Motif ID: Clock
Z-value: 0.504
Transcription factors associated with Clock:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Clock | ENSMUSG00000029238.8 | Clock |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Clock | mm10_v2_chr5_-_76304474_76304548 | -0.03 | 9.0e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 1.0 | GO:0010993 | regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994) |
0.2 | 1.5 | GO:0035726 | common myeloid progenitor cell proliferation(GO:0035726) |
0.2 | 0.6 | GO:1903334 | positive regulation of protein folding(GO:1903334) |
0.2 | 1.3 | GO:0000320 | re-entry into mitotic cell cycle(GO:0000320) |
0.2 | 1.2 | GO:0006344 | maintenance of chromatin silencing(GO:0006344) |
0.2 | 0.5 | GO:0002014 | vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure(GO:0002014) |
0.1 | 0.6 | GO:0097477 | lateral motor column neuron migration(GO:0097477) |
0.1 | 0.4 | GO:0002842 | T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) positive regulation of T cell mediated immune response to tumor cell(GO:0002842) |
0.1 | 0.4 | GO:0060437 | lung growth(GO:0060437) |
0.1 | 0.7 | GO:0048254 | snoRNA localization(GO:0048254) |
0.1 | 0.3 | GO:0070889 | platelet alpha granule organization(GO:0070889) |
0.1 | 0.5 | GO:0006543 | glutamine catabolic process(GO:0006543) |
0.1 | 0.6 | GO:0090209 | negative regulation of triglyceride metabolic process(GO:0090209) |
0.1 | 0.4 | GO:2000189 | positive regulation of cholesterol homeostasis(GO:2000189) |
0.1 | 0.6 | GO:0006265 | DNA topological change(GO:0006265) |
0.1 | 0.3 | GO:0002337 | B-1a B cell differentiation(GO:0002337) |
0.1 | 0.3 | GO:0090273 | regulation of somatostatin secretion(GO:0090273) |
0.1 | 0.7 | GO:0051901 | positive regulation of mitochondrial depolarization(GO:0051901) |
0.1 | 0.6 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
0.1 | 0.2 | GO:0032241 | positive regulation of nucleobase-containing compound transport(GO:0032241) |
0.1 | 0.2 | GO:0007412 | axon target recognition(GO:0007412) |
0.1 | 0.7 | GO:0043252 | sodium-independent organic anion transport(GO:0043252) |
0.1 | 0.2 | GO:0097278 | complement-dependent cytotoxicity(GO:0097278) |
0.1 | 0.5 | GO:0018230 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
0.0 | 0.2 | GO:0046084 | adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084) |
0.0 | 0.1 | GO:0035973 | aggrephagy(GO:0035973) |
0.0 | 0.2 | GO:0007352 | zygotic specification of dorsal/ventral axis(GO:0007352) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145) regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900175) positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224) |
0.0 | 0.2 | GO:0097116 | gephyrin clustering involved in postsynaptic density assembly(GO:0097116) |
0.0 | 0.2 | GO:2001012 | mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012) |
0.0 | 0.5 | GO:0033690 | positive regulation of osteoblast proliferation(GO:0033690) |
0.0 | 0.4 | GO:0033572 | transferrin transport(GO:0033572) |
0.0 | 0.4 | GO:0034143 | regulation of toll-like receptor 4 signaling pathway(GO:0034143) |
0.0 | 0.1 | GO:0006545 | glycine biosynthetic process(GO:0006545) |
0.0 | 0.3 | GO:0010650 | positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) |
0.0 | 0.1 | GO:0072553 | terminal button organization(GO:0072553) |
0.0 | 0.2 | GO:0019348 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) dolichol metabolic process(GO:0019348) |
0.0 | 0.3 | GO:0033148 | positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148) |
0.0 | 0.1 | GO:0021529 | spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) |
0.0 | 0.2 | GO:0089711 | L-glutamate transmembrane transport(GO:0089711) |
0.0 | 0.1 | GO:0032696 | negative regulation of interleukin-13 production(GO:0032696) negative regulation of interleukin-10 secretion(GO:2001180) |
0.0 | 0.7 | GO:0051443 | positive regulation of ubiquitin-protein transferase activity(GO:0051443) |
0.0 | 0.3 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
0.0 | 0.0 | GO:2000508 | MDA-5 signaling pathway(GO:0039530) regulation of dendritic cell chemotaxis(GO:2000508) positive regulation of dendritic cell chemotaxis(GO:2000510) |
0.0 | 0.4 | GO:0001913 | T cell mediated cytotoxicity(GO:0001913) |
0.0 | 0.2 | GO:0043653 | mitochondrial fragmentation involved in apoptotic process(GO:0043653) |
0.0 | 0.1 | GO:0006983 | ER overload response(GO:0006983) |
0.0 | 1.4 | GO:0010950 | positive regulation of endopeptidase activity(GO:0010950) |
0.0 | 0.4 | GO:0036075 | endochondral ossification(GO:0001958) replacement ossification(GO:0036075) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 1.4 | GO:0008537 | proteasome activator complex(GO:0008537) |
0.1 | 0.4 | GO:0089717 | spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717) |
0.1 | 0.6 | GO:0001651 | dense fibrillar component(GO:0001651) |
0.1 | 0.3 | GO:0005899 | insulin receptor complex(GO:0005899) |
0.1 | 0.8 | GO:0090571 | RNA polymerase II transcription repressor complex(GO:0090571) |
0.1 | 0.4 | GO:0016012 | sarcoglycan complex(GO:0016012) |
