

ISMARA - Integrated System for Motif Actitivity Response Analysis is a free online tool that recognizes most important transcription factors that are changing their activity in a set of samples.

All motifs sorted by activity significance

Motif name Z-value Associated genes Profile Logo
Hdx 6.532 Hdx
Nfatc1 5.949 Nfatc1
Ybx1_Nfya_Nfyb_Nfyc_Cebpz 5.187 Ybx1
Nfya
Nfyb
Nfyc
Cebpz
Irf2_Irf1_Irf8_Irf9_Irf7 3.769 Irf2
Irf1
Irf8
Irf9
Irf7
Rfx3_Rfx1_Rfx4 3.675 Rfx3
Rfx1
Rfx4
Wrnip1_Mta3_Rcor1 3.604 Wrnip1
Mta3
Rcor1
Zfp110 3.488 Zfp110
Yy1_Yy2 3.211 Yy1
Yy2
Stat2 3.203 Stat2
Taf1 3.163 Taf1
Chd1_Pml 2.911 Chd1
Pml
Sp100 2.869 Sp100
Nrf1 2.594 Nrf1
Tbp 2.581 Tbp
Zfx_Zfp711 2.432 Zfx
Zfp711
Hoxb7 2.388 Hoxb7
E2f2_E2f5 2.361 E2f2
E2f5
Nfia 2.350 Nfia
Sp1 2.333 Sp1
Sox2 2.323 Sox2
Foxd1 2.310 Foxd1
Zbtb33_Chd2 2.283 Zbtb33
Chd2
Bptf 2.182 Bptf
Esr2 2.138 Esr2
Hcfc1_Six5_Smarcc2_Zfp143 2.081 Hcfc1
Six5
Smarcc2
Zfp143
E2f1 1.973 E2f1
Tfdp1_Wt1_Egr2 1.971 Tfdp1
Wt1
Egr2
Rest 1.951 Rest
Pou2f2_Pou3f1 1.843 Pou2f2
Pou3f1
Pax5 1.830 Pax5
Klf1 1.826 Klf1
Hic2 1.823 Hic2
Nfatc2 1.816 Nfatc2
Lef1 1.791 Lef1
Gcm2 1.782 Gcm2
Max_Mycn 1.749 Max
Mycn
Myf6 1.725 Myf6
Hoxd12 1.663 Hoxd12
Egr1 1.654 Egr1
Myb 1.645 Myb
Elf1_Elf2_Etv2_Elf4 1.634 Elf1
Elf2
Etv2
Elf4
Junb_Jund 1.604 Junb
Jund
Vsx2_Dlx3 1.596 Vsx2
Dlx3
Nkx2-2 1.591 Nkx2-2
Klf4_Sp3 1.587 Klf4
Sp3
Nfic_Nfib 1.561 Nfic
Nfib
Ppara 1.560 Ppara
Snai1_Zeb1_Snai2 1.557 Snai1
Zeb1
Snai2
Zfp219_Zfp740 1.554 Zfp219
Zfp740
Klf12_Klf14_Sp4 1.549 Klf12
Klf14
Sp4
Rhox4e_Rhox6_Vax2 1.497 Rhox4e
Rhox6
Vax2
Tead3_Tead4 1.486 Tead3
Tead4
Sox5_Sry 1.482 Sox5
Sry
Nfil3_Tef 1.466 Nfil3
Tef
Nfatc3 1.462 Nfatc3
Cpeb1 1.457 Cpeb1
Runx2_Bcl11a 1.457 Runx2
Bcl11a
Rela_Rel_Nfkb1 1.452 Rela
Rel
Nfkb1
Smad1 1.448 Smad1
Ahr 1.447 Ahr
Pitx2_Otx2 1.446 Pitx2
Otx2
Hnf4g 1.430 Hnf4g
Hoxb3 1.429 Hoxb3
Esrrb_Esrra 1.419 Esrrb
Esrra
Hmga2 1.412 Hmga2
Gtf2i_Gtf2f1 1.411 Gtf2i
Gtf2f1
