Motif ID: Clock

Z-value: 0.504


Transcription factors associated with Clock:

Gene SymbolEntrez IDGene Name
Clock ENSMUSG00000029238.8 Clock

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Clockmm10_v2_chr5_-_76304474_76304548-0.039.0e-01Click!


Activity profile for motif Clock.

activity profile for motif Clock


Sorted Z-values histogram for motif Clock

Sorted Z-values for motif Clock



Network of associatons between targets according to the STRING database.



First level regulatory network of Clock

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_139543889 1.545 ENSMUST00000174792.1
ENSMUST00000031523.8
Uncx

UNC homeobox

chr7_-_144939823 1.288 ENSMUST00000093962.4
Ccnd1
cyclin D1
chr6_-_49214954 1.251 ENSMUST00000031838.7
Igf2bp3
insulin-like growth factor 2 mRNA binding protein 3
chr2_+_164769892 0.998 ENSMUST00000088248.6
ENSMUST00000001439.6
Ube2c

ubiquitin-conjugating enzyme E2C

chr1_-_75219245 0.874 ENSMUST00000079464.6
Tuba4a
tubulin, alpha 4A
chr8_+_58912257 0.848 ENSMUST00000160055.1
BC030500
cDNA sequence BC030500
chr11_+_101316200 0.847 ENSMUST00000142640.1
ENSMUST00000019470.7
Psme3

proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)

chr5_+_93093428 0.752 ENSMUST00000074733.7
Sept11
septin 11
chr11_-_100759942 0.744 ENSMUST00000107363.2
Kcnh4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr7_-_68749170 0.744 ENSMUST00000118110.1
ENSMUST00000048068.7
Arrdc4

arrestin domain containing 4

chr1_-_12991109 0.722 ENSMUST00000115403.2
ENSMUST00000115402.1
Slco5a1

solute carrier organic anion transporter family, member 5A1

chr9_-_121495678 0.660 ENSMUST00000035120.4
Cck
cholecystokinin
chr14_-_20181773 0.649 ENSMUST00000024011.8
Kcnk5
potassium channel, subfamily K, member 5
chr11_-_100759740 0.625 ENSMUST00000107361.2
Kcnh4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr2_+_83644435 0.623 ENSMUST00000081591.6
Zc3h15
zinc finger CCCH-type containing 15
chr5_-_22344690 0.597 ENSMUST00000062372.7
ENSMUST00000161356.1
Reln

reelin

chr5_+_146231211 0.590 ENSMUST00000161181.1
ENSMUST00000161652.1
ENSMUST00000031640.8
ENSMUST00000159467.1
Cdk8



cyclin-dependent kinase 8



chr2_+_160645881 0.585 ENSMUST00000109468.2
Top1
topoisomerase (DNA) I
chr12_+_59131473 0.585 ENSMUST00000177162.1
Ctage5
CTAGE family, member 5
chr4_-_97778042 0.576 ENSMUST00000146447.1
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr4_-_57143437 0.568 ENSMUST00000095076.3
ENSMUST00000030142.3
Epb4.1l4b

erythrocyte protein band 4.1-like 4b

chr1_+_59684949 0.543 ENSMUST00000027174.3
Nop58
NOP58 ribonucleoprotein
chr12_+_59131286 0.533 ENSMUST00000176464.1
ENSMUST00000170992.2
ENSMUST00000176322.1
Ctage5


CTAGE family, member 5


chr2_-_130906338 0.528 ENSMUST00000146975.1
4930402H24Rik
RIKEN cDNA 4930402H24 gene
chr11_+_101316917 0.518 ENSMUST00000151385.1
Psme3
proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)
chr4_-_133756769 0.512 ENSMUST00000008024.6
Arid1a
AT rich interactive domain 1A (SWI-like)
chr16_+_43889936 0.479 ENSMUST00000151183.1
2610015P09Rik
RIKEN cDNA 2610015P09 gene
chr4_-_97584605 0.479 ENSMUST00000107067.1
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr5_-_76951560 0.478 ENSMUST00000140076.1
Ppat
phosphoribosyl pyrophosphate amidotransferase
chr11_+_94629741 0.478 ENSMUST00000021239.6
Lrrc59
leucine rich repeat containing 59
chrX_-_48208566 0.471 ENSMUST00000037960.4
Zdhhc9
zinc finger, DHHC domain containing 9
chr15_+_39076885 0.460 ENSMUST00000067072.3
Cthrc1
collagen triple helix repeat containing 1
chr4_-_97584612 0.460 ENSMUST00000107068.2
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr15_+_72913357 0.449 ENSMUST00000166418.2
Gm3150
predicted gene 3150
chr6_-_47813512 0.447 ENSMUST00000077290.7
Pdia4
protein disulfide isomerase associated 4
chr16_+_43889896 0.438 ENSMUST00000122014.1
ENSMUST00000178400.1
2610015P09Rik

