Motif ID: Hoxa9_Hoxb9

Z-value: 0.444

Transcription factors associated with Hoxa9_Hoxb9:

Gene SymbolEntrez IDGene Name
Hoxa9 ENSMUSG00000038227.9 Hoxa9
Hoxb9 ENSMUSG00000020875.8 Hoxb9



Activity profile for motif Hoxa9_Hoxb9.

activity profile for motif Hoxa9_Hoxb9


Sorted Z-values histogram for motif Hoxa9_Hoxb9

Sorted Z-values for motif Hoxa9_Hoxb9



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa9_Hoxb9

PNG image of the network

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Top targets:


Showing 1 to 20 of 122 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_142661858 1.271 ENSMUST00000145896.2
 Igf2
insulin-like growth factor 2
chr19_-_57197377 0.858 ENSMUST00000111546.1
 Ablim1
actin-binding LIM protein 1
chr19_-_57197435 0.848 ENSMUST00000111550.1
 Ablim1
actin-binding LIM protein 1
chr15_+_25773985 0.830 ENSMUST00000125667.1
 Myo10
myosin X
chr16_-_52454074 0.650 ENSMUST00000023312.7
 Alcam
activated leukocyte cell adhesion molecule
chr6_+_49822710 0.617 ENSMUST00000031843.6
 Npy
neuropeptide Y
chr15_+_85510812 0.496 ENSMUST00000079690.2
 Gm4825
predicted pseudogene 4825
chr11_-_79504078 0.471 ENSMUST00000164465.2
 Omg
oligodendrocyte myelin glycoprotein
chr2_-_33086366 0.454 ENSMUST00000049618.2
 Garnl3
GTPase activating RANGAP domain-like 3
chr6_-_143947092 0.431 ENSMUST00000144289.1
ENSMUST00000111748.1
 Sox5

SRY-box containing gene 5

chr19_-_57197496 0.425 ENSMUST00000111544.1
 Ablim1
actin-binding LIM protein 1
chr2_-_31845925 0.419 ENSMUST00000028188.7
 Fibcd1
fibrinogen C domain containing 1
chr6_-_143947061 0.419 ENSMUST00000124233.1
 Sox5
SRY-box containing gene 5
chr2_-_33087169 0.404 ENSMUST00000102810.3
 Garnl3
GTPase activating RANGAP domain-like 3
chr1_+_194619815 0.357 ENSMUST00000027952.5
 Plxna2
plexin A2
chr7_-_101870778 0.347 ENSMUST00000001882.4
ENSMUST00000126204.1
ENSMUST00000155311.1
ENSMUST00000106983.1
ENSMUST00000123630.1
 Folr1




folate receptor 1 (adult)




chr19_-_57197556 0.338 ENSMUST00000099294.2
 Ablim1
actin-binding LIM protein 1
chrX_+_159840463 0.337 ENSMUST00000112451.1
ENSMUST00000112453.2
 Sh3kbp1

SH3-domain kinase binding protein 1

chr13_+_16014457 0.302 ENSMUST00000164993.1
 Inhba
inhibin beta-A
chr3_+_98280427 0.300 ENSMUST00000090746.2
ENSMUST00000120541.1
 Hmgcs2

3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 31 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.6 GO:0030032 lamellipodium assembly(GO:0030032)
0.2 1.3 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 0.8 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.8 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.7 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 0.6 GO:0019732 antifungal humoral response(GO:0019732)
0.0 0.5 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 0.4 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.1 0.3 GO:0061626 pharyngeal arch artery morphogenesis(GO:0061626)
0.1 0.3 GO:0042636 negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279)
0.1 0.3 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.0 0.3 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.0 0.3 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.0 0.3 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.3 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.3 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.3 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.1 0.2 GO:0006538 glutamate catabolic process(GO:0006538)
0.1 0.2 GO:0070366 regulation of hepatocyte differentiation(GO:0070366)
0.0 0.2 GO:0017121 phospholipid scrambling(GO:0017121)

Gene overrepresentation in cellular_component category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.5 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.7 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.4 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 0.3 GO:0043512 inhibin A complex(GO:0043512)
0.0 0.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.2 GO:0033269 internode region of axon(GO:0033269)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.1 GO:0071439 clathrin complex(GO:0071439)
0.0 0.1 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.1 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 22 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.9 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.8 GO:0030507 spectrin binding(GO:0030507)
0.1 0.4 GO:0008061 chitin binding(GO:0008061)
0.0 0.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.3 GO:0051870 methotrexate binding(GO:0051870)
0.1 0.3 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.3 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.3 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.3 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.2 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.2 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.1 GO:0004556 alpha-amylase activity(GO:0004556)
0.0 0.1 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.1 GO:0009378 four-way junction helicase activity(GO:0009378)