Mybl2 1.407 Mybl2
Gata3 1.405 Gata3
Fli1 1.398 Fli1
Tfcp2 1.391 Tfcp2
Tcf21_Msc 1.387 Tcf21
Msc
Gfi1_Gfi1b 1.385 Gfi1
Gfi1b
Rarg 1.377 Rarg
Hic1 1.376 Hic1
Msx2_Hoxd4 1.376 Msx2
Nfix 1.373 Nfix
Foxj3_Tbl1xr1 1.372 Foxj3
Tbl1xr1
Hes1 1.357 Hes1
Epas1_Bcl3 1.356 Epas1
Bcl3
Cenpb 1.344 Cenpb
Foxi1_Foxo1 1.339 Foxi1
Foxo1
Hoxc13_Hoxd13 1.322
Mbd2 1.319 Mbd2
Ebf3 1.314 Ebf3
Nhlh1 1.287 Nhlh1
Ebf1 1.274 Ebf1
Ebf1
Onecut1_Cux2 1.273 Onecut1
Cux2
Cux2
Rfx2_Rfx7 1.268 Rfx2
Rfx7
Nfe2l1_Mafg 1.262 Nfe2l1
Mafg
Mafg
Tgif1_Meis3 1.262 Tgif1
Meis3
Pbx1_Pbx3 1.250 Pbx1
Pbx3
Hes5_Hes7 1.248 Hes5
Hes7
Creb1 1.244 Creb1
Hoxa1 1.240 Hoxa1
Cebpe 1.238 Cebpe
Foxq1 1.237 Foxq1
Mzf1 1.235 Mzf1
Dlx5_Dlx4 1.225 Dlx5
Dlx4
Ezh2_Atf2_Ikzf1 1.225 Ezh2
Atf2
Ikzf1
E2f7 1.225 E2f7
Erg 1.217 Erg
Etv1_Etv5_Gabpa 1.215 Etv1
Etv5
Gabpa
Prdm1 1.214 Prdm1
Glis2 1.206 Glis2
Xbp1_Creb3l1 1.200 Xbp1
Creb3l1
Sox3_Sox10 1.194 Sox3
Sox10
Spi1 1.191 Spi1
Hmbox1 1.166 Hmbox1
Srf 1.159 Srf
Zic4 1.154 Zic4
E2f3 1.153 E2f3
Foxo3 1.146 Foxo3
Hoxa2 1.144 Hoxa2
Nr1i3 1.144 Nr1i3
Sox14 1.142 Sox14
Mecp2 1.139 Mecp2
Sin3a 1.137 Sin3a
Zfp384 1.129 Zfp384
Nr1h2 1.126 Nr1h2
Mybl1 1.125 Mybl1
Zbtb16 1.124 Zbtb16
Zbtb18 1.109 Zbtb18
Tbx4 1.109 Tbx4
Hoxa11_Hoxc12 1.091 Hoxa11
Hoxc12
Dmc1 1.082 Dmc1
Tfeb_Usf1_Srebf1_Usf2_Bhlhe41_Srebf2 1.077 Tfeb
Usf1
Srebf1
Usf2
Bhlhe41
Srebf2
Tbx1_Eomes 1.070 Tbx1
Eomes
Mtf1 1.066 Mtf1
Ets1 1.065 Ets1
Pou5f1 1.052 Pou5f1
Gli2 1.044 Gli2
Maz_Zfp281 1.035 Maz
Zfp281
Zbtb14 1.034 Zbtb14
Onecut2_Onecut3 1.033 Onecut2
Onecut3
Hmga1 1.031 Hmga1
Esr1 1.031 Esr1
Prop1 1.029 Prop1
Tcf4_Mesp1 1.028 Tcf4
Mesp1
Irf3 1.028 Irf3
Tcf7l1 1.021 Tcf7l1
Hoxc9 1.016 Hoxc9
Zbtb6 1.015 Zbtb6
Msx1_Lhx9_Barx1_Rax_Dlx6 1.014 Msx1
Lhx9
Barx1
Rax
Dlx6
Vsx1_Uncx_Prrx2_Shox2_Noto 1.011 Vsx1
Uncx
Prrx2
Shox2
Noto
Pou1f1 1.003 Pou1f1
Tfap2b 1.001 Tfap2b
Rbpj 0.999 Rbpj
Gmeb2 0.998 Gmeb2
Nr2f2 0.997 Nr2f2
Hand1 0.989 Hand1
Ubp1 0.984 Ubp1