RIKEN cDNA 2610015P09 gene

chr10_+_36974558 0.425 ENSMUST00000105510.1
Hdac2
histone deacetylase 2
chr16_+_32608973 0.416 ENSMUST00000120680.1
Tfrc
transferrin receptor
chr11_-_17211504 0.410 ENSMUST00000020317.7
Pno1
partner of NOB1 homolog (S. cerevisiae)
chr15_-_43170809 0.409 ENSMUST00000063492.6
Rspo2
R-spondin 2 homolog (Xenopus laevis)
chr9_-_48480540 0.398 ENSMUST00000034524.3
Rexo2
REX2, RNA exonuclease 2 homolog (S. cerevisiae)
chr1_-_52499980 0.391 ENSMUST00000164747.1
Nab1
Ngfi-A binding protein 1
chr19_+_41981709 0.391 ENSMUST00000026170.1
Ubtd1
ubiquitin domain containing 1
chr11_-_47379405 0.386 ENSMUST00000077221.5
Sgcd
sarcoglycan, delta (dystrophin-associated glycoprotein)
chr3_-_95882193 0.386 ENSMUST00000159863.1
ENSMUST00000159739.1
ENSMUST00000036418.3
Gm129


predicted gene 129


chr8_+_90828820 0.379 ENSMUST00000109614.2
ENSMUST00000048665.6
Chd9

chromodomain helicase DNA binding protein 9

chr16_+_43889800 0.377 ENSMUST00000132859.1
2610015P09Rik
RIKEN cDNA 2610015P09 gene
chr11_-_51756378 0.374 ENSMUST00000109092.1
ENSMUST00000064297.4
ENSMUST00000109097.2
Sec24a


Sec24 related gene family, member A (S. cerevisiae)


chr5_-_45857473 0.373 ENSMUST00000016026.7
ENSMUST00000067997.6
ENSMUST00000045586.6
Lcorl


ligand dependent nuclear receptor corepressor-like


chr12_+_69372112 0.371 ENSMUST00000050063.7
Arf6
ADP-ribosylation factor 6
chr10_+_22158566 0.361 ENSMUST00000181645.1
ENSMUST00000105522.2
Raet1e
H60b
retinoic acid early transcript 1E
histocompatibility 60b
chr4_+_44756609 0.359 ENSMUST00000143385.1
Zcchc7
zinc finger, CCHC domain containing 7
chr8_+_125734203 0.352 ENSMUST00000034313.6
ENSMUST00000065135.5
Ntpcr

nucleoside-triphosphatase, cancer-related

chr9_-_110654161 0.348 ENSMUST00000133191.1
ENSMUST00000167320.1
Nbeal2

neurobeachin-like 2

chr2_+_18055203 0.340 ENSMUST00000028076.8
Mllt10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr10_+_69534039 0.332 ENSMUST00000182557.1
Ank3
ankyrin 3, epithelial
chr16_-_45158453 0.331 ENSMUST00000181750.1
Slc35a5
solute carrier family 35, member A5
chr1_-_82291370 0.330 ENSMUST00000069799.2
Irs1
insulin receptor substrate 1
chr9_-_106891401 0.326 ENSMUST00000069036.7
Manf
mesencephalic astrocyte-derived neurotrophic factor
chr10_+_36974536 0.326 ENSMUST00000019911.7
Hdac2
histone deacetylase 2
chr8_-_45999860 0.315 ENSMUST00000053558.9
Ankrd37
ankyrin repeat domain 37
chr4_+_132274385 0.301 ENSMUST00000105963.1
Taf12
TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chrX_+_6047453 0.298 ENSMUST00000103007.3
Nudt11
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr11_-_120348513 0.287 ENSMUST00000071555.6
Actg1
actin, gamma, cytoplasmic 1
chr4_-_124693568 0.287 ENSMUST00000030738.7
Utp11l
UTP11-like, U3 small nucleolar ribonucleoprotein, (yeast)
chr12_+_71136848 0.267 ENSMUST00000149564.1
ENSMUST00000045907.8
2700049A03Rik

