Motif ID: Hoxa5

Z-value: 0.955


Transcription factors associated with Hoxa5:

Gene SymbolEntrez IDGene Name
Hoxa5 ENSMUSG00000038253.6 Hoxa5



Activity profile for motif Hoxa5.

activity profile for motif Hoxa5


Sorted Z-values histogram for motif Hoxa5

Sorted Z-values for motif Hoxa5



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa5

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_17574268 4.539 ENSMUST00000030568.7
 Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr5_+_17574726 3.070 ENSMUST00000169603.1
 Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr16_+_43508118 3.016 ENSMUST00000114690.1
 Zbtb20
zinc finger and BTB domain containing 20
chrX_+_66653003 2.851 ENSMUST00000036043.4
 Slitrk2
SLIT and NTRK-like family, member 2
chr9_-_58313189 2.487 ENSMUST00000061799.8
 Loxl1
lysyl oxidase-like 1
chr5_+_3343893 1.950 ENSMUST00000165117.1
 Cdk6
cyclin-dependent kinase 6
chr1_+_169655493 1.880 ENSMUST00000027997.3
 Rgs5
regulator of G-protein signaling 5
chr16_+_43247278 1.833 ENSMUST00000114691.1
ENSMUST00000079441.6
 Zbtb20

zinc finger and BTB domain containing 20

chr3_+_62419668 1.814 ENSMUST00000161057.1
 Arhgef26
Rho guanine nucleotide exchange factor (GEF) 26
chr8_-_99416397 1.628 ENSMUST00000155527.1
ENSMUST00000142129.1
ENSMUST00000093249.4
ENSMUST00000142475.2
ENSMUST00000128860.1
 Cdh8




cadherin 8




chrY_+_1010543 1.534 ENSMUST00000091197.3
 Eif2s3y
eukaryotic translation initiation factor 2, subunit 3, structural gene Y-linked
chrY_-_1286563 1.527 ENSMUST00000091190.5
 Ddx3y
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chr4_+_128846163 1.503 ENSMUST00000138291.1
 Gm12968
predicted gene 12968
chr3_-_116968969 1.500 ENSMUST00000143611.1
ENSMUST00000040097.7
 Palmd

palmdelphin

chr15_-_98677451 1.343 ENSMUST00000120997.1
ENSMUST00000109149.2
ENSMUST00000003451.4
 Rnd1


Rho family GTPase 1


chr17_-_81649607 1.321 ENSMUST00000163680.2
ENSMUST00000086538.3
ENSMUST00000163123.1
 Slc8a1


solute carrier family 8 (sodium/calcium exchanger), member 1


chr11_+_16752203 1.319 ENSMUST00000102884.3
ENSMUST00000020329.6
 Egfr

epidermal growth factor receptor

chr5_-_62766153 1.279 ENSMUST00000076623.4
 Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr1_+_104768510 1.278 ENSMUST00000062528.8
 Cdh20
cadherin 20
chr6_+_103510874 1.277 ENSMUST00000066905.6
 Chl1
cell adhesion molecule with homology to L1CAM

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 187 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.2 8.5 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 4.9 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 2.9 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 2.9 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 2.6 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 2.1 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 2.0 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.6 1.9 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.1 1.6 GO:0009409 response to cold(GO:0009409)
0.1 1.5 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 1.5 GO:0035640 exploration behavior(GO:0035640)
0.3 1.3 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.3 1.3 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 1.3 GO:0016322 neuron remodeling(GO:0016322)
0.0 1.3 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 1.2 GO:0034113 heterotypic cell-cell adhesion(GO:0034113)
0.2 1.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1 1.1 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.3 1.0 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.3 1.0 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 77 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.5 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 1.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 1.9 GO:0043198 dendritic shaft(GO:0043198)
0.0 1.8 GO:0005923 bicellular tight junction(GO:0005923)
0.0 1.7 GO:0043197 dendritic spine(GO:0043197)
0.1 1.6 GO:0043083 synaptic cleft(GO:0043083)
0.0 1.6 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 1.6 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.4 1.3 GO:0031983 vesicle lumen(GO:0031983)
0.0 1.3 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.4 1.2 GO:0005927 muscle tendon junction(GO:0005927)
0.1 1.2 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 1.1 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 1.1 GO:0036126 sperm flagellum(GO:0036126)
0.0 1.0 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 1.0 GO:0035861 site of double-strand break(GO:0035861)
0.3 0.9 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.2 0.8 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0 0.8 GO:0031201 SNARE complex(GO:0031201)
0.1 0.7 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 117 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 8.5 GO:0038191 neuropilin binding(GO:0038191)
0.0 5.7 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.8 2.5 GO:0043912 D-lysine oxidase activity(GO:0043912)
0.1 2.1 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 2.0 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 1.9 GO:0030332 cyclin binding(GO:0030332)
0.0 1.8 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 1.5 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.4 1.3 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.3 1.3 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.0 1.2 GO:0043236 laminin binding(GO:0043236)
0.0 1.2 GO:0005504 fatty acid binding(GO:0005504)
0.0 1.2 GO:0003743 translation initiation factor activity(GO:0003743)
0.3 1.1 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.1 1.1 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 1.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.3 1.0 GO:0098809 nitrite reductase activity(GO:0098809)
0.3 1.0 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.1 1.0 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 1.0 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)