Stat5a 0.983 Stat5a
Trp53 0.979 Trp53
Hivep1 0.978 Hivep1
Tbr1 0.970 Tbr1
Tfap2c 0.969 Tfap2c
Foxa3 0.967 Foxa3
Pparg_Rxrg 0.961 Pparg
Rxrg
Hinfp 0.957 Hinfp
Klf16_Sp8 0.957 Klf16
Sp8
Hoxa5 0.955 Hoxa5
Stat4_Stat3_Stat5b 0.952 Stat4
Stat3
Stat5b
Klf15 0.950 Klf15
Tfap2e 0.947 Tfap2e
Foxb1 0.936 Foxb1
Tbx5 0.936 Tbx5
Isl2 0.936 Isl2
Klf6_Patz1 0.933 Klf6
Patz1
Tfap2d 0.928 Tfap2d
Hnf4a 0.927 Hnf4a
Pknox2_Pknox1 0.924 Pknox2
Pknox1
Vdr 0.919 Vdr
Tal1 0.912 Tal1
Tcf7_Tcf7l2 0.911 Tcf7
Tcf7l2
Zbtb7a 0.911 Zbtb7a
Dlx1 0.910 Dlx1
Hoxd11_Cdx1_Hoxc11 0.909 Hoxd11
Cdx1
Hoxc11
Prrx1_Isx_Prrxl1 0.905 Prrx1
Isx
Prrxl1
Hoxa4 0.905 Hoxa4
Tfap4 0.902 Tfap4
Spic 0.898 Spic
Nr5a2 0.896 Nr5a2
Runx1 0.894 Runx1
Zic3 0.887 Zic3
Gli1 0.886 Gli1
Ets2 0.884 Ets2
Pax2 0.883 Pax2
Foxm1 0.874 Foxm1
Zbtb7c 0.872 Zbtb7c
Scrt2 0.869 Scrt2
Hoxd1 0.865 Hoxd1
Nr1i2 0.864 Nr1i2
Atf7_E4f1 0.863 Atf7
Atf7
E4f1
E2f4 0.859 E2f4
Irf5_Irf6 0.855 Irf5
Irf6
Foxa2_Foxa1 0.852 Foxa2
Foxa1
Zfp652 0.850 Zfp652
Nkx2-3 0.849 Nkx2-3
Fubp1 0.848 Fubp1
Atf3 0.844 Atf3
Tfap2a 0.841 Tfap2a
Twist1 0.839 Twist1
Sox4 0.839 Sox4
Elf3 0.835 Elf3
Pou6f2_Pou4f2 0.834 Pou6f2
Pou4f2
Zfp148 0.834 Zfp148
Hey2 0.828 Hey2
Pitx3 0.828 Pitx3
Hoxa13 0.825 Hoxa13
Six3_Six1_Six2 0.825 Six3
Six1
Six2
Rreb1 0.823 Rreb1
Hey1_Myc_Mxi1 0.822 Hey1
Myc
Mxi1
Foxc1 0.822 Foxc1
Sox6_Sox9 0.822 Sox6
Sox9
Meis2 0.819 Meis2
Hoxb13 0.810 Hoxb13
Tlx2 0.810 Tlx2
Zfhx3 0.806 Zfhx3
Foxd2 0.804 Foxd2
Zbtb7b 0.802 Zbtb7b
Atf6 0.801 Atf6
Hsf2 0.800 Hsf2
Ikzf2 0.800 Ikzf2
Osr2_Osr1 0.800 Osr2
Osr1
Tgif2_Tgif2lx1_Tgif2lx2 0.800 Tgif2
Tgif2lx1
Tgif2lx2
Gli3_Zic1 0.799 Gli3
Zic1
Dbp 0.795 Dbp
Foxo4 0.788 Foxo4
Foxp1_Foxj2 0.787 Foxp1
Foxj2
Egr3 0.786 Egr3
Ar 0.781 Ar
Nfe2_Bach1_Mafk 0.778 Nfe2
Bach1
Mafk
Nr1h4 0.775 Nr1h4
Obox6_Obox5 0.762 Obox6
Obox5
Nfat5 0.762 Nfat5
Meox1 0.761 Meox1
Pou3f2 0.759 Pou3f2
Etv3_Erf_Fev_Elk4_Elk1_Elk3 0.758 Etv3
Erf
Fev
Elk4
Elk1
Elk3