RIKEN cDNA 2700049A03 gene

chr9_-_114781986 0.266 ENSMUST00000035009.8
ENSMUST00000084867.7
Cmtm7

CKLF-like MARVEL transmembrane domain containing 7

chr11_-_76217490 0.260 ENSMUST00000102500.4
Gemin4
gem (nuclear organelle) associated protein 4
chr4_+_132274369 0.252 ENSMUST00000030731.4
Taf12
TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr3_+_41564880 0.252 ENSMUST00000168086.1
Phf17
PHD finger protein 17
chr19_-_29812952 0.251 ENSMUST00000099525.3
Ranbp6
RAN binding protein 6
chr4_+_32657107 0.245 ENSMUST00000071642.4
ENSMUST00000178134.1
Mdn1

midasin homolog (yeast)

chr4_+_57568144 0.238 ENSMUST00000102904.3
Palm2
paralemmin 2
chr1_-_55088024 0.233 ENSMUST00000027123.8
Hspd1
heat shock protein 1 (chaperonin)
chr11_+_74830920 0.232 ENSMUST00000000291.2
Mnt
max binding protein
chr5_+_66676098 0.228 ENSMUST00000031131.9
Uchl1
ubiquitin carboxy-terminal hydrolase L1
chr19_+_45015168 0.225 ENSMUST00000039016.6
Lzts2
leucine zipper, putative tumor suppressor 2
chrX_-_95444789 0.223 ENSMUST00000084535.5
Amer1
APC membrane recruitment 1
chr9_+_44326804 0.219 ENSMUST00000054708.3
Dpagt1
dolichyl-phosphate (UDP-N-acetylglucosamine) acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr16_+_94085226 0.215 ENSMUST00000072182.7
Sim2
single-minded homolog 2 (Drosophila)
chr16_-_45158624 0.212 ENSMUST00000180636.1
Slc35a5
solute carrier family 35, member A5
chr17_-_90455872 0.203 ENSMUST00000174337.1
ENSMUST00000172466.1
Nrxn1

neurexin I

chr9_-_57606234 0.202 ENSMUST00000045068.8
Cplx3
complexin 3
chr1_-_55088156 0.196 ENSMUST00000127861.1
ENSMUST00000144077.1
Hspd1

heat shock protein 1 (chaperonin)

chr3_+_145576196 0.193 ENSMUST00000098534.4
Znhit6
zinc finger, HIT type 6
chr4_-_132075250 0.187 ENSMUST00000105970.1
ENSMUST00000105975.1
Epb4.1

erythrocyte protein band 4.1

chr17_-_35000848 0.187 ENSMUST00000166828.3
D17H6S56E-5
DNA segment, Chr 17, human D6S56E 5
chr16_+_45158725 0.183 ENSMUST00000023343.3
Atg3
autophagy related 3
chr4_-_129742275 0.183 ENSMUST00000066257.5
Khdrbs1
KH domain containing, RNA binding, signal transduction associated 1
chr4_+_129960760 0.180 ENSMUST00000139884.1
1700003M07Rik
RIKEN cDNA 1700003M07 gene
chr17_-_28486082 0.178 ENSMUST00000079413.3
Fkbp5
FK506 binding protein 5
chr4_+_123282778 0.176 ENSMUST00000106243.1
ENSMUST00000106241.1
ENSMUST00000080178.6
Pabpc4


poly(A) binding protein, cytoplasmic 4


chr11_-_106789157 0.173 ENSMUST00000129585.1
Ddx5
DEAD (Asp-Glu-Ala-Asp) box polypeptide 5
chr17_-_47611449 0.173 ENSMUST00000024783.8
Bysl
bystin-like
chr2_+_115581667 0.172 ENSMUST00000166472.1
ENSMUST00000110918.2
BC052040

cDNA sequence BC052040

chr7_+_46796088 0.170 ENSMUST00000006774.4
ENSMUST00000165031.1
Gtf2h1

general transcription factor II H, polypeptide 1

chr16_-_45158183 0.165 ENSMUST00000114600.1
Slc35a5
solute carrier family 35, member A5
chr18_+_76241580 0.163 ENSMUST00000168423.1
ENSMUST00000091831.6
Smad2