0.1 | 0.6 | GO:0000125 | PCAF complex(GO:0000125) |
0.1 | 0.5 | GO:0031428 | box C/D snoRNP complex(GO:0031428) |
0.1 | 0.4 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
0.1 | 0.4 | GO:0030127 | COPII vesicle coat(GO:0030127) |
0.0 | 0.1 | GO:0034274 | Atg12-Atg5-Atg16 complex(GO:0034274) |
0.0 | 0.7 | GO:0043203 | axon hillock(GO:0043203) |
0.0 | 0.5 | GO:0002178 | palmitoyltransferase complex(GO:0002178) |
0.0 | 0.4 | GO:1990712 | HFE-transferrin receptor complex(GO:1990712) |
0.0 | 0.2 | GO:0032444 | activin responsive factor complex(GO:0032444) |
0.0 | 0.2 | GO:0070761 | pre-snoRNP complex(GO:0070761) |
0.0 | 1.0 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
0.0 | 0.4 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
0.0 | 0.1 | GO:0031088 | platelet dense granule membrane(GO:0031088) |
0.0 | 0.1 | GO:0043202 | lysosomal lumen(GO:0043202) |
0.0 | 1.3 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
0.0 | 0.2 | GO:0061689 | tricellular tight junction(GO:0061689) |
0.0 | 0.2 | GO:0097524 | sperm plasma membrane(GO:0097524) |
0.0 | 0.3 | GO:0032797 | SMN complex(GO:0032797) |
0.0 | 0.2 | GO:0000439 | core TFIIH complex(GO:0000439) |
0.0 | 0.4 | GO:0071564 | npBAF complex(GO:0071564) |
0.0 | 0.1 | GO:0031084 | BLOC-2 complex(GO:0031084) |
0.0 | 0.4 | GO:0031527 | filopodium membrane(GO:0031527) |
0.0 | 0.6 | GO:0016592 | mediator complex(GO:0016592) |
0.0 | 0.3 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
0.0 | 0.1 | GO:0070552 | BRISC complex(GO:0070552) |
0.0 | 0.2 | GO:0000153 | cytoplasmic ubiquitin ligase complex(GO:0000153) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 0.8 | GO:0035851 | histone deacetylase activity (H4-K16 specific)(GO:0034739) Krueppel-associated box domain binding(GO:0035851) |
0.2 | 1.4 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
0.1 | 0.4 | GO:0004998 | transferrin receptor activity(GO:0004998) |
0.1 | 0.6 | GO:0003917 | DNA topoisomerase type I activity(GO:0003917) |
0.1 | 0.3 | GO:0019776 | Atg8 ligase activity(GO:0019776) |
0.1 | 0.7 | GO:0001094 | TFIID-class transcription factor binding(GO:0001094) |
0.1 | 0.6 | GO:0070326 | very-low-density lipoprotein particle receptor binding(GO:0070326) |
0.1 | 1.3 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
0.1 | 0.7 | GO:0015347 | sodium-independent organic anion transmembrane transporter activity(GO:0015347) |
0.1 | 0.6 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
0.1 | 0.2 | GO:0031694 | alpha-2A adrenergic receptor binding(GO:0031694) |
0.1 | 1.4 | GO:0070064 | proline-rich region binding(GO:0070064) |
0.1 | 0.2 | GO:0003976 | UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976) |
0.1 | 0.4 | GO:0043559 | insulin binding(GO:0043559) |
0.0 | 0.3 | GO:0008486 | diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) |
0.0 | 0.4 | GO:0046703 | natural killer cell lectin-like receptor binding(GO:0046703) |
0.0 | 0.1 | GO:0031686 | A1 adenosine receptor binding(GO:0031686) |
0.0 | 0.9 | GO:0005351 | sugar:proton symporter activity(GO:0005351) |
0.0 | 0.1 | GO:0008732 | threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732) |
0.0 | 0.8 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
0.0 | 0.3 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
0.0 | 0.2 | GO:0030618 | transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618) |
0.0 | 0.7 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
0.0 | 0.4 | GO:0031996 | thioesterase binding(GO:0031996) |
0.0 | 0.2 | GO:0002135 | CTP binding(GO:0002135) |
0.0 | 0.5 | GO:0016864 | protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864) |
0.0 | 1.0 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
0.0 | 1.5 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
0.0 | 0.4 | GO:0008143 | poly(A) binding(GO:0008143) poly(U) RNA binding(GO:0008266) |
0.0 | 0.5 | GO:0019706 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) |
0.0 | 1.4 | GO:0005249 | voltage-gated potassium channel activity(GO:0005249) |
0.0 | 0.2 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
0.0 | 0.1 | GO:0070573 | metallodipeptidase activity(GO:0070573) |
0.0 | 0.5 | GO:0017147 | Wnt-protein binding(GO:0017147) |
0.0 | 0.4 | GO:0098519 | nucleotide phosphatase activity, acting on free nucleotides(GO:0098519) |
0.0 | 0.0 | GO:0008195 | phosphatidate phosphatase activity(GO:0008195) |
0.0 | 0.5 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
0.0 | 0.4 | GO:0000175 | 3'-5'-exoribonuclease activity(GO:0000175) exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896) |
0.0 | 0.0 | GO:0030984 | kininogen binding(GO:0030984) |
0.0 | 0.2 | GO:0005326 | neurotransmitter transporter activity(GO:0005326) |
0.0 | 0.1 | GO:0008758 | thiamine-pyrophosphatase activity(GO:0004787) UDP-2,3-diacylglucosamine hydrolase activity(GO:0008758) dATP pyrophosphohydrolase activity(GO:0008828) dihydroneopterin monophosphate phosphatase activity(GO:0019176) dihydroneopterin triphosphate pyrophosphohydrolase activity(GO:0019177) dTTP diphosphatase activity(GO:0036218) phosphocholine hydrolase activity(GO:0044606) |