Smarcc1_Fosl1 0.758 Smarcc1
Fosl1
Lhx2_Hoxc5 0.757 Lhx2
Hoxc5
Irx6_Irx2_Irx3 0.756 Irx6
Irx2
Irx3
Rad21_Smc3 0.749 Rad21
Smc3
Tbx19 0.748 Tbx19
Mef2c 0.742 Mef2c
Spib 0.742 Spib
Gata5 0.742 Gata5
Hoxc4_Arx_Otp_Esx1_Phox2b 0.739 Hoxc4
Arx
Otp
Esx1
Phox2b
Relb 0.738 Relb
Smad3 0.736 Smad3
Nr2c2 0.733 Nr2c2
Rara 0.729 Rara
Hlf 0.728 Hlf
Hoxa10 0.727 Hoxa10
Cebpb 0.727 Cebpb
Mnt 0.718 Mnt
Sox18_Sox12 0.717 Sox18
Sox12
Six4 0.713 Six4
Tfcp2l1 0.713 Tfcp2l1
Arntl_Tfe3_Mlx_Mitf_Mlxipl_Tfec 0.713 Arntl
Tfe3
Mlx
Mitf
Mlxipl
Tfec
Id4 0.711 Id4
Irf4 0.708 Irf4
Lhx8 0.705 Lhx8
Foxc2 0.704 Foxc2
Pou4f1_Pou6f1 0.704 Pou4f1
Pou6f1
Homez 0.702 Homez
Atf5 0.701 Atf5
Pitx1 0.701 Pitx1
Mef2b 0.700 Mef2b
Elf5 0.699 Elf5
Maf_Nrl 0.698 Maf
Nrl
Mafb 0.696 Mafb
Atf4 0.691 Atf4
Nkx1-1_Nkx1-2 0.689 Nkx1-1
Nkx1-2
Zic2 0.688 Zic2
En2 0.688 En2
En1 0.686 En1
Ctcfl_Ctcf 0.681 Ctcfl
Ctcf
T 0.679 T
Hoxa6 0.678 Hoxa6
Nr2f6 0.678 Nr2f6
Foxd3 0.677 Foxd3
Fos 0.677 Fos
Hoxb5 0.675 Hoxb5
Pou2f1 0.674 Pou2f1
Plag1 0.673 Plag1
Arid3a 0.672 Arid3a
Irx5 0.671 Irx5
Stat6 0.671 Stat6
Arnt 0.671 Arnt
Gata4 0.669 Gata4
Neurod1 0.669 Neurod1
Alx4 0.669 Alx4
E2f6 0.666 E2f6
Zbtb4 0.666 Zbtb4
Meox2 0.665 Meox2
Hoxb8_Pdx1 0.663 Hoxb8
Pdx1
Bcl6b 0.656 Bcl6b
Nkx3-2 0.654 Nkx3-2
Nkx6-1_Evx1_Hesx1 0.653 Nkx6-1
Evx1
Hesx1
Tbx15 0.648 Tbx15
Bcl6 0.646 Bcl6
Nr2e3 0.645 Nr2e3
Emx1_Emx2 0.644 Emx1
Emx2
Meis1 0.641 Meis1
Hmx1 0.638 Hmx1
Egr4 0.637 Egr4
Mef2d_Mef2a 0.636 Mef2d
Mef2a
Foxp2_Foxp3 0.635 Foxp2
Foxp3
Ascl2 0.631 Ascl2
Myod1 0.629 Myod1
Cux1 0.629 Cux1
Sox21 0.629 Sox21
Zfp263 0.628 Zfp263
Mecom 0.627 Mecom
Foxf1 0.626 Foxf1
Foxf2 0.626 Foxf2
Gsc2_Dmbx1 0.626 Gsc2
Dmbx1
Hbp1 0.624 Hbp1
Thra 0.622 Thra
Nr2f1_Nr4a1 0.622 Nr2f1
Nr4a1
Pgr_Nr3c1 0.621 Pgr
Nr3c1
Ep300 0.620 Ep300
Zfp784 0.618 Zfp784
Pou2f3 0.617 Pou2f3
Hif1a 0.615 Hif1a
Lhx3 0.610 Lhx3
Aire 0.609 Aire
Lhx4 0.609 Lhx4
Obox1 0.607 Obox1
Spdef 0.604 Spdef
Figla 0.603 Figla