SMAD family member 2

chr7_-_29505447 0.158 ENSMUST00000183096.1
ENSMUST00000085809.4
Sipa1l3

signal-induced proliferation-associated 1 like 3

chr17_-_45573253 0.158 ENSMUST00000165127.1
ENSMUST00000166469.1
ENSMUST00000024739.7
Hsp90ab1


heat shock protein 90 alpha (cytosolic), class B member 1


chr5_+_76951307 0.157 ENSMUST00000031160.9
ENSMUST00000120912.1
ENSMUST00000117536.1
Paics


phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase


chr4_+_107968332 0.154 ENSMUST00000106713.3
Slc1a7
solute carrier family 1 (glutamate transporter), member 7
chr17_-_35000746 0.152 ENSMUST00000163360.1
D17H6S56E-5
DNA segment, Chr 17, human D6S56E 5
chr17_-_87265866 0.148 ENSMUST00000145895.1
ENSMUST00000129616.1
ENSMUST00000155904.1
ENSMUST00000151155.1
ENSMUST00000144236.1
ENSMUST00000024963.3
Mcfd2





multiple coagulation factor deficiency 2





chr3_+_88532314 0.147 ENSMUST00000172699.1
Mex3a
mex3 homolog A (C. elegans)
chr10_+_44268328 0.147 ENSMUST00000039286.4
Atg5
autophagy related 5
chr6_-_23839137 0.144 ENSMUST00000166458.2
ENSMUST00000142913.2
ENSMUST00000115357.1
ENSMUST00000069074.7
ENSMUST00000115361.2
ENSMUST00000018122.7
ENSMUST00000115355.1
ENSMUST00000115356.2
Cadps2







Ca2+-dependent activator protein for secretion 2







chr16_-_45158650 0.141 ENSMUST00000023344.3
Slc35a5
solute carrier family 35, member A5
chr6_+_125096145 0.138 ENSMUST00000112390.1
Chd4
chromodomain helicase DNA binding protein 4
chr1_-_166409773 0.136 ENSMUST00000135673.1
ENSMUST00000079972.6
ENSMUST00000169324.1
ENSMUST00000111411.2
ENSMUST00000128861.1
Pogk




pogo transposable element with KRAB domain




chr19_+_46056539 0.135 ENSMUST00000111899.1
ENSMUST00000099392.3
ENSMUST00000062322.4
Pprc1


peroxisome proliferative activated receptor, gamma, coactivator-related 1


chr11_+_106789235 0.131 ENSMUST00000103068.3
ENSMUST00000018516.4
Cep95

centrosomal protein 95

chr9_-_106891870 0.128 ENSMUST00000160503.1
ENSMUST00000159620.2
ENSMUST00000160978.1
Manf


mesencephalic astrocyte-derived neurotrophic factor


chr11_-_106216318 0.127 ENSMUST00000002043.3
Ccdc47
coiled-coil domain containing 47
chr9_+_40801235 0.124 ENSMUST00000117870.1
ENSMUST00000117557.1
Hspa8

heat shock protein 8

chr10_-_127522428 0.121 ENSMUST00000026470.4
Shmt2
serine hydroxymethyltransferase 2 (mitochondrial)
chr11_-_106788845 0.118 ENSMUST00000123339.1
Ddx5
DEAD (Asp-Glu-Ala-Asp) box polypeptide 5
chr11_+_106216926 0.111 ENSMUST00000021046.5
Ddx42
DEAD (Asp-Glu-Ala-Asp) box polypeptide 42
chrX_+_36328353 0.106 ENSMUST00000016383.3
Lonrf3
LON peptidase N-terminal domain and ring finger 3
chr13_-_75943812 0.104 ENSMUST00000022078.5
ENSMUST00000109606.1
Rhobtb3

Rho-related BTB domain containing 3

chr14_-_89898466 0.099 ENSMUST00000081204.4
Gm10110
predicted gene 10110
chr3_-_95882232 0.094 ENSMUST00000161866.1
Gm129
predicted gene 129
chr7_+_127746775 0.087 ENSMUST00000033081.7
Fbxl19
F-box and leucine-rich repeat protein 19
chr18_+_35553401 0.084 ENSMUST00000181664.1
Snhg4
small nucleolar RNA host gene 4 (non-protein coding)
chr5_-_74702891 0.082 ENSMUST00000117388.1
Lnx1
ligand of numb-protein X 1
chr11_-_72215592 0.081 ENSMUST00000021157.8
Med31
mediator of RNA polymerase II transcription, subunit 31 homolog (yeast)
chr18_+_42511496 0.081 ENSMUST00000025375.7
Tcerg1
transcription elongation regulator 1 (CA150)
chr16_-_45158566 0.079 ENSMUST00000181177.1
Slc35a5
solute carrier family 35, member A5
chr2_-_147186389 0.077 ENSMUST00000109970.3
ENSMUST00000067075.5
Nkx2-2

