Motif ID: Hes1

Z-value: 1.357


Transcription factors associated with Hes1:

Gene SymbolEntrez IDGene Name
Hes1 ENSMUSG00000022528.7 Hes1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hes1mm10_v2_chr16_+_30065333_30065351-0.242.6e-01Click!


Activity profile for motif Hes1.

activity profile for motif Hes1


Sorted Z-values histogram for motif Hes1

Sorted Z-values for motif Hes1



Network of associatons between targets according to the STRING database.



First level regulatory network of Hes1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_12026237 13.047 ENSMUST00000150972.1
Grb10
growth factor receptor bound protein 10
chr11_-_12026732 11.541 ENSMUST00000143915.1
Grb10
growth factor receptor bound protein 10
chr1_+_153652943 5.950 ENSMUST00000041776.5
Rgs8
regulator of G-protein signaling 8
chr10_+_26078255 4.956 ENSMUST00000041011.3
Gm9767
predicted gene 9767
chr4_+_65124174 4.540 ENSMUST00000084501.3
Pappa
pregnancy-associated plasma protein A
chr6_-_90716489 4.512 ENSMUST00000101153.3
Iqsec1
IQ motif and Sec7 domain 1
chr2_-_172043466 3.928 ENSMUST00000087950.3
Cbln4
cerebellin 4 precursor protein
chr1_-_84696182 3.797 ENSMUST00000049126.6
Dner
delta/notch-like EGF-related receptor
chr5_+_26817357 3.685 ENSMUST00000071500.6
Dpp6
dipeptidylpeptidase 6
chr17_-_25797032 3.623 ENSMUST00000165838.1
ENSMUST00000002344.6
Metrn

meteorin, glial cell differentiation regulator

chr4_+_116877376 3.554 ENSMUST00000044823.3
Zswim5
zinc finger SWIM-type containing 5
chr1_-_175692624 3.278 ENSMUST00000027809.7
Opn3
opsin 3
chr12_-_17176888 3.071 ENSMUST00000170580.1
Kcnf1
potassium voltage-gated channel, subfamily F, member 1
chrX_-_141725181 3.036 ENSMUST00000067841.7
Irs4
insulin receptor substrate 4
chr5_+_93093428 2.945 ENSMUST00000074733.7
Sept11
septin 11
chr10_-_127534540 2.936 ENSMUST00000095266.2
Nxph4
neurexophilin 4
chr11_-_66525795 2.905 ENSMUST00000123454.1
Shisa6
shisa homolog 6 (Xenopus laevis)
chrX_-_52165252 2.886 ENSMUST00000033450.2
Gpc4
glypican 4
chr1_+_132316112 2.880 ENSMUST00000082125.5
ENSMUST00000072177.7
Nuak2

NUAK family, SNF1-like kinase, 2

chr11_-_89302545 2.880 ENSMUST00000061728.3
Nog
noggin

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 125 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.7 24.6 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.5 6.0 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.3 5.7 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
1.3 5.3 GO:0003360 brainstem development(GO:0003360)
0.2 4.5 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.3 3.8 GO:0007220 Notch receptor processing(GO:0007220)
0.1 3.7 GO:0090004 positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
1.1 3.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 3.3 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.8 3.2 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.7 2.9 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.5 2.9 GO:0035087 siRNA loading onto RISC involved in RNA interference(GO:0035087)
0.4 2.7 GO:0001842 neural fold formation(GO:0001842)
0.0 2.5 GO:0051384 response to glucocorticoid(GO:0051384)
0.4 2.2 GO:0048133 NK T cell differentiation(GO:0001865) germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138) germline stem cell asymmetric division(GO:0098728)
0.1 2.2 GO:0009409 response to cold(GO:0009409)
0.0 2.1 GO:0051291 protein heterooligomerization(GO:0051291)
0.0 2.1 GO:0071805 potassium ion transmembrane transport(GO:0071805)
0.1 2.0 GO:0045214 sarcomere organization(GO:0045214)
0.2 1.9 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 76 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 10.1 GO:0005615 extracellular space(GO:0005615)
0.1 8.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.2 6.0 GO:0032809 neuronal cell body membrane(GO:0032809)
1.8 5.3 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.0 3.0 GO:0030139 endocytic vesicle(GO:0030139)
0.0 2.9 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 2.6 GO:0005769 early endosome(GO:0005769)
0.6 2.4 GO:0090537 CERF complex(GO:0090537)
0.0 2.3 GO:0005923 bicellular tight junction(GO:0005923)
0.0 2.2 GO:0031225 anchored component of membrane(GO:0031225)
0.0 2.1 GO:0016605 PML body(GO:0016605)
0.0 2.0 GO:0005643 nuclear pore(GO:0005643)
0.0 2.0 GO:0000792 heterochromatin(GO:0000792)
0.1 1.9 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 1.9 GO:0043034 costamere(GO:0043034)
0.3 1.8 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 1.8 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 1.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.3 1.5 GO:0000235 astral microtubule(GO:0000235)
0.1 1.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 92 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 24.6 GO:0001784 phosphotyrosine binding(GO:0001784)
0.2 6.0 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.9 5.3 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.1 5.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.2 4.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 4.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 4.3 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 3.5 GO:0042393 histone binding(GO:0042393)
1.1 3.3 GO:0009881 photoreceptor activity(GO:0009881)
0.5 3.2 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.1 3.0 GO:0005158 insulin receptor binding(GO:0005158)
0.1 2.9 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 2.8 GO:0008017 microtubule binding(GO:0008017)
0.1 2.7 GO:0005112 Notch binding(GO:0005112)
0.0 2.5 GO:0019955 cytokine binding(GO:0019955)
0.1 2.4 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.2 2.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 2.1 GO:0003713 transcription coactivator activity(GO:0003713)
0.3 1.9 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.3 1.8 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733)