Hoxb2_Dlx2 0.599 Hoxb2
Dlx2
Nr4a3 0.599 Nr4a3
Zfp105 0.599 Zfp105
Hsf4 0.595 Hsf4
Mnx1_Lhx6_Lmx1a 0.595 Mnx1
Lhx6
Lmx1a
Glis3 0.591 Glis3
Glis3
Runx3 0.590 Runx3
Fosl2_Bach2 0.587 Fosl2
Bach2
Hoxd9 0.587 Hoxd9
Klf8 0.585 Klf8
Etv6 0.585 Etv6
Cdx2 0.582 Cdx2
Tlx1 0.577 Tlx1
Scrt1 0.577 Scrt1
Creb3 0.576 Creb3
Zscan4c 0.572 Zscan4c
Gbx2 0.570 Gbx2
Nr4a2 0.568 Nr4a2
Hoxa3 0.566 Hoxa3
Hsfy2 0.564 Hsfy2
Pou3f4 0.563 Pou3f4
Nkx6-2 0.563 Nkx6-2
Nkx6-3_Dbx2_Barx2 0.563 Nkx6-3
Dbx2
Barx2
Tcf3 0.560 Tcf3
Rxrb 0.559 Rxrb
Nanog 0.559 Nanog
Hoxa7_Hoxc8 0.559 Hoxa7
Hoxc8
Olig2_Olig3 0.559 Olig2
Olig3
Nr2c1 0.558 Nr2c1
Barhl2 0.555 Barhl2
Hoxd8 0.555 Hoxd8
Klf7 0.554 Klf7
Batf 0.553 Batf
Gsx1_Alx1_Mixl1_Lbx2 0.552 Gsx1
Alx1
Mixl1
Lbx2
Cdc5l 0.550 Cdc5l
Hoxc10 0.549 Hoxc10
Sox7 0.548 Sox7
Trp73 0.547 Trp73
Nkx2-1 0.547 Nkx2-1
Smad4 0.545 Smad4
Bsx 0.544 Bsx
Pax6 0.544 Pax6
Gata2_Gata1 0.544 Gata2
Gata1
Stat1 0.543 Stat1
Brca1 0.541 Brca1
Pbx2 0.538 Pbx2
Mafa 0.536 Mafa
Nfe2l2 0.533 Nfe2l2
Sp2 0.532 Sp2
Atf1_Creb5 0.530 Atf1
Creb5
Nr3c2 0.529 Nr3c2
Zfp423 0.526 Zfp423
Tbx21 0.526 Tbx21
Pax4 0.523 Pax4
Hoxb1 0.522 Hoxb1
Zfp524 0.517 Zfp524
Trp63 0.516 Trp63
Ptf1a 0.514 Ptf1a
Sox17 0.507 Sox17
Klf13 0.506 Klf13
Hnf1a 0.504 Hnf1a
Clock 0.504 Clock
Prox1 0.504 Prox1
Foxg1 0.500 Foxg1
Tbx2 0.498 Tbx2
Crem_Jdp2 0.497 Crem
Jdp2
Ddit3 0.495 Ddit3
Bhlhe40 0.494 Bhlhe40
Nkx2-4 0.491 Nkx2-4
Rorc_Nr1d1 0.491 Rorc
Nr1d1
Foxl1 0.490 Foxl1
Foxl1
Thrb 0.484 Thrb
Myog_Tcf12 0.482 Myog
Tcf12
Maff 0.482 Maff
Lhx5_Lmx1b_Lhx1 0.481 Lhx5
Lmx1b
Lhx1
Hsf1 0.479 Hsf1
Nkx3-1 0.478 Nkx3-1
Cebpa_Cebpg 0.477 Cebpa
Cebpg
Gcm1 0.477 Gcm1
Nr6a1 0.475 Nr6a1
Cxxc1 0.475 Cxxc1
Hnf1b 0.474 Hnf1b
Pax7 0.474 Pax7
Rxra 0.473 Rxra
Hmx2 0.473 Hmx2
Gbx1_Nobox_Alx3 0.470 Gbx1
Nobox
Alx3
Barhl1 0.470 Barhl1
Nkx2-5 0.470 Nkx2-5
Foxn1 0.466 Foxn1
Nfkb2 0.465 Nfkb2
Neurod2_Bhlha15_Bhlhe22_Olig1 0.461 Neurod2
Bhlha15
Bhlhe22
Olig1
Rora 0.461 Rora
Zbtb3 0.461 Zbtb3