NK2 homeobox 2

chr17_+_43016536 0.076 ENSMUST00000024708.4
Tnfrsf21
tumor necrosis factor receptor superfamily, member 21
chr11_-_70410010 0.074 ENSMUST00000019065.3
ENSMUST00000135148.1
Pelp1

proline, glutamic acid and leucine rich protein 1

chr8_+_123186235 0.067 ENSMUST00000019422.4
Dpep1
dipeptidase 1 (renal)
chr19_+_6975048 0.067 ENSMUST00000070850.6
Ppp1r14b
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr14_-_118706180 0.065 ENSMUST00000036554.6
ENSMUST00000166646.1
Abcc4

ATP-binding cassette, sub-family C (CFTR/MRP), member 4

chr11_-_52000432 0.064 ENSMUST00000020657.6
Ube2b
ubiquitin-conjugating enzyme E2B
chr18_+_32837225 0.060 ENSMUST00000166214.1
ENSMUST00000053663.9
Wdr36

WD repeat domain 36

chr7_-_46795661 0.057 ENSMUST00000123725.1
Hps5
Hermansky-Pudlak syndrome 5 homolog (human)
chr11_+_120348678 0.052 ENSMUST00000143813.1
0610009L18Rik
RIKEN cDNA 0610009L18 gene
chr11_-_70982987 0.050 ENSMUST00000078528.6
C1qbp
complement component 1, q subcomponent binding protein
chr12_+_8674681 0.045 ENSMUST00000168361.1
ENSMUST00000169750.1
ENSMUST00000163730.1
Pum2


pumilio 2 (Drosophila)


chr5_+_76951382 0.042 ENSMUST00000141687.1
Paics
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase
chr17_+_71204647 0.042 ENSMUST00000126681.1
Lpin2
lipin 2
chr16_-_35490873 0.037 ENSMUST00000023550.7
Pdia5
protein disulfide isomerase associated 5
chr11_+_78178651 0.036 ENSMUST00000092880.7
ENSMUST00000127587.1
ENSMUST00000108338.1
Tlcd1


TLC domain containing 1


chr5_-_137786651 0.033 ENSMUST00000031740.9
Mepce
methylphosphate capping enzyme
chr7_-_46795881 0.018 ENSMUST00000107653.1
ENSMUST00000107654.1
ENSMUST00000014562.7
ENSMUST00000152759.1
Hps5



Hermansky-Pudlak syndrome 5 homolog (human)



chr6_+_49319274 0.016 ENSMUST00000055559.7
ENSMUST00000114491.1
Ccdc126

coiled-coil domain containing 126

chrX_-_7572843 0.014 ENSMUST00000132788.1
Ppp1r3f
protein phosphatase 1, regulatory (inhibitor) subunit 3F
chr9_+_95637601 0.008 ENSMUST00000015498.8
Pcolce2
procollagen C-endopeptidase enhancer 2
chr11_-_72489904 0.005 ENSMUST00000045303.3
Spns2
spinster homolog 2
chr4_+_44756553 0.004 ENSMUST00000107824.2
Zcchc7
zinc finger, CCHC domain containing 7
chr5_+_76974683 0.004 ENSMUST00000101087.3
ENSMUST00000120550.1
Srp72

