Motif ID: Cdx2

Z-value: 0.582


Transcription factors associated with Cdx2:

Gene SymbolEntrez IDGene Name
Cdx2 ENSMUSG00000029646.3 Cdx2



Activity profile for motif Cdx2.

activity profile for motif Cdx2


Sorted Z-values histogram for motif Cdx2

Sorted Z-values for motif Cdx2



Network of associatons between targets according to the STRING database.



First level regulatory network of Cdx2

PNG image of the network

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Top targets:


Showing 1 to 20 of 43 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_186705980 3.259 ENSMUST00000045288.8
 Tgfb2
transforming growth factor, beta 2
chr4_+_144893127 3.165 ENSMUST00000142808.1
 Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr4_-_64046925 2.704 ENSMUST00000107377.3
 Tnc
tenascin C
chr12_+_85473883 2.397 ENSMUST00000021674.6
 Fos
FBJ osteosarcoma oncogene
chr15_+_3270767 2.154 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
 Sepp1



selenoprotein P, plasma, 1



chr14_+_80000292 1.914 ENSMUST00000088735.3
 Olfm4
olfactomedin 4
chr16_-_44016387 1.831 ENSMUST00000036174.3
 Gramd1c
GRAM domain containing 1C
chr4_-_24430838 1.766 ENSMUST00000183964.1
 RP23-35K5.2
RP23-35K5.2
chr2_+_4300462 1.474 ENSMUST00000175669.1
 Frmd4a
FERM domain containing 4A
chr5_+_13399309 1.455 ENSMUST00000030714.7
ENSMUST00000141968.1
 Sema3a

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A

chr3_+_118433797 1.280 ENSMUST00000180593.1
ENSMUST00000181926.1
ENSMUST00000181060.1
ENSMUST00000181310.1
 Gm26871



predicted gene, 26871



chr6_+_17491216 1.105 ENSMUST00000080469.5
 Met
met proto-oncogene
chr3_+_88965812 0.998 ENSMUST00000090933.4
 Ash1l
ash1 (absent, small, or homeotic)-like (Drosophila)
chr13_+_63282142 0.962 ENSMUST00000159152.1
 2010111I01Rik
RIKEN cDNA 2010111I01 gene
chr2_-_59948155 0.944 ENSMUST00000153136.1
 Baz2b
bromodomain adjacent to zinc finger domain, 2B
chr11_+_87663087 0.630 ENSMUST00000165679.1
 Rnf43
ring finger protein 43
chr1_-_163289214 0.584 ENSMUST00000183691.1
 Prrx1
paired related homeobox 1
chr1_+_12692430 0.538 ENSMUST00000180062.1
ENSMUST00000177608.1
 Sulf1

sulfatase 1

chr12_-_102878406 0.526 ENSMUST00000045652.6
 Btbd7
BTB (POZ) domain containing 7
chr18_+_37755718 0.525 ENSMUST00000061279.7
 Pcdhga9
protocadherin gamma subfamily A, 9

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 3.3 GO:0048818 positive regulation of hair follicle maturation(GO:0048818) positive regulation of catagen(GO:0051795) regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905005)
0.3 3.2 GO:0042572 retinol metabolic process(GO:0042572)
0.7 2.7 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.1 2.4 GO:0035994 response to muscle stretch(GO:0035994)
0.3 2.2 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 1.9 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.3 1.5 GO:0021856 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) facioacoustic ganglion development(GO:1903375)
0.0 1.5 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 1.1 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 1.0 GO:0002674 negative regulation of acute inflammatory response(GO:0002674)
0.0 1.0 GO:0043171 peptide catabolic process(GO:0043171)
0.1 0.6 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.6 GO:0048664 neuron fate determination(GO:0048664)
0.1 0.5 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.5 GO:1903887 motile primary cilium assembly(GO:1903887)
0.1 0.5 GO:0060693 regulation of branching involved in salivary gland morphogenesis(GO:0060693)
0.0 0.5 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 0.4 GO:1900275 negative regulation of phospholipase C activity(GO:1900275)
0.1 0.4 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.3 GO:0030263 apoptotic chromosome condensation(GO:0030263)

Gene overrepresentation in cellular_component category:

Showing 1 to 8 of 8 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.3 GO:0005604 basement membrane(GO:0005604)
0.2 2.7 GO:0005614 interstitial matrix(GO:0005614)
0.0 2.5 GO:0005923 bicellular tight junction(GO:0005923)
0.1 1.9 GO:0042581 specific granule(GO:0042581)
0.0 1.4 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.5 GO:0034707 chloride channel complex(GO:0034707)
0.1 0.4 GO:1990037 Lewy body core(GO:1990037)
0.0 0.3 GO:0061574 ASAP complex(GO:0061574)

Gene overrepresentation in molecular_function category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 3.3 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.5 3.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.5 2.7 GO:0045545 syndecan binding(GO:0045545)
0.1 2.4 GO:0070412 R-SMAD binding(GO:0070412)
0.1 2.2 GO:0008430 selenium binding(GO:0008430)
0.0 2.2 GO:0045296 cadherin binding(GO:0045296)
0.1 1.5 GO:0038191 neuropilin binding(GO:0038191)
0.0 1.5 GO:0030674 protein binding, bridging(GO:0030674)
0.3 1.1 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.2 1.0 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 1.0 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.6 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.6 GO:0005109 frizzled binding(GO:0005109)
0.1 0.5 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.5 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.4 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.2 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)