Atoh1_Bhlhe23 0.460 Atoh1
Bhlhe23
Foxk1_Foxj1 0.459 Foxk1
Foxj1
E2f8 0.459 E2f8
Gsx2_Hoxd3_Vax1 0.451 Gsx2
Hoxd3
Vax1
Sox11 0.448 Sox11
Zfp282 0.448 Zfp282
Six6 0.448 Six6
Jun 0.447 Jun
Nr0b1 0.447 Nr0b1
Grhl1 0.447 Grhl1
Isl1 0.445 Isl1
Hoxa9_Hoxb9 0.444 Hoxa9
Hoxb9
Nkx2-9 0.444 Nkx2-9
Etv4 0.441 Etv4
Zfp691 0.437 Zfp691
Sox13 0.435 Sox13
Sox15 0.433 Sox15
Zkscan1 0.432 Zkscan1
Hmx3 0.424 Hmx3
Hoxd10 0.424 Hoxd10
Cebpd 0.423 Cebpd
Tead1 0.422 Tead1
Creb3l2 0.419 Creb3l2
Sox8 0.417 Sox8
Plagl1 0.417 Plagl1
Fosb 0.416 Fosb
Zbtb12 0.395 Zbtb12
Nfatc4 0.391 Nfatc4
Batf3 0.390 Batf3
Rfx5 0.383 Rfx5
Neurog2 0.382 Neurog2
Pax8 0.378 Pax8
Mga 0.378 Mga
Zkscan3 0.377 Zkscan3
Phox2a 0.375 Phox2a
Gmeb1 0.366 Gmeb1
Insm1 0.364 Insm1
Prdm14 0.362 Prdm14
Zfp128 0.362 Zfp128
Foxo6 0.362 Foxo6
Evx2 0.360 Evx2
Msx3 0.353 Msx3
Sox1 0.353 Sox1
Smad2 0.352 Smad2
Otx1 0.347 Otx1
Rarb 0.347 Rarb
Gata6 0.342 Gata6
Obox3 0.339 Obox3
Hoxc6 0.338 Hoxc6
Pax3 0.338 Pax3
Rhox11 0.335 Rhox11
Klf3 0.334 Klf3
Sox30 0.330 Sox30
Nr2e1 0.327 Nr2e1
Gzf1 0.324 Gzf1
Prdm4 0.324 Prdm4
Crx_Gsc 0.315 Crx
Gsc
Tbx20 0.314 Tbx20
Hoxb4 0.313 Hoxb4
Esrrg 0.304 Esrrg
Ppard 0.294 Ppard
Arnt2 0.294 Arnt2
Pax1_Pax9 0.288 Pax1
Pax9
Pou4f3 0.283 Pou4f3
Hlx 0.269 Hlx
Hoxb6 0.267 Hoxb6
Tbx3 0.265 Tbx3
Arid5b 0.249 Arid5b
Cbfb 0.246 Cbfb
Arid5a 0.235 Arid5a
Irx4 0.234 Irx4
Zfp410 0.228 Zfp410
Ehf 0.222 Ehf
Pou3f3 0.209 Pou3f3
Zbtb49 0.207 Zbtb49
Bbx 0.204 Bbx
Nkx2-6 0.191 Nkx2-6
Ovol1 0.190 Ovol1
Glis1 0.091 Glis1

All samples sorted alphabetically


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Sample name Condition Replicate/Batch
E125_BP_WT_1
E125_BP_WT_2
E125_BP_WT_3
E135_BP_WT_1
E135_BP_WT_2
E135_BP_WT_3
E145_BP_WT_1
E145_BP_WT_2
E145_BP_WT_3
E155_BP_WT_1
E155_BP_WT_2
E155_BP_WT_3
E155_BP_WT_4
E165_BP_WT_1
E165_BP_WT_2
E165_BP_WT_3
E175_BP_WT_1
E175_BP_WT_2
E185_BP_WT_1
E185_BP_WT_2
E185_BP_WT_3
PN_BP_WT_1
PN_BP_WT_2