signal recognition particle 72

chr7_-_34196608 0.002 ENSMUST00000148381.1
ENSMUST00000002710.3
Pdcd2l

programmed cell death 2-like


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0010993 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.2 1.5 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.2 0.6 GO:1903334 positive regulation of protein folding(GO:1903334)
0.2 1.3 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.2 1.2 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.2 0.5 GO:0002014 vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure(GO:0002014)
0.1 0.6 GO:0097477 lateral motor column neuron migration(GO:0097477)
0.1 0.4 GO:0002842 T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) positive regulation of T cell mediated immune response to tumor cell(GO:0002842)
0.1 0.4 GO:0060437 lung growth(GO:0060437)
0.1 0.7 GO:0048254 snoRNA localization(GO:0048254)
0.1 0.3 GO:0070889 platelet alpha granule organization(GO:0070889)
0.1 0.5 GO:0006543 glutamine catabolic process(GO:0006543)
0.1 0.6 GO:0090209 negative regulation of triglyceride metabolic process(GO:0090209)
0.1 0.4 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.1 0.6 GO:0006265 DNA topological change(GO:0006265)
0.1 0.3 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.1 0.3 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.1 0.7 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.1 0.6 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.2 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241)
0.1 0.2 GO:0007412 axon target recognition(GO:0007412)
0.1 0.7 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 0.2 GO:0097278 complement-dependent cytotoxicity(GO:0097278)
0.1 0.5 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.2 GO:0046084 adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0 0.1 GO:0035973 aggrephagy(GO:0035973)
0.0 0.2 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145) regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900175) positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.0 0.2 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 0.2 GO:2001012 mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0 0.5 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.0 0.4 GO:0033572 transferrin transport(GO:0033572)
0.0 0.4 GO:0034143 regulation of toll-like receptor 4 signaling pathway(GO:0034143)
0.0 0.1 GO:0006545 glycine biosynthetic process(GO:0006545)
0.0 0.3 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.1 GO:0072553 terminal button organization(GO:0072553)
0.0 0.2 GO:0019348 dolichol-linked oligosaccharide biosynthetic process(GO:0006488) dolichol metabolic process(GO:0019348)
0.0 0.3 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.1 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0 0.2 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.1 GO:0032696 negative regulation of interleukin-13 production(GO:0032696) negative regulation of interleukin-10 secretion(GO:2001180)
0.0 0.7 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.0 0.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.0 GO:2000508 MDA-5 signaling pathway(GO:0039530) regulation of dendritic cell chemotaxis(GO:2000508) positive regulation of dendritic cell chemotaxis(GO:2000510)
0.0 0.4 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
0.0 0.2 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.1 GO:0006983 ER overload response(GO:0006983)
0.0 1.4 GO:0010950 positive regulation of endopeptidase activity(GO:0010950)
0.0 0.4 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0008537 proteasome activator complex(GO:0008537)
0.1 0.4 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.1 0.6 GO:0001651 dense fibrillar component(GO:0001651)
0.1 0.3 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.8 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 0.4 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.6 GO:0000125 PCAF complex(GO:0000125)
0.1 0.5 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 0.4 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.7 GO:0043203 axon hillock(GO:0043203)
0.0 0.5 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.4 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.2 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.2 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 1.0 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.1 GO:0043202 lysosomal lumen(GO:0043202)
0.0 1.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.2 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.2 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.3 GO:0032797 SMN complex(GO:0032797)
0.0 0.2 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.4 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.4 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.6 GO:0016592 mediator complex(GO:0016592)
0.0 0.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0070552 BRISC complex(GO:0070552)
0.0 0.2 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0035851 histone deacetylase activity (H4-K16 specific)(GO:0034739) Krueppel-associated box domain binding(GO:0035851)
0.2 1.4 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.4 GO:0004998 transferrin receptor activity(GO:0004998)
0.1 0.6 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 0.3 GO:0019776 Atg8 ligase activity(GO:0019776)
0.1 0.7 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.1 0.6 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.1 1.3 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 0.7 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 0.6 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.2 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.1 1.4 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.2 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 0.4 GO:0043559 insulin binding(GO:0043559)
0.0 0.3 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0 0.4 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.1 GO:0031686 A1 adenosine receptor binding(GO:0031686)
0.0 0.9 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.0 0.1 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.0 0.8 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.7 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.4 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.2 GO:0002135 CTP binding(GO:0002135)
0.0 0.5 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 1.0 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 1.5 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.4 GO:0008143 poly(A) binding(GO:0008143) poly(U) RNA binding(GO:0008266)
0.0 0.5 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.0 1.4 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.2 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.1 GO:0070573 metallodipeptidase activity(GO:0070573)
0.0 0.5 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.4 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.0 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.5 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.4 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175) exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.0 0.0 GO:0030984 kininogen binding(GO:0030984)
0.0 0.2 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.0 0.1 GO:0008758 thiamine-pyrophosphatase activity(GO:0004787) UDP-2,3-diacylglucosamine hydrolase activity(GO:0008758) dATP pyrophosphohydrolase activity(GO:0008828) dihydroneopterin monophosphate phosphatase activity(GO:0019176) dihydroneopterin triphosphate pyrophosphohydrolase activity(GO:0019177) dTTP diphosphatase activity(GO:0036218) phosphocholine hydrolase activity(GO:0044606)