Motif ID: Irx5

Z-value: 0.671


Transcription factors associated with Irx5:

Gene SymbolEntrez IDGene Name
Irx5 ENSMUSG00000031737.10 Irx5

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Irx5mm10_v2_chr8_+_92357787_923578010.462.7e-02Click!


Activity profile for motif Irx5.

activity profile for motif Irx5


Sorted Z-values histogram for motif Irx5

Sorted Z-values for motif Irx5



Network of associatons between targets according to the STRING database.



First level regulatory network of Irx5

PNG image of the network

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Top targets:


Showing 1 to 20 of 67 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_139543889 4.893 ENSMUST00000174792.1
ENSMUST00000031523.8
 Uncx

UNC homeobox

chr2_-_79908428 2.070 ENSMUST00000102652.3
ENSMUST00000102651.3
 Pde1a

phosphodiesterase 1A, calmodulin-dependent

chr12_+_38783503 1.886 ENSMUST00000159334.1
 Etv1
ets variant gene 1
chr12_+_55598917 1.845 ENSMUST00000051857.3
 Insm2
insulinoma-associated 2
chr7_-_114927726 1.603 ENSMUST00000059737.2
 Gm6816
predicted gene 6816
chr2_-_79908389 1.599 ENSMUST00000090756.4
 Pde1a
phosphodiesterase 1A, calmodulin-dependent
chr6_+_50110837 1.239 ENSMUST00000167628.1
 Mpp6
membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
chr3_+_124321031 1.231 ENSMUST00000058994.4
 Tram1l1
translocation associated membrane protein 1-like 1
chr9_-_78378725 1.068 ENSMUST00000034900.7
 Ooep
oocyte expressed protein
chr2_-_85035487 1.021 ENSMUST00000028465.7
 P2rx3
purinergic receptor P2X, ligand-gated ion channel, 3
chr14_-_19977040 0.990 ENSMUST00000159028.1
 Gng2
guanine nucleotide binding protein (G protein), gamma 2
chr14_-_19977151 0.962 ENSMUST00000055100.7
ENSMUST00000162425.1
 Gng2

guanine nucleotide binding protein (G protein), gamma 2

chr10_-_88146867 0.869 ENSMUST00000164121.1
ENSMUST00000164803.1
ENSMUST00000168163.1
ENSMUST00000048518.9
 Parpbp



PARP1 binding protein



chr1_-_78968079 0.768 ENSMUST00000049117.5
 Gm5830
predicted pseudogene 5830
chr2_-_101621033 0.737 ENSMUST00000090513.4
 B230118H07Rik
RIKEN cDNA B230118H07 gene
chr3_+_95124476 0.721 ENSMUST00000131597.1
ENSMUST00000005769.6
ENSMUST00000107227.1
 Tmod4


tropomodulin 4


chr14_-_19977249 0.709 ENSMUST00000160013.1
 Gng2
guanine nucleotide binding protein (G protein), gamma 2
chr14_+_48120841 0.682 ENSMUST00000073150.4
 Peli2
pellino 2
chr11_-_68927049 0.674 ENSMUST00000038932.7
 Odf4
outer dense fiber of sperm tails 4
chr5_-_88675190 0.662 ENSMUST00000133532.1
ENSMUST00000150438.1
 Grsf1

G-rich RNA sequence binding factor 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 26 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 4.9 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.2 3.7 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 1.9 GO:0007638 mechanosensory behavior(GO:0007638)
0.1 1.2 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 1.1 GO:0007566 embryo implantation(GO:0007566)
0.3 1.0 GO:1904058 positive regulation of sensory perception of pain(GO:1904058)
0.1 1.0 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 1.0 GO:0007338 single fertilization(GO:0007338)
0.1 0.9 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.2 0.7 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.2 0.7 GO:0070829 heterochromatin maintenance(GO:0070829)
0.1 0.7 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 0.7 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 0.6 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.1 0.5 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.1 0.4 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.1 0.4 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.1 0.4 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.1 0.3 GO:0010986 complement receptor mediated signaling pathway(GO:0002430) GPI anchor release(GO:0006507) positive regulation of lipoprotein particle clearance(GO:0010986)
0.0 0.3 GO:0097094 craniofacial suture morphogenesis(GO:0097094)

Gene overrepresentation in cellular_component category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.2 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 1.0 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 1.0 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 1.0 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 0.7 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.7 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.7 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.5 GO:0031430 M band(GO:0031430)
0.0 0.5 GO:0031225 anchored component of membrane(GO:0031225)
0.1 0.4 GO:0070876 SOSS complex(GO:0070876)
0.0 0.4 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.4 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.3 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 0.2 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 0.1 GO:0000137 Golgi cis cisterna(GO:0000137)

Gene overrepresentation in molecular_function category:

Showing 1 to 16 of 16 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 3.7 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 2.7 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 1.2 GO:0004385 guanylate kinase activity(GO:0004385)
0.2 1.0 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.2 1.0 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.2 0.7 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.2 0.7 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.1 0.7 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.4 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.1 0.4 GO:0045545 syndecan binding(GO:0045545)
0.0 0.4 GO:0070034 telomerase RNA binding(GO:0070034)
0.1 0.3 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.3 